scholarly journals Effectiveness and safety of a combination of sun protection and depigmentation agent in the treatment of epidermal hyperpigmentation

2021 ◽  
Vol 7 (3) ◽  
pp. 400
Author(s):  
B. S. Chandrashekar ◽  
Vinay N.
Keyword(s):  
Skin Color ◽  
Treatment Effectiveness ◽  
Medication Compliance ◽  
Compliance Rate ◽  
Public Health Problem ◽  
Treatment Compliance ◽  
Sun Protection ◽  
Melanin Index ◽  
Modality Approach ◽  
Grade 3

<p class="Default"><strong>Background: </strong>Medication adherence is recognized as a worldwide public health problem. As a multi-modality approach with sun protection and depigmentation is quintessential in patients with epidermal hyperpigmentation, a combination of day and night cream may be prudent for long-term improvement and compliance. Aim of the current investigation was to assess treatment outcomes and medication compliance in patients with epidermal hyperpigmentation using day and night cream in a combi-kit packaging (Melaglow day and night<sup>TM</sup> combi-kit).</p><p><strong>Methods: </strong>Sixty patients (18-45 years) with epidermal pigmentation were enrolled in this 12-week study. Treatment effectiveness was determined by melanin index/erythema measure (dermacatch), extent, depth and density of pigmentation (fotofinder), and clinical/dermoscopic aspects (grade-1: &lt;25%; grade-2: 25%-50%; grade-3: 50%-75%; grade-4: &gt;75% reduction in the amount of epidermal pigment), safety, satisfaction, and compliance were assessed.</p><p><strong>Results: </strong>Out of 60 patients, 52 completed the study. The overall percentage of melanin and erythema improvement was 22.51% and 13.85%, respectively. Based on fotofinder images, 36.54% had grade-2, 34.62% had grade-3, 15.38% had grade-1, and 13.46% patients had grade-4 improvement. Based on the photographic images, 40.38% had grade-2, 32.69% had grade-3, 17.31% had a grade-1, and 9.62% had grade-4 improvement in skin color. All patients agreed that combi-kit helped in remembering and adhering to treatment. Most patients were satisfied with the treatment (84.62%), with compliance rate of 97.72%. No adverse events were reported.</p><p><strong>Conclusions:</strong> Combi-kit containing day and night cream (Melaglow day and night<sup>TM</sup> combi-kit) was safe and effective in the treatment of epidermal pigmentation, ensuing treatment compliance, and patient satisfaction. <strong></strong></p>

scholarly journals Sun Protection and Sunburn in Children Aged 1–10 Years in Germany: Prevalence and Determinants

Children ◽  
2021 ◽  
Vol 8 (8) ◽  
pp. 668
Author(s):  
Tatiana Görig ◽  
Corinna Södel ◽  
Annette B. Pfahlberg ◽  
Olaf Gefeller ◽  
Eckhard W. Breitbart ◽  
...  
Keyword(s):  
Role Models ◽  
Skin Color ◽  
Role Model ◽  
Sun Protection ◽  
Minor Role ◽  
Positive Role ◽  
Protection Measures ◽  
Telephone Interviews ◽  
The Past ◽  
A Minor

Seeking shade, the use of textile sun protection and sunscreen, and protecting one’s eyes by wearing sunglasses are recommended sun protection measures in children. We aimed to quantify the use of these measures as well as the prevalence of sunburn in children aged 1 to 10 years in Germany and to identify their determinants. Data collected via telephone interviews in a nationwide sample of 554 parents or caregivers in family were analyzed. Use of sunscreen was the most common measure applied (77.8%), while sunglasses were least frequently used (12.5%). The prevalence of sunburn during the past year was 21.8%, and it was positively associated with children’s age. The use of sun protection measures was significantly associated with the age and skin color of the child, while characteristics and tanning behaviors of the caregivers only played a minor role. The use of sun protection measures was higher when caregivers perceived themselves as a role model (Odds Ratio (OR) = 4.33, p < 0.001). Our nationwide data show that there remains a need for the improved use of sun protection measures, especially in children aged 7 to 10 years. In educational material, parents should be encouraged to become positive role models for their children regarding sun protection.

Erratum

PEDIATRICS ◽  
1989 ◽  
Vol 84 (4) ◽  
pp. 612-612
Keyword(s):  
Ultraviolet Light ◽  
Skin Color ◽  
Social Norm ◽  
Sun Exposure ◽  
Sun Protection ◽  
Social Perceptions ◽  
Increased Risk ◽  
Ineffective Efforts ◽  
Per Se

In the commentary, "Sunburns, Melanoma, and the Pediatrician," by Williams and Sagebiel (Pediatrics 1989;84:381-382), three lines were omitted from the bottom of p 381. The whole paragraph is reprinted here. It is clear that a change is required in social perceptions in which a suntan is equated with health and beauty—not because suntans per se are unhealthy (the deleterious effects of ultraviolet light at suberythemogenic levels are not wellestablished), but because the persistent and often futile efforts of those who constitutionally have less pigment to achieve a tan have serious long-term health consequences. Ideally, there should be a social norm of beauty in which the natural differences in skin color are appreciated and black, tan, pink, and all shades in between are celebrated. Similarly, we need to change our thinking about freckles and solar lentigines. These are not "cute" but represent the ineffective efforts of melanocytes in genetically underpigmented skin to provide protective pigmentation in response to solar stress. Although pediatricians alone cannot change social concepts of beauty, we can instruct our patients and their families about sun protection and we can monitor them for early signs of excessive sun exposure. Weinstock et al demonstrated an increased risk of melanoma for those who had blistering sunburns in adolescence. Although they did not address the risk associated with sunburning prior to ages 15 years, it seems likely that these data can be applied to children of all ages. Therefore, instruction and sun protection should begin in infancy. Moreover, teenagers are known to be both highly conditioned by peer concepts of beauty and relatively impervious to the counsel of their elders. It is essential, therefore, that they enter these years with skin that has been well protected and with minds well indoctrinated.

scholarly journals Evaluation of coverage of mass drug administration programme conducted in Nalgonda district of Telangana state

2018 ◽  
Vol 5 (12) ◽  
pp. 5178
Author(s):  
Praveena Ganapa ◽  
Kishore Y. Jothula ◽  
Vishweswara Rao Guthi ◽  
P. Abhishek ◽  
V. Jyothi ◽  
...  
Keyword(s):  
Lymphatic Filariasis ◽  
Drug Administration ◽  
Mass Drug Administration ◽  
Compliance Rate ◽  
Public Health Problem ◽  
Control Programme ◽  
Major Public Health Problem ◽  
Endemic District ◽  
Study Population ◽  
Coverage Rates

Background: Lymphatic filariasis has been a major public health problem in India. Government of India during 2004 initiated Mass Drug Administration (MDA) with annual single dose of DEC tablets to all the population living at the risk of filariasis. Nalgonda is endemic district where MDA programme is undertaken every year to eliminate lymphatic filariasis. The present study was undertaken to evaluate the coverage and compliance rates of the MDA programme conducted during January 2018.Methods: The guidelines of National Vector Borne Disease Control Programme (NVBDCP) were used to select a total of 129 households from four clusters (three rural and one urban). Each household was visited by a team and data was recorded on pre-structured questionnaire available in operational guidelines manual of NVBDCP. Data analyzed by SPSS version 22.Results: Total of 129 households were included in the study, Among the 523 study population, only 494 were eligible population to receive MDA. Current study shows that coverage rate was 79.84% and compliance rate was 84.6%. Fear of side effects was most common reason for noncompliance.Conclusions: Efforts should be made to improve coverage rates by involving more human resources, supervision and incentives. Though compliance rates were higher than required there is need to maintain these rates by IEC activities and community participation. 

Abstract TMP99: Farmalarm: App for Mobile Devices Improves Risk Factor Control After Stroke

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Marc Ribo ◽  
Estefania montiel ◽  
Estela Sanjuan ◽  
Mireia Sanchis ◽  
Marta Rubiera ◽  
...  
Keyword(s):  
Risk Factors ◽  
Risk Factor ◽  
Medical Staff ◽  
Healthy Lifestyle ◽  
Medication Compliance ◽  
Treatment Compliance ◽  
Lifestyle Changes ◽  
Stroke Patients ◽  
Risk Factor Control ◽  
Stroke Awareness

Risk factor control and treatment compliance in the following months after stroke are often poor. We aim to validate a digital platform for smartphones designed to raise awareness in patients about the need to perform healthy lifestyle changes, improve communication with medical staff and increase treatment compliance Methods: Farmalarm is an app for smartphones designed to increase stroke awareness by: medication visual alerts and compliance control, chat communication with medical staff, sharing didactic video files, exercise monitoring... Stroke patients discharged home were screened for participation and divided in two groups: to follow the FARMALARM program during 3-4 weeks or standard of care follow-up. We determined risk factor control goals at 90 days in all patients Results: During 16 months, from the 457 patients discharged home, 126 (27.6%) were included in the study: Farmalarm n=74; age 57±12, Control n=52, age 59±10. There were no significant differences in baseline characteristics between groups. Patients in Farmalarm group followed the program for 23±6 days after discharge. In Farmalarm group, mean number alarms due to medication intake failure dropped from 68.5% in the first week to 44.6% in the third week (p=0.03). At 90 days, achievement of risk factor control was higher in the FARMALARM group (table). The rate of patients with 4/4 risk factors under control was higher in the FARMALARM group (45.3% Vs 22.5%; p=0.02) (graph) and less patients dropped all medications at 3 months in the Farmalarm group (1.5% Vs 8.16%:p=0.05). A regression model adjusted for age and gender showed that the only variable independently associated with all risk factors under control at 90 days was the use of Farmalarm (OR: 4.7; 95% CI:1.1-6.9;p=0.03). Conclusion: In stroke patients discharged home the use of mobile applications to monitor medication compliance and increase stroke awareness is feasible and seems to improve the control of vascular risk factors.

Postoperative treatment compliance rate and complications with two different protocols after pterygium excision and conjunctival autografting

2020 ◽  
pp. 112067212091733
Author(s):  
Noelia Sabater-Cruz ◽  
Marina Dotti-Boada ◽  
José Rios ◽  
Maria Teresa Carrion ◽  
Lillian Chamorro ◽  
...  
Keyword(s):  
Postoperative Complications ◽  
Ocular Hypertension ◽  
Intraoperative Complications ◽  
Compliance Rate ◽  
Treatment Compliance ◽  
Postoperative Treatment ◽  
First Year ◽  
Topical Steroids ◽  
Pterygium Excision ◽  
Conjunctival Autografting

Aim: To evaluate compliance rate to pterygium postoperative treatment with two different protocols. Methods: Review of clinical data of patients submitted to pterygium excision and conjunctival autografting in a single centre (and a single surgeon) in Barcelona between March 2014 and December 2017. Initial postoperative protocol (protocol 1) consisted of 4 months of topical steroids in a tapering fashion. Protocol 2 consisted of topical steroids tapered over 5 weeks. Compliance rate, complications and clinical outcomes were evaluated, and statistical comparisons were made. Results: 120 surgeries were performed in 99 patients. Protocol 1 was applied in 63 cases and the next 57 followed protocol 2. Compliance with protocol 1 (57.6%) was lower than with protocol 2 (84.9%) (p = 0.002). Intraoperative complications (graft tear, corneal thinning, corneal perforation and bleeding) were found in 10 cases of protocol 1 and three cases of protocol 2, p = 0.08. Postoperative complications (graft dislocation, graft haematoma, ocular hypertension and recurrence) were found in 31 cases of protocol 1 (46.2%) and eight cases of protocol 2 (14%), p = 0.001. Six weeks after surgery, ocular hypertension was detected in eight cases corresponding to protocol 1 (13.6%) and two cases of protocol 2 (3.8%), p = 0.099. Recurrence rate during first year was higher in protocol 1 (26.3%) compared to protocol 2 (7.6%), p = 0.011. No cases of visual acuity worsening or infection were registered. Conclusion: Protocol 2 has shown to have higher compliance rate than protocol 1 and less postoperative complications, proving to be a safe and effective postoperative treatment after pterygium surgery.

scholarly journals P03.11 Finding a predictive marker for compliance to TTFields therapy - the comptune study

2019 ◽  
Vol 21 (Supplement_3) ◽  
pp. iii27-iii27
Author(s):  
M A Proescholdt ◽  
A Haj ◽  
C Doenitz ◽  
A Brawanski ◽  
A Mühlberger ◽  
...  
Keyword(s):  
Psychological Assessment ◽  
Medical Center ◽  
Treatment Success ◽  
Compliance Rate ◽  
Treatment Compliance ◽  
Observation Time ◽  
Continuous Exposure ◽  
Psychological Profile ◽  
Assessment Battery ◽  
The Individual

Abstract BACKGROUND Tumor Treating Fields (TTFields) imply the administration of alternating electric fields to induce mitotic arrest in Glioblastoma (GBM) cells. Based on the specific mode of action, which requires continuous exposure of the malignant cell pool to TTFields, compliance to TTFields treatment is a crucial parameter for treatment success. Correspondingly, a recent post hoc analysis of the EF-14 trial has demonstrated a strong correlation between TTFields compliance rate and treatment success. However, there is currently no data regarding predictive factors for individual compliance rate. We are therefore performing a prospective study designed to analyze specific parameters potentially influencing compliance to TTFields treatment employing a standardized psychological assessment battery in GBM patients who choose or not choose to undergo TTFields treatment in a longitudinal fashion. The results of the psychological profile will be correlated to the compliance rates of the individual patients. MATERIAL AND METHODS Forty adult patients treated for newly diagnosed GBM at the University Regensburg Medical Center will be recruited. The psychological assessment battery aims at assessing four categories relevant for treatment compliance: 1. Lack of communicative skills, 2. depressive and anxiety disorders, 3. interpersonal factors (e.g. social support), and 4. intrapersonal factors, (e.g. beliefs about benefit, self-efficacy). The study endpoints are: 1. willingness to undergo TTFields therapy and 2. compliance rate of the individual patient, provided by the technical support team. The first interview takes place after treatment consultation (T0), 2 weeks after diagnosis (T1), at the initiation of TTFields treatment (T2) and every 4 weeks during treatment either until second disease progression or after maximal 8 months observation time per patient. Additionally, demographic (gender, age, marital status), clinical (KPI, extent of resection) and biological factors (MGMT promoter status, IDH1 mutation) will be assessed. RESULTS The study has been approved by the local ethics committee and has recruited the first 23 patients within 8 months since initiation of the study. The most updated results will be presented at the meeting. CONCLUSION One of the most challenging aspects in the application of TTFields in clinical practice is the identification of influencing factors increasing patients’ compliance. This study is designed to provide a psychological profile predictive for high treatment compliance.

Antihypertensive Medication Compliance in a Veterans Affairs Healthcare System

2002 ◽  
Vol 36 (6) ◽  
pp. 986-991 ◽  
Author(s):  
Amy J Wannemacher ◽  
Gregory P Schepers ◽  
Kevin A Townsend
Keyword(s):  
Healthcare System ◽  
Ace Inhibitors ◽  
Medication Compliance ◽  
Compliance Rate ◽  
Health Information System ◽  
Channel Blockers ◽  
Angiotensin Ii Receptor ◽  
Antihypertensive Medications ◽  
Β Blockers ◽  
Mean Compliance

OBJECTIVE: To compare compliance rates associated with categories of antihypertensive medications in a Veteran's Affairs (VA) Healthcare System by use of readily available data and standard software. METHODS: Prescriptions from the Veteran's Health Information System Technology Architecture (VISTA) database for angiotension-converting enzyme (ACE) inhibitors, angiotensin II receptor blockers (ARBs), β-blockers, calcium-channel blockers (CCBs), diuretics, and a miscellaneous group of antihypertensives filled or refilled during a 12-month period were included in the analysis. Claims data for each prescription were exported from the VISTA database to Microsoft Excel, and compliance rates were calculated by use of a methodology reported elsewhere. Mean compliance rates for each antihypertensive category were compared. RESULTS: A total of 26 201 prescription records accounting for 51 927 separate prescription fills or refills were included. The majority of prescriptions (77%) were associated with calculated compliance rates >80%. The CCB category was associated with a significantly higher compliance rate (p < 0.001) than the β-blockers (95% CI 1.3% to 3.7%), diuretics (95% CI 1.4% to 3.8%), and miscellaneous agents (95% CI 1.7% to 7.5%). The ACE inhibitor category was associated with a significantly higher rate (p < 0.001) than the β-blockers (95% CI 0.7% to 3.0%), diuretics (95% CI 0.7% to 3.0%), and miscellaneous agents (95% CI 1.1% to 6.8%). The ARB category had a higher compliance rate (p < 0.001) than the miscellaneous category (95% CI 1.2% to 11.9%). There were no significant differences in compliance rates among ACE inhibitors, CCBs, or ARBs. CONCLUSIONS: VA outpatients are relatively compliant when taking their antihypertensive medications as measured by prescription refill rates. Compliance rates for CCBs and ACE inhibitors are higher than those for β-blockers, diuretics, and agents such as clonidine, methyldopa, hydralazine, and reserpine. Compliance for ARBs compared favorably with those of CCBs and ACE inhibitors. The methods used in this evaluation can be easily implemented at other institutions as part of ongoing medication compliance improvement efforts.

A Study of Skin Color by Melanin Index according to Sex, Age, Site and Skin Phototype in Koreans

2002 ◽  
Vol 14 (2) ◽  
pp. 71 ◽  
Author(s):  
Mu Hyoung Lee ◽  
Tuk Woo Lim ◽  
Mu Hyoung Lee
Keyword(s):  
Skin Color ◽  
Melanin Index ◽  
Skin Phototype

scholarly journals Assessment of the relationship between depression and treatment compliance in chronically-ill patients in Jeddah, Saudi Arabia

2021 ◽  
Vol 20 (1) ◽  
pp. 177-182
Author(s):  
Ameen Mosleh Almohammadi ◽  
Somayah Saeed Bawazeer ◽  
Joud Jamal Balkhair ◽  
Aroub Adel Rajab
Keyword(s):  
Medication Compliance ◽  
Treatment Compliance ◽  
Chronically Ill ◽  
Lifestyle Changes ◽  
Inverse Association ◽  
Mild Depression ◽  
Cross Sectional ◽  
Adherence To Medication ◽  
Chronically Ill Patients ◽  
The Relationship

Purpose: To find the relationship between depression, treatment adherence and lifestyle changes inchronically-ill patients residing in Jeddah, Saudi Arabia.Methods: A cross-sectional study was conducted. A self-administered questionnaire was used tocollect data from patients of multi-healthcare centers located in Jeddah. The questionnaire aimed tocollect the information regarding patients’ levels of medication compliance, patients’ capacity to copewith the disease and adherence to medication, along with their depression level.Results: Of the overall sample size of 439 patients, 43.1 % were suffering from hypertension, 37.8 %were diabetic and 33.7 % had hyperlipidemia. Besides, total scores of Patient Health Questionnaire-9(PHQ-9) showed that approximately 5 % patients were severely depressed, 8 % had moderately severedepression, 27 % had moderate depression, and 60 % had mild depression. Compliance scale datarevealed that 38 % patients showed low compliance, 51 % showed partial compliance, and 11 %showed high compliance. Also, a significant inverse relationship between depression and compliancescales (rs = -0.221, p = 0.004) was observed.Conclusion: The results show an inverse association between depression and medication adherencein patients with chronic disease in Jeddah. Therefore, clinicians are advised to assess the level ofdepression in chronically-ill patients in order to improve their adherence to medicine.Keywords: Chronic illness, Depression, Medication adherence, Treatment compliance

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