scholarly journals A study of correlation of pulmonary function test in patients with metabolic syndrome with different components of metabolic syndrome

2022 ◽  
Author(s):  
Prabhu S. ◽  
Sudha Karbari
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Pulmonary Function ◽  
Pulmonary Function Tests ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Forced Expiratory Volume ◽  
Cross Sectional ◽  
Increased Risk ◽  
The Social

Background: The increasing incidence of metabolic syndrome has been on the rise especially in urban population and leading to increased risk of cardiovascular disease (CVD) and diabetes mellitus. It has been associated with impairment of pulmonary functions. However, there is limited data regarding the association with individual components of metabolic syndrome and overall effect on components of pulmonary functions.Methods: This is a cross sectional study consisting of 50 subjects with metabolic syndrome. All the subjects underwent pulmonary function tests and the association between different components of metabolic syndrome and pulmonary function were examined using unpaired t-test and Pearson’s partial correlation coefficient. This data was analysed by using statistical package for the social sciences (SPSS) version 12.0.Results: In females, moderate negative significant correlation was seen between forced vital capacity (FVC) and systolic blood pressure (SBP), diastolic blood pressure (DBP), fasting blood sugar (FBS), triglyceride (TG), waist circumference (WC) and body mass index (BMI) whereas positive weak non-significant correlation was seen between FVC and high density lipoprotein cholesterol (HDLC), while no such relation was found with forced expiratory volume in one second (FEV1). In males, negative, moderate significant correlation was seen between FVC and FBS whereas strong, positive, significant correlation was seen between FVC and WC; between FVC and BMI. Negative, moderate, significant correlation was seen between FEV1 and WC; between FEV1 and BMI.Conclusions: Our study concluded that there was a significant impact of FBS and WC on decreasing FVC on both genders with minimally significant impact of other components of metabolic syndrome on FVC with no effect on FEV1 hence indicating a restrictive pattern of pulmonary function derangement. Hence, further studies with larger sample size is needed to confirm whether there are direct or indirect mechanisms through which insulin resistance could affect pulmonary function.

scholarly journals Prevalence of Metabolic Syndrome in Women With Polycystic Ovarian Diseases in a Outdoor Setting

2013 ◽  
Vol 23 (2) ◽  
pp. 18-21
Author(s):  
Shahanara Chowdhury ◽  
Afroza Ferdous
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Serum Prolactin ◽  
Obese Women ◽  
Cross Sectional ◽  
Outdoor Setting ◽  
Increased Risk ◽  
Ovarian Diseases

Polycystic ovarian diseases (PCOD) is a condition associated with chronic anovulation, insulin resistance and androgen access. Women with this syndrome are at increased risk of metabolic syndrome. The aim of the present study was to determine the prevalence of metabolic syndrome (MBS) in women with PCOD in a private outdoor setting in different ages and body mass index (BMI). A cross sectional study was conducted in a private clinic setting. A total of 146 women with PCOD ages between 15-40 years included. The prevalence of metabolic syndrome and its components in these population were the outcomes. Height, weight, waist circumference, blood pressure and the laboratory tests (FBS,TSH,HDLC, serum prolactin, triglycerides and total cholesterol) were measured in this population. The prevalence of MBS in PCOD women was 24% (36 cases). The rate of central obesity, FBS more than 110 mg/dl, triglycerides more than 150 mg/dl, high-density lipoprotein cholesterol levels (HDL-C) less than 50 mg/dl, and blood pressure 130/85 mmHg in PCOD women was 29.45% (43), 4.10% (6), 34.93% (51), 66.43% (97), and 10.27% (15), respectively. The risk of MBS was increased in older and the obese women (BMI 30 kg/m2). The present study showed that women with PCOD have high prevalence of MBS & its individual components, particularly decreased HDL-C. JCMCTA 2012 ; 23 (2): 18-21

scholarly journals Association of breastfeeding and risk of metabolic syndrome and its components in postmenopausal parous women: Korea national health and nutrition examination survey (2010 ~ 2016)

2021 ◽  
Vol 79 (1) ◽  
Author(s):  
Jusuk Lee ◽  
Taehong Kim
Keyword(s):  
Metabolic Syndrome ◽  
Laboratory Data ◽  
Multivariate Logistic Regression Analysis ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Korean Women ◽  
Cross Sectional ◽  
Increased Risk ◽  
Nationally Representative ◽  
Study Participants

Abstract Background Understanding the relationship between breastfeeding (BF) and metabolic syndrome (Mets) is important for maternal long-term health benefits and disease prevention. This study aimed to examine the association between BF and Mets and its components among postmenopausal parous Korean women. Methods This cross-sectional study on 10,356 Korean women used nationally representative data from the KNHANES from 2010 to 2016. Anthropometric, laboratory data and manual BP were measured. A multivariate logistic regression analysis was conducted to examine the association of BF with Mets and its components after adjusting for potential confounding variables. A p-value < 0.05 was to be considered statistically significant. Results Mets was present in 42% of the study participants. The BF group had low household income and education level. The prevalence of Mets in the BF group was higher than that in the non-BF group (42.69% vs. 34.76%, p <  0.001). BF was associated with increased risk of Mets (odds ratio [OR]: 1.4, 95% confidence interval [CI]: 1.18–1.65, p <  0.001). The BF group was at higher risks for diabetes (OR: 1.5, 95%CI: 1.14–1.98), hypertension (OR: 1.32, 95%CI: 1.03–1.68), hypertriglyceridemia (OR: 1.42, 95%CI: 1.02–1.99) and low high-density lipoprotein cholesterol (OR: 1.32, 95%CI: 1.06–1.65). Conclusion In this study, BF did not affect decreasing the prevalence of Mets and its components.

Melatonin and cryptochrome 2 in metabolic syndrome patients with or without diabetes: a cross-sectional study

2018 ◽  
Vol 35 (2) ◽  
Author(s):  
Ibrahim Abdul Kareem Al-Sarraf ◽  
Violet Kasabri ◽  
Amal Akour ◽  
Randa Naffa
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Overweight And Obesity ◽  
P Value ◽  
Metabolic Risk ◽  
Sectional Study ◽  
Cross Sectional ◽  
Cryptochrome 2

Abstract Background Metabolic syndrome (MetS) is a cluster of metabolic risk factors which increases the chances for future cardiovascular diseases, as well as diabetes. The underlying causes of MetS include overweight and obesity, physical inactivity and genetic factors. Our intension here was to focus in this study on the importance of the chronobiology, represented by melatonin (MT) and cryptochrome 2 (CRY2), in developing MetS and type 2 diabetes mellitus (T2DM). Thus, we aimed to compare MT and CRY2 plasma levels and correlate both biomarkers with adiposity, atherogenicity and hematological indices in MetS and T2DM cohorts. Methods In a cross-sectional study, 28 normoglycemic lean subjects (controls), 29 normoglycemic MetS subjects and 30 MetS (pre-diabetic/diabetic) were recruited. Results MT (pg/mL) was elevated significantly in MetS arm p-value < 0.05, whereas CRY2 levels (ng/mL) were markedly higher in both MetS groups (non-diabetic and pre-diabetic/diabetic) (all with p-value < 0.001). A reciprocal MT-CRY2 relationship was observed in the MetS (non-diabetic) group (p-value = 0.003). Of note in the total study population, both MT and CRY2 proportionally correlated with each of the following: atherogenicity index of plasma (AIP), waist circumference (WC) and systolic blood pressure (SBP) (all with p-value < 0.05) for MT and CRY2, respectively). Whereas MT correlated inversely with high-density lipoprotein-cholesterol (HDL-C) (p-value < 0.05). Additionally, CRY2 correlated directly with each of the following: diastolic blood pressure (DBP), total cholesterol (TC), low-density lipoprotein (LDL-C), hip circumference (HC), body adiposity index (BAI), weight-to-height (WHtR) ratio, mean platelet volume (MPV) and platelet/lymphocyte ratio (PLR) (p-value < 0.05). Conclusion These findings substantiate that both metabolic risk biomarkers can be prognostic tools and pharmacotherapeutic targets to slowdown the accelerated nature of T2DM.

scholarly journals C-Peptide Versus Insulin: Relationships with Risk Biomarkers of Cardiovascular Disease in Metabolic Syndrome in Young Arab Females

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
A. Abdullah ◽  
H. Hasan ◽  
V. Raigangar ◽  
W. Bani-Issa
Keyword(s):  
Blood Pressure ◽  
Cardiovascular Disease ◽  
Metabolic Syndrome ◽  
Density Lipoprotein ◽  
High Sensitivity ◽  
Cross Sectional Study ◽  
Normal Weight ◽  
Health Concern ◽  
Cross Sectional ◽  
C Peptide

Background. Obesity is a major health concern and is associated with metabolic syndrome (MetS) that increases the risk for cardiovascular disease (CVD). Since little is known about the relationships between MetS components and CVD in overweight/obese young Arab females, our study aimed at examining these relationships and further to explore the associations between connecting peptide (C-peptide) and insulin with these biomarkers.Subjects and Methods. In this cross-sectional study, 80 apparently healthy young Arab females were recruited and grouped by their body mass index (BMI) into normal-weight (GI) and overweight/obese (GII) groups.Results. The two groups significantly differed in BMI, waist circumference (WC) and values of biomarkers, namely, leptin, fasting insulin, uric acid (UA), insulin resistance (HOMA-IR), C-peptide, high-sensitivity C-reactive protein (hs-CRP), high-density lipoprotein cholesterol (HDL-C), systolic blood pressure (SBP), and diastolic blood pressure (DBP). C-peptide significantly correlated with WC, leptin, UA, and HDL-C and was predicted by three biomarkers; UA, WC and HDL-C. Whereas, insulin significantly correlated with only two biomarkers including leptin and DBP and was predicted by UA and DBP.Conclusions. The present study highlighted the association between MetS and CVD in young Arab females and the possible role of C-peptide in the prediction of CVD.

scholarly journals Effects of metabolic syndrome on pulmonary function tests

2021 ◽  
Author(s):  
Sidhant Sachdeva ◽  
Gurinder Mohan ◽  
Sunil Grover ◽  
Shashi Mahajan
Keyword(s):  
Metabolic Syndrome ◽  
Pulmonary Function ◽  
Pulmonary Function Tests ◽  
Density Lipoprotein ◽  
Mean Value ◽  
High Serum ◽  
Serum Triglycerides ◽  
Cross Sectional ◽  
Number Of Components ◽  
Restrictive Pattern

Background: Metabolic syndrome is defined as at least three of the five following medical conditions: central obesity(mandatory), high blood pressure, high blood sugar, high serum triglycerides, and low serum high-density lipoprotein (HDL). It has been shown that obesity causes physiological impairment in respiratory system.Methods: In this observational cross sectional study, 60 patients who fulfilled the IDF criteria for metabolic syndrome were included after applying the exclusion criteria and were subjected to spirometry.Results: Most of the patients had a restrictive pattern (43.3%) (n=26). 33.3% (n=20) of the patients had a mixed pattern while 16.7% (n=10) of the patients had a normal picture. Only 6.7% (n=4) of the patients had an obstructive pattern (p<0.001). Mean value of FEV1 had no correlation with increasing number of components of metabolic syndrome whereas mean value of FVC showed a decreasing trend with increasing number of components of metabolic syndrome. Mean FEV1 of the patients was significantly higher in males (1.82±0.71 L) than females (1.24±0.42 L) (p 0.007). Similarly, the mean FVC was significantly higher in males as compared to females. Mean FVC was 2.45 (±0.86) L in males while females had a mean FVC of 1.65 (±0.49) L (p 0.002).Conclusions: In conclusion, Patients with metabolic syndrome have significant impairment of the pulmonary function with restrictive pattern being the most common one.

scholarly journals Metabolic Syndrome in Bangladeshi Menopausal Women

2016 ◽  
Vol 34 (1) ◽  
pp. 15-20 ◽  
Author(s):  
Muna Shalima Jahan ◽  
Syed Muhammad Baqui Billah
Keyword(s):  
Metabolic Syndrome ◽  
Rural Area ◽  
Density Lipoprotein ◽  
Hdl Cholesterol ◽  
Cross Sectional Study ◽  
Blood Analysis ◽  
Cross Sectional ◽  
Increased Risk ◽  
Menopausal Women ◽  
Post Menopausal

Objective: To assess the factors of metabolic syndrome (MetS) in post menopausal women in Bangladesh.Methods: Menopausal women are at increased risk of metabolic syndrome (MetS). This cross-sectional study on 64 willing post menopausal women from an urban and a rural area of Bangladesh was done. The socio-epidemiologic factors with anthropometric examination, blood pressure recording and fasting blood analysis for triglyceride (TG), high density lipoprotein (HDL), sugar were studied.Results: Prevalence of MetS was 50.0% (95% CI= 39.9%- 60.1%) among menopausal women, seventy five percent of them were urban. Low HDL cholesterol prevailed in almost 96% respondents followed by high TG (51%), obesity (28.0%), high fasting blood sugar (FBS, 27.1%) and hypertension (HTN, 16.9%). On logistic regression, age (OR=1.6, 95% CI: 1.3-1. 9), male sex (OR=2.5, 95% CI: 1.4-4.2) and exercise (OR=1.9, 95% CI: 1.2-2.9) produced significantly higher odds of being associated with MetS; rural area (OR=1.4, 95% CI: 1.0-2.1) and sedentary occupation (OR=1.7, 95% CI: 0.9-3.0) were associated just insignificantly. Though higher income, better education, good physical movement and knowledge of MetS produced protective odds, they were not significant.Conclusions: The study suggests that MetS is highly prevalent among Bangladeshi menopausal women. Further studies are needed to identify risk factors and for effective preventive measures to control this metabolic disease.J Bangladesh Coll Phys Surg 2016; 34(1): 15-20

scholarly journals Risk of Cardiovascular Disease Related to Metabolic Syndrome in College Students: A Cross-Sectional Secondary Data Analysis

2019 ◽  
Vol 16 (19) ◽  
pp. 3708 ◽  
Author(s):  
Jang ◽  
Kim
Keyword(s):  
College Students ◽  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Cardiovascular Diseases ◽  
Density Lipoprotein ◽  
Secondary Data ◽  
Cross Sectional Study ◽  
Female Students ◽  
Clinical Variable ◽  
Cross Sectional

Early detection of metabolic syndrome (MS) in young adults can lead to decreased aggravation and help prevent diabetes and cardiovascular diseases. This cross-sectional study aimed to identify the prevalence of MS and its components in Korean college students and was based on the Korean National Health and Nutrition Examination Survey, which used a stratified multistage probability sampling design. In total, 6.5% male and 4.1% female students had MS; of these, 26.6% of male and 25.8% of female students presented with at least one MS component. Height, weight, body mass index (BMI), waist circumference (WC), systolic blood pressure (SBP), diastolic blood pressure (DBP), glucose, high-density lipoprotein cholesterol, and triglycerides were significantly higher in men than in women, and all of these variables showed significant differences according to BMI. As the BMI increased, the level of each anthropometric, biochemical, and clinical variable increased. Although only a few students in Korea had three or more risk factors, the proportion of college students with one risk factor for MS was relatively high. Therefore, educational and intervention programs should be conducted in college students with overweight or obesity so that they can change their lifestyle to reduce the risk of cardiovascular diseases and diabetes.

Metabolic Syndrome, and Not Obesity, Is Associated with Chronic Kidney Disease

2021 ◽  
Vol 52 (8) ◽  
pp. 666-672
Author(s):  
Stefano Ciardullo ◽  
Cinzia Ballabeni ◽  
Roberto Trevisan ◽  
Gianluca Perseghin
Keyword(s):  
Metabolic Syndrome ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Elevated Blood ◽  
Sectional Study ◽  
Cross Sectional ◽  
Urine Albumin ◽  
Increased Risk

<b><i>Introduction:</i></b> Obese (OB) patients are at increased risk of chronic kidney disease, but it is still unclear whether this can be attributed to obesity per se or to the associated metabolic derangements. The aim of this study was to evaluate the relative impact of obesity and metabolic syndrome (MS) on kidney disease. <b><i>Methods:</i></b> This is a cross-sectional study based on data obtained in the 2005–2016 cycles of the National Health and Nutrition Examination Survey. We included all adult participants with available data on body mass index, estimated glomerular filtration rate (eGFR), urine albumin to creatinine ratio (UACR), and each of the MS components. Primary outcomes were eGFR &#x3c;60 mL/min, UACR ≥30 mg/g, or a combination of the two. <b><i>Results:</i></b> The studied population comprised 12,335 participants. OB participants without MS (OB+ MS−) were younger and more commonly female. After adjustment for potential confounders, compared with OB− MS− participants, an increased prevalence of albuminuria and reduced eGFR were present in both OB− MS+ groups and the OB+ MS+ groups, but not in the OB+ MS− groups. When each of the MS components was evaluated separately, elevated blood pressure and low high-density lipoprotein cholesterol were associated with both UACR and reduced eGFR, while elevated blood glucose and triglycerides were only associated with UACR. Waist circumference was not associated with any of the renal outcomes. <b><i>Discussion/Conclusion:</i></b> This large cross-sectional study suggests that MS and not obesity is associated with kidney damage and that the OB+ MS− phenotype does not seem to carry an increased risk of kidney disease.

scholarly journals Comparison of metabolic syndrome criteria in obese and overweight children

2010 ◽  
Vol 50 (5) ◽  
pp. 295 ◽  
Author(s):  
Astrid Anastasia Malonda ◽  
Helena Anneke Tangkilisan
Keyword(s):  
Blood Pressure ◽  
Metabolic Syndrome ◽  
Waist Circumference ◽  
Density Lipoprotein ◽  
Cross Sectional Study ◽  
Overweight Child ◽  
Test Results ◽  
Overweight Children ◽  
Obese Children ◽  
Cross Sectional

Background Metabolic syndrome (MS) is a group of disorders which occur in relation to increasing body weight. Only a few studies have reported the differences in the fulfillment of MS criteria between obese and overweight children, and none were from Indonesia.Objective To detennine the differences in metabolic syndrome disorders between obese and overweight children.Methods A cross-sectional study was conducted in Manado from May to August 2010. The diagnosis of MS is established by fulfilling three of five criteria: waist circumference  ≥90th percentile, blood pressure ≥ 90th  percentile, fasting blood sugar (FBS) ≥ 100 mg/dL, triglycerides  ≥110 mg/dL and high density lipoprotein (HDL) ≤40 mg/dL. Obesity was defined as body mass index (BMI) of> 3 SD and overweight as BMI of 2-3 SD. Results Results ere analyzed by x2 and t-test. Results Thirty obese and 30 overweight children aged 10-14years were examined for the disorders of MS. Twenty􀁄three obese and 4 overweight children had waist circumferences  ≥90th percentile. Seventeen obese and 3 overweight children had blood pressure  ≥90th percentile. No significant differences in FBS, HDL, and triglycerides were observed between the two groups. Thirteen obese children met the MS inclusion criteria, while only 1 overweight child did so (P<0.001).Conclusions High blood pressure (≥90th percentile) and waist circumference (≥90th  percentile) occurred were observed at higher frequency in obese children than in overweight children. The occurrence of MS in obese children was significantly higher than in overweight children.

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