scholarly journals Effectiveness of lifestyle modification package among overweight and obese adolescent girls between 15-19 years with polycystic ovarian syndrome

2016 ◽  
Vol 4 (1) ◽  
pp. 84 ◽  
Author(s):  
Anju Krishnan Nair ◽  
Bindu Nambisan ◽  
Sreekumary Radha ◽  
Jayasree Leelamma
Keyword(s):  
Adolescent Girls ◽  
Intervention Program ◽  
Polycystic Ovarian Syndrome ◽  
Lifestyle Modification ◽  
Polycystic Ovary ◽  
Obese Adolescent ◽  
Menstrual Cycles ◽  
Cost Effective Treatment ◽  
Increased Risk ◽  
Ovarian Syndrome

Background: Polycystic ovarian syndrome (PCOS) is the most common female endocrine disorder which is often diagnosed during late adolescence, with anovulation and hyperandrogenism. Adolescent girls with PCOS, are at an increased risk for the development of type 2 diabetes mellitus and metabolic syndrome. Early diagnosis and early intervention may prevent long term sequelae and improve quality of life. The objectives were to study the effectiveness of lifestyle modification package among overweight and obese adolescent girls between 15-19 years with polycystic ovary syndrome (PCOS).Methods: In this study 144 adolescent girls (postmenarchal by 2 years) diagnosed as PCOS as per Rotterdam criteria after ruling out other causes of menstrual abnormality listed in the exclusion criteria, were selected. Informed consent taken from the participant or their parent if less than 18 years. Their anthropometric measurements and their menstrual cycles recorded at the beginning of the study and a lifestyle modification package including dietary modification and exercise, given to each of them. Participants were followed up telephonically every month to know their compliance towards the intervention program along with reinforcement of the package.  After 6 months of intervention they were reviewed to assess the effectiveness of the intervention package.Results: Significant weight loss was seen in 66.4% of the participants and15.2% had weight stabilization (weight gain <1.5kg). There was significant change in BMI with mean change in BMI 1.9. 58.4% of the girls improved their menstrual cycle after 6 months. There was significant reduction in body fat% and W/H ratio.Conclusions: Lifestyle modification is a simple, cost effective treatment in the management of overweight and obese adolescent PCOS in improving their BMI and regularization of menstrual cycles.

scholarly journals Study of prevalence and determinants of polycystic ovarian syndrome among adolescent girls in rural area: a prospective study

2019 ◽  
Vol 8 (8) ◽  
pp. 3135
Author(s):  
Manisha M. Laddad ◽  
Nitin S. Kshirsagar ◽  
Gauri P. Shinde ◽  
Vaishnavi S. Shivade
Keyword(s):  
Adolescent Girls ◽  
Polycystic Ovarian Syndrome ◽  
Lifestyle Modification ◽  
Polycystic Ovary ◽  
Cross Sectional Study ◽  
Reproductive Age ◽  
Adult Women ◽  
Cross Sectional ◽  
A Prospective Study ◽  
Ovarian Syndrome

Background: Polycystic ovarian syndrome (PCOS) is the most frequent endocrinological disorder affecting 5-10% of women in the reproductive age. This prevalence ranging from 2.2% to 26% in adult women from 18-45 year. In a recent study the prevalence of a confirmed diagnosis of PCOS in adolescents aged 10 to 19 years was 5-15%, which increased to 10-22%. When undiagnosed cases with documented symptoms qualifying for PCOS according to NIH (National institute of Health) criteria were included. PCOS is a complex endocrine disorder which is most common in women of reproductive age. PCOS may first present in adolescence, but the incidence of PCOS in adolescence is not known, as diagnostic criteria for PCOS in the adolescent age-group is still not defined, PCOS symptoms tend to overlap with normal pubertal changes making the diagnosis even more challenging. The objective is to study prevalence and symptomatology of polycystic ovary syndrome (PCOS) in adolescent girls.Methods: Prospective Cross sectional study between April 2018 and March 2019. 150 adolescent girls aged 10 to 19 years attending OPD with oligomenorrhea, irregular menstrual cycle, obesity and/or hirsutism were advised for biochemical, hormonal, and ultrasonographic evaluation for diagnosis of PCOS on the basis of Rotterdam's criteria at the Department of Obstetrics and Gynaecology, Krishna Institute of Medical Sciences, Deemed University, Karad, Maharashtra, India.Results: Prevalence of PCOS in the study was 17.33% in the study group.Conclusions: PCOS is increasingly encountered during adolescence, although the overall prevalence is low and evaluation of PCOS in adolescents is challenging. At this age, lifestyle modification is imperative to prevent long-term metabolic and reproductive complications.

scholarly journals Morning Circadian Misalignment Is Associated With Insulin Resistance in Girls With Obesity and Polycystic Ovarian Syndrome

2019 ◽  
Vol 104 (8) ◽  
pp. 3525-3534 ◽  
Author(s):  
Stacey L Simon ◽  
Laura McWhirter ◽  
Cecilia Diniz Behn ◽  
Kate M Bubar ◽  
Jill L Kaar ◽  
...  
Keyword(s):  
Adolescent Girls ◽  
Polycystic Ovarian Syndrome ◽  
Clinical Care ◽  
Cross Sectional ◽  
Obese Adolescent ◽  
Circadian Misalignment ◽  
Wake Time ◽  
Control Subjects ◽  
Sleep Timing ◽  
Ovarian Syndrome

Abstract Context To our knowledge, circadian rhythms have not been examined in girls with polycystic ovarian syndrome (PCOS), despite the typical delayed circadian timing of adolescence, which is an emerging link between circadian health and insulin sensitivity (SI), and decreased SI in PCOS. Objective To examine differences in the circadian melatonin rhythm between obese adolescent girls with PCOS and control subjects, and evaluate relationships between circadian variables and SI. Design Cross-sectional study. Participants Obese adolescent girls with PCOS (n = 59) or without PCOS (n = 33). Outcome Measures Estimated sleep duration and timing from home actigraphy monitoring, in-laboratory hourly sampled dim-light, salivary-melatonin and fasting hormone analysis. Results All participants obtained insufficient sleep. Girls with PCOS had later clock-hour of melatonin offset, later melatonin offset relative to sleep timing, and longer duration of melatonin secretion than control subjects. A later melatonin offset after wake time (i.e., morning wakefulness occurring during the biological night) was associated with higher serum free testosterone levels and worse SI regardless of group. Analyses remained significant after controlling for daytime sleepiness and sleep-disordered breathing. Conclusion Circadian misalignment in girls with PCOS is characterized by later melatonin offset relative to clock time and sleep timing. Morning circadian misalignment was associated with metabolic dysregulation in girls with PCOS and obesity. Clinical care of girls with PCOS and obesity would benefit from assessment of sleep and circadian health. Additional research is needed to understand mechanisms underlying the relationship between morning circadian misalignment and SI in this population.

scholarly journals Prevalence of polycystic ovarian syndrome among selected group of Sudanese housewives with infertility disorders

2019 ◽  
Vol 2 (01) ◽  
Author(s):  
Mohammed A.Gafoor A.Gadir ◽  
Mohammed Omer Mohammed Hussein ◽  
Mosab Nouraldein Mohammed Hamad
Keyword(s):  
Polycystic Ovarian Syndrome ◽  
Clinical Symptoms ◽  
Polycystic Ovary ◽  
Pancreatic Beta Cell ◽  
Reproductive Age ◽  
Ovary Syndrome ◽  
Cell Dysfunction ◽  
Increased Risk ◽  
Ovarian Syndrome

Polycystic ovary syndrome (PCOS), also recognized as the Stein-Leventhal syndrome, is one of the most widespread endocrinopathies between women of reproductive age. Hyperinsulinemia in mixture with pancreatic beta cell dysfunction consequences in an increased risk of numerous illnesses, counting type 2 diabetes, hypertension, dyslipidemia, endothelial dysfunction, atherosclerosis and cardiovascular diseases. Insulin also stimulates the theca cells of the ovary to create excessive testosterone, which is accountable for the clinical symptoms of hyperandrogenism

scholarly journals Effects of two monophasic oral contraceptives containing 150 mcg of desogestrel in combination with 20 or 30 mcg of ethinylestradiol on adolescent girls with oligomenorrhea and ovarian hyperandrogenism

1999 ◽  
Vol 48 (1) ◽  
pp. 53-58
Author(s):  
K. Nappi ◽  
F. Leone ◽  
A. Nicotra ◽  
M. J. Fareis ◽  
C. Dee Carlo ◽  
...  
Keyword(s):  
Adolescent Girls ◽  
Oral Contraceptives ◽  
Polycystic Ovarian Syndrome ◽  
Clinical Signs ◽  
Early Years ◽  
Menstrual Cycles ◽  
Ovarian Structure ◽  
Ovarian Hyperandrogenism ◽  
Ovarian Syndrome

Adolescent girls in the early years after their first menstruation are characterized by frequent irregular menstrual cycles and absence of ovulation, often associated with clinical signs of hyperandrogenism, including hirsutism and acne. Often in these adolescent girls, both the ovarian structure and endocrine characteristics do not allow to distinguish the disease from polycystic ovarian syndrome (PCOS) observed in adults.

scholarly journals Effectiveness of structured teaching programme regarding polycystic ovarian syndrome among adolescent girls

2021 ◽  
Vol 10 (7) ◽  
pp. 2818
Author(s):  
Soniya John
Keyword(s):  
Adolescent Girls ◽  
Polycystic Ovarian Syndrome ◽  
Polycystic Ovary ◽  
Sampling Technique ◽  
Reproductive Age ◽  
Teaching Programme ◽  
Structured Teaching ◽  
Prevention And Health Promotion ◽  
Quasi Experimental ◽  
Ovarian Syndrome

Background: Polycystic ovary syndrome is an endocrine disorder that affects approximately 5% of all women. It occurs amongst all races and nationalities. It is the most common hormonal disorder among women of reproductive age and is a leading cause of infertility. As polycystic ovarian syndrome is an ovarian disorder marked by a lack of estrogen, hyperandrogenaemia, obesity, hyper insulinaemia and starts early in the adolescent period. So, we should teach them regarding the clinical features treatment and prevention.Methods: A quasi experimental one group pre-test post design was adopted to assess the effectiveness of structured teaching programme on knowledge regarding polycystic ovarian syndrome among adolescent girls, Bangalore. A sample of 60 adolescent girls was selected from NRI higher secondary school, Bangalore by purposive sampling technique. Collected data was analysed by using descriptive and inferential statistics.Results: More than half 54 (90.0%) were having inadequate knowledge and 6 (10%) were having moderate knowledge regarding PCOS before STP.Conclusions: Structured teaching programme was significantly effective in increasing the knowledge of polycystic ovarian syndrome. The most important role of the nurse is to provide awareness on prevention and health promotion. 

scholarly journals Awareness of PCOS (polycystic ovarian syndrome) in adolescent and young girls

2017 ◽  
Vol 6 (6) ◽  
pp. 2297 ◽  
Author(s):  
Jayshree J. Upadhye ◽  
Chaitanya A. Shembekar
Keyword(s):  
Adolescent Girls ◽  
Polycystic Ovarian Syndrome ◽  
Lifestyle Modification ◽  
Accurate Diagnosis ◽  
Reproductive Age ◽  
Young Girls ◽  
Younger Age ◽  
Ovarian Syndrome ◽  
Age Awareness

Background: Polycystic ovarian syndrome (PCOS) is an endocrine disorder which affects the adolescent girls It affects 5% to 10% of women in their reproductive age. Awareness and accurate diagnosis is the first step in managing PCOS as it improves quality of life of the patient. The study was conducted to assess the knowledge on PCOS among the medical students.Methods: Survey of 200 girls was done to assess the knowledge on the polycystic ovarian syndrome among the medical students of different colleges studying in 1st, 2nd, and 3rd year. The data was collected from the students by using structured questionnaire.Results: In present study, 51% girls had normal BMI, 19.5% were overweight, 16.5% were obese while 13% were underweight. 33.5% females had acne, 16% had irregularity of menses, 5% had hirsutism while 2% had infertility. In present study, 33% adolescent and young girls had information about PCOS from teacher, 19% got information from friend, 11.5% got information from a doctor, 3.5% got information from newspaper while 5% got information from internet. 28% adolescent and young girls were unaware of PCOS.Conclusions: Thorough knowledge of the disorder and counseling for adolescents should be included in the curriculum which will provide awareness towards the disorder and lifestyle modification. Accurate diagnosis at a younger age may be a key.

scholarly journals Effect of Lifestyle Intervention on Features of Polycystic Ovarian Syndrome, Metabolic Syndrome, and Intima-Media Thickness in Obese Adolescent Girls

2011 ◽  
Vol 96 (11) ◽  
pp. 3533-3540 ◽  
Author(s):  
Nina Lass ◽  
Michaela Kleber ◽  
Katrin Winkel ◽  
Rainer Wunsch ◽  
Thomas Reinehr
Keyword(s):  
Blood Pressure ◽  
Weight Loss ◽  
Lifestyle Intervention ◽  
Adolescent Girls ◽  
Polycystic Ovarian Syndrome ◽  
Intima Media Thickness ◽  
Obese Adolescent ◽  
Media Thickness ◽  
The Impact ◽  
Ovarian Syndrome

Abstract Context: Polycystic ovarian syndrome (PCOS) is associated with cardiovascular risk factors (CRF). Lifestyle intervention is regarded as therapy of choice even if studies in adolescent girls with PCOS are scarce. Objective: Our objective was to analyze the impact of lifestyle intervention on menses irregularities, hyperandrogenemia, CRF, and intima-media thickness (IMT) in adolescent girls with PCOS. Patients: Patients included 59 obese girls with PCOS aged 12–18 yr. Intervention: Intervention was a 1-yr lifestyle intervention based on nutrition education, exercise training, and behavior therapy. Main Outcome Measures: Menses cycles, IMT, waist circumference, blood pressure, fasting lipids, insulin, glucose, testosterone, dehydroepiandrosterone sulfate, androstenedione, and SHBG were evaluated. Results: In contrast to the 33 girls without weight loss, the 26 girls reducing their body mass index during the lifestyle intervention (by a mean of −3.9 kg/m2) improved most CRF and decreased their IMT (by a mean of −0.01 cm). Testosterone concentrations decreased (by a mean of −0.3 nmol/liter) and SHBG concentrations increased (by a mean of +8 ng/ml) significantly in girls with weight loss in contrast to girls with increasing weight. The prevalence of amenorrhea (−42%) and oligoamenorrhea (−19%) decreased in the girls with weight loss. The changes in insulin in the 1-yr follow-up were significantly correlated to changes in testosterone (r = 0.38; P = 0.002) and SHBG (r = −0.35; P = 0.048). A linear regression model with changes in IMT as dependent variable demonstrated a significant association with changes in blood pressure and weight status but not with changes in testosterone. Conclusions: Weight loss due to lifestyle intervention is effective to treat menses irregularities, normalize androgens, and improve CRF and IMT in obese adolescent girls with PCOS.

scholarly journals Prevalence of Impaired Glucose Tolerance and Diabetes Mellitus in Women with Polycystic Ovarian Syndrome

2017 ◽  
Vol 3 (4) ◽  
pp. 116-118
Author(s):  
CH Chandra Smitha ◽  
Mo Orkoth Prasannan Anantha Sailakshmi ◽  
Rangaiah Nagaratnamma
Keyword(s):  
Diabetes Mellitus ◽  
Glucose Tolerance ◽  
Impaired Glucose Tolerance ◽  
Polycystic Ovarian Syndrome ◽  
Polycystic Ovary ◽  
Reproductive Age ◽  
Increased Risk ◽  
Management Of Complications ◽  
The Common ◽  
Ovarian Syndrome

ABSTRACT In women of reproductive age polycystic ovary syndrome (PCOS) is the common endocrine disorder. It is one of the common causes of infertility due to anovulation. There is no single criterion for the diagnosis of this syndrome. It is crucial to diagnose PCOS early in its course since it has lifelong implications with increased risk for metabolic syndrome, type II Diabetes mellitus (DM), cardiovascular disease, endometrial hyperplasia, infertility and depression. Screening for the impaired glucose (IGT), allows for proper and timely prevention and management of complications. In this cross sectional study, we planned to detect the prevalence of impaired glucose tolerance and diabetes in women with PCOS which will facilitate prevention of long term sequelae. We also studied the extent of the risk for diabetes in patients with PCOS in relation to age, socioeconomic status, rural and urban areas, BMI, waist/hip circumference ratio, family history of PCOS and diabetes mellitus How to cite this article Smitha CHC, Sailakshmi MOPA, Nagaratnamma R. Prevalence of Impaired Glucose Tolerance and Diabetes Mellitus in Women with Polycystic Ovarian Syndrome. J Med Sci 2017;3(4):116-118.

scholarly journals Valproate, bipolar disorder and polycystic ovarian syndrome

2016 ◽  
Vol 69 (3-4) ◽  
pp. 121-126 ◽  
Author(s):  
Milana Okanovic ◽  
Olga Zivanovic
Keyword(s):  
Bipolar Disorder ◽  
Polycystic Ovarian Syndrome ◽  
Treatment Guidelines ◽  
Polycystic Ovary ◽  
The United States ◽  
Reproductive Age ◽  
Hormonal Changes ◽  
Polycystic Ovaries ◽  
Increased Risk ◽  
Ovarian Syndrome

Introduction. Polycystic ovarian syndrome is a syndrome of ovarian dysfunction with the principal features of hyperandrogenism and polycystic ovary morphology. A large number of studies conducted on this topic have suggested a possible role of anticonvulsants, particularly valproate, in the pathogenesis or risk factors associated with polycystic ovarian syndrome. Bipolar treatment guidelines from Canada and the United States of America recommend valproate as the first line strategy in the acute treatment of bipolar disorder. Discussion. Most persons with bipolar disorder require maintenance treatment. Long-term administration of valproate in women with bipolar disorder or epilepsy is believed to result in the increased risk of hyperandro?genism, menstrual abnormalities and polycystic ovaries. Valproate may also increase the risk of infertility and other associated symptoms of polycystic ovarian syndrome. Therefore, particular caution is indicated in the use of valproate in women of reproductive age. Conclusion. The treatment of the female patients with bipolar disorder presents various challenges for the clinician. Every woman of reproductive age needs to know the risk and benefits of her pharmacologic treatment options. Bipolar disorder should be considered chronic disorder, whose development is largely affected by hormonal changes and reproductive cycle in women. These issues should be researched more thoroughly in order to opt for the most appropriate treatment in women with bipolar disorder.

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