scholarly journals Prevalence of uncontrolled hypertension and associated factors among hypertensive patients attending medical outpatient clinic, Thika level 5 hospital, Kenya

Author(s):  
Magara Monyenye Gladys ◽  
John Gachohi ◽  
Alex Muriithi

Background: Uncontrolled hypertension is a key risk factor for stroke and heart and kidney disease. A study was conducted to determine the factors associated with the prevalence of uncontrolled hypertension among hypertensive patients (study participants) attending a medical outpatient clinic, Thika level 5 Hospital (TL5H), Kenya.Methods: The study adopted a cross-sectional study design and a mixed-methods approach. While the quantitative arm sampled 394 study participants using systematic random sampling, purposive sampling selected 18 health care workers who served as key informant sand 35 study participants took part in focus group discussions in the qualitative arm. Uncontrolled hypertension was defined as systolic and or diastolic blood pressure ≥140 and or ≥90 in one or both previous and current readings during clinic visits. Quantitative data including socio-demographic, socioeconomic, and clinical characteristics of study subjects were collected using interviewer-administered questionnaires. Qualitative data were collected using guides and checklists. Data were analysed descriptively and inferentially using Pearson’s chi-square statistics, Fishers exact tests and regression modelling to determine associations between independent variables and uncontrolled hypertension using STATA 14. Qualitative data were organized thematically using NVIVO.Results: 48% of the study participants had uncontrolled hypertension at the time of the study.  Univariable analyses returned level of education (p=0.017), source of financing for hypertensive drugs (p=0.011), BMI (p=0.005) as significant factors.Conclusions: The study recommends community health promotion activities to increase awareness of how to modify these significant factors to reduce hypertension.

2020 ◽  
Vol 7 (2) ◽  
pp. 256-263
Author(s):  
Abdul Qodir

Penatalaksanaan farmakologis dan non farmakologis dipercaya dapat mengontrol tekanan darah dan mencegah komplikasi, tetapi banyak pasien hipertensi tekanan darahnya tidak terkontrol. Hal tersebut dikarenakan kepatuhan yang buruk dalam melaksanakan rekomendasi gaya hidup. Penelitian ini bertujuan untuk menganalisis determinan faktor yang berhungan dengan kepatuhan melaksanakan rekomendasi modifikasi gaya hidup. Penelitian ini menggunakan metode cross-sectional di pukesmas dinoyo Kota Malang tahun 2019. Teknik pengambilan sampel menggunakan Consecutive Sampling. Kuesioner yang digunakan meliputi : karakteristik demografi, pengetahuan dan rekomendasi mofifikasi gaya hidup pasien hipertensi. Hubungan antara rekomendasi modifikasi gaya hidup dengan variabel independen dianalisis menggunakan uji chi square dan analisis regresi logistik. 140 pasien hipertensi berpartisipasi dalam penelitian ini (60 laki-laki, 80 wanita). Prevalensi kepatuhan adalah 28,6 %. Tingkat pengetahuan berhubungan signifikan  dengan kepatuhan melaksanakan rekomendasi gaya hidup (p=0,00). Jenis kelamin, usia, dan tingkat pendidikan tidak mempunyai hubungan signifikan dengan kepatuhan rekomendasi modifikasi gaya hidup (p= 0,06; p=0,21; p=0,87). Pengetahuan mempunyai hubungan yang signifikan dengan kepatuhan rekomendasi modifikasi gaya hidup. Management of pharmacological and non-pharmacological is believed to control blood pressure and prevent complications,  but many hypertensive patients have uncontrolled blood pressure. This is due to poor adherence to recommended lifestyle modifications. This study was aimed to determine the factors associated with adherence to recommended lifestyle modifications of hypertensive patients. A cross-sectional study was conducted in Pukesmas Dinoyo Malang in 2019. Consecutive Sampling was used to select study subjects. The questionnaire included information about demographic characteristics, knowledge, practice of lifestyle-modification measures. Associations between adherence to lifestyle modification and independent variables were analyzed using chi square and multivariate logistic regression analysis. 140 hypertensive patients participated in the study (60 men, 80 women). The prevalence of adherence was 28.6%. The level of knowledge was significant associated with adherence to recommended lifestyle modifications (p = 0.00). Genders , age, and educational level were no significant associated with to recommended lifestyle modifications (p= 0.06; p=0.21; p=0.87). Knowledge was significant associated with adherence to recommended lifestyle modifications of hypertensive patients.


2019 ◽  
Author(s):  
Assefa Iyasu Negash ◽  
Desta Siyoum ◽  
Tsega Hailemariam ◽  
Berihu Hailu Kidanu ◽  
Gebreamlak Gebremdhin Gebremeskel ◽  
...  

Abstract Background: - Uncontrolled hypertension is if SBP is ≥140 mm Hg and/or DBP ≥90 mm Hg for general hypertensive population or if SBP ≥130 mm Hg and/or DBP ≥80 mm Hg in patients with established diabetes mellitus or chronic kidney disease based on the average of two or more properly measured, seated, BP readings on each of two or more office visits. The aim of this study was to assess the magnitude of uncontrolled hypertension and associated factors among adult hypertensive patients in public hospitals of central zone, Tigray, Ethiopia, 2018. Methods:- A hospital based cross sectional study design was used. The study population was all sampled adult hypertensive patients who had follow up in public hospitals of central zone, Tigray and the data collection period was from March 01 to April 30, 2018. About 421 study participants were selected using systematic random sampling. Interviewer administered structured questionnaire, chart review checklist and measurements were used. The collected data was checked for its completeness manually and then entered and cleaned in to epi data version 3.1 and exported to Statistical packages for social science version 22 for analysis. Bivariate and multivariable analyses were done to identify factors of uncontrolled hypertension. Then those variables significant at p<0.25 with the outcome variable in bivariate analysis were selected for multivariable analysis and odds ratio with 95% confidence level was computed and p-value < 0.05 was described as a significant association in multivariable analysis. Result: - Among 421 respondents about 177(42%) had uncontrolled hypertension. Co-morbidity [AOR=0.36, (0.205, 0.631)], five to ten years duration of medication taken [AOR=0.398, (0.218, 0.725)], side effect of medication [AOR=0.542, (0.339, 0.866)] and medication adherence [AOR=4.092, (2.419, 6.924)] were significantly associated with uncontrolled hypertension. Conclusion: - In this study the magnitude of uncontrolled hypertension was high. Co-morbidity, antihypertensive medication taken for long duration, side effect of antihypertensive medication and non adherence to antihypertensive medication shows statistical association with uncontrolled hypertension.


2021 ◽  
Vol 3 (1) ◽  
pp. 67-76
Author(s):  
Martin Buuri ◽  
Michael Gicheru ◽  
Joshua Mutiso ◽  
Festus Mulakoli

Although fungi are known to be less pathogenic and mostly saprophytic in their nature as compared to other groups of microbes, those that produce aflatoxin have been associated with severe human disease. An example of such disease is Aflatoxicosis caused by soil-borne pathogenic fungi of the species Aspergillus parasiticus and Aspergillus flavus. They produce a mycotoxin substance that is carcinogenic to the human liver with severe outcomes. The objective of this study was to determine urinary aflatoxin levels among the residents of Makueni County, previously affected by Aflatoxicosis. This was a cross-sectional study that involved the use of primary data collected from 106 participants. The method for data collection included a structured questionnaire and the collection of the urine samples for aflatoxin M1 analysis at Bora Biotech Laboratories LTD. The urinary levels of AFM1 were detected by use of an ELISA kit. Data was entered in SPSS and analysed through Chi-Square for the association. The study participants, including both male and female, had an age of between 15 and 91 years and with an average age of 41±18. Out of the 106 study participants, n=68 (72%) were females and n=26 (28%) were males. Majority of the study participants were with a median age of 24 years old. AFM1 levels were detected in 99.1% % of all urine samples at a range of 25-2337 pg./ml. The mean and median concentration of AFM1 in urine was 637.6 ± 512.7and 525 pg./mL, respectively. The results of this study provide information on the current situation of aflatoxin exposure. From what is evident from our study a lot needs to be done to mitigate on the long-term effect of this high exposure.  Therefore, the study encourages the concerned ministry to have a broader focus on the extent of aflatoxin food contamination from this region plus other regions across the country.


Author(s):  
Ajediran I Bello ◽  
Love Kanebi ◽  
Fidelis T Iyor ◽  
Babatunde O A Adegoke

Background: The rehabilitation phase of patients with lower extremity fractures (LEF) is often hindered post-operatively by fear of moving (kinesiophobia) with consequent deconditioning and declining of functions. Profiling the prevalence of kinesiophobia and its association with demographic variables could become useful during the rehabilitation process. Objective: The study aimed to determine the prevalence of kinesiophobia and its correlation with lower limb functions among patients with LEF post-operatively. Methods: One-hundred and nine (n = 109) patients [male = 79 (72.50%)] with mean age of 41.83 ± 17.37 yr. participated in the cross-sectional study. Participants with LEF who had either undergone closed reduction and immobilization or open reduction with internal or external fixation were recruited into this study using convenience sampling during the rehabilitation phase at the orthopaedic wards of two tertiary healthcare facilities in Accra. Data collection was performed using the Tampa Scale of Kinesiophobia (TSK) and Lower Extremity Functional Scale. Data were analyzed using Spearman’s Rho correlation coefficient and Chi-square tests at p < 0.05.Results: Seventy-nine (72.50%) of the participants exhibited kinesiophobia based on their TSK scores (≥37). The TSK scores were significantly inversely correlated with participants’ lower limb function (r = -0.345; p < 0.001). Participants’ sex as well as the causes, types and sites of the fractures sustained had no significant association (p > 0.050) with the level of kinesiophobia. Conclusion: There was a high prevalence of kinesiophobia which negatively correlated with LEF but was not associated with the type, site, and cause of fracture as well as the participants’ sex. Mitigating kinesiophobia should always be considered an integral rehabilitation goal for in-patients with LEF.


2021 ◽  
pp. 01-11
Author(s):  
Eklas Abdunasir ◽  
Teshome Sosengo ◽  
Frehiwot Amare ◽  
Mohammed Yimam ◽  
Bisrat Hagos

Background: Counterfeit medicines are drugs which are deliberately and fraudulently mislabeled with respect to identity and/or source. According to the WHO 2017 report, about 1% of prescribed medicines in the developed world and about 10-50% in parts of the developing world are estimated to be counterfeits. Objective: The objective of this study was to assess the knowledge and attitude of pharmacy profes-sionals towards counterfeit medicines in Harar town. Method: A cross sectional study was conducted among pharmacy professionals found in Harar town, East Ethiopia. All pharmacy professionals working in community drug retail outlets of Harar town was included in the study. Accordingly, 92 pharmacy professionals were included in the study. The data was collected by using self-administered questionnaire. The questionnaire was prepared in English language. Data was coded, entered and analyzed by using Statistical Package for Social Sci-ence version 22. Then chi-square(x2) test was performed to determine there exists association of so-cio-demographic characters, profession and year of service towards awareness and attitude about counterfeit medicines was investigated using. Result: A total of 92 respondents were included in the study. The majority, 76 (82.6%), of the study participants had information about counterfeit medicine. The 26(28.3%), 42(45.7%) and 24(26%) of the respondents replied that counterfeit medicines have problem of efficacy, safety and cause eco-nomic problem on sellers of genuine drugs respectively. Majority of the study of the study partici-pants were not aware of a way of identification of counterfeit medicines, with only 18(19.6%), 47(51.1%) and 27(29.3%), replied that counterfeit medicines can be identified by its effect, inspec-tion and cost respectively. Majority of the respondents, 60(65.2%), responded that pharmacy profes-sional that knowingly dispense counterfeit medicine are business man /women. Most of the re-spondents, 66(71.7%), replied that pharmacy professionals carry out the business of counterfeit medicines transaction because of big profit obtained from such an activity. gender, profession and year of service in serving as pharmacy professional was found to be significantly associated with awareness towards counterfeit medicines, (p<0.05). Conclusion: Significant proportion of the study participants were not aware of the problems associ-ated with counterfeit medicines as efficacy, safety and economic problems. Majority of the respond-ents still are unaware about ways of identification of counterfeit medicines as inspection, by effica-cy and cost. Keywords: Counterfeit medicines; Awareness; Attitude; Professionals; Drug retail outlets


2021 ◽  
Author(s):  
MULUALEM ALEMAYEHU ◽  
Sintayehu Abebe ◽  
Dejuma Yadeta ◽  
Bekele Alemayehu

Abstract Background: Hypertension is the most common cardiovascular problem globally with a particularly increasing burden in developing countries like Ethiopia. Ambulatory blood pressure (ABPM) is superior to office blood pressure (OBP) measurement for diagnosing, prognosticating and following treatment efficacy for hypertension. There is no available data on ABPM control pattern in Ethiopians. This study will determine the ABPM control patterns in Ethiopian hypertensive patients on treatment. Material and Methods: This was a cross sectional study in hypertensive patients at Tikur Anbessa Specialized Hospitals outpatient departments carried out during January to May 2021. ABPM values of 244 consecutively sampled patients were analyzed. All patients had their BP monitored over 24 h with a Tonoport V (GE CS V6 71), and the data was interpreted using GE CardiosoftTM ABPM software in accordance with European Society of hypertension guidelines. Ethical clearance was given by Addis Ababa University Institutional Review Board and the study was conducted in compliance to standard ethical guidelines.Results: The study involved 244 adult hypertensive patients; mean age of the patients was 59.4years and, 54% were females. 58.6% of patients had controlled OBP, while only 45.1% had controlled ABPM. The mean OBP was 137 (19)/81 (10) mmHg and mean 24-hr ABP was 137 (16)/81 (10) mmHg; mean daytime BP was 136/79 ± 17/11 mmHg; mean night‑time BP, 138/84 ± 16/11 mmHg. Mean ABPM values were not significantly different between men and women. Comparison of ABPM values with OBP revealed high prevalence of the white coat effect (32%) and masked uncontrolled hypertension (46%). Presence of comorbidities particularly diabetes predicted poor ABPM control.Conclusion: More than half of patients had uncontrolled BP as per ABPM criteria and significant discrepancy exists between ABPM and OBP in assessing adequacy of BP control. Guiding management decisions using ABPM can improve BP control rates.


Author(s):  
Pratibha Rao Katapadi ◽  
Dattatreya D. Bant

Background: Hypertension is a significant public health issue worldwide and can have deleterious effects on the health when it is not under control. Adherence to antihypertensive medications is thus necessary for better control of blood pressure and to reduce the risk of complications. There are various factors which support or hinder the patient’s adherence to anti- hypertensive treatment. Thus this study was done to reflect the factors influencing the adherence to antihypertensive drugs among urban and rural population.Methods: A community based cross sectional study was conducted in urban and rural field practice areas of Karnataka Institute of Medical Sciences, Hubballi. A semi-structured questionnaire was used for data collection among the known hypertensive patients. The data was entered in Microsoft Excel and analysed using SPSS software.Results: Most of the hypertensive patients were aged 45 and above (89.5%). A total of 73.5% of the participants were adherent to antihypertensive medications and adherence was more among urban (76%) as compared to rural population (71%). Knowledge regarding complications of uncontrolled hypertension was the major factor for adherence in both the areas. The mean systolic and diastolic blood pressure was controlled in patients who were adherent.Conclusions: There is a higher level of adherence to antihypertensive medications in urban population as compared to rural population of Hubballi. The findings suggest patient factors, clinical factors and socio-demographic factors play an important role in determining the adherence to the medication.


2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Degena Bahrey ◽  
Gebreamlak Gebremedhn ◽  
Teklewoini Mariye ◽  
Alem Girmay ◽  
Woldu Aberhe ◽  
...  

Abstract Objective The aim of this study was to assess the prevalence of chronic kidney disease and to identify associated factors of chronic kidney disease among hypertensive patients. A cross-sectional study was conducted among selected 578 hypertensive patients. Data were collected using face to face interviewing questionnaires and from medical chart review. Binary logistic regression analyses were performed and analyzed using SPSS version 23.0. Result Of the total 578 hypertensive patients the prevalence of chronic kidney disease was found to be 128 (22.1%). Of these hypertensive patients, patients with uncontrolled blood pressure, overweight/obesity, dyslipidemia and diabetic mellitus, 43.3%, 33.7%, 27.3% and 28.2 respectively. After adjustment, the independent variables the significant associated factors of chronic kidney disease among hypertensive patients were age [AOR (95% CI 1.43 (1.07–1.81)], uncontrolled hypertension 4.434 [AOR (95% CI 9.45 (1.34, 14.73)], overweight/obese [AOR (95% CI 7.422 (2.72, 20.28)], dyslipidemia [AOR (95% CI) 13.749 (5.69, 33.215)], diabetic mellitus [AOR (95% CI) 2.137 (1.07, 4.26)]. In conclusion, the prevalence of chronic kidney disease was considerably high. The major associated factors of chronic kidney disease were age, uncontrolled hypertension, overweight/obese, diabetic mellitus and dyslipidemia.


2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Chanyalew Worku Kassahun ◽  
Ayele Asasahegn ◽  
Desalegn Hagos ◽  
Elshaday Ashenafi ◽  
Firegenet Tamene ◽  
...  

Background. Patients with hypertension need to be aware of various aspects of hypertension and exercise self-care. But, there is limited information regarding this issue. Objective of the Study. This study was designed to assess knowledge on hypertension and self-care practice among adult hypertensive patients in the University of Gondar Comprehensive Specialized Hospital, Ethiopia. Materials and Methods. Descriptive cross-sectional study was conducted among 384 hypertensive patients from April to May 2019. The study participants were selected using a systematic random sampling technique. Data were collected using a pretested interviewer-administered questionnaire. Descriptive statistics such as percentage and frequency of patients’ knowledge on hypertension and their self-care practice were computed. Cross-tabulation was used to see the frequency and percentage of selected sociodemographic variables and knowledge level with self-care practice subscales. Finally, the results were summarized and presented in texts, figures, and tables. Results. Among the study participants, 215 (56%) and 228 (59.4%) had good knowledge and self-care practice towards hypertension, respectively. The participants who had good knowledge had good self-care practice frequency. Conclusions. In this study, knowledge on hypertension was low, while self-care practice was moderate on the self-care interventions. Hence, increasing patients’ awareness and intervention on medication adherence, low salt diet consumption, physical activity, weight management, cigarette smoking cessation, and alcohol consumption reduction is important.


Open Medicine ◽  
2008 ◽  
Vol 3 (2) ◽  
pp. 221-224 ◽  
Author(s):  
Aleksandra Jovic-Vranes ◽  
Bjegovic Vesna ◽  
Vranes Boris ◽  
Milic Natasa

AbstractThe study was undertaken to assess job satisfaction among health care workers (HCWs) who work with disabled patients and to identify the factors that contribute to their job satisfaction. This was a cross-sectional study conducted at nine rehabilitation centers in Serbia. The study sample consisted of doctors, nurses, physiotherapists, and other HCWs (social workers, work and speech therapists, and psychologists). A self-administrated questionnaire was distributed to 170 HCWs. Chi square testing and multivariate logistic regression analyses were applied. The response rate was 97.1% (165/170). Overall job satisfaction was reported by 22.4% of the respondents and was associated with hospital politics (odds ratio [OR], 4.16; 95% confidence interval [CI], 1.13–15.30], personal relationships (OR, 13.96; 95% CI, 4.07–47.92) and the feeling of being able to provide a good quality of care (OR, 5.24; 95% CI, 1.62–16.99). Profession, age, and gender did not affect job satisfaction. In conclusion, the results show very low job satisfaction among HCWs. Improving contributing factors may lead to higher job satisfaction and a better quality of health care.


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