scholarly journals A peculiar case of cancer en cuirasse in adenocarcinoma rectum

2020 ◽  
Vol 6 (5) ◽  
pp. 190
Author(s):  
Parul Gupta ◽  
Ashish Nigam ◽  
Anil K. Dhull ◽  
Arpit Mittal
Keyword(s):  
Case Reports ◽  
Young Female ◽  
Cutaneous Metastasis ◽  
Primary Adenocarcinoma ◽  
Cutaneous Metastases ◽  
Elderly Individuals ◽  
Morphological Variant ◽  
Rare Phenomenon ◽  
Sixth Decade ◽  
Peculiar Case

<p>Cancer en cuirasse in a case of primary adenocarcinoma rectum is an exceedingly rare phenomenon which is scarcely seen in isolated case reports only. It is a specific morphological variant of cutaneous metastasis characterised by diffuse induration and oedema of cutis which is studded with carcinomatous lesions. Cutaneous metastases often occur in elderly individuals in their sixth decade or later. Herein we present a case of carcinoma en cuirasse arising in a young female who was operated for adenocarcinoma rectum.</p>

scholarly journals Cutaneous Metastasis in the Setting of Both Colon and Breast Primary Malignancies

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Mary Junak ◽  
Hunter Jecius ◽  
Jennifer Erdrich ◽  
Shiro Kikuchi
Keyword(s):  
Ductal Carcinoma ◽  
Case Reports ◽  
Colon Adenocarcinoma ◽  
The United States ◽  
Punch Biopsy ◽  
Left Breast ◽  
Cutaneous Metastasis ◽  
Cutaneous Lesions ◽  
Cutaneous Metastases ◽  
Colonic Primary

Colorectal cancer (CRC) is the third most diagnosed cancer in the United States, and many patients unfortunately have metastases at the time of their diagnosis. Cutaneous metastases of CRC have been reported in few journals and primarily as case reports due to their rarity. Here, we present the case of an 83-year-old woman with recently resected colon cancer, T4aN1bMx stage IIIB. She presented to our clinic for evaluation of a right midback mass, and a punch biopsy revealed dermal involvement by invasive, poorly differentiated carcinoma with epidermoid features. The mass was excised, and we ordered a PET scan in search of the primary tumor, which at that time was suspected to be of skin cancer origin. Surprisingly, this revealed a second malignancy triple-negative invasive ductal carcinoma of the left breast. The back mass stained positive for CK20, which was compatible with a metastasis from a colonic primary. After initially declining adjuvant therapy, the patient completed one cycle of capecitabine and oxaliplatin, which she tolerated poorly. She continued to further decline, developed widespread cutaneous metastases, and went home on hospice. Cutaneous lesions are an exceedingly rare site of metastasis for colon adenocarcinoma, and their clinical presentation can vary widely. It is important for providers to investigate any new skin lesion in a patient with a recent or remote history of malignancy, even if there were no sites of distant metastasis at initial diagnosis.

scholarly journals Cutaneous Metastasis of Prostate Adenocarcinoma: A Rare Presentation of a Common Disease

2021 ◽  
Vol 9 ◽  
pp. 232470962199076
Author(s):  
Alexander Dills ◽  
Okechukwu Obi ◽  
Kevin Bustos ◽  
Jesse Jiang ◽  
Shweta Gupta
Keyword(s):  
Prostate Cancer ◽  
Serine Proteases ◽  
Cancer Genetics ◽  
Performance Status ◽  
Distant Metastases ◽  
The United States ◽  
Cutaneous Metastasis ◽  
Common Disease ◽  
Cutaneous Metastases ◽  
Rare Presentation

Prostate cancer is the most common cancer affecting men in the United States and the second greatest cause of cancer-related death. Metastases usually occur to bone followed by distant lymph nodes and then viscera. Cutaneous metastases are extremely rare. Their presence indicates advanced disease and a poor prognosis. As they are highly variable in appearance and may mimic a more benign process, biopsy is essential for identification. Serine proteases, particularly human tissue kallikreins, may play an important role in promoting metastasis and facilitate infiltration of the skin. Individual cancer genetics may predispose to more aggressive cancer and thus earlier and more distant metastases. In this article, we report our case of a 67-year-old man with a 4-year history of castrate-resistant prostate cancer with cutaneous metastases confirmed by histology. Despite multiple lines of systemic therapy, the patient suffered progressive disease with worsening performance status and was enrolled in hospice.

scholarly journals Anaplastic myxopapillary ependymoma of the sacrum: A case report

2021 ◽  
Vol 12 ◽  
pp. 285
Author(s):  
Abolfazl Rahimizadeh ◽  
Zahed Malekmohammadi ◽  
Parviz Habibollahzadeh ◽  
Walter L. Williamson ◽  
Ava Rahimizadeh
Keyword(s):  
Back Pain ◽  
Case Report ◽  
Lower Back Pain ◽  
Medical Literature ◽  
Case Reports ◽  
Surgical Excision ◽  
Young Female ◽  
Myxopapillary Ependymoma ◽  
Case Description ◽  
Lower Back

Background: Myxopapillary ependymoma (MPE) with anaplastic features is extremely rare. There are very few such case reports in the medical literature. Case Description: A 23-year-old female presented with lower back pain, and both urinary and fecal dysfunction. The patient underwent gross total surgical excision of the MR documented expansile intrasacral tumor. The histology was compatible with a MPE containing anaplastic features. Conclusion: The medical literature contains a few comparable cases of subcutaneous sacrococcygeal MPE with anaplastic components. Here, however, we have a young female with an anaplastic intrasacral MPE treated with gross total surgical excision.

scholarly journals ’Carcinoma en cuirasse' in the neck: extremely unusual initial presentation of gastric cancer

2019 ◽  
Vol 12 (4) ◽  
pp. e228418 ◽  
Author(s):  
Madhu Rajeshwari ◽  
Pirabu Sakthivel ◽  
Kapil Sikka ◽  
Deepali Jain
Keyword(s):  
Gastric Cancer ◽  
Clinical Presentation ◽  
Cutaneous Metastasis ◽  
Initial Presentation ◽  
Cutaneous Lesions ◽  
Internal Malignancy ◽  
Metastatic Lesions ◽  
Unusual Form ◽  
Rare Phenomenon ◽  
Visceral Malignancy

Cutaneous metastasis from visceral malignancy is a relatively rare phenomenon. It is even rarer to have cutaneous lesions as the first mode of clinical presentation in such malignancies. The lesions are usually nodular, although they can have varied appearances. Common sites of primaries include breast, lung, colorectum, kidney, ovary, and headandneck. We report an unusual form of cutaneous metastasis in the neck, known as ‘carcinoma en cuirasse’, in an elderly man that subsequently led to the diagnosis of an occult gastric cancer. Our case highlights the importance of recognising cutaneous metastatic lesions early, as they may herald the diagnosis of an occult internal malignancy.

scholarly journals 063 Headache with periorbital ecchymosis; a rare clinical entity

2019 ◽  
Vol 90 (e7) ◽  
pp. A20.3-A21
Author(s):  
Srimathy Vijayan ◽  
Carolyn Orr ◽  
Catherine Franconi
Keyword(s):  
Case Reports ◽  
Tension Headache ◽  
Primary Headache ◽  
Young Female ◽  
Clinical Entity ◽  
List Type ◽  
Treatment Regimens ◽  
Primary Headache Disorders ◽  
Headache Pain ◽  
Trigeminal Autonomic Cephalgia

ObjectivesPrimary headache disorders are common with migraine and tension headache accounting for the vast majority of cases. A smaller proportion suffer from trigeminal autonomic cephalgia (TAC). We present a 23-year-old Caucasian female who described characteristic, episodic headaches starting with a dull retro-orbital/bi-frontal pressure evolving, over the course of 1 minute, to experience florid periorbital ecchymosis. While this phenomenon has been described in the literature, the characteristics of our case are unique and noteworthy of reporting.MethodsWe reviewed the literature surrounding this rare entity by using PubMed/OVID databases and the search terms ‘Headache AND ecchymosis’.ResultsCase reports exist in older patients1–3, where the headache is side locked and associated with other autonomic characteristics such as periorbital oedema, conjunctival injection and tearing. Our case is a young female with only ecchymosis in a unilateral and/or bilateral manner and no other autonomic or indeed migraine features. The patient underwent vascular/cranial imaging and blood tests to exclude haematological, autoimmune, vasculitic causes for this presentation which were unrewarding.ConclusionVariations on this clinical entity are described;1–4 we hope this report may bring attention to this fascinating phenomenon. The pathophysiological process is likely to be similar to those implicated in TACs, namely activation of the trigemino-neurovascular system and facial autonomic pathways. The release of neuromediators such as CGRP, VIP and Substance P cause blood vessel fragility resulting in diapedesis. Optimal treatment regimens are unknown but various agents have been trialled. Our patient declined treatment and continues to be followed.ReferencesDeBroff B, et al. Migraine Associated with Periorbital Ecchymosis. Headache 1990;30:260–263.Dafer R, et al. Atypical Chronic Headache and Recurrent Facial Ecchymosis: A Case Report. Neuro-Ophthalmology 2011;35:76–77.Nozzolillo D, et al. Migraine associated with facial ecchymoses ipsilateral to the symptomatic side. J Headache Pain ( 2004) 5:256–259.Sethi PK, et al. Teaching neuroimages: Red forehead dot syndrome and migraine revisited. Neurology 2015;85;e28.

scholarly journals Hemangioma of the Tympanic Membrane: A Case and a Review of the Literature

2012 ◽  
Vol 2012 ◽  
pp. 1-3 ◽  
Author(s):  
Emilio Mevio ◽  
Marco Cazzaniga ◽  
Mauro Mullace ◽  
Donatella Paolotti
Keyword(s):  
Tympanic Membrane ◽  
External Auditory Canal ◽  
Case Reports ◽  
Benign Neoplasm ◽  
Surgical Excision ◽  
Vascular Tumor ◽  
Surgical Approaches ◽  
Review Of The Literature ◽  
Bony Canal ◽  
Sixth Decade

Hemangiomas of the external auditory canal, involving the posterior bony canal and the adjacent tympanic membrane, although rare, are considered a specific disease entity of the human external auditory canal. Hemangiomas of the tympanic membrane and/or external auditory canal are rare entities; there are 16 previous case reports in the literature. It is a benign vascular tumor. It generally occurs in males in the sixth decade of life. Total surgical excision with or without tympanic membrane grafting appears to be effective in the removal of this benign neoplasm. The authors present a case and a review of the literature discussing diagnostic and surgical approaches.

ʺStomatologyʺ in functional endoscopic sinus surgery – 2 case reports

2018 ◽  
Vol 7 (2) ◽  
pp. 43-47
Author(s):  
Paulina Kołodziejczyk ◽  
Tomasz Gotlib
Keyword(s):  
Chronic Rhinosinusitis ◽  
Endoscopic Surgery ◽  
Paranasal Sinuses ◽  
Endoscopic Sinus Surgery ◽  
Case Reports ◽  
Functional Endoscopic Sinus Surgery ◽  
The Body ◽  
Sinus Surgery ◽  
Facial Region ◽  
Rare Phenomenon

Functional endoscopic sinus surgery (FESS) is most commonly used in chronic rhinosinusitis treatment. This method is also applicable to other diseases, including the treatment of symptomatic ectopic teeth. Ectopic teeth are a quite rare phenomenon. They may appear within the facial region, as well as in other parts of the body. The article describes two cases of ectopic teeth appearing within the nose area and paranasal sinuses, there endoscopic surgery has been used in the extraction, which resulted in the remission of symptoms.

scholarly journals Choroidal and Cutaneous Metastasis from Urothelial Carcinoma of the Bladder after Radical Cystectomy: A Case Report and Literature Review

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Yozo Mitsui ◽  
Naoko Arichi ◽  
Keita Inoue ◽  
Miho Hiraki ◽  
Shigenobu Nakamura ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Radical Cystectomy ◽  
Metastatic Potential ◽  
Cutaneous Metastasis ◽  
Bladder Cancer Patient ◽  
Lower Abdomen ◽  
Cutaneous Metastases ◽  
Multiple Metastases ◽  
Carcinoma Of The Bladder ◽  
The Right

Bladder cancer is the second most common genitourinary malignancy and has variable metastatic potential; however, choroidal and cutaneous metastases are extremely rare. Generally, a patient with these uncommon metastases has a very poor prognosis. We present a bladder cancer patient with a visual disorder in the right eye and multiple nodules on head and lower abdomen that developed 17 months after a radical cystectomy. These symptoms were determined to be caused by choroidal and cutaneous metastasis of bladder cancer. Although two cycles of combination chemotherapy were performed, the patient died 5 months after diagnosis of multiple metastases.

scholarly journals Penile metastasis of urothelial carcinoma diagnosed by fine-needle aspiration

CytoJournal ◽  
2009 ◽  
Vol 6 ◽  
pp. 10 ◽  
Author(s):  
Gilda da Cunha Santos ◽  
Marcia Lanzoni de Alvarenga ◽  
Vinicius Freitas Borlot ◽  
Michel Antonio Kiyota Moutinho ◽  
Marcello Fabiano de Franco
Keyword(s):  
Urothelial Carcinoma ◽  
Fine Needle Aspiration ◽  
Case Reports ◽  
Needle Aspiration ◽  
Cutaneous Metastasis ◽  
Fine Needle ◽  
Penile Metastasis ◽  
Systemic Spread ◽  
Initial Procedure ◽  
The Rich

Penile neoplasms are rare and can be primary or represent metastasis or local recurrence. The most common primary cancer of the penis is squamous cell carcinoma, accounting for 95% of all cancers. In spite of the rich vascularity of the organ, penile metastases are uncommon. Cutaneous metastasis of urothelial carcinoma (UC) is extremely rare and generally accepted as the late manifestation of a systemic spread. By 1998, approximately 500 cases of penile metastasis had been reported worldwide. However, only few case reports and series of fine-needle aspiration cytology (FNAC) of penile tumors have been documented. We report a case of penile metastasis from UC diagnosed by FNAC and describe the cytomorphological findings with an emphasis on cercariform cells. Although not commonly used, FNA of penile nodules can be effective in diagnosing recurrence or metastasis and avoiding surgical procedures, thus being an excellent initial procedure in the diagnostic approach.

scholarly journals Primary infradiafragmatic bony classical Hodgkin lymphoma

2020 ◽  
Vol 3 (4) ◽  
pp. 94-95
Author(s):  
Fariba Binesh ◽  
◽  
Reza Nafisi Moghadam ◽  
Mohammad Reza Vahidfar ◽  
Ehsan Amiri ◽  
...  
Keyword(s):  
Hodgkin Lymphoma ◽  
Case Reports ◽  
Pelvic Bone ◽  
Lytic Lesion ◽  
Classical Hodgkin Lymphoma ◽  
Open Biopsy ◽  
Clinical Expression ◽  
Classic Hodgkin Lymphoma ◽  
Primary Bone ◽  
Peculiar Case

Infradiaphragmatic Hodgkin’s lymphoma (IDHL) is a scarce neoplasm and primary pelvic bone exhibition is limited to case reports. Recognition and management of likewise a rare disease are challenging. Here the authors present a peculiar case of classic Hodgkin lymphoma (CHL) of pelvic bone. A 31year-old man was admitted to our hospital with chief complaint of left hip pain. Imaging showed a lytic lesion in the left iliac bone with sclerotic margin and extension to soft tissue. Open biopsy confirmed the diagnosis of CHL. CHL at first introducing as pelvic bone involvement is really uncommon. The diagnosis of primary bone CHL should be made by tough histological and clinical expression.

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