scholarly journals Dietary Food Groups and Nutrient Intake in Association with Multiple Sclerosis: A Case-Control Study

2021 ◽  
Author(s):  
Monire Fallah Yakhdani ◽  
Mohammad Mohammadi ◽  
Amin Salehi Abargouei ◽  
Masuod Mirzaei ◽  
Abolghasem Rahimdel ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Case Control Study ◽  
Economic Status ◽  
Sun Exposure ◽  
Case Control ◽  
Dietary Intakes ◽  
Food Groups ◽  
Yazd City ◽  
The Relationship ◽  
Control Study

Introduction: It has been proposed that dietary intake is associated with multiple sclerosis (MS). The present case-control study was conducted to investigate the relationship between intake of different food groups and occurrence of MS among the recently diagnosed adult patients in Yazd City, Iran. Materials and Methods: In the current study, a group of 45 patients who have recently been diagnosed with MS and 100 healthy controls were investigated in this research. Participants were matched regarding their gender. Dietary intakes were assessed using a self-administered semi-quantitative food frequency questionnaire (FFQ). Participants also completed a demographic questionnaire including information such as age, gender, marital status, job, education, sun exposure, smoking, sunscreen, body mass index (BMI), economic status, as well as their spouses' occupations and education. Logistic regressions in crude and multivariable-adjusted models were used to investigate the relationship between food groups and the odds of developing MS. Results:  The findings showed that participants with high consumption of fruits, potatoes, refined grains, pickles, and fibers had a significantly lower chance for developing MS after adjustment for the maximum possible confounding variables (P < 0.05). Conclusion: The present study revealed that several food groups or nutrients are associated with the development of MS.  Further multi-central prospective studies including more participants are needed to confirm these results

Multiple sclerosis and solar exposure before the age of 15 years: case—control study in Cuba, Martinique and Sicily

2010 ◽  
Vol 16 (8) ◽  
pp. 899-908 ◽  
Author(s):  
F. Dalmay ◽  
D. Bhalla ◽  
A. Nicoletti ◽  
JA Cabrera-Gomez ◽  
P. Cabre ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Case Control Study ◽  
Sun Exposure ◽  
Protective Role ◽  
Case Control ◽  
Solar Exposure ◽  
History Of ◽  
Water Sports ◽  
Control Study

Few studies report a protective role of childhood solar exposure to multiple sclerosis. Our objective was to confirm the protective role of childhood solar exposure in multiple sclerosis in Cuba, Martinique and Sicily. This was a matched case— control study, and cases met Poser criteria for clinically, laboratory (definite, probable) multiple sclerosis. Controls were resident population, without neurological disorder, living close to cases (within 100 km), matched for sex, age (±5 years), residence before age 15. We recruited 551 subjects during a 1-year period (193 cases, Cuba n = 95, Sicily n = 50, Martinique n = 48; 358 controls). Some (89%) met definite clinical multiple sclerosis criteria (relapsing remitting form (with and without sequel) (74%), secondary progressive (21%), primary progressive (5%)). Odds ratios in a uni-variate analysis were: family history of multiple sclerosis (5.1) and autoimmune disorder (4.0); wearing shirt (3.5), hat (2.7), pants (2.4); sun exposure causing sunburn (1.8); sun exposure duration (1 h more/day; weekends 0.91, weekdays 0.86); bare-chested (0.6); water sports (0.2). Independent factors in the multivariate analysis were family history of multiple sclerosis (4.8 (1.50—15.10)), wearing pants under sunlight (1.9 (1.10—3.20)), sun exposure duration (1 h more/ day, weekdays 0.90 (0.85—0.98), weekends 0.93 (0.87—0.99)), water sports (0.23 (0.13—0.40)). We conclude that outdoor leisure activities in addition to sun exposure reports are associated with a reduced multiple sclerosis risk, with evidence of dose response.

scholarly journals Frequency of HLA-DRB1 Gene Alleles in Patients With Multiple Sclerosis in a Lithuanian Population

Medicina ◽  
2012 ◽  
Vol 48 (1) ◽  
pp. 2
Author(s):  
Renata Balnytė ◽  
Daiva Rastenytė ◽  
Dalia Mickevičienė ◽  
Antanas Vaitkus ◽  
Erika Skrodenienė ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Case Control Study ◽  
Case Control ◽  
Chain Reaction ◽  
Female Patients ◽  
History Of ◽  
Male Patients ◽  
Polymerase Chain ◽  
The Relationship ◽  
Control Study

The aim of the present study was to investigate the influence of HLA-DRB1 alleles on the genetic susceptibility to multiple sclerosis in the Lithuanian population. Material and Methods. A total of 120 patients with multiple sclerosis and 120 unrelated healthy controls were enrolled in this case-control study. Allelic frequencies were compared between the groups. HLA-DRB1 alleles were genotyped using the polymerase chain reaction. Results. HLA-DRB1*15 was present in 55.8% of the patients with multiple sclerosis and 10.0% of the controls (OR, 5.58; 95% CI, 3.19–9.77; P<0.0001). The protective alleles that were found to be more prevalent among the controls compared with the patients with multiple sclerosis were HLADRB1* 01 (26.7% vs. 7.5%, P<0.0001), *03 (17.5% vs. 8.3%, P=0.034), and *16 (11.7% vs. 3.3%, P=0.014). HLA-DRB1*15 was more common among the female patients with multiple sclerosis than among the male patients (68.4% vs. 34.1%; OR, 4.18; 95%, CI 1.90–9.22; P=0.001). The heterozygous inheritance of HLA-DRB1*15 allele was more common in the patients with a history of maternal multiple sclerosis than in those with a history of paternal multiple sclerosis (29.4% vs. 9.8%; P=0.045). Conclusions. HLA-DRB1*15 was found to be associated with multiple sclerosis in the Lithuanian population. This allele was more prevalent among the female patients with multiple sclerosis. Maternal multiple sclerosis was more common than paternal multiple sclerosis, but the relationship with HLA-DRB1*15 allele was not established. HLA-DRB1*01, *03, and *16 appeared to be the protective alleles in this series.

The relationship of indoor radon gas concentration with multiple sclerosis: a case-control study

2020 ◽  
Vol 27 (14) ◽  
pp. 16350-16361 ◽  
Author(s):  
Zeynab Abaszadeh Fathabadi ◽  
Mohamad Hassan Ehrampoush ◽  
Masuod Mirzaei ◽  
Mehdi Mokhtari ◽  
Mohamad Nadi Sakhvidi ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Case Control Study ◽  
Indoor Radon ◽  
Case Control ◽  
Gas Concentration ◽  
Radon Gas ◽  
Relationship Of ◽  
The Relationship ◽  
Control Study

The relationship between dietary intakes during pregnancy and incidence of postpartum depression: a case-control study

2019 ◽  
Vol 50 (4) ◽  
pp. 751-764
Author(s):  
Shirin Amini ◽  
Sima Jafarirad ◽  
Reza Amani ◽  
Mehdi Sayyah Bargard ◽  
Bahman Cheraghian ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Case Control Study ◽  
Unsaturated Fatty Acids ◽  
Post Partum ◽  
Saturated Fatty Acids ◽  
Case Control ◽  
Dietary Intakes ◽  
Content Type ◽  
The Relationship ◽  
Control Study

Purpose Post-partum depression (PPD) is a mood disorder that affects 20-40 per cent of women in their post-delivery period worldwide. The purpose of this paper is to compare dietary intakes of energy, macronutrients, cholesterol, saturated fatty acids (SFAs), mono-unsaturated fatty acids (MUFAs), poly-unsaturated fatty acids (PUFAs), some micronutrients and antioxidants in PPD patients with healthy controls. Design/methodology/approach This case-control study was conducted on 163 women in postpartum period (81 PPD and 82 non-PPD) using Edinburgh questionnaire for the diagnosis of PPD. Dietary nutrients intake was assessed using 147-item semi-quantitative food frequency questionnaire (FFQ). Portion sizes of food items were converted to grams per day. Logistic regression models were used to estimate the association between tertiles of dietary intakes with the odds ratio (OR) of PPD. Findings According to the fully adjusted model, highest tertile compared to lowest tertile dietary intake of SFAs [OR = 0.01; 95 per cent confidence interval (CI) = 0.00, 0.01, p = 0.001], MUFAs (OR = 0.01; 95 per cent CI = 0.00, 0.02, p < 0.001), total fats (OR = 0.01; 95 per cent CI =0.00, 0.01, p < 0.001) and cholesterol (OR = 0.06 ; 95 per cent CI = 0.01, 0.08, p < 0.001), thiamine (OR = 0.01; 95 per cent CI = 0.00, 0.01, p < 0.001), riboflavin (OR = 0.10; 95 per cent CI = 0.02, 0.39, p < 0.001), pyridoxine (OR = 0.03; 95 per cent CI =0.01, 0.32, p < 0.001), folate (OR = 0.01; 95 per cent CI = 0.00, 0.01, p < 0.001), cobalamine (OR = 0.01; 95 per cent CI = 0.00, 0.01, p < 0.001) , selenium (OR = 0.79 ; 95 per cent CI =1.36, 3.32, p < 0.001), iron (OR =0.68; 95 per cent CI = 0.24, 0.94, p < 0.001) and iodine (OR = 0.36; 95 per cent CI =1.10, 1.38, p < 0.001) had a protective effect on the incidence of PPD. Furthermore, higher intake of vitamin A and beta-cryptoxanthin can increase the incidence of PPD (OR =114.29; 95 per cent CI =17.85, 118.12, p < 0.001) and (OR = 4.85; 95 per cent CI = 1.49, 15.69, p = 0.015), respectively. Originality/value PPD may have destructive effects on the relationship between mother and infant. Results of previous studies demonstrated nutrients are required for the synthesis of neurotransmitters and have biochemical role in the nervous system.

scholarly journals The relationship between rice consumption and glioma: a case–control study in adults

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Maryam Aghababaie Shahrestani ◽  
Parvane Saneei ◽  
Mehdi Shayanfar ◽  
Minoo Mohammad-Shirazi ◽  
Giuve Sharifi ◽  
...  
Keyword(s):  
Case Control Study ◽  
Disease Diagnosis ◽  
Case Control ◽  
Demographic Variables ◽  
Dietary Intakes ◽  
Age And Gender ◽  
Rice Consumption ◽  
And Gender ◽  
The Relationship ◽  
Control Study

AbstractPrevious studies have shown the effect of refined grains on various cancers; however, data on the link between rice consumption and brain cancer are scarce. We aimed to investigate the relationship between rice consumption and glioma in Iranian adults. Current hospital-based case–control study was done in Tehran between 2009 and 2011. Cases were individuals with pathologically confirmed glioma in a maximally 1 month of the disease diagnosis (n = 128). Controls were individuals, aged between 20 and 75 years, who were hospitalized or were outpatients referred to other wards of the same hospital (n = 256). Cases and controls were frequently matched in terms of age and gender. Usual dietary intakes of participants, including rice consumption, during the preceding year were examined using a Block-format validated semi-quantitative 126-item food frequency questionnaire. Compared with participants in the lowest tertile of rice consumption (< 181 g/day), those in the highest tertile (≥ 279 g/day) had 2.47 times greater chance for having glioma (OR: 2.47, 95% CI 1.44–4.23). This relationship was also seen when potential confounders including demographic variables, energy and dietary intakes as well as body mass index were taking into account; such that individuals in the top tertile of rice consumption had 2.46 times greater odds of glioma compared with those in the bottom tertile (OR: 2.46, 95% CI 1.01–5.97). We found that rice consumption was positively associated with risk of glioma in adults. Further prospective studies are required to confirm this finding.

Sun exposure and multiple sclerosis risk in Norway and Italy: The EnvIMS study

2014 ◽  
Vol 20 (8) ◽  
pp. 1042-1049 ◽  
Author(s):  
Kjetil Bjørnevik ◽  
Trond Riise ◽  
Ilaria Casetta ◽  
Jelena Drulovic ◽  
Enrico Granieri ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Case Control Study ◽  
Sun Exposure ◽  
Case Control ◽  
Childhood And Adolescence ◽  
Outdoor Activity ◽  
Red Hair ◽  
Multiple Sclerosis Risk ◽  
Sunscreen Use ◽  
Control Study

Objectives: The objective of this paper is to estimate the association between multiple sclerosis (MS) and measures of sun exposure in specific age periods in Norway and Italy. Methods: A total of 1660 MS patients and 3050 controls from Italy and Norway who participated in a multinational case-control study (EnvIMS) reported sun habits during childhood and adolescence. Results: A significant association between infrequent summer outdoor activity and increased MS risk was found in Norway and in Italy. The association was strongest between the ages of 16 and 18 years in Norway (odds ratio (OR) 1.83, 95% confidence interval (CI) 1.30–2.59), and between birth and age 5 years in Italy (OR 1.56, 95% CI 1.16–2.10). In Italy a significant association was also found during winter (OR 1.42, 95% CI 1.03–1.97). Frequent sunscreen use between birth and the age of 6 years was associated with MS in Norway (OR 1.44, 95% CI 1.08–1.93) after adjusting for outdoor activity during the same period. Red hair (OR 1.67, 95% CI 1.06–2.63) and blonde hair (OR 1.36, 95% CI 1.09–1.70) were associated with MS after adjusting for outdoor activity and sunscreen use. Conclusion: Converging evidence from different measures underlines the beneficial effect of sun exposure on MS risk.

scholarly journals Association of Empirically Derived Food-based Inflammatory Potential of the Diet and Breast Cancer: A Hospital Based Case-control Study

2021 ◽  
Author(s):  
Mahtab Ghanbari ◽  
Hossein Imani ◽  
Hossein Shahinfar ◽  
Sakineh Shab-Bidar
Keyword(s):  
Breast Cancer ◽  
Case Control Study ◽  
Case Control ◽  
Dietary Intakes ◽  
Food Groups ◽  
Anthropometric Measures ◽  
Inflammatory Index ◽  
Modifiable Factor ◽  
Logistic Regressions ◽  
Control Study

Abstract Background: Diet may be a modifiable factor in the prevention of breast cancer (BC) by modulating inflammation. We used a food-based empirical dietary inflammatory index (FDII) to evaluate the association between FDII and odds of breast cancer in Iranian women.Methods: The present case-control study carried out on 150 age-matched women with newly diagnosed breast cancer and controls. Data for dietary intake and anthropometric measures were collected. FDII score was developed according to participants dietary intakes of 21 pre-defined food groups. Multivariate odds ratios (OR) with 95% confidence intervals (CI) were used to investigate the association of empirically derived food-based inflammatory potential of the diet and breast cancer. Results: Our finding indicated that participants in the top tertile of FDII score had a higher odds of breast cancer (OR: 1.73; 95% CI: 1.14 - 2.53, P=0.01) compared with those in the first tertile. . After controlling confounders, multivariate logistic regressions showed in those at the third tertile of FDII chance of breast cancer was 1.7 times higher than those in the first terile (OR: 1.72; 95% CI: 1.12- 2.58, P=0.01). Conclusions: The results of our study suggested that more pro-inflammatory diets (higher FDII scores) are associated with increased breast cancer risk. These findings suggest that developing an effective dietary modification based on FDII may reduce risk of breast cancer.

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