scholarly journals Prevalence of anaemia in pregnancy at antenatal care booking in a teaching hospital in Southern Nigeria

Author(s):  
Esther Ijeoma Nonye-Enyidah ◽  
Basil Omieibi A. Altraide ◽  
Awopola I. Jumbo

Background: Anaemia in pregnancy is the commonest haematological condition seen in pregnant women in most developing countries. It is a global public health problem causing maternal and fetal morbidity and mortality. Objective was to determine the prevalence of anaemia and associated socio-demographic factors among pregnant women at booking at Rivers State University Teaching Hospital (RSUTH).Methods: A retrospective study conducted from 1st January, 2015 to 31st December, 2020 at the antenatal clinic (ANC) of RSUTH. The laboratory records of 9990 pregnant women who booked for antenatal care were retrieved and reviewed. This included the socio-demographic characteristics and routine investigations. Data was extracted, coded and analyzed using the IBM statistical package for social sciences (SPSS) version 23.0 (Armonk, NY). P value <0.05 was considered statistically significant.Results: Total number of women who booked for antenatal care was 9990 women. Of this, 8635 women were anaemic giving a prevalence rate of 86.4%. Mild anaemia was seen in 7061 (70.68%); 1546 (15.48%) had moderate anaemia and 28 (0.28%) had severe anaemia. Of 8635 (86.4%) women who were anaemic, 1647 (19.07%), 5036 (58.32%) and 1952 (22.61%) were seen in the first, second and third trimesters respectively. Mean and modal packed cell volume (PCV) were 29±3.1% and 29% respectively. The range of PCV was 18-42%. Mean age was 31±4.7 years and age range was 15-48 years. Modal parity was zero. Nulliparous and multiparous women accounted for 3586 (35.9%) and 3751 (37.5%) of the women respectively. There was a significant correlation between anaemia and age, parity, level of education, occupation and genotype at booking.Conclusions: The prevalence of anaemia was unacceptably high. There is need for education on anaemia at the antenatal clinics and close monitoring of the interventional measures put in place to prevent anaemia in pregnancy, in order to improve the pregnancy outcome.

Author(s):  
P. A. Awoyesuku ◽  
D. A. Macpepple ◽  
B. O. Altraide ◽  
D. H. John

Background: Infection with hepatitis B (HBV) and human immunodeficiency virus (HIV) are global public health problems. These infections during pregnancy increase the risk of maternal morbidity and mortality, and also pose a risk to the fetus due to mother to child transmission. Objective: To determine the prevalence of seropositive HIV and HBsAg cases amongst pregnant women at the Rivers State University Teaching Hospital (RSUTH). Methodology: A retrospective review of hospital and laboratory records of all pregnant women booked at RSUTH in two years, from May 2017 to April 2019, was carried out. Data on patients’ age, parity and educational level and reactivity of HIV and HBsAg test at booking were retrieved using structured proforma and analyzed using Epi Info Version 7. Test for significance using Chi-square was set at a significant level of P<0.05. Results: 3560 patients had HIV and HBsAg screening out of which 148 (4.2%) and 9 (0.3%) respectively were positive. The comorbidity rate in this study was 0.06%. The mean age was 31.5±4.7 years and the mean gestational age at booking was 22.1±6.8 weeks. There was no significant relationship between their age (χ2 = 2.690, p-value=0.442) and parity (χ2 = 3.759, p-value = 0.145) with HIV seropositivity, but these were significant for HBsAg (χ2 = 13.691, p-value = 0.003) (χ2 = 13.121, p-value=0.001).  Educational status was significant for HIV (χ2 = 16.188, p-value=0.000) but not for HBsAg (χ2 = 0.229, p-value=0.892). Conclusion: The seroprevalence rate of HIV and HBsAg in this study were low. HIV seroprevalence was significantly affected by lower education, while HBsAg seroprevalence was significantly affected by younger maternal age and nulliparity. Continued screening of pregnant women for these infections remains valuable and further community-based studies to identify risk factors are recommended.


Author(s):  
Muhammad Baffah Aminu ◽  
Mohammed Alkali ◽  
Bala M. Audu ◽  
Toyin Abdulrazak

Background: Pregnant women are at increasing risk of GI symptoms such as nausea, vomiting and heartburns, most of these symptoms are as a result of the hormonal and physical changes associated with pregnancy. This study aimed to determine prevalence of gastrointestinal symptoms (GI) among pregnant women attending booking clinic at a Northeastern Nigerian Teaching Hospital.Methods: The study was a cross-sectional, questionnaire-based survey of four hundred and fifty-two pregnant women booking for antenatal care. Their sociodemographic variables as well as the presence or absence of gastrointestinal symptoms in index pregnancy were obtained at by the use of researcher-administered questionnaire. Data were analyzed and presented as frequencies and percentages. A 5% significance level (p <0.05) to test associations.Results: Two fifty-five women had heart burns (56.4%) while 235 (52.0%) had nausea in pregnancy, these were observed to be the most prevalent GI symptoms among the women. Diarrhea and hemorrhoids were the uncommon GI symptoms in the study population constituting 406 (89.5%), and 360 (79.6%) respectively. Easy fullness was noted in 39.8% of the women while vomiting was in 41.8% and constipation in 29% of the respondents. A significant association was observed (p value <0.05) between parity and development of anorexia and hemorrhoids in pregnancy (p values of 0.049 and 0.051 respectively) but not for the other symptoms.Conclusions: GI symptoms are common in pregnancy, the most prevalent symptoms are that of heart burns and nausea, while diarrhea is relatively uncommon.


Author(s):  
P. A. Awoyesuku ◽  
D. A. MacPepple ◽  
N. J. Kwosah

Background: Untreated maternal syphilis is strongly associated with adverse birth outcomes. The WHO recommends routine serological screening in pregnancy. Some workers have advised a reappraisal of this practice, having demonstrated low seroprevalence in their antenatal population. Objective: To determine the prevalence of seropositive VDRL cases amongst pregnant women at the Rivers State University Teaching Hospital (RSUTH) in order to justify the need and cost-effectiveness for continued routine syphilis screening using VDRL alone. Methodology: A retrospective review of hospital and laboratory records of all pregnant women booked for antenatal care (ANC) at RSUTH in a two-year period, from May 2017 to April 2019, was carried out. Data on patients’ age, parity and educational level, and reactivity of VDRL test at booking were retrieved using structured pro-forma and analyzed using Epi Info Version 7. Test for significance using Chi-square was set at significant level of P<0.05. Results: 3560 clinic patients had VDRL screening out of which 63 were positive. The overall prevalence rate in this study was 1.8%. The mean age was 31.5±4.7 years and the mean gestational age at booking was 22.1±6.8 weeks. There was no significant relationship between their age (χ2 = 0.403, p-value=0.940), parity (χ2 = 3.707, p-value=0.0.157), and educational status (χ2 = 1.853, p-value=0.396), and seropositivity. The cost of VDRL test per patient in RSUTH is $3, to detect the 63 cases the sum of $10,680 was spent. Conclusion: The seroprevalence rate of syphilis in this study was low. Initial screening using VDRL alone is neither justified nor cost effective. Selective screening based on risk factors and specific test with TPHA is recommended.


Author(s):  
Chuka N. Obi ◽  
Vitus O. Obi ◽  
Johnbosco I. Nwafor ◽  
Blessing I. Onwe ◽  
Victor U. Onuchukwu ◽  
...  

Background: Preeclampsia is a pregnancy specific multisystem disease and it is associated with increased maternal and perinatal morbidity and mortality. Any factor(s) which could reliably predict the likelihood of serious complications would be very valuable in predicting the associated adverse outcome. Objective of this study compare maternal and fetal outcomes of preeclamptic patients with normotensive control in Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Nigeria.Method: This was a 4-year retrospective case-control study of the pregnancy outcomes among preeclamptic and normotensive women managed in our facility between 1st January 2012 and 31st December 2015. Data analysis was done using Epi Info software 7.2.1.Results: During the study period there were 6,585 deliveries among which 92 of the patients were managed for preeclampsia. This gives a prevalence of 1.4% or 14 per 1000 deliveries. There was no difference in the age and parity of the control. Most of the preeclamptic patients managed over the study period were unbooked for antenatal care in the facility (p value <0.0001). Preeclamptic patients were more likely to be delivered preterm (p value was <0.0001), and by caesarean section compared to the control. They were also more likely to have babies with low birth weights and poorer fetal outcomes. There was no difference in maternal mortality between both groups.Conclusion: Preeclampsia is associated with the unbooked status and poorer perinatal outcome compared with normotensive women. There is need to encourage women to book for antenatal care for prompt identification and management of these women.


2021 ◽  
Author(s):  
Henry Sembatya ◽  
Justine Namuli ◽  
Judith Ajeani ◽  
Sam Ononge

Abstract Background: Psychological distress (PD) among pregnant women has a bearing both on the mother and the outcome of the pregnancy and is thus a public health problem. It is a precursor for other severe mental health conditions that include anxiety, depression, bipolar disorder and so if screened and diagnosed early it can prevent progress to severe mental illness. PD has however not been screened among pregnant women and thus no available data in Uganda. The objective of this study was to determine the prevalence and factors associated with PD among pregnant women at Kawempe hospital Uganda.Methods: A cross sectional study was conducted among 530 pregnant women attending antenatal care at Kawempe hospital Uganda. The SRQ-20 tool was used to screen for PD and data on socio-demographic and clinical factors was collected using a. socio-demographic questionnaire and medical records respectively. Descriptive statistics were applied to determine the prevalence of PD and multivariable logistic regression analysis was used to assess for factors associated with PD among pregnant women.Results: The prevalence of PD was 19.1% , while having a fair/bad relationship with the spouse (P-value =0.007), a low monthly income (p-value = 0.013), and having less than two meals a day (P-value =0.022). were independently associated with PDConclusion: Approximately one in five pregnant women receiving ANC at Kawempe hospital has PD. This study therefore supports the need for integration of mental health assessment into the antenatal care package of women at Kawempe hospital and Uganda at large


Author(s):  
P. A. Awoyesuku ◽  
C. Ohaka ◽  
B. Ngeri

Background: Anemia in pregnancy is an important public health problem worldwide. Despite the efforts of government and health bodies, maternal anemia continues to be a common cause of morbidity and mortality. This suggests that other factors contribute to the high prevalence of anemia in pregnancy despite the intervention efforts. Objective: This study sought to determine the prevalence and anemic status of pregnant women at booking, to assess their knowledge of anemia and attitude to anemia prevention measures. And to determine associated risk factors for anemia and if there is a correlation between anemic status and level of knowledge/attitude to anemia prevention Methodology: An institutional-based, cross-sectional study was carried out. 322 consenting participants between 18-48 years were interviewed at booking using a structured questionnaire. Information on socio-demographic characteristics; their knowledge on causes, symptoms, prevention, and complications of anemia in pregnancy; and information on attitude towards anemia prevention strategies were collected. The PCV and HIV results of the women were retrieved. Data were entered into an Excel spreadsheet and analyzed with SPSS version 20. Associations between different variables were determined using Fisher's exact test or Chi-square test, as appropriate, and logistic regression was used to test statistical significance at P<0.05. Results: Their mean age±SD was 31.65±4.72 years and the median parity was 1.Of the 322 women, 194(60.2%) were anemic, with 186(57.8%) having mild anemia. There was no significant association between anemia and age, marital status, education, employment, parity, pregnancy interval and socio-economic status, but there was a significant association between gestational age and HIV status, with only gestational age remaining significant after logistic regression. The relationship between anemia and knowledge and attitude was not significant, but the higher educational status was significantly related to knowledge of anemia and its prevention. Conclusion: The prevalence of anemia in this study was high. Despite good knowledge and attitude to anemia prevention, late booking for ANC caused a significant association with the occurrence of anemia. Efforts are needed to encourage early booking and early commencement of iron and folic acid supplements.


Med Phoenix ◽  
2020 ◽  
Vol 5 (1) ◽  
pp. 54-63
Author(s):  
Ravi Kumar Shah ◽  
Jagat Prasad Deep ◽  
Zarin Rahman ◽  
Pravin Shah ◽  
Neha Nayak ◽  
...  

Background: Anaemia in pregnancy is a global health challenge. It is the commonest medical disorder of pregnancy and a major cause of morbidity and mortality in developing countries. Main cause of anaemia in obstetrics is iron deficiency. There are specific risks for the mother and the fetus such as intrauterine growth retardation, prematurity, and blood transfusion. Hence, the importance of giving iron in the antenatal period and to be continued postnatally. Objectives: The study was conducted to determine the overall prevalence of anaemia among pregnant women presenting in third trimester and its effect on pregnancy outcome. Methods: This is a cross sectional descriptive study done at National Medical College & Teaching Hospital from September 2015 to August 2016. During the study period 2048 pregnant women attended antenatal clinic in third trimester. Among 2048, 1200 were booked cases and out of these women with haemoglobin less than 11gm/dl were labeled as anaemia. The prevalence was calculated along with the maternal and fetal outcome. Result: Among 2048, 1200 were booked cases, 368 (30.66%) were anemic, 66.30% were multigravida, 67.93% in age group of 21-30 years, 284 patients came for delivery. In 14.08% patients there was preterm labour, apgar score less than 7 in 66.19% babies. Majority of neonate weighed between 2.0 - 2.5kg (49.29%). Perinatal deaths were 2.81%. Conclusion: Anaemia in pregnancy need awareness about early and regular antenatal care with oral iron supplementation. Correction of anaemia will reduce the maternal and fetal complications.  


PLoS ONE ◽  
2021 ◽  
Vol 16 (4) ◽  
pp. e0250350
Author(s):  
Yaa Nyarko Agyeman ◽  
Sam Newton ◽  
Raymond Boadu Annor ◽  
Ellis Owusu-Dabo

In 2012 the World Health Organisation (WHO) revised the policy on Intermittent Preventive Treatment with Sulphadoxine Pyrimethamine (IPTp-SP) to at least three doses for improved protection against malaria parasitaemia and its associated effects such as anaemia during pregnancy. We assessed the different SP dosage regimen available under the new policy to determine the dose at which women obtained optimal protection against anaemia during pregnancy. A cross-sectional study was conducted among pregnant women who attended antenatal clinic at four different health facilities in Ghana. The register at the facilities served as a sampling frame and simple random sampling was used to select all the study respondents; they were enrolled consecutively as they kept reporting to the facility to receive antenatal care to obtain the required sample size. The haemoglobin level was checked using the Cyanmethemoglobin method. Multivariable logistic regression was performed to generate odds ratios, confidence intervals and p-values. The overall prevalence of anaemia among the pregnant women was 62.6%. Pregnant women who had taken 3 or more doses of IPTp-SP had anaemia prevalence of 54.1% compared to 66.6% of those who had taken one or two doses IPTp-SP. In the multivariable logistic model, primary (aOR 0.61; p = 0.03) and tertiary education (aOR 0.40; p = <0.001) decreased the odds of anaemia in pregnancy. Further, pregnant women who were anaemic at the time of enrollment (aOR 3.32; p = <0.001) to the Antenatal Care clinic and had malaria infection at late gestation (aOR 2.36; p = <0.001) had higher odds of anaemia in pregnancy. Anaemia in pregnancy remains high in the Northern region of Ghana. More than half of the pregnant women were anaemic despite the use of IPTp-SP. Maternal formal education reduced the burden of anaemia in pregnancy. The high prevalence of anaemia in pregnancy amid IPTp-SP use in Northern Ghana needs urgent attention to avert negative maternal and neonatal health outcomes.


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