scholarly journals Aerobic bacterial profile and their antimicrobial sensitivity pattern in patients of otitis media with ear discharge

2021 ◽  
Vol 9 (12) ◽  
pp. 3602
Author(s):  
Jagannath Babu G.R. ◽  
Kavya S. ◽  
Anuradha K.
Keyword(s):  
Otitis Media ◽  
Descriptive Statistics ◽  
Drug Resistant ◽  
Upper Respiratory Tract ◽  
First Line ◽  
Suppurative Otitis Media ◽  
Antimicrobial Sensitivity ◽  
Sensitivity Pattern ◽  
Upper Respiratory ◽  
And Staphylococcus Aureus

Background: The average prevalence of Chronic suppurative otitis media (CSOM) in India is 5.2%. It is more prevalent due to various predisposing factors such as malnutrition, overcrowding, poor hygiene, inadequate health care, and recurrent upper respiratory tract infection. In recent years, there is increased preponderance of multi drug resistant organisms due to the irrational use of antibiotics, making treatment of CSOM more difficult.Methods: Samples from 100 subjects of uncomplicated CSOM who presented to the Oto-Rhino-Laryngology outpatient department of our hospital were collected. Aerobic bacterial profile and its Antimicrobial susceptibility were studied by conventional methods. Results were compiled and evaluated by descriptive statistics and inferential statistics.Results: Pseudomonas aeruginosa (50.7%) and Staphylococcus aureus (19.04%) were the predominant isolates in our study. Aminoglycosides and Fluoroquinolones were found to be effective first line drugs, followed by Carbapenems.Conclusions: These antibiotics can be used to prevent the life-long complications of CSOM. Timely culture and sensitivity helps in the management of these cases. 

scholarly journals Prevalence and Risk Factors of Chronic Suppurative Otitis Media in a Teaching Hospital, Telangana

2021 ◽  
Vol 8 (20) ◽  
pp. 1495-1499
Author(s):  
Shyam G ◽  
Rachana G ◽  
Mohammed Yawar
Keyword(s):  
Risk Factors ◽  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Otitis Media ◽  
Chronic Suppurative Otitis Media ◽  
Age Group ◽  
Upper Respiratory Tract ◽  
Suppurative Otitis Media ◽  
Upper Respiratory

BACKGROUND Chronic suppurative otitis media (CSOM) is defined as a chronic inflammation of the middle ear and mastoid cavity. The disease usually begins in childhood. We need to study the prevalence and risk factors of chronic suppurative otitis media in a teaching hospital in Telangana. METHODS This was a cross sectional study done among patients with CSOM attending the Department of ENT for a duration of one year from January 2019 to December 2019. Detailed history, otoscopic examination and culture sensitivity tests of ear discharge were done. RESULTS The sample size was 150. The prevalence of CSOM was reported to be 7.5 %. Majority of the cases were in the 11 - 15 years age group, i.e., 56.6 %. Tubotympanic type was most commonly reported and accounted for 80 % (100 / 150) whereas atticoantral type was 20 %. Pseudomonas aeruginosa was the most commonly isolated organism from the ear discharge. Most of the CSOM cases presented with upper respiratory tract infection i.e., 20 %. CONCLUSIONS The prevalence of CSOM in our study was 7.5 % and it was more common in the younger age group. CSOM was more common in the lower socioeconomic class. Upper respiratory tract infection is a frequent mode of presentation of CSOM. KEYWORDS CSOM, Ear Discharge, Tubotympanic CSOM, Atticoantral CSOM

scholarly journals Antimicrobial Susceptibility Pattern of Bacterial Isolates from Patients with Chronic Suppurative Otitis Media

2020 ◽  
Vol 22 (2) ◽  
pp. 90-95
Author(s):  
Salah Uddin Ahmmed ◽  
AKM Asaduzzaman ◽  
Basir Ahmed ◽  
Monsur Alam ◽  
Misbah AL Kabir ◽  
...  
Keyword(s):  
Otitis Media ◽  
Antimicrobial Susceptibility ◽  
Chronic Suppurative Otitis Media ◽  
Diffusion Method ◽  
Bacterial Isolates ◽  
Suppurative Otitis Media ◽  
Antimicrobial Susceptibility Pattern ◽  
Antimicrobial Sensitivity ◽  
Sensitivity Pattern ◽  
High Level

Background: Chronic suppurative otitis media (CSOM) is one of the common diseases of the middle ear especially in developing countries. Early and effective treatment based on the knowledge of causative micro-organisms and their antimicrobial sensitivity pattern ensures prompt clinical recovery and possible complications may be avoided. Objectives: This study was done to determine the pattern of bacterial isolates and to detect their antibiogram. Methods: A total of 103 patients clinically diagnosed of CSOM were enrolled in the study and the samples were obtained from each patient using sterile cotton swabs and cultured for bacterial isolates. Antimicrobial susceptibility test of the isolates were performed using Kirby- Bauer disc diffusion method. Results: Among the cases females were more affected than males. Out of the 103 cases, bacteriological investigation revealed that Pseudomonas aeruginosa 42 (44.68%) and Staphylococcus aureus 31(32.97%) were the predominant bacteria. Ciprofloxacin and Ceftazidime revealed high level of sensitivity whereas high resistance rates were observed for Amoxycillin, Gentamicin and Cephalexin. Conclusion: The study concluded that an appropriate knowledge of the etiological agents and antibacterial susceptibility of microorganisms would contribute to a rational use of antibiotics, success of treatment and reduce the complications of CSOM. Bangladesh J Otorhinolaryngol; October 2016; 22(2): 90-95.

scholarly journals Clinico-epidemiological profile of chronic otitis media at a tertiary care hospital

2020 ◽  
Vol 6 (12) ◽  
pp. 2222
Author(s):  
Hubballi Ravi Kishore ◽  
Reshma P. R.
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Otitis Media ◽  
Chronic Otitis Media ◽  
Upper Respiratory Tract Infection ◽  
Care Hospital ◽  
Upper Respiratory Tract ◽  
Suppurative Otitis Media ◽  
Upper Respiratory

<p><strong>Background:</strong> Chronic otitis media equates with the term chronic suppurative otitis media that is no longer advocated as it is not necessarily a result of the gathering of pus. Incidence of this disease is higher in developing countries especially among lower socioeconomic society because of malnutrition, overcrowding, poor hygiene, inadequate health care facility and recurrent upper respiratory tract infection.</p><p><strong>Methods: </strong>Eighty patients with chronic otitis media were included. After obtaining written and informed consent, they were subjected to detailed history taking and examination. Various risk factors of chronic otitis media and the morbidity caused by the disease were studied. Data was analyzed using IBM SPSS version 22.<strong></strong></p><p><strong>Results: </strong>The most common age group was 21-30 years with male predominance. Central perforation was the most common type of perforation. Various factors like low socioeconomic status, rural setup, overcrowding, malnutrition, indoor cooking, recurrent acute otitis media, recurrent upper respiratory tract infection, naso-respiratory allergies, habit of swimming, taking bath in pond, ear probing were found to cause the onset of the disease and worsen of the disease process.<strong></strong></p><p><strong>Conclusions: </strong>Chronic otitis media results in various morbidity including increased financial burden, restricts daily activities, hence affects the psychological mindset and lowers the confidence of the patient giving them a feeling of social outcast. A proper awareness must be spread regarding these factors, maintaining personal hygiene, improving nutrition and immunity. An immediate consultation with the otorhinolaryngologist will reduce the disease progression and hence the complications. <strong></strong></p>

scholarly journals Upper Respiratory Tract Microbiome and Otitis Media Intertalk: Lessons from the Literature

2020 ◽  
Vol 9 (9) ◽  
pp. 2845
Author(s):  
Francesco Folino ◽  
Luca Ruggiero ◽  
Pasquale Capaccio ◽  
Ilaria Coro ◽  
Stefano Aliberti ◽  
...  
Keyword(s):  
Respiratory Tract ◽  
Otitis Media ◽  
Middle Ear ◽  
Bacterial Communities ◽  
Acute Otitis Media ◽  
Upper Respiratory Tract ◽  
Suppurative Otitis Media ◽  
Major Interest ◽  
Culture Independent ◽  
Upper Respiratory

Otitis media (OM) is one of the most common diseases occurring during childhood. Microbiological investigations concerning this topic have been primarily focused on the four classical otopathogens (Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and Streptococcus pyogenes) mainly because most of the studies have been conducted with culture-dependent methods. In recent years, the introduction of culture-independent techniques has allowed high-throughput investigation of entire bacterial communities, leading to a better comprehension of the role of resident flora in health and disease. The upper respiratory tract (URT) is a region of major interest in otitis media pathogenesis, as it could serve as a source of pathogens for the middle ear (ME). Studies conducted with culture-independent methods in the URT and ME have provided novel insights on the pathogenesis of middle ear diseases through the identification of both possible new causative agents and of potential protective bacteria, showing that imbalances in bacterial communities could influence the natural history of otitis media in children. The aim of this review is to examine available evidence in microbiome research and otitis media in the pediatric age, with a focus on its different phenotypes: acute otitis media, otitis media with effusion and chronic suppurative otitis media.

scholarly journals Evaluation of antimicrobial sensitivity pattern of chronic suppurative otitis media in a tertiary care hospital of West Bengal, India

2017 ◽  
Vol 6 (4) ◽  
pp. 891
Author(s):  
Shirsendu Mondal ◽  
Manasi Banerjee ◽  
Sudip Das
Keyword(s):  
Staphylococcus Aureus ◽  
Otitis Media ◽  
West Bengal ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Chronic Suppurative Otitis Media ◽  
Care Hospital ◽  
Suppurative Otitis Media ◽  
Antimicrobial Sensitivity ◽  
Sensitivity Pattern

Background: Chronic suppurative otitis media is a common infectious disease in our country. The micro-organisms commonly causing the disease and their antibiotic sensitivity pattern is important for treatment. This study was conducted to evaluate the antimicrobial sensitivity pattern of the common microorganisms in patients with chronic suppurative otitis media in our tertiary care hospital.Methods: The study was carried out from July 2013 to December 2013 at the ENT out-patient department of a tertiary care hospital in West Bengal. 100 patients aged 18 to 60 years of either sex, with unilateral or bilateral active chronic suppurative otitis media attending the out- patient clinic were included in the study. Pus samples were collected from the discharging ears and sent for isolating the organisms and susceptibility testing.Results: A total number of 108 ear swabs were collected from the 100 recruited patients of which 15 (13.88%) were sterile and 93 (86.11%) showed presence of organisms. Pseudomonas aeruginosa 41(38%) was the commonest organism isolated, followed by Staphylococcus aureus 25(23.15%). The antimicrobial profile of the microorganisms reveals maximum sensitivity of the isolated organisms to piperacillin and levofloxacin.Conclusions: In our study, Pseudomonas aeruginosa (38%) and Staphylococcus aureus (23.15%) are the major pathogens involved in the etiology of CSOM. The isolates showed maximum sensitivity to piperacillin (41%) and levofloxacin (41%). As piperacillin is available only in parenteral form and is also costly, topical levofloxacin can be recommended in empirical treatment of CSOM.

scholarly journals A prospective study on pattern of microbes in chronic suppurative otitis media

2021 ◽  
Vol 7 (2) ◽  
pp. 331
Author(s):  
Ajaz U. Haq ◽  
Rishabh Dogra ◽  
Kanika Arora ◽  
Fatma Anjum
Keyword(s):  
Otitis Media ◽  
Antibiotic Sensitivity ◽  
Local Area ◽  
Multidrug Resistant ◽  
Maximum Activity ◽  
Chronic Suppurative Otitis Media ◽  
Suppurative Otitis Media ◽  
Microbial Profile ◽  
Antimicrobial Sensitivity ◽  
Sensitivity Pattern

<p class="abstract"><strong>Background:</strong> Chronic suppurative otitis media (CSOM) is a common chronic ear disease causing serious local damage and complications. Irrational use of antibiotics for its management has led to the emergence of multidrug-resistant strains. This study was conducted to find out the microbial profile and their antimicrobial sensitivity patterns in CSOM patients in Garhwal belt.</p><p class="abstract"><strong>Methods:</strong> A total number of 100 patients of clinically diagnosed CSOM were enrolled over the duration of 1 year. Ear discharge was collected using sterile swabs and processed for the identification of aerobes, anaerobes and fungal isolates. Antimicrobial susceptibility testing of the isolates was performed.  </p><p class="abstract"><strong>Results:</strong> Maximum incidence of CSOM was observed in patients of 10–20 years age group with female preponderance. Decreased hearing was the main associated symptom. Out of 100 swabs, microbial growth was obtained in 88 samples amongst which 61 had monomicrobial growth while 39 had polymicrobial growth. Pseudomonas aeruginosa was the most common isolate. Amikacin showed maximum activity to most of the isolates.</p><p class="abstract"><strong>Conclusions:</strong> Evaluation of microbes and their antibiotic sensitivity pattern in local area becomes helpful in prescribing empirical treatment for successful cure of CSOM.</p>

scholarly journals OTITIS MEDIA;

2019 ◽  
Vol 26 (02) ◽  
Author(s):  
S.M Abbas Naqvi ◽  
Rubina Yaseen ◽  
Zulfiqar Ali Naqvi
Keyword(s):  
Otitis Media ◽  
Cross Sectional Study ◽  
Chronic Suppurative Otitis Media ◽  
Cross Sectional ◽  
Suppurative Otitis Media ◽  
Media Study ◽  
Antimicrobial Sensitivity ◽  
Sensitivity Pattern ◽  
Causative Agents ◽  
Medical University

… Background and Objectives: The objective of this study is to determine pattern of bacterial isolates and their antimicrobial sensitivity pattern among patients with chronic suppurative otitis media. Study Design: Prospective study (descriptive cross-sectional study). Setting: Department of ENT and Microbiology, Nishtar Medical University and Hospital Multan. Period: June 2014 to December 2014. Material and Methods: A total of 50 patients presenting with chronic suppurative otitis media having unilateral or bilateral ear discharge were enrolled from OPD of ENT department of Nishtar Hospital. Results: Of these 50 patients with CSOM, 22 (44%) were male patients while 28 (56%) were female patients. Mean age of our study cases was noted to be 12.52 ± 11.53 years (ranging from 5 years to 52 years). Most burden of the disease was seen in children i.e. 25 (50%) of the patients were less than 10 years of age. During the whole study unilateral discharge was seen and table 1 shows 50 specimens of CSOM were investigated for bacterial infestation and found to be infected with different bacteria. the highest number of cases were infected with s. aureus 24 (48 %) followed by 11 pseudomonas aeruginosa (22 %), 11 proteus mirabilis (22%) and 3 E. coli (6%) patients. Conclusions: Due to variation in climate, community, accessibility of medical care and prescription of antibiotics, the pattern vary in CSOM patients. Therefore it is very important to identify the causative agents of CSOM and their sensitivity pattern against various antibiotics before treatment of the disease in the patients.

scholarly journals Toll-Like Receptors: Expression and Roles in Otitis Media

2021 ◽  
Vol 22 (15) ◽  
pp. 7868
Author(s):  
Su Young Jung ◽  
Dokyoung Kim ◽  
Dong Choon Park ◽  
Sung Soo Kim ◽  
Tong In Oh ◽  
...  
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Otitis Media ◽  
Middle Ear ◽  
Upper Respiratory Tract Infection ◽  
Upper Respiratory Tract ◽  
Toll Like Receptors ◽  
Upper Respiratory

Otitis media is mainly caused by upper respiratory tract infection and eustachian tube dysfunction. If external upper respiratory tract infection is not detected early in the middle ear, or an appropriate immune response does not occur, otitis media can become a chronic state or complications may occur. Therefore, given the important role of Toll-like receptors (TLRs) in the early response to external antigens, we surveyed the role of TLRs in otitis media. To summarize the role of TLR in otitis media, we reviewed articles on the expression of TLRs in acute otitis media (AOM), otitis media with effusion (OME), chronic otitis media (COM) with cholesteatoma, and COM without cholesteatoma. Many studies showed that TLRs 1–10 are expressed in AOM, OME, COM with cholesteatoma, and COM without cholesteatoma. TLR expression in the normal middle ear mucosa is absent or weak, but is increased in inflammatory fluid of AOM, effusion of OME, and granulation tissue and cholesteatoma of COM. In addition, TLRs show increased or decreased expression depending on the presence or absence of bacteria, recurrence of disease, tissue type, and repeated surgery. In conclusion, expression of TLRs is associated with otitis media. Inappropriate TLR expression, or delayed or absent induction, are associated with the occurrence, recurrence, chronicization, and complications of otitis media. Therefore, TLRs are very important in otitis media and closely related to its etiology.

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