scholarly journals Clinico-radiological profile of abdominal tuberculosis in HIV/AIDS patients-a study from rural central India

2017 ◽  
Vol 5 (5) ◽  
pp. 1980 ◽  
Author(s):  
Nisar A. Wafai ◽  
Sudhir K. Yadav ◽  
Prem S. Singh ◽  
Manoj Kumar ◽  
Prafulla K. Singh ◽  
...  
Keyword(s):  
Imaging Modality ◽  
Central India ◽  
Abdominal Tuberculosis ◽  
Cd4 Count ◽  
Common Finding ◽  
Non Invasive ◽  
Significant Difference ◽  
Average Size ◽  
Loss Of Appetite ◽  
Hiv Aids

Background: One of the major challenge of present era is dual epidemic of HIV/AIDS and tuberculosis. With immunosuppression, risk of opportunistic diseases increases in these patients and tuberculosis is most common opportunistic infection. The prevalence of abdominal tuberculosis seems to be rising, particularly due to increasing prevalence of HIV infection. The diagnosis of abdominal tuberculosis can often be difficult and it remains underdiagnosed, in view of its nonspecific manifestations. The investigations involved in its diagnosis are expensive and time consuming, however, ultrasonography (USG) is an affordable, non-invasive and widely available modality which can be of help in the diagnosis of abdominal tuberculosis. Therefore, this study was undertaken to evaluate clinical and USG finding among Abdominal Tuberculosis patients with HIV/AIDS.Methods: After informed consent, patients underwent thorough history taking and clinical examination followed by high quality USG abdomen and other biochemical and haematological tests including CD4 count. Follow up USG abdomen was done at time of completion of course of ATT and data was analysed.Results: 45 were found to have abdominal tuberculosis. Of these patients, 31(68.9%) were male and 14 (31.1%) were female. Mean age of HIV-abdominal TB was 34.27±9.66 years. most common symptoms were weight loss 41(91.1%), loss of appetite 38(84.4%), fever       32(71.1%), generalized weakness 30(66.7%) and abdominal pain 27(60.0%). On USG abdomen, intraabdominal lymphadenopathy was most common finding found in 44(97.8%). Average size of enlarged lymph node was 3.1+-1.0 cm. Mesenteric lymphnodes were enlarge in 40(88.89%), paraaortic 8(17.78%), retroperitoneal 4(8.89%) while peripancreatic and porta hepatic in 3(6.67%). splenomegaly was noted in 14(31.1%) cases. Hepatomegaly was found in 6 cases, who all were male. Ascites was evident in 5(11.1%) patients. Extensive involvement, defined as involvement of two or more intraabdominal sites, was found 24(53.3%) cases. There was no statistically significant difference found among these USG findings and CD4 count.Conclusions: The findings of lymphadenopathy (size>15mm) and hypoechoic/necrotic echotexture, hepatosplenomegaly with hypoechoic lesions in ultrasonography are suggestive of abdominal tuberculosis in HIV infected patients with unexplained nonspecific symptoms and low CD4 count.  However, above findings are not standardized and inability to confirm the diagnosis of tuberculosis by direct microscopy and culture is the limitation of this study. Ultrasonography is an affordable, widely available, non-invasive imaging modality which may be optimally utilized for the diagnosis of abdominal tuberculosis in HIV infected patients, especially in the rural setup where microbiological and other sophisticated radiological investigations have limited availability.

scholarly journals Influence of sex and age on sonographic infant hip indices

2014 ◽  
Vol 2 (4) ◽  
Author(s):  
Kakale SB ◽  
Tabari AM ◽  
Isyaku K ◽  
Yunusa A
Keyword(s):  
Imaging Modality ◽  
Alpha Angle ◽  
Late Presentation ◽  
Radiology Department ◽  
Age Group ◽  
Hip Joints ◽  
Non Invasive ◽  
Significant Difference ◽  
Males And Females ◽  
The Mean

Ultrasound is a non-invasive, cheap and readily available imaging modality for studying the infant hip. Early detection of developmental hip subluxation, acetabular dysplasia and the prevention of late presentation of a developmentally dislocated hip with consequent secondary premature degenerative arthritis are goals that all practitioners should strive for. Provision of axial indices of alpha and beta angles of the infant hip joint in Kano, Nigeria using ultrasonography to establish a normogram as reference values for further studies is the objective of this study. This descriptive prospective study was conducted at the Radiology Department of Aminu Kano Teaching Hospital, Kano state, Nigeria. Successive four hundred appropriately consented infants were recruited for this study. The axial angle relationships of both hip joints were measured using 7.5 MHz linear transducer of Mindray DP-8800 Digital plus ultrasound machine. The mean alpha and beta angles for both hips in females were 56.590 and 49.580 respectively while those for males were 56.730 and 50.530 respectively. Minimum and maximum alpha angle for both hips ranged from 380 to 780 while the beta angles ranged 290 to 660 respectively. The age group 1-3 months has the highest frequency of respondents (251) while age group 10 - 12 months has the lowest (22). There was no statistically significant difference in the alpha and beta angles between males and females hips and age of the infants did not affect the hip indices. The study showed no statistical significant difference in the measured alpha and beta angles between males and females. Age of measurement in infants did not affect the hip indices.

scholarly journals Characteristics and treatment outcomes of HIV infected elderly patients enrolled in Kisii Teaching and Referral Hospital, Kenya

2020 ◽  
Vol 20 (4) ◽  
pp. 1537-45
Author(s):  
Benuel Nyagaka ◽  
Stanslaus Kiilu Musyoki ◽  
Lucy Karani ◽  
Anthony Kebira Nyamache
Keyword(s):  
Viral Load ◽  
Elderly Patients ◽  
Clinical Care ◽  
Cd4 Count ◽  
Referral Hospital ◽  
People Living With Hiv ◽  
Keywords Hiv ◽  
Significant Difference ◽  
Baseline Characteristics ◽  
Hiv Aids

Background: A better understanding of the baseline characteristics of elderly people living with HIV/AIDS (PLWHA) is relevant because the world’s HIV population is ageing. Objectives: This study aimed to evaluate the baseline characteristics of PLWHA aged ≥ 50years at recruitment to HIV/ AIDS clinic compared against the viral load (VL) and CD4 count among patients attending Kisii Teaching and Referral Hospital (KTRH), Kenya. Methods: We retrospectively evaluated temporal inclinations of CD4 levels, viral load change and baseline demographic characteristics in the electronic records at the hospital using a mixed error-component model for 1329 PLWHA attending clinic between January 2008 and December 2019. Results: Findings showed a significant difference in the comparison between baseline VL and WHO AIDS staging (p=0.026). Overall VL levels decreased over the period significantly by WHO AIDS staging (p<0.0001). Significant difference was ob- served by gender (p<0.0001), across age groups (p<0.0001) and baseline CD4 counts (p=0.003). There were significant differences in WHO staging by CD4 count >200cell/mm3 (p=0.048) and residence (p=0.001). Conclusion: Age, WHO AIDS staging, gender and residence are relevant parameters associated with viral load decline and CD4 count in elderly PLWHA. A noticeable VL suppression was attained confirming possible attainment of VL suppression among PLWHA under clinical care. Keywords: HIV infected elderly patients; Kisii Teaching and Referral Hospital, Kenya.

scholarly journals Epidemiological profile of candidiasis in HIV/AIDS patients in a tertiary care hospital

2020 ◽  
Vol 7 (12) ◽  
pp. 4858
Author(s):  
Megh S. Dhakad ◽  
Ravinder Kaur ◽  
Ritu Goyal ◽  
Preena Bhalla ◽  
Richa Dewan
Keyword(s):  
Fungal Infections ◽  
Oral Candidiasis ◽  
Tertiary Care ◽  
Cd4 Count ◽  
Clinical Samples ◽  
Care Hospital ◽  
Cd4 Counts ◽  
Epidemiological Profile ◽  
Loss Of Appetite ◽  
Hiv Aids

Background: Clinical research in fungal infections is largely a neglected area in health care settings in India. Candida species cause diseases ranging from mucosal infections to systemic mycoses depending on host’s immune status. Aim of this study was to evaluate the clinico-epidemiological profile of candidiasis, and their correlation with an immunological profile in HIV/AIDS patients.Methods: Clinical details and investigations of 200 symptomatic, confirmed HIV-positive patients, suspected of having candidiasis were recorded and analyzed. Relevant clinical samples depending on the organ system involved were collected and subjected to direct microscopy, culture isolation and serology. Identification and speciation of the isolates was done by biochemical methods as per standard recommended procedures. CD4-count was determined by flow cytometry using Fluorescent Activated Cell Sorter Count system.Results: Patients ranged from 17-65 years with a mean age of 33.83±9.07 years. Most common clinical presentations were seen to be white oral patches (82%), weight loss (79%), fever (67%), loss of appetite (53%), headache (51.5%), cough (38.5%) and diarrhea (30%).  Gastrointestinal system (35%) was the most commonly involved system. The CD4-counts ranged from 16-1033 cells/μl. 93 (46.5%) patients had CD4-counts <200 cells/μl, while CD4-count <100 cells/μl was seen in 40 (20%) and CD4-count <50 cells/μl in 20 (10%). Candidiasis was detected in 60% of the patients. Yeasts isolated were C. albicans (82.51%), C. tropicalis (6.29%), C. krusei (4.89%), C. parapsilosis (3.49%), and C. glabrata (2.79%).Conclusions: C. albicans was predominant species and presence of oral candidiasis is a matter of concern. Early and accurate diagnosis of candidiasis is one of the keys helps for the success of effective HIV/AIDS disease management. 

scholarly journals Functional status and CD4 count of patients living with HIV AIDS attending ART centre at tertiary care hospital of central India

2018 ◽  
Vol 6 (3) ◽  
pp. 908
Author(s):  
Rushali Rajan Lilare ◽  
Uday Wasudeorao Narlawar ◽  
Ganpat Mirdude
Keyword(s):  
Functional Status ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Central India ◽  
Cd4 Count ◽  
People Living With Hiv ◽  
Care Hospital ◽  
Age Group ◽  
Living With Hiv ◽  
Hiv Aids

Background: The present study was retrospective record based, conducted with the aim of assessing the functional status and CD4 count of patients living with HIV/AIDS attending the ART Centre in special reference to gender difference at tertiary care hospital of central India.Methods: Study subjects were people living with HIV/AIDS registered at ART centre at tertiary care hospital of central India in the past three years (1 Jan. 2011 to 31 Dec. 2013). The study duration was from September 2013 to January 2015. This study was conducted on 2042 PLHIV subjects whose records were available for study.Results: In our study there were 58.37% males, 42.4% female and 0.15% transgender. Majority of male 42.45% were between 35-44 years of age group whereas 36.95% females were between 25-34years of age group. Majority of males 22.16% were non agricultural labourer whereas females 78.32% were homemaker. Majority of males 37.41% were in the WHO clinical stage 3 whereas majority of females 36.70% were in stage 1 at the start of ART treatment. About 84.30% females and 76.9% male were working at the start of ART. Majority of males 31.12% and 38.79% had CD4 count between 51-150 at the time of ART registration and at the time of ART treatment respectively. Majority of males 42.62% and 29.34% had CD4 count >350 and between151-250 respectively. About 16.53 % males and 8.97% female were died at the time of data collection.Conclusions: In the study there were male preponderance with 75.26% males and 57.39% females were having CD4 count less than350/cumm at the time of registration respectively. Majority of our study subjects were working at the time of start of ART. The deaths among males were significantly more as compared to females.

scholarly journals Delayed myocardial enhancement in children with different types of cardiomyopathy: a diagnostic and prognostic tool

2019 ◽  
Vol 50 (1) ◽  
Author(s):  
Hend Gamal Mohamed Fathy Abuo Elfadl ◽  
Sabry Alam El Dean Mohamed El Mogy ◽  
Mohamed Magdy Aly Abouelkeir ◽  
Ghada Mohamad Gaballah ◽  
Nevertiti Kamal El-Din Eid
Keyword(s):  
Adverse Effect ◽  
Late Gadolinium Enhancement ◽  
Imaging Modality ◽  
Cardiac Effect ◽  
Contrast Study ◽  
Gadolinium Enhancement ◽  
Non Invasive ◽  
Major Adverse Effect ◽  
Significant Difference ◽  
Different Types

Abstract Background The pattern of late gadolinium enhancement (LGE) in cardiomyopathy is quite different in children compared to adults. In addition, the data about LGE imaging in children are still restricted, so the goal was to study the role of cardiac magnetic resonance (CMR) with different techniques, including LGE images in diagnosis and evaluation of different types of cardiomyopathy in children. Results In group A (enhancement group), LVEDV 146.2 (144) ml, indexed LVEDV 81.8 (195) ml, LVESV 50 (357) ml, indexed LVESV 47.5 (243) ml, and LVEF 36% (64%), and a major adverse effect was found in 12 out of 15 cases (80%). However, in group B (non-enhancement group), the results were LVEDV 72 (303) ml, indexed LVEDV 75 (318) ml, LVESV 30 (220) ml, indexed LVESV 37.1 (189) ml, and LVEF 45.79% (65%), and a major adverse cardiac effect was found in 2 out of 16 cases (12.5%). The LVEF was lower, and LV volume indices including LVEDV and LVESV were higher in patients with LGE compared to those without LGE with a statistically significant difference (p value = 0.001, p value = 0.003, and p value = 0.005, respectively). Furthermore, it was also found that a major adverse effect occurs with higher incidence in enhancement cases (92%) as compared to non-enhancement cases (12.5%) with a statistically significant difference (p value ≤ 0.001). LGE was found in 15 cases out of 31 cases (48.4%); however, the remaining 13 cases had no contrast study. Conclusion Cardiac MRI can be considered as an important non-invasive imaging modality, not only for assessment but also for differentiation between ischemic and non-ischemic cardiomyopathy in the pediatric age group. Using its different techniques allows a better assessment of morphologic and functional parameters in cardiomyopathy. Moreover, the late gadolinium enhancement is regarded as a promising non-invasive tool in the detection and quantification of myocardial scars. That is considered of high importance in diagnosis, categorization, and detection of etiology in most cases of different types of cardiomyopathy, in addition to risk stratification that can be an essential step in patient management.

scholarly journals Correlation of Total Lymphocyte Count with CD4 Count in HIV/AIDS Patients

2015 ◽  
Vol 1 (1) ◽  
Author(s):  
Ardo Sanjaya ◽  
Christine Sugiarto ◽  
Ronald Jonathan
Keyword(s):  
Lymphocyte Count ◽  
Correlation Coefficients ◽  
Total Lymphocyte Count ◽  
Cd4 Count ◽  
Clinical Staging ◽  
Cross Sectional ◽  
Total Lymphocyte ◽  
Significant Difference ◽  
Clinical Stages ◽  
Hiv Aids

HIV infection is a chronic infection of the immune system with a target of CD4 cells. Total lymphocyte count (TLC) can be done in resource-limited areas and are able to be used as a substitute to CD4 count. An increase in CD8 count can disturb the correlation between CD4 and TLC especially during the late clinical stage.Objective of this research is to find out the correlation of total lymphocyte count with CD4 count and to find out the influence of the clinical staging on the correlation of total lymphocyte count and CD4 count.This study is an observational, analytical and cross sectional study using the medical records of Klinik Teratai RSHS Bandung. The data is sorted according to the WHO clinical staging and are analyzed using Pearson’s correlation and Fisher’s transformation with α=0.05. The results showed that TLC have a correlation with CD4 count in all stadiums (r: 0,501-0,684, p<0,01). There is no significant difference of the correlation coefficients between the clinical stages (p>0.05). There is a correlation between TLC and CD4 count on HIV infected patients and there is no significant decrease of correlation of TLC and CD4 count on HIV infected patients with worsening of the WHO clinical stages. Keywords: CD4 count, total lymphocyte count, HIV/AIDS

scholarly journals MR CHOLANGIO-PANCREATICOGRAPHY AS A TOOL FOR EVALUATION OF PATIENTS WITH PANCREATICOBILIARY DISEASES

2020 ◽  
Vol 8 (11) ◽  
pp. 901-951
Author(s):  
Ashraf S. Nadaf ◽  
◽  
Nanjaraj C.P ◽  
Rajendra Kumar N.L ◽  
Shashi Kumar M.R ◽  
...  
Keyword(s):  
Soft Tissues ◽  
Imaging Modality ◽  
Common Finding ◽  
Imaging Method ◽  
Biliary Disease ◽  
Diagnostic Modality ◽  
Medical College ◽  
Non Invasive ◽  
Adjacent Structures ◽  
Study Population

Objectives Of Study: 1. To describe features of pancreaticobiliary diseases on MRCP. 2. Outlining the extent in terms of involvement of adjacent structures, vessels
and soft tissues. 
 3. To help in deciding further course of management. 4. To identify the anatomical variants. 
 5. To prove the Magnetic Resonance Cholangio-Pancreatography (MRCP) is
one of the best imaging modality for evaluation of pancreatico-biliary disease. Material And Methods:The present study was undertaken to evaluate the role of MRCP in evaluation of pancreaticobiliary diseases. The study will be done on patients presenting with features suggestive of pancreatico-biliary diseases attending the OPD or admitted in various wards of Krishna Rajendra hospital, Mysore attached to Mysore Medical College & Research Institute, Mysore. A total of 30 patients were included in our study. Result:Majority of patients in study population were males (60%) while 40% were females. The mean age of the study sample was 37.5 years and maximum numbers of cases were observed in age group of > 40 years. Majority of pathologies observed were benign 18(60%). Pancreatitis was the most common finding (33.3%) followed by Cholangiocarcinoma (20%), Choledocholithiasis (13.4%), Periampullary carcinoma (10%), Ca. Pancreas (6.7%) & Choledochal cyst (6.7%).Pancreatitis is common in males followed by Cholangiocarcinoma, which is common in both males & females.Both benign & malignant strictures have equal predominance. Both benign & malignant strictures are common in proximal CBD. Conclusion: MRCP is non-invasive, non-ionizing imaging method for evaluation of pancreatico-biliary anatomy and pathology. It is superior diagnostic modality in detection and characterization of pancreatico-biliary pathologies.

Effect of AerobicandProgressive Resistance Training on Functional Capacity, Quality of Life and CD4 Count in People with HIV/AIDS

2012 ◽  
Vol 3 (7) ◽  
pp. 226-231 ◽  
Author(s):  
Vaiyapuri Anandh ◽  
◽  
Ivor Peter D’SA Ivor Peter D’SA ◽  
Jagatheesan Alagesan
Keyword(s):  
Quality Of Life ◽  
Resistance Training ◽  
Functional Capacity ◽  
Cd4 Count ◽  
Hiv Aids

HIV/AIDS Awareness and Knowledge in Rural Adolescent: A Cross-sectional survey in Central India

2012 ◽  
Vol 3 (5) ◽  
pp. 1-3
Author(s):  
* Avinash Borkar ◽  
◽  
Namita Deshmukh ◽  
Deepak Lone ◽  
Mohan Khamgaonkar
Keyword(s):  
Central India ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Aids Awareness ◽  
Rural Adolescent ◽  
Hiv Aids

A novel use of contrast-enhanced ultrasound in uterine artery embolization

2020 ◽  
Vol 4 ◽  
pp. 8
Author(s):  
Jemianne Bautista Jia ◽  
Eric Mastrolonardo ◽  
Mateen Soleman ◽  
Ilya Lekht
Keyword(s):  
Uterine Artery Embolization ◽  
Uterine Artery ◽  
Imaging Modality ◽  
Cost Effective ◽  
Contrast Enhanced Ultrasound ◽  
Artery Embolization ◽  
Non Invasive ◽  
Contrast Enhanced

Contrast-enhanced ultrasound (CEUS) is a cost-effective, quick, and non-invasive imaging modality that has yet to be incorporated in uterine artery embolization (UAE). We present two cases that demonstrate the utility of CEUS in UAE for the identification of uterine-ovarian collaterals which otherwise can result in ineffective fibroid treatment and non-target embolization.

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