scholarly journals Contamination of food with cadmium and dioxins – influence on the human body

2019 ◽  
Vol 65 (3) ◽  
Author(s):  
Aleksandra Słojewska ◽  
Izabela Gutowska
Keyword(s):  
General Population ◽  
Health Effects ◽  
Human Body ◽  
Bone Mineralization ◽  
The Body ◽  
Food Sources ◽  
Hormonal Balance ◽  
Small Doses ◽  
Contaminated Food

Introduction: Food is a carrier of many pollutants nowadays. For cadmium and dioxins, it is the main source of these compounds in the general population. Hence, the aim of this work was to collect data on the health effects associated with exposure to cadmium and dioxins which get into the human body through food.Materials and methods: A literature review was conducted by searching the scientific Medline database (PubMed) and Google Scholar.Results: Health effects associated with a long-term exposure to low doses of cadmium and dioxins may be nonspecific and are rarely attributed to food sources. These may cause disorders affecting hormonal balance, kidney function, lipid metabolism, fertility, cognitive function, bone mineralization, and susceptibility to diseases and allergies. These compounds may also lead to cancer development.Conclusions: The general population faces the problem of longterm exposure to small doses of these substances due to their accumulation in the body, even if their amounts do not exceed the relevant standards. The health effects of this type of exposure may be significantly delayed and are not likely to be attributed to the consumption of contaminated food. Consumers wishing to reduce the amounts of these compounds delivered to the body should limit the consumption of grilled and smoked products, and should also opt for organic food.

Rational vitamin therapy

1982 ◽  
Vol 63 (1) ◽  
pp. 58-61
Author(s):  
I. M. Raskin ◽  
J. S. Zimmerman
Keyword(s):  
Adverse Effect ◽  
High Activity ◽  
Human Body ◽  
Complex Interaction ◽  
The Body ◽  
Scientific Development ◽  
Functional Connections ◽  
Vitamin Therapy ◽  
Excessive Intake

Free sale of vitamin preparations with high activity, insufficient scientific development of the consequences of excessive intake of vitamins, the spread of superficial knowledge about vitamins among the population have led to numerous facts of the adverse effect of certain vitamins on the human body. It turned out that unjustifiably long-term intake of large doses of one of the vitamins can cause a deficiency in the body of another vitamin, cause the development of hypovitaminosis. The complex interaction of vitamins in the human body is due to the presence, they have metabolic and functional connections.

The Research Progress of Heavy Metals in PM2.5

2014 ◽  
Vol 955-959 ◽  
pp. 1397-1404 ◽  
Author(s):  
Li Na Shi ◽  
Xun Xu ◽  
Xiao Yan Dou ◽  
Xu Dong Zhao
Keyword(s):  
Heavy Metals ◽  
Air Pollution ◽  
Human Health ◽  
Human Body ◽  
Chemical Form ◽  
The Body ◽  
Detection Methods ◽  
Research Progress ◽  
Depth Study

PM2.5 is one of the most important components in air pollution. It is also the focus of the most closely watched at home and abroad. Based on its small size, complex components, and strongenvironmental activity, it can be used as a carrier for chemicals, heavy metals, bacteria, toxins and carcinogens into the body. Then, as a result, it will affect Human Body Health. Heavy metals are important components of PM2.5, and the long-term accumulation of heavy metals in PM2.5 poses a great threat on human health and the environment. This paper reviewed the sources, distribution methods,chemical form, detection methods, disposal way, research progress of heavy metals in PM2.5. As a result, it provided a reference for in-depth study on the future.

scholarly journals Parycalcitol + J131 - A New Route to Treatment Secondary Hyperparathyroidism in Patients with Chronic Kidney Disease on Long-term Dialysis?

2019 ◽  
Vol 3 (3) ◽  
pp. 1-4
Author(s):  
Radosław Drozd ◽  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Secondary Hyperparathyroidism ◽  
Bone Metabolism ◽  
Soft Tissues ◽  
Bone Mineralization ◽  
The Body ◽  
Calcium Deposition ◽  
Phosphate Binding

Two cases with the dramatic course of secondary hyperparathyroidism in patients with chronic kidney disease on long-term dialysis. Has anything possible been done in management of these patients? Complications associated with impaired bone mineralization among patients with chronic kidney disease on long-term dialysis are observed frequently with an array of pathologic processes being found. Kidney osteodystrophy may be associated with either increased or decreased (adynamic bone disease, osteomalacia, aluminum-induced osteopenia) bone metabolism, as well as mixed forms related to the B2 microglobulin amyloidosis. Differential diagnosis of various types of osteopathy is difficult and is usually based on the histologic assessment of the bone biopsy. The most typical bone complication in patients with impaired kidney function is osetodistophy with increased bone metabolism, caused by secondary hyperparathyroidism clinically manifesting as osteitis fibrosa. High serum levels of PTH induce osteoclast and osteoblast activity. Early changes, with characteristic increase in the woven osteoid suggesting early, increased osteoplastic bone resorption may be found in a significant percentage of patients with GFR>60ml/min/1,73m2 of the body surface. Lower values of the GFR are associated with both faster bone synthesis and more active resorption with progressive increase in the intraosseous fibrosis and decreased bone mineralization. As the abnormalities progress, which is especially marked in patients on long-term dialysis, a rage of clinical symptoms, such as: severe bone and joint pain, bone deformation, pathological fractures, especially in the spinal region, calcifications of the soft tissues and vessels, including heart valves and lungs. In children, the most common abnormality is growth impairment. In some patient’s skin calcifications, with subsequent necrosis, due to increased calcium deposition in small and medium arteries. The diagnosis is based on the typical clinical picture, biochemical parameters (calcium and phosphate ratio, parathormone levels, characteristic radiologic charges and sometimes, bone histology. Prevention and treatment of these complications includes effective dialysis, appropriate low-phosphate diet with limitation of the protein supply to the 0.8g/kg of the body mass, adequate calcium and active Vitamin D3 supply, introduction of the phosphate binding medications (sevelamer or lantan) as well as calcimimetic use (substances activating parathyroid gland calcium receptors inhibiting both its up-regulation and PTH secretion). In the severe cases, with insufficient effect of the treatment described above, parathyroidectomy is required after close ultrasound and scintigraphy-based assessment of these glands. However, even such treatment may be insufficient in some cases, as presented below.

Keep Cell Phones and PDAs Away From EMG Sensors and the Human Body to Prevent Electromagnetic Interference Artifacts and Cancer

Biofeedback ◽  
2009 ◽  
Vol 37 (3) ◽  
pp. 114-116 ◽  
Author(s):  
I-Mei Lin ◽  
Erik Peper
Keyword(s):  
Human Body ◽  
Electromagnetic Interference ◽  
Cell Phone ◽  
Cell Phones ◽  
Epidemiological Studies ◽  
The Body ◽  
Physiological Signals ◽  
Cell Phone Use ◽  
Physiological Signal

Abstract Cell phones produce electromagnetic interference (EMI), which can cause artifacts in physiological recordings and be misinterpreted by the clinician. This study investigated the possible effect of EMI (electrical artifact) on physiological recordings when cell phones are activated/ringing. The procedure consisted of placing the cell phone at varying distances from surface electromyographic sensors. Depending on the orientation of the cell phone's antenna, the EMI produced an artifact in the physiological signal for up to 175 cm (6 ft) that can be misinterpreted by the therapist. To avoid EMI artifacts, clients and therapists should turn off their cell phones when recording physiological signals. This means turning the cell phone off and not just switching it to vibrate. In addition, recent epidemiological studies suggest that long-term intensive cell phone use may increase the risk of gliomas, auditory tumors, and salivary tumors on the side of the head to which the person places the cell phone. Thus, to reduce artifacts and biological harm, the authors recommend keeping the cell phone away from the body and the biofeedback equipment.

Test of a Model for Predicting the Body Burden of Trace Contaminants in Aquatic Consumers

1976 ◽  
Vol 33 (5) ◽  
pp. 1162-1166 ◽  
Author(s):  
Jerry W. Elwood ◽  
L. Dean Eyman
Keyword(s):  
Lepomis Macrochirus ◽  
Body Burden ◽  
The Body ◽  
Model Parameters ◽  
Feeding Experiment ◽  
Trace Contaminants ◽  
Short Term Exposure ◽  
Contaminated Food ◽  
Exposure Conditions

A model for predicting the accumulation and retention of trace contaminants obtained through food ingestion in aquatic consumers was tested for short-term exposure conditions. Model parameters were determined in a single-feeding experiment using bluegill (Lepomis macrochirus) and food labeled with 137Cs. Independent of this single-feeding experiment, bluegill were allowed to ingest 137Cs contaminated food over a 16-day period and the predicted and measured body burden of the radionuclide were compared. The model realistically simulated the absorption of 137Cs from the gastrointestinal tract and its accumulation over the 16-day period. Average body burden of 137Cs in bluegill was within 25% of the predicted body burden when the experiment was terminated. Apparent equilibrium of 137Cs in bluegill by day 16 suggests that this two-compartment linear model does not apply to the long-term accumulation of cesium in fish. The model appears most applicable for predicting body burdens of trace contaminants under acute exposure conditions that simulate an accidental release.

scholarly journals Carbon/carbon implants in oral and maxillofacial surgery – Part 2

2012 ◽  
Vol 153 (19) ◽  
pp. 744-750 ◽  
Author(s):  
Béla Sebők ◽  
Gábor Kiss ◽  
Péter János Szabó ◽  
Dániel Rigler ◽  
László Milán Molnár ◽  
...  
Keyword(s):  
Human Body ◽  
State Of The Art ◽  
Maxillofacial Surgery ◽  
Thick Layer ◽  
The Body ◽  
Oral And Maxillofacial Surgery ◽  
Carbon Fibres ◽  
Aesthetic Results ◽  
Main Components

In their previous report, the authors presented observations regarding the long-term application of carbon/carbon implants. After evaluating the good functional and aesthetic results, the effect of the human body on the structure and morphology of the implants was investigated with state of the art methods. An implant retrieved from the body after eight years was compared to implants which were sterilized but not implanted (reference). Carbon and oxygen were the main components of both implants, however, as a result of the interaction with the human body the amount of oxygen increased 3–4 times and phosphorus, sulphur, calcium and iron were detectable as trace elements on the surface. The width of the carbon fibres (5–7 µm) building up the implants was not changed during the interaction with the human body. The surface of the implant retrieved from the human body was covered with a 15–17 µm thick layer, not present on the reference implant, having a similar composition to that of the carbon fibres (high amount of calcium that is typical to bone tissue was not detected). According to these results, the structure and the morphology of the implants were not altered notably by the human body. Orv. Hetil., 2012, 153, 744–750.

Long-Term Health Effects of PCBs and Related Compounds: A Comparative Analysis of Patients Suffering from Yusho and the General Population

2017 ◽  
Vol 74 (2) ◽  
pp. 203-217 ◽  
Author(s):  
Manabu Akahane ◽  
Shinya Matsumoto ◽  
Yoshiyuki Kanagawa ◽  
Chikage Mitoma ◽  
Hiroshi Uchi ◽  
...  
Keyword(s):  
Comparative Analysis ◽  
General Population ◽  
Health Effects ◽  
Related Compounds

Biomechanical Modeling of Human Finger

2013 ◽  
Vol 430 ◽  
pp. 217-221
Author(s):  
Panaitescu Liess Radu
Keyword(s):  
Human Body ◽  
Degrees Of Freedom ◽  
Soft Tissues ◽  
Mechanical Vibration ◽  
The Body ◽  
Internal Organs ◽  
Vibration White Finger ◽  
Human Finger ◽  
Stiffness And Damping

Many of the studies in the biomechanics of the human body made globally focused primarily on hand-arm. This segment of the human body is considered a "gateway" of vibrations to other parts of the body or to internal organs. A long-term exposure to these mechanical vibration (caused by vibrating hand equipment: drill, grinder, etc.) affects the soft tissues and may lead to a dangerous syndrome, that is particularly vibration white finger (VWF), which is narrowing of blood vessels, a phenomenon that in time and untreated can even cause gangrene. This article focuses on a dynamic model with three degrees of freedom of the human finger. Some dynamic characteristics, such as centre of gravity, stiffness and damping, using both a rigid body structure system and computer simulations can be determined after measuring the vibrations.

scholarly journals Metal distribution patterns in tissues from implanted Sprague-Dawley rats

2021 ◽  
Vol 5 ◽  
pp. 239784732110628
Author(s):  
Vernieda B Vergara ◽  
Jessica F Hoffman ◽  
John F Kalinich
Keyword(s):  
Health Effects ◽  
Inductively Coupled Plasma ◽  
Treatment Strategies ◽  
Distribution Patterns ◽  
Depleted Uranium ◽  
The Body ◽  
Sprague Dawley ◽  
Sprague Dawley Rats ◽  
Long Term Treatment

Background: Injuries with fragments of embedded metal are a common occurrence in armed conflicts. Unfortunately, the list of metals encountered on the modern battlefield are practically endless while the short- and long-term health effects, especially when embedded as in a shrapnel wound, are not well understood. One of the major concerns with these types of injuries is the solubilization of the embedded metal and the translocation and deposition to various organs of the body. Methods: Using a rodent model system developed in our laboratory to assess the health effects of embedded metal fragments, we surgically implanted metal pellets into the gastrocnemius muscles of male Sprague-Dawley rats. Test metals were chosen from a list promulgated by the U.S. Department of Defense as “metals of concern” with respect to embedded fragment wounds and included tungsten, nickel, cobalt, iron, copper, aluminum, lead, and depleted uranium. Tantalum was used as a control metal. Cohorts of the metal-implanted rats were humanely euthanized at 1, 3, 6, and 12-months post-implantation and a variety of tissues collected and analyzed for metal content using inductively coupled plasma-mass spectrometry. Results: With few exceptions, the embedded metal fragments eventually released solubilized metal ions, with the metals deposited in numerous tissues in the rats. Not all of the embedded metals localized to all tissues at significant levels. Copper, iron, and aluminum were not found in statistically significant levels, versus control, in any of the tissues analyzed. The other metals tested all appeared in elevated levels in the kidney which is not surprising since previous research has shown that they are also excreted in the urine at appreciable amounts. Tungsten and nickel were found in only a small number of tissues, tungsten in spleen, and nickel in liver and testes. Cobalt, lead, and depleted uranium showed the widest distribution with significant levels in liver, spleen, testes, lung, tibia, fibula, and femur. Conclusion: In this study, we showed that embedded metal fragments, such as those suffered in a shrapnel wound, could solubilize and metals become deposited in tissues far from the original site of implantation. Tissue deposition was metal-specific and many of the metals were found to cross the blood-testes barrier and were also found in bone. Since standard surgical guidance recommends leaving embedded fragments in place except for certain circumstances, this report will expand the understanding of tissue deposition of the solubilized metals and will hopefully aid healthcare professionals in developing long-term treatment strategies for dealing with these types of wounds.

Lessons Learned and Unsolved Public Health Problems After Large-Scale Disasters

1997 ◽  
Vol 12 (2) ◽  
pp. 49-60 ◽  
Author(s):  
Victor S. Koscheyev ◽  
Gloria R. Leon ◽  
Ian A. Greaves
Keyword(s):  
Public Health ◽  
Health Effects ◽  
Psychological Health ◽  
Disaster Response ◽  
Large Scale ◽  
Health Problems ◽  
Lessons Learned ◽  
The Body ◽  
Nuclear Facilities

AbstractBackground:This paper examines the considerable medical and psychological problems that ensue after disasters in which massive populations are affected for extended and sometimes unknown time periods. The organization of disaster response teams after large-scale disasters is based on experiences as a medical specialist at Chernobyl immediately after this catastrophe. Optimal ways of dealing with the immediate medical and logistical demands as well as long-term public health problems are explored with a particular focus on radiation disasters. Other lessons learned from Chernobyl are explained.Issues:Current concerns involve the constant threat of a disaster posed by aging nuclear facilities and nuclear and chemical disarmament activities. The strategies that have been used by various groups in responding to a disaster and dealing with medical and psychological health effects at different disaster stages are evaluated. The emergence of specialized centers in the former Soviet Union to study long-term health effects after radiation accidents are described. Worldwide, there has been relatively little attention paid to mid- and long-term health effects, particularly the psychological stress effects. Problems in conducting longitudinal health research are explored.Recommendations:The use of a mobile diagnostic and continuously operating prehospital triage system for rapid health screening of large populations at different stages after a large-scale disaster is advisable. The functional systems of the body to be observed at different stages after a radiation disaster are specified. There is a particularly strong need for continued medical and psychosocial evaluation of radiation exposed populations over an extended time and a need for international collaboration among investigators.

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