scholarly journals The Effect of Oxymel Syrup on Some Cardiovascular Risk Factors in Overweight and Obese People: A Randomized Controlled Trial Study

2021 ◽  
Author(s):  
Marjan Mahdavi Roshan ◽  
Arsalan Salari ◽  
Sogol Emaminejad ◽  
Shirin Parvinroo ◽  
Asieh Ashouri ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Controlled Trial ◽  
Test Group ◽  
The Body ◽  
Risk Indicators ◽  
Blood Cholesterol ◽  
Control Group ◽  
Obese People

High blood pressure, diabetes, hyperlipidemia and obesity are risk factors for cardiovascular diseases. With regard to the significant role of a healthy diet in the prevention and even treatment of diseases together with the high cost and side effects of drugs, finding foods effective in the treatment of metabolic disorders has been widely considered. This study aimed to evaluate the effect of oxymel – an Iranian traditional syrup with vinegar base – on cardiovascular risk indicators in obese and overweight people. Candidates were selected based on a set of inclusion criteria and were divided into two groups of control and test. The control group received 250 cc of water, while the test group received 250 cc water containing 30 cc of the oxymel for 30 days. Anthropometric and biochemical indicators were measured at the beginning and end of the study. The results showed that there were no significant changes in the body mass index, waist circumference, hip circumference, waist to hip ratio, HDL, LDL, Triglycerides, systolic and diastolic blood pressure, and blood glucose level. However, weight (P = 0.053) and cholesterol (P = 0.083) decreased relatively significantly in the test group compared to the control group. This study shows that consumption of oxymel has positive cardiovascular effects such as lowering the blood cholesterol level and can contribute to weight loss; however, studies with a larger sample size are recommended.

CARDIOVASCULAR RISKS IN OBSTRUCTIVE SLEEP APNEA SYNDROME WITH IMPROVED SASD07 COMPARE TO STARDUST II

2014 ◽  
pp. 77-86
Author(s):  
Anh Tien Hoang ◽  
Thi Y Nhi Nguyen ◽  
Luu Trinh Nguyen ◽  
Thi Hong Diep Phan ◽  
Huu Cat Nguyen ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Sleep Apnea ◽  
Sleep Apnea Syndrome ◽  
Hdl Cholesterol ◽  
Control Group ◽  
Positive Correlation ◽  
Obstructive Sleep ◽  
Apnea Syndrome

Background : Sleep Apnea Syndrome (SAS) is a cause of hypertension, increasingcardiovascular risk and cardiovascular disease such as stroke, coronary artery disease, myocardial infarction, arrhythmias, heart failure, increasing the risk of death in patients with heart disease, independent of other causative factors. So far, in Vietnam there are very few studies on Obstructive Sleep Apnea Syndrome (OSAS) and cardiovascular risk factors . Self-making SASD07 is trustly for detecting OSAS with statistical significiant in comparision with StarDustII (gold criteria). Subjects and Methods: Cross sectional study, comparision with control group: 136 peoples (68 in disease group and 68 in control group). Patients were parallelly measured with StarDustII and SASD07 to detect OSAS and find the corellation with cardiovascular risk factors. Results: There is a positive correlation between SBP with the severity of OSAS (r = 0.459, p < 0.001), positive correlation between DBP with the severity of OSAS (r = 0.352, p < 0.003). No statistically significant differences between severe OSAS and fasting blood glucose, cholesterol, HDL Cholesterol, Non - HDL Cholesterol, LDL Cholesterol and TG median (p > 0.05). There is a positive correlation between AHI and neck circumference (r = 0.511, p < 0.001), waist circumference (r = 0.585, p < 0.001), BMI (r = 0.380, p < 0.01). SASD07 diagnostic value of detecting OSAS compared with StarDustII have Kappa = 0.72, (standard error 0.06, p <0.001). Conclusion: The risk factors related to OSAS in our study is neck circumference, waist circumference, systolic blood pressure, diastolic blood pressure. SASD07 have a good value in diagnosing of OSAS compared with polysomnography StarDustII. Key words: Sleep Apnea Syndrome, cardiovascular risk factor, SASD07.

Effect of Dietary Education on Cardiovascular risk Factors in Rheumatoid Arthritis Patients

2020 ◽  
Vol 16 ◽  
Author(s):  
Rahil Taheri ◽  
Shahram Molavynejad ◽  
Parvin Abedi ◽  
Elham Rajaei ◽  
Mohammad Hosein Haghighizadeh
Keyword(s):  
Rheumatoid Arthritis ◽  
Risk Factors ◽  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Statistical Tests ◽  
Intervention Group ◽  
Serum Levels ◽  
Control Group ◽  
Dietary Education

Aim: The aim of this study was to investigate the effect of dietary education on cardiovascular risk factors in patients with rheumatoid arthritis. Method: In this randomized clinical trial, 112 patients with rheumatoid arthritis were randomly assigned into two groups, intervention and control. Dietary education was provided for the intervention group in 4 sessions; anthropometric measurements, serum levels of RF, triglycerides, cholesterol, HDL, LDL, and fasting blood sugar were measured before and three months after intervention. Data was analyzed using SPSS software and appropriate statistical tests. Results: The mean of total cholesterol (p <0.001), triglycerides (p = 0.004), LDL (p <0.001), systolic blood pressure (p = 0.001), diastolic blood pressure (p = 0.003), FBS and BMI (p <0.001) were decreased significantly in the intervention group after education compared the control group. Conclusion: Traditional care for rheumatoid arthritis patients is not enough. Patients need more education in order to improve their situation.

scholarly journals The Effects of Moderate and High-Intensity Interval Training in Cardiac Rehabilitation of Bodybuilders with Arterial Hypertension: a Randomized Controlled Trial

2020 ◽  
Vol 100 (6) ◽  
pp. 108-113
Author(s):  
A.B. Miroshnikov ◽  
A.D. Formenov ◽  
A.B. Smolensky
Keyword(s):  
Blood Pressure ◽  
Arterial Hypertension ◽  
High Intensity ◽  
Controlled Trial ◽  
Sport Activity ◽  
Interval Training ◽  
Training Group ◽  
The Body ◽  
Control Group ◽  
High Intensity Interval

Athletes of power sports, often appear to us as a model of a beautiful and healthy body, but the health of the cardiovascular system ofthese athletes has long falls under the gaze of cardiologists and sport physicians. Purpose of the study. A comparative analysis of the influence of a uniform and high-intensity aerobic exercise on blood pressure lowering power sports athletes with hypertension. Research Methods. The study involved 83 representatives of power sports (bodybuilding) with arterial hypertension. The average age of male athletes was 31.2 ± 4.5 years, and the body mass index was 32.4 ± 2.8 kg/m 2. To achieve this goal, the following methods were used: examination, interrogation, triple measurement of blood pressure, ergospirometry and methods of mathematical statistics. Athletes were randomized into three groups: interval training group (n = 33), uniform training (n = 30) and control group (n = 20). For 120 days (3 times a week), the athletes of the main groups performed various aerobic work programs, and the control group athletes trained according to their traditional strength protocol. Results. After 120 days of physical rehabilitation, a similar, significant decrease in systolic and diastolic blood pressure occurred in themain intervention groups. A decrease in blood pressure in the control group was not statistically significant. Conclusions. Despite the similar benefits in cardio-rehabilitation interval work required 38% less time, which can significantly affect adherence to a non-specific for this sport activity and screening of participant’s lengthy rehabilitation.

scholarly journals Population Based Survey Study Associated With Prevalence Of Cardiovascular Risk Factors In India

2020 ◽  
Vol 3 (1) ◽  
pp. 144-148
Author(s):  
Mandheer Kaur ◽  
Sahil Sharma ◽  
Chaitanayajit Singh ◽  
Ankit Magotra ◽  
Preeti Devi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Age Groups ◽  
Heart Rhythm ◽  
Population Based ◽  
Blood Cholesterol ◽  
Survey Study ◽  
Level Of Knowledge ◽  
Group 3

The present study was conducted on 204 individuals of different regions of Chandigarh, Mohali, Panchkula, Himachal Pradesh and Haryana, India, to assess the level of knowledge and awareness of risk factors associated with cardiovascular disease (CVD) in targeted population. Population survey based study was carried out in people grouped in three age groups (Group 1: <18 years, Group 2: Between 18-40 years, Group 3: Above 40). Cardiovascular risk assessment questionnaire was used to assess the level of knowledge and awareness of risk factors via goggle forms and manually filling the same forms. Among risk factors 8.8 percent persons from our targeted population encountered with heart attack, angina, abnormal Heart Rhythm with significant hike in CVD cases was observed in group 3 individuals. Incidence of high blood pressure was observed in 32.4%, 4.9% are normal and 62.7% are unaware of their blood pressure status. Similarly, majority of the population 42.6% are not aware of their blood cholesterol level. The participants were not aware about regular physical activity and exercise, food intake to lower risk factors for the heart disease. There is an urgent need to increase awareness among the population utilizing community based education programs.

1107Reduction of cardiovascular disease risk factors in rural, medically under-served, socioeconomically distressed, high-risk individuals: a randomized controlled trial

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
D Moser ◽  
M L Chung ◽  
F Feltner ◽  
T A Lennie ◽  
M J Biddle
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Risk Reduction ◽  
Controlled Trial ◽  
Self Care ◽  
Density Lipoprotein ◽  
Control Group ◽  
Cvd Risk Factors ◽  
Cvd Risk ◽  
Randomized Controlled

Abstract Background People in rural, socioeconomically distressed areas of the world suffer from marked cardiovascular disease (CVD) disparities. Despite the CVD disparities seen in rural, distressed areas, efforts directed toward CVD risk reduction and prevention are limited. We conducted a randomized, controlled trial to determine the effect of an individualized, culturally appropriate, self-care CVD risk reduction intervention (HeartHealth) compared to referral of patients to a primary care provider for usual care on the following CVD risk factors: tobacco use, blood pressure, lipid profile, body mass index, depressive symptoms, and physical activity levels. Methods The study protocol and intervention were developed with a community advisory board of lay community members, business owners, local government officials, church leaders, and healthcare providers. We enrolled 355 individuals living in Appalachia with two or more CVD risk factors. The intervention was delivered in person to groups of 10 or fewer individuals over 12 weeks. In the first session, participants chose their CVD risk reduction goals. HeartHealth was designed to provide participants with self-care skills targeting CVD risk reduction while reducing barriers to risk reduction found in austere rural environments. The targeted CVD risk factors were measured at baseline and 4 and 12 months post-intervention. Repeated measures data were analyzed with mixed models. Results More individuals in the intervention group compared to the control group met their lifestyle change goal (50% vs 16%, p<0.001). The intervention produced a positive impact on systolic blood pressure (p=0.002, time X group effect), diastolic blood pressure (p=0.001, time x group), total cholesterol (p=0.026, time x group), high density lipoprotein (p=0.002, time x group), body mass index (p=0.017, time x group), smoking status (p=0.01), depressive symptoms (p=0.01, time x group), and steps per day (p=0.001, time x group). Compared to the control group, improvement was seen at 4 months in these risk factors and the positive changes were maintained through 12 months. There were no differences seen across time by group in low density lipoprotein or triglyceride levels. Conclusion Interventions like HeartHealth that focus on self-care and that are derived in collaboration with the community of interest are effective in medically underserved, socioeconomically distressed rural areas. Acknowledgement/Funding Patient Centered Outcomes Research Institute

scholarly journals Association of theHindIIIand S447X Polymorphisms inLPLGene with Hypertension and Type 2 Diabetes in Mexican Families

2012 ◽  
Vol 33 (6) ◽  
pp. 313-320 ◽  
Author(s):  
Salvador Muñoz-Barrios ◽  
Iris Paola Guzmán-Guzmán ◽  
José Francisco Muñoz-Valle ◽  
Aralia Berenice Salgado-Bernabé ◽  
Lorenzo Salgado-Goytia ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Type 2 Diabetes ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Diastolic Blood Pressure ◽  
Gene Polymorphisms ◽  
The Body ◽  
Mexican Families

Lipoprotein lipase (LPL) is a key enzyme in lipid metabolismand is associatedwith obesity, dyslipidemias, hypertension (HTN) and type 2 diabetes mellitus (T2DM).LPLgene polymorphisms can be related with the development of cardiovascular risk factors. The present study was conducted to analyze the relationship of theHindIIIand S447X polymorphisms inLPLgene with cardiovascular risk factors in Mexican families. The study population comprised ninety members of 30 Mexican families, in which an index case had obesity, were included in the study. We evaluated the body composition by bioelectrical impedance. Peripheral blood samples were collected to determine biochemical parameters. Screening for both polymorphisms was made by PCR-RFLPs. In the parents, both polymorphisms were in Hardy-Weinberg’s equilibrium. We found that the genotype T/T ofHindIIIwas associated with diastolic blood pressure ≧ 85 mmHg (OR = 1.1;p= 0.011), whereas the genotype C/C of S447X was associated with systolic blood pressure ≧ 130 mmHg (OR = 1.2;p< 0.001), diastolic blood pressure ≧ 85 mmHg (OR = 1.3;p< 0.001), T2DM (OR = 1.3;p< 0.001) and with increase of total cholesterol (β = 23.6 mg/mL;p= 0.03). These data suggest that theHindIIIand S447XLPLgene polymorphisms can confer susceptibility for the development of hypertension and T2DM in Mexican families.

P1255DIASTOLIC BLOOD PRESSURE IS ASSOCIATED WITH BRAIN ATROPHY IN HEMODIALYSIS PATIENTS: A SINGLE CENTER CASE CONTROL STUDY

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Keren Cohen-Hagai ◽  
Feda Fanadka ◽  
Tania Grumberg ◽  
Guy Topaz ◽  
Naomi Nacasch ◽  
...  
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Brain Atrophy ◽  
Hemodialysis Patients ◽  
Cerebral Hypoperfusion ◽  
Common Finding ◽  
Control Group ◽  
Chronic Hypertension

Abstract Background and Aims Brain atrophy (BA) is a common finding in neuroimaging of hemodialysis (HD) patients, representing a parenchymal cerebral damage. Likely contributing factors to BA are age, chronic hypertension, diabetes mellitus and other cardiovascular risk factors of atherosclerosis that are also common among HD patients. BA may also occur due to focal ischemia and hypoperfusion during HD. However, data on optimal blood pressure (BP) in these patients are limited. The goal of this study was to determine whether the prevalence and severity of BA would be higher among HD patients with lower BP. Method A blinded neuroradiologist graded BA of all HD patients who underwent brain non-contrast computerized tomography (CT) from 2015 to 2017 in our institution. Age-and sex-matched patients with normal kidney function who underwent brain CT during the same period and technique served as the control group Results A total of 280 patients were included in this retrospective study, with average BP of 140/70 mmHg among HD patients and 142/75 mmHg in the control group. BA was more common in dialysis patients and its severity increased with age and traditional cardiovascular risk factors. We observed a significant negative correlation between diastolic BP (DBP) at dialysis initiation and BA. Average DBP decreased with increasing severity of BA. These findings were observed in both HD and non-CKD patients. Conclusion Brain atrophy was associated with lower DBP, which may induce cerebral hypoperfusion and ischemia. This finding should discourage over-treatment of hypertension in hemodialysis patients.

scholarly journals The Effect of Gum Arabic (Acacia Senegal) on Cardiovascular Risk Factors and Gastrointestinal Symptoms in Adults at Risk of Metabolic Syndrome: A Randomized Clinical Trial

Nutrients ◽  
2021 ◽  
Vol 13 (1) ◽  
pp. 194
Author(s):  
Amjad H. Jarrar ◽  
Lily Stojanovska ◽  
Vasso Apostolopoulos ◽  
Jack Feehan ◽  
Mo’ath F. Bataineh ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
At Risk ◽  
Cardiovascular Risk ◽  
Cardiovascular Risk Factors ◽  
Controlled Trial ◽  
Gastrointestinal Symptoms ◽  
Gum Arabic ◽  
Treatment Compliance ◽  
Risk Indicators

Gum Arabic (GA) is a widely-used additive in food processing, but is also historically used in a number of traditional therapies. It has been shown to have a broad range of health benefits, particularly in improving important cardiovascular risk indicators. Metabolic syndrome and its associated cardiac outcomes are a significant burden on modern healthcare systems, and complementary interventions to aid in its management are required. We aimed to examine the effect of GA on those with, or at risk of, metabolic syndrome to identify an effect on improving important disease parameters related to cardiovascular outcomes. A single-blind, randomized, placebo-controlled trial was conducted to identify the effects of daily GA supplementation on metabolic and cardiovascular risk factors. A total of 80 participants were randomized to receive 20 g of GA daily (n = 40) or placebo (1 g pectin, n = 40) for 12 weeks. Key endpoints included body-anthropometric indices, diet and physical activity assessment, and blood chemistry (HbA1c, fasting glucose, and blood lipids). Of the 80 enrolled, 61 completed the study (intervention: 31, control: 30) with 19 dropping out due to poor treatment compliance. After 12 weeks, the participants receiving the GA showed significant decreases in systolic and diastolic blood pressure, fat-free body mass, energy and carbohydrate consumption, and fasting plasma glucose, as well as increased intake of dietary fiber. They also reported improvements in self-perceived bloating and quality of bowel movements, as well as a decreased appetite score following GA consumption. These results suggest that GA could be a safe and beneficial adjunct to other treatments for those with, or at risk of, metabolic syndrome.

Abstract P333: Carotid Intima Media Echolucency is Related to Age, Female Sex, Systolic Blood Pressure, BMI and Smoking in Patients with Familial Hypercholesterolemia

Circulation ◽  
2014 ◽  
Vol 129 (suppl_1) ◽  
Author(s):  
Karlijn A Groenewegen ◽  
Sanne A Peters ◽  
Hester M den Ruijter ◽  
Michiel L Bots
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Systolic Blood Pressure ◽  
Cardiovascular Risk Factors ◽  
Familial Hypercholesterolemia ◽  
Controlled Trial ◽  
Multivariable Model ◽  
Female Sex ◽  
The Common

Background: Atherosclerotic vascular disease can be assessed non-invasively with B-mode ultrasound. Echolucency is an ultrasound characteristic which is measured as the Gray Scale Median (GSM). Echolucent structures appear dark on ultrasound images; echogenic structures appear light. Echolucency of the carotid intima-media is thought to be a marker of the content of the vascular wall, where low values of GSM might reflect inflammation and/or high lipid content and high values of GSM reflect increased collagen and/or calcifications. In previous studies in asymptomatic individuals, echolucency of the carotid intima-media was associated with cardiovascular risk factors. Studies in high-risk populations are lacking. Aim: To assess the relation between cardiovascular risk factors and carotid intima media echolucency in patients with familial hypercholesterolemia. Methods: Baseline data were used from the RADIANCE 1 trial, a randomized controlled trial on the effects of atorvastatin and torcetrapib (a CETP-inhibitor) compared to atorvastatin alone in familial hypercholesterolemia. Echolucency of the common carotid artery intima media was measured as the mean GSM of the first baseline visit. Linear mixed effects models were used to assess the relation between each cardiovascular risk factor and mean GSM (adjusted for age, sex and carotid intima media thickness (CIMT), and in a multivariable model containing all risk factors). We studied systolic blood pressure (SBP), body mass index (BMI), high and low density lipoprotein (HDL and LDL), triglycerides (TGs), smoking, diabetes mellitus and C - reactive protein (CRP). Results: 875 patients were included in the current analysis. Mean age was 46 years (sd 13) and 50% was female. Mean GSM was 67 (sd 18). In age, sex and CIMT adjusted analyses, higher age (ß/sd: -5.71 (95% CI-6.82;-4.61)), female sex (β:-3.53 (95% CI -5.32;-1.73)), higher SBP (β/sd:-1.86 (95% CI -2.81;-0.91)), higher BMI (β/sd:-2.37 (95% CI -2.26;-1.29)) and higher levels of TGs (β/sd:-1.34 (95% CI -2.21;-0.47 were related to a lower GSM (i.e, more echolucency) and smoking (ß 2.91 (95% CI 0.52-5.29)) was related to a higher GSM. In the multivariable model, age (β/sd: -4.92 (95% CI -6.18;-3.65)), female sex (β: -4.35 (-6.41;-2.29), systolic blood pressure (β/sd: -1.32 (-2.38;-0.25) and BMI (β/sd: -1.82 (-2.90;-0.73)) were related to a lower GSM and smoking (β: 2.78 (0.39;5.18)) was related to a higher GSM. Conclusion: Several established risk factors were related to the echolucency of the common carotid intima media in patients with familial hypercholesterolemia.

Abstract WP416: Tai Chi Exercise Reduces Stroke Risk Factors: A Randomized Controlled Trial

Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Aileen W Chan ◽  
Doris Y Leung ◽  
Janet W Sit ◽  
S.Y. Chair
Keyword(s):  
Risk Factors ◽  
Blood Pressure ◽  
Tai Chi ◽  
Stroke Risk ◽  
Controlled Trial ◽  
Control Group ◽  
Brisk Walking ◽  
Stroke Risk Factors ◽  
Tai Chi Exercise ◽  
Walking Group

Background and Purpose: Risk factors for stroke include hypertension, diabetes, low blood high-density lipoprotein (HDL), physical inactivity and obesity. Among these, hypertension is the most important controllable risk factor for stroke. A total of at least 30 minutes exercise every day is recommended for prevention of stroke. This study aims to evaluate the effectiveness of Tai Chi exercise versus brisk walking exercise in reducing stroke risk factors. Methods: This was a randomized controlled trial. A total of 246 subjects with stroke risk factors were recruited from two outpatient clinics. They were randomly assigned into one of the three groups, namely, Tai Chi group (n=82), walking group (n=82), and control group (n=82). The Tai Chi group received Tai Chi training, which consisted of two 60-minute sessions each week for three months, and self-practice for 30 minutes every day. The walking group performed brisk walking for 30 minutes every day. The control group was advised to maintain their routine activities. The primary outcome was blood pressure. Secondary outcomes included fasting blood for lipid profile and sugar; body mass index, waist circumference and body fat percentage. Data were collected at baseline and 3-month post-intervention. Generalized estimating equations (GEE) model was used to compare the changes in outcomes across time between groups. Results: The mean age of the 246 subjects was 64.4 (SD=9.8), with 45.5% (n=112) were male. The GEE analysis showed that, as compared to the control group, the Tai Chi group demonstrated statistically significant greater reduction in systolic blood pressure (B=-10.25, P=0.001) and diastolic blood pressure (B=-6.50, P=0.002), and significant increase in HDL (B=0.16, P=0.012), while no significant differences were noted in the walking group. No significant changes were noted in the other outcome variables at 3-month. Conclusion: Regular Tai Chi exercise was effective in reducing the stroke risk factors by reducing high blood pressure and increasing HDL. Longer follow-up period was suggested for monitoring the sustainability of both Tai Chi and brisk walking to reveal the empirical effects of both exercises on stroke prevention.

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