scholarly journals Seroprevalence of Toxocara Infection among Asthmatic Children in Shiraz City, Southern Iran

2021 ◽  
Author(s):  
Amir Masoud Salemi ◽  
Nasir Arefkhah ◽  
Fattaneh Mikaeili ◽  
Hamed Rabbani ◽  
Hesamodin Nabavizadeh
Keyword(s):  
Rural Areas ◽  
Toxocara Canis ◽  
Large Sample Size ◽  
Healthy Children ◽  
Serum Samples ◽  
Asthmatic Children ◽  
Asthmatic Patients ◽  
Southern Iran ◽  
Significant Difference ◽  
Urban And Rural Areas

Background: Human toxocariasis is caused by Toxocara canis and T. cati, the nematodes in the intestine of dogs and cats, respectively. Since the association between asthma and toxocariasis is controversial, the aim of the present study was to investigate the seroprevalence of Toxocara infection among asthmatic children in comparison with healthy children. Methods: This case-control study was conducted on 92 asthmatic and 91 healthy children aged 1-16 years old in Shiraz City, Southern Iran in 2019-2020. The serum samples were tested for IgG anti-Toxocara antibodies by ELISA method using the T. canis larval excretory-secretory (E/S) antigens. The collected data were analyzed using SPSS software. Results: The seroprevalence of toxocariasis in asthmatic patients was higher than the healthy children with no significant difference in Toxocara seropositivity between two groups (9.8% vs 8.8%, P = 0.817). The association between Toxocara infection and variables such as gender and age were not statistically significant. Conclusion: There was no significant association between toxocariasis and childhood asthma. Further study on different regions such as urban and rural areas with a large sample size and using questionnaire for considering risk factors of asthma and toxocariasis is recommended.

Voice analysis and vocal cord assessment in asthmatic children

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
E A Zaky ◽  
E M Fouda ◽  
H A Eldesouky ◽  
A S Abdhakeem
Keyword(s):  
Asthma Control ◽  
Vocal Folds ◽  
Control Group ◽  
Healthy Children ◽  
Voice Analysis ◽  
Abnormal Finding ◽  
Asthmatic Children ◽  
Asthmatic Patients ◽  
Significant Difference ◽  
And Control

Abstract Aim of work This is a cross sectional case control study to asses vocal folds abnormalities and voice analysis in asthmatic children to detect subclinical changes and to correlate them with their various clinical and functional grading and level of control. Methods the study included 48 asthmatic children (34 males and 14 females ) regularly attending Pediatric chest Clinic, Ain Shams university for follow up.Their median age was 7.8 years ± 2.15 IQR. A 12 age and sex matched healthy children were chosen as control group. For all patients and control the following were done: history taking,General and chest examination, Spirometry Pulmonary functions(FEV1,FVC,), videolaryngoscopy (VLS)and Multidimensional voice analysis (MDVA) . Results VideoLaryngoscopy (VLS) of asthmatic patients showed different abnormalities in 26 cases ( 54.2% ).eg Phonatory west 1mm from the middle line(4 cases), Bilateral vocal folds nodules (4 cases), Bilateral thickening of both vocal folds(3 cases), Vocal fold cyst.(4 cases). Asthmatic children with abnormal finding in (VLS) had a statistical significant lower values of FEV1 and MMEF with higher percentage of poor asthma control. Voice analysis showed impairment of voice acoustics in asthmatic children with significant difference between asthmatic and control as regards voice analysis data with significant higher jitter and shimmer dB (measure of voice amplitude and detector of early hoarseness of voice) . Conclusion Asthmatic patients may have an associated Laryngeal or vocal folds abnormalities which are considered a comorbid condition and one of the causes of poor asthma control. Voice analysis may help in detection of subclinical hoarseness of voice which may be sequelae of chronic cough or side effects of inhaled steroids.

scholarly journals Detection of Specific Antibody Reactivity to Toxocara Larval Excretory-secretory Antigens in Asthmatic Patients (5-15 Years)

2016 ◽  
Vol 10 (1) ◽  
pp. 162-167 ◽  
Author(s):  
Mahdi Mosayebi ◽  
Latif Moini ◽  
Reza Hajihossein ◽  
Mojtaba Didehdar ◽  
Zahra Eslamirad
Keyword(s):  
Fruits And Vegetables ◽  
Toxocara Canis ◽  
Personal Hygiene ◽  
Enzyme Linked Immunosorbent Assay ◽  
Control Group ◽  
Toxocara Cati ◽  
Serum Samples ◽  
Cross Sectional ◽  
Asthmatic Children ◽  
Asthmatic Patients

Background & Purpose: Humans act as an intermediate host for Toxocara canis and Toxocara cati. Toxocara may be an important risk factor for asthma in humans. The aim of the present study was to evaluate immunoglobulin G (IgG) anti-Toxocara canis antibody, using enzyme-linked immunosorbent assay (ELISA) in asthmatic patients (aged 5-15 years), referring to a clinic of pulmonary diseases in Arak, Iran. Materials & Methods: In this bi-group cross sectional study, serum samples were collected from 110 children with confirmed asthma and 70 children without asthma within one year. IgG anti-Toxocara antibody was detected via ELISA method. The collected data were analyzed, using SPSS. Results: The seroprevalence of antibodies against Toxocara species was estimated at 1.8% (two males) in asmathic children via ELISA method; however, no antibodies against Toxocara canis were detected in the control group. There was no significant correlation between the frequency of antibodies against Toxocara and variables such as age, gender, or place of residence (P>0.05). Moreover, the frequency of antibodies against Toxocara was not significantly correlated with contact with dogs, consumption of unwashed fruits and vegetables, or use of raw/undercooked sheep liver (P>0.05). Conclusion: The present study showed anti-Toxocara antibody in 1.8% of asthmatic children and determined the seroprevalence of toxocariasis in asthmatic children and adolescents in Arak, Iran. Based on the findings, the low rate of infection with Toxocara among asthmatic children may be attributed to acceptable personal hygiene and religious considerations.

scholarly journals Correlation between vitamin D serum level and total IgE in asthmatic children

2020 ◽  
Vol 12 (2) ◽  
pp. 37-45
Author(s):  
Vesna Micevska ◽  
Tatjana Jakovska Mareti ◽  
Ilija Kirovski ◽  
Olivera Jordanova
Keyword(s):  
Vitamin D ◽  
Serum Level ◽  
P Value ◽  
Healthy Children ◽  
Total Ige ◽  
Asthmatic Children ◽  
Significant Difference ◽  
Children With Asthma ◽  
The Mean ◽  
Chronical Disease

Asthma is a chronical disease of the airways characterized by reversible obstruction of the bronchi and airway inflammation. In recent decades, the scientific interest of the vitamin D system and its role in development of asthma and other alergic diseases has been increased. Aims of this study are to mesure and compare the serum level of 25 OHD in asthmatic and healthy children and corelate the level of 25OHD and total IgE in asthmatic children. This prospective study includes 70 children at age 2 to 14, of which 32 are children with diagnosed asthma and 38 healthy children. In both  of the groups the serum level of 25 OHD was measured  and by the results 18 % of the healthy children (C) and 28% of the asthma children (E) had 25OHD  deficiency, 45%  of C and 50% of E were insufficient and 37 % of C / 22% of E were with normal 25 OHD serum level. The mean level of 25OHD in C was 27,83 +/- 10,24 and in E 20,9 ng/ml +/- 10,72. The mean levels in both groups had statistic significant difference with p-value < 0,05. According to age no statistic significant difference was found in both of the groups. There was a statisticaly significant decreased serum level of 25 OHD in asthmatic females.In the examined group (children with asthma) there was a negative linear correlation (association) of the level of 25OHD and total IgE serum level with r=- 0,55  Vitamin D serum level measurements in asthma patients gives the possibility for discovering the connection between its deficiency and development of asthma symptoms.

scholarly journals Relationship of Oxidant and Antioxidant Markers to Asthma Severity in Egyptian Asthmatic Children

2017 ◽  
Vol 5 (5) ◽  
pp. 645-650 ◽  
Author(s):  
Inas R. EL-Alameey ◽  
Gihan A. Fathy ◽  
Mones M. Abu Shady ◽  
Alaa Ali ◽  
Hanan A. Fathy ◽  
...  
Keyword(s):  
Asymmetric Dimethylarginine ◽  
Strong Predictor ◽  
Predictive Biomarker ◽  
Asthma Severity ◽  
Healthy Children ◽  
Serum Concentrations ◽  
Asthmatic Children ◽  
Paraoxonase Activity ◽  
Asthmatic Patients ◽  
Anti Oxidant

BACKGROUND: Asthma is a chronic airway disease which is characterized by oxidant antioxidant imbalance with the generation of oxidative stress related mediators.AIM: The study aimed to evaluate the role of asymmetric dimethylarginine, and malondialdehyde as oxidant markers and serum paraoxonase activity as an antioxidant marker in asthma, and to determine their relationship to the asthma severity and lung function among asthmatic children in Egypt.PATIENTS AND METHODS: This case control study was conducted on sixty patients with asthma compared with sixty apparently healthy children of matched age and sex.RESULTS: Serum concentrations of oxidant markers as asymmetric dimethylarginine and malondialdehyde were significantly increased in asthmatic patients while anti-oxidant marker as paraoxonase activity was significantly decreased compared to healthy controls (P < 0.05). ANOVA test revealed highly significant elevation of the serum concentrations of oxidant markers while anti-oxidant marker was significantly decreased in severe asthmatic patients (P < 0.001) compared to the patients with moderate and mild asthma respectively. Serum malondialdehyde concentration was a strong predictor of asthma severity by multiple regression analysis (P < 0.05).CONCLUSION: The study revealed an imbalance between oxidative and antioxidant defence systems in asthmatic children. Serum concentration of malondialdehyde was the most predictive biomarker having a significant association with asthma severity.

scholarly journals Determinants of Marriage Stability among Married Couples in North-Central Nigeria Implication for Counselling

2017 ◽  
Vol 4 (3) ◽  
pp. 356
Author(s):  
Anna Onoyase Ph.D
Keyword(s):  
Rural Areas ◽  
Married Couples ◽  
Field Work ◽  
Medical Assistance ◽  
North Central ◽  
Significant Difference ◽  
Marriage Stability ◽  
Urban And Rural Areas ◽  
Level Of Significance ◽  
Research Assistants

<em><em>The study investigated determinants of marriage stability among married couples in North Central Nigeria. In order to carry out this study, four hypotheses were formulated. An instrument known as “Determinants of Marriage Stability Questionnair (DOMSQ)” was constructed by the researcher and used to collect information from the field. The instrument had content and facial validity and its reliability coefficient is 0.87. The investigator used eight research assistants to administer nine hundred and ninety copies of the questionnaire on the respondents in Kogi and Benue States. Nine hundred and eighty three copies were retrieved from the respondents indicating 99.3 percent return rate. The researcher collated the information got from the field work and the Z statistics was used to test the hypotheses at 0.05 level of significance. The findings showed that, there was no significant difference between male and female married couples in their identification of childlessness as determinant of marriage stability, there was no significant difference between married couples in the urban and rural areas in their identification of sexual satisfaction as determinant of marriage stability, there was no significant difference between old and young married couples in their identification of cultural background as determinant of marriage stability, there was no significant difference between married couples from Kogi and Benue States in their identification of communication as determinant of marriage stability. One of the recommendations is that couples who are faced with the problem of childlessness should seek medical assistance and also be positive about such outcome.</em></em>

scholarly journals THE IMPACT OF ASTHMAAND ITS MEDICATIONS ON DENTAL CARIES STATUS AND STREPTOCOCCUS MUTANS COUNT IN CHILDREN: A CROSS-SECTIONAL STUDY

2020 ◽  
pp. 20-23
Author(s):  
Sneha Upadhyay ◽  
Jyoti Bhavthankar ◽  
Mandakini Mandale ◽  
Nivedita Kaorey
Keyword(s):  
Dental Caries ◽  
Streptococcus Mutans ◽  
Cross Sectional Study ◽  
Control Group ◽  
Healthy Children ◽  
Sectional Study ◽  
Cross Sectional ◽  
Asthmatic Children ◽  
Significant Difference ◽  
The Impact

Background: Asthma and its medications have been linked to oral diseases in asthmatic children. Aim: Assessment of the dental caries status, salivary Streptococcus mutans count and S. mutans colony score in children receiving inhaled anti asthmatic medications and their comparison in healthy children Material and Method: A cross-sectional study was performed on 40 asthmatic children and 40 healthy children in the age group of 6-14 years. DMFT/deft indices were calculated and saliva samples were collected. Diluted saliva was inoculated on MSB agar plates. S. mutans count and colony score were analysed after 24-48 hours of inoculation. Results: Statistically significant difference was observed in the mean DMFT/deft index, salivary S. mutans load and S. mutans colony score in children of the asthmatic group and control group. Conclusion: Prevalence of dental caries and cariogenic bacteria is higher in asthmatic children.

The Evaluation of the Awareness, Attitude and Practice of the Elderly Toward Self-Medication: A Cross-Sectional Study

Drug Research ◽  
2018 ◽  
Vol 68 (08) ◽  
pp. 475-480
Author(s):  
Mohammad Heidari ◽  
Mansureh Borujeni ◽  
Mansour Ghafourifard ◽  
Rahim Sheikhi
Keyword(s):  
Rural Areas ◽  
The Elderly ◽  
Cross Sectional Study ◽  
Average Score ◽  
Self Medication ◽  
Cross Sectional ◽  
Attitudes And Practices ◽  
Age Related ◽  
Significant Difference ◽  
Urban And Rural Areas

Abstract Introduction The prevalence of various diseases in the elderly has increased the use of drugs, which is coupled with age-related physiological changes and places the elderly at risk for multiple side effects. The present study aimed to determine awareness, attitudes and practices of elderly towards self-medication. Materials and Methods The sample included 300 participants over 60 years under any of the health centers in urban and rural areas of Abadeh city, who were selected based on stratified random sampling method. In order to collect data, the questionnaire including demographic information, awareness, attitude and performance of the elderly and the checklist of drug intractable consumption. Results Based on the results, 76% of the elderly reported drug consumption. Regarding lifestyle, the average score of the elderly’s awareness for the elderly who lived with and without families were 78.6±14.2 and 69.2±13.6, respectively. In other words, a significant difference was observed between these two groups. In addition, there was a significant between the elderly’s performance score with and without family members about the self-medication (p=0.001). Conclusion Considering the increase in self-medication among the elderly, adherence to prescription criteria for drug among this age group is recommended. Finally, designing and implementing various educational programs in health education center is necessary for the elderly and their families for the purpose of improving awareness and practice.

Mediterranean diet adherence rates in Sicily, southern Italy

2013 ◽  
Vol 17 (9) ◽  
pp. 2001-2009 ◽  
Author(s):  
Giuseppe Grosso ◽  
Stefano Marventano ◽  
Gabriele Giorgianni ◽  
Teodoro Raciti ◽  
Fabio Galvano ◽  
...  
Keyword(s):  
Mediterranean Diet ◽  
Rural Areas ◽  
Southern Italy ◽  
Nutrient Intakes ◽  
Cross Sectional ◽  
Significant Difference ◽  
The Mediterranean ◽  
Urban And Rural Areas ◽  
Traditional Patterns ◽  
Low Educated

AbstractObjectiveTo assess adherence to the Mediterranean diet and nutrient intakes in a population of Sicily, southern Italy and to evaluate possible determinants, particularly socio-cultural and lifestyle factors.DesignCross-sectional.SettingUrban and rural areas of eastern Sicily.SubjectsBetween May 2009 and December 2010, 3090 adults were randomly recruited through the collaboration of fourteen general practitioners. Adherence to the Mediterranean diet was measured by the MedDietScore. Nutrient intakes were assessed through the 24 h recall of the previous day's dietary intake.ResultsRural participants were barely more adherent to the Mediterranean diet than their urban counterparts (mean scores were 27·8 and 27·2, respectively, P = 0·037). The MedDietScore was correlated with intakes of MUFA, fibre and vitamin C, as well as with consumption of non-refined cereals, vegetables, fruit, meat, dairy products, alcohol and nuts. Regression analysis revealed that older and more educated people were more likely to be in the highest tertile of MedDietScore (OR = 1.90; 95 % CI 1·39, 2·59 and OR = 1·29; 95 % CI 1·05, 1·58, respectively). A significant difference in quantity (moderate) and quality (red wine and beer) of alcohol was found according to adherence to the Mediterranean diet. Finally, more active participants were 1·5 times more likely to form part of the high-adherence group.ConclusionsA slow but concrete moving away from traditional patterns has been observed in younger people and low educated people. Public health interventions should focus on these target populations in order to improve the quality of their diet.

scholarly journals AsymptomaticLeishmaniaInfected Children: A Seroprevalence and Molecular Survey in a Rural Area of Fars Province, Southern Iran

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Akram Layegh Gigloo ◽  
Bahador Sarkari ◽  
Zahra Rezaei ◽  
Gholam Reza Hatam ◽  
Mohammad Hassan Davami
Keyword(s):  
Rural Area ◽  
Buffy Coat ◽  
Seroprevalence Rate ◽  
Fars Province ◽  
Healthy Children ◽  
Serum Samples ◽  
Southern Iran ◽  
Negative Findings ◽  
And Gender ◽  
And Control

The current study aimed to evaluate the seroprevalence of visceral leishmaniasis in asymptomatic healthy children in a rural area of Fars province, Southern Iran. Blood samples were taken from 617 asymptomatic healthy children and serum samples along with buffy coat were separated from the blood. The serum samples were assessed for antibodies againstLeishmania infantumby an indirect ELISA and the buffy coats were tested for the presence ofL. infantumDNA by molecular method. Of the 617 recruited children, 297 (48.1%) were female and 317 (51.4%) were male. Anti-Leishmaniaantibodies were detected in 17 (2.8%) of the children. From those 17 seropositive cases, 5 (29.4%) were male and 12 (70.6%) cases were female. Children aged 5–8 years had the highest seroprevalence rate; however, no associations were found between seropositivity toLeishmaniaand gender or age of the children. Moreover,L. infantumDNA was detected in buffy coat of 8 (1.3%) of 617 children. Three of the PCR-positive cases were seropositive whereas 14 of seropositive subjects (82.3%) were PCR-negative. Findings of the current study revealed a considerable subclinical leishmanial infection in children in the studied rural area in the south of Iran. Results of the current study could be used for surveillance, prevention, and control of VL in the area.

INCIDENCE AND PREVALENCE OF VARIOUS PSYCHIATRIC DISORDERS IN PSYCHIATRIC DEPARTMENT OF TEACHING BASED HOSPITAL ONGOLE: A PROSPECTIVE OBSERVATIONAL STUDY

2020 ◽  
pp. 11-24
Author(s):  
T. Josna T. Josna ◽  
N. Rajesh N. Rajesh ◽  
K. Naga Sindhura K. Naga Sindhura ◽  
K. Hema Ravali K. Hema Ravali ◽  
N. Uma Jyothi N. Uma Jyothi ◽  
...  
Keyword(s):  
Mental Disorders ◽  
Psychiatric Disorders ◽  
Rural Areas ◽  
Epidemiological Studies ◽  
Chi Square ◽  
Significant Difference ◽  
Chi Square Test ◽  
Urban And Rural Areas ◽  
Chi Square Analysis ◽  
Psychiatric Department

Background: Psychiatric disorders are known to vary across time within the same population and also vary across populations. Most of the community-based Indian epidemiological studies are on point prevalence. The adult epidemiological finding that mental disorders have early ages of onset has created interest in the minds of psychiatrists. Children and adolescents are at high risk of developing mental disorders. Aim & objective: we are aimed at to conduct of this study was to know the overall incidence and prevalence rate of various Psychiatric disorders in the Psychiatric department of teaching based hospitals and the objective of the study is to find out the incidence and prevalence of the predominant psychiatric disorder. To find the role of key factors like age, Education, Gender, environmental analysis, Marital status, and sleep pattern on the mental health status of Patients. Material & Methods: This study was conducted on 500 patients, both male and female were included in the study. ICD- 10 and DSM IV criteria tools were used. Statistical Analysis was done using appropriate tests like the “t” test and Chi-Square test. Results: A total of 500 Patients we are included in our study, males are 293(59%) and Females are 207 (41%). Depression shows the highest incidence of 7.0%. Schizophrenia shows the highest prevalence (17.6%) Chi-Square analysis indicated no significant difference in prevalence between the number of males and females.  There were no significant differences among the prevalence rates among the participants who belonged to middle-class urban and rural areas. Conclusion: Psychology is the science of behavior and mind, it intends to surmise clinical individuals and groups via placing general principles and researching specific cases. As a responsible clinical pharmacist, we have played a major role in the effective counseling of patients by using counseling aids. In this research, have a leading prevalence plus incidence of psychiatric disorders are detected.

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