scholarly journals Determinants Of Perinatal Mortality In Bahir Dar Town Governmental Health Institutions, Northwest, Ethiopia, 2019: Prospective Unmatched Case Control Study

2019 ◽  
Author(s):  
kebadnew mihretie ◽  
DANIEL TAREKEGN WOREDE ◽  
TAYE ABUHAY
Keyword(s):  
Protective Factors ◽  
Perinatal Mortality ◽  
Case Control Study ◽  
Tertiary Education ◽  
Case Control ◽  
Neonatal Deaths ◽  
Health Institutions ◽  
Early Neonatal Deaths ◽  
Control Study

Abstract Background: Perinatal mortality is defined as fetal death after 28 weeks of gestation and newborn death within seven days. Globally, more than 2.6 million stillbirths and over 2.7 million early neonatal deaths are estimated to occur each year. Each day an estimated 7,300 newborns die from complication during pregnancy, child birth and further neonatal causes and 7000 stillbirth, half of this occurs after labor had started. Almost all (98%) takes place in developing countries and the magnitude of perinatal mortality in the study area was 44 per 1000 pregnancy. Objective: The objective of this study was to identify determinants of perinatal mortality in Bahirdar town governmental health institutions. Methods: Institutional based unmatched case control study was conducted .Cases were stillbirths and early neonatal deaths and controls were live births that were survived the first seven days after delivery. A total of 459 participants were involved in this study (153 cases and 306 controls) .Pretested, structured questioner with face to face interview was conducted and some data were also extracted using checklist from their medical records. Multivariable logistic regression analysis was done to analyze the data. A p-value of <0.05 was considered as significant at 95% confidence interval and the strength of association was measured using odds ratio. Results: Antepartum hemorrhage (AOR 2.55,95%CI;1.23-5.26), obstructed labour (AOR 3.11,95% CI; 2.00-8.38), prematurity (AOR 3.29,95% CI;1.86-5.81), first delay (AOR 2.61,95% CI;1.56-4.39) and second delay (AOR 2.75,95% CI;1.49-5.11) were the determinants of perinatal mortality that increase risk of perinatal death. Whereas partograph use (AOR 0.24, 95% CI; 0.14-0.42) and tertiary education (AOR 0.35, 95% CI; 0.17-0.71) were found to be protective factors for perinatal mortality. Conclusion and Recommendation:The determinants of perinatal mortality were antepartum hemorrhage,prematurity, obstructed labour, first delay and second delay that were increase the risk of perinatal mortality whereas maternal tertiary education and partograph use during labour follow up were the protective factors. But the risk factors were easily identifiable and manageable with the existing health care services while health partograph use in labour follow up and educating females to tertiary education level is better, first and second delay need to avoided during

scholarly journals The magnitude of perinatal mortality rate and associated risk factors among deliveries at Dilla University Referral Hospital, Southern Ethiopia: A case-control study

2022 ◽  
Vol 9 (1) ◽  
Author(s):  
Kefale Lelamo Legu ◽  
Alemu Tamiso Debiso ◽  
Kaleb Mayisso Rodamo
Keyword(s):  
Risk Factors ◽  
Mortality Rate ◽  
Perinatal Mortality ◽  
Case Control Study ◽  
Case Control ◽  
Neonatal Deaths ◽  
Perinatal Mortality Rate ◽  
Associated Risk Factors ◽  
Early Neonatal Deaths ◽  
Control Study

The perinatal mortality rate is the sum of stillbirths and early neonatal deaths divided by the number of pregnancies of seven or more months’ duration. In Ethiopia, the death rate was 33 deaths/1000 total births in 2016. We aimed to identify the perinatal mortality rate and associated risk factors among deliveries in Dilla University Referral Hospital; January, 2016 - December, 2018. A hospital based retrospective case-control study was conducted using subgroup binary logistic regression analysis including 138 cases and 296 control group. The proportion of hospital perinatal deaths was 30% with 90% of the deaths were occurred as a result of stillbirths and antepartum hemorrhage. Adjusted odds ratios revealed that history of still birth, very low birth weight, short interval and nonuse of partograph found to be independent predictors of both stillbirths and early neonatal deaths besides to pregnancy induced hypertension and antepartum hemorrhage. The risk of perinatal mortality may be increased by not treating chronic illnesses, obstetrics complications and risk factors causing low birth weight as well as short birth intervals and not using partograph during labour.

scholarly journals A case-control study of risk factors for fetal and early neonatal deaths in a tertiary hospital in Kenya

2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Faith Yego ◽  
Catherine D’Este ◽  
Julie Byles ◽  
Paul Nyongesa ◽  
Jennifer Stewart Williams
Keyword(s):  
Risk Factors ◽  
Case Control Study ◽  
Tertiary Hospital ◽  
Case Control ◽  
Neonatal Deaths ◽  
Early Neonatal Deaths ◽  
Control Study

scholarly journals Determinants of short birth interval among women in South Gondar, Ethiopia: community-based unmatched case-control study

2021 ◽  
Vol 79 (1) ◽  
Author(s):  
Gedefaye Nibret Mihretie ◽  
Fentahun Yenealem Beyene ◽  
Bekalu Getnet Kassa ◽  
Alemu Degu Ayele ◽  
Tewachew Muche Liyeh ◽  
...  
Keyword(s):  
Antenatal Care ◽  
Birth Interval ◽  
Case Control Study ◽  
Birth Spacing ◽  
Case Control ◽  
Community Based ◽  
Short Birth Interval ◽  
South Gondar ◽  
Control Study

Abstract Background The effect of short birth interval on socio-economic, negative maternal and child health outcomes remains common in developing countries. This study aimed to assess determinants of short birth interval among reproductive age women, who gave birth in health institution for last six-month in South Gondar, Ethiopia 2019. Methods Community-based unmatched case control study design was conducted from February 1 to March 30, 2019. Sample size of 150 was included by simple random sampling technique. The data was collected by semi-structured and pre-tested face to face interviewer-administered questionnaire from selected respondent. The collected data was entered with Epi-Data version 3.1 and analyzed by using SPSS version 23 software. Bivariate and multivariable analyses were used to examine the association. Odds ratio, 95% CI and P-value < 0.05 were used to determine the statistical association. Result The mean age of the respondents was 32.42 (SD ± 5.14) and 35.12 (SD ± 5.86) for cases and controls, respectively. Mothers not used contraceptives (AOR = 6.29, 95% CI (1.95, 20.24)), participants who had ≤2 alive children (AOR = 5.57, 95% CI (1.47, 21.13)), mothers who breast fed less than 24 months (AOR = 3.42, 95% CI (1.38, 8.46)), husband decision on contraceptives utilization (AOR = 2.69,95% CI (1.05,6.88)) and mothers who did not have history of antenatal care follow up (AOR = 3.52, 95% CI (1.27, 9.75)) were associated with short birth interval. Conclusion The optimum birth spacing plays a vital role in decreasing fertility and the morbidity and mortality of mothers and children. Thus, providing health information on the benefit of breast feeding, follow-up of antenatal care during pregnancy, use of contraceptives after delivery and encouraging mothers to make decisions about their own health and use of contraceptives to optimize birth spacing for rural communities.

scholarly journals Laminoplasty with selective fusion at unstable segment versus laminectomy with fusion for multilevel cervical myelopathy: a case‐control study

2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Lin Du ◽  
Yanzheng Gao ◽  
Changqing Zhao ◽  
Tangjun Zhou ◽  
Haijun Tian ◽  
...  
Keyword(s):  
Symptom Severity ◽  
Cervical Myelopathy ◽  
Case Control Study ◽  
Case Control ◽  
Axial Symptom ◽  
Segmental Instability ◽  
Neurologic Status ◽  
Multilevel Cervical Myelopathy ◽  
Control Study

Abstract Background Segmental cervical instability is a risk factor for the progression of osteophytic bone spurs and development of myelopathy, and is treated as a relative contraindication of cervical laminoplasty. The aim of this study was to compare laminoplasty with selective fixation (LPSF) versus laminectomy with fusion (LCF) in patients with multilevel cervical myelopathy accompanied by segmental instability. Methods A case-control study was conducted by reviewing data from 63 patients who underwent LPSF (n = 30) or LCF (n = 33). Cervical alignment, range of motion (ROM), neurologic status and axial symptom severity pre-operation, 3-days after operation, and at the final follow-up (minimum 24 months) were measured and compared between groups. Results Postoperation, patients in the LPSF group lost 31.1 ± 17.3 % of cervical lordosis and 43.2 ± 10.9 % cervical ROM while patients in the LCF group lost 5.7 ± 8.2 % and 67.9 ± 15.5 %, respectively. Both LPSF and LCF groups significantly improved neurologic status and axial symptom severity at the final follow-up with similar between-group results(P > 0.05). Blood loss, operation time, hospital stay, and medical cost in the LPSF group were significantly less than in the LCF group(P < 0.05). Conclusions In 2 years of clinical observation, LPSF was effective in maintaining the stability of the cervical spine with less sacrifice of mobility and surgical trauma for multilevel myelopathy with segmental instability compared to LCF.

Gastric cellular turnover and the development of atrophy after 31 years of follow-up: a case-control study

1999 ◽  
Vol 94 (8) ◽  
pp. 2109-2114 ◽  
Author(s):  
S. F. Moss ◽  
J. Valle ◽  
A. M. Abdalla ◽  
S. Wang ◽  
M. Siurala ◽  
...  
Keyword(s):  
Case Control Study ◽  
Case Control ◽  
Cellular Turnover ◽  
Control Study

Risk factors for perinatal mortality: a case control study from Thiruvananthapuram, Kerala, India

2017 ◽  
Vol 6 (6) ◽  
pp. 2452 ◽  
Author(s):  
Mayadevi Brahmanandan ◽  
Lekshmi Murukesan ◽  
Bindu Nambisan ◽  
Shaila Salmabeevi
Keyword(s):  
Risk Factors ◽  
Mortality Rate ◽  
Perinatal Mortality ◽  
Case Control Study ◽  
Gestational Hypertension ◽  
Significant Risk ◽  
Case Control ◽  
Maternal Risk ◽  
Perinatal Mortality Rate ◽  
Control Study

Background: The greatest risks to life are in its very beginning. Although a good start in life begins well before birth, it is just before, during, and in the very first hours and days after birth that life is most at risk. This prospective case control study was designed on maternal risk factors for perinatal mortality.Methods: This was a case control study conducted in the Department of Obstetrics and Gynecology and Department of Paediatrics, Medical College Trivandrum for one year period in 2004-2005. The cases were all the fresh and macerated still births and early neonatal death cases during the study period. The controls were chosen as the next delivery entry in the OR register.Results: During this period, the total number of deliveries was 14,796 and there were 431 perinatal deaths. The perinatal mortality rate was 29.12. This was much higher compared to Kerala’s perinatal mortality rate of 10, the reason being that the study is conducted in a tertiary referral hospital with one of the best new born care nurseries and a large number of referrals. The most significant risk factors for perinatal mortality were low socio-economic status, referrals, late registration, prematurity, low birth weight, intra-uterine growth restriction, maternal diseases like gestational hypertension and gestational diabetes and intrapartum complications like abruption.Conclusions: Perinatal mortality rate serves as the most sensitive index of maternal and neonatal care. Good antenatal care and prevention of preterm birth may play a key role in further reduction of PMR.

scholarly journals IL-10 Promoter Genetic Polymorphisms and Risk of Kawasaki Disease in Taiwan

2011 ◽  
Vol 30 (1) ◽  
pp. 51-59 ◽  
Author(s):  
Kai-Sheng Hsieh ◽  
Tsung-Jen Lai ◽  
Yu-Tung Hwang ◽  
Ming-Wei Lin ◽  
Ken-Pen Weng ◽  
...  
Keyword(s):  
Kawasaki Disease ◽  
Case Control Study ◽  
Serum Levels ◽  
High Plasma ◽  
Case Control ◽  
Healthy Children ◽  
Increased Risk ◽  
Family Based ◽  
Control Study

Kawasaki disease (KD) is the most common cause of pediatric acquired heart disease. KD patients have spontaneously high plasma/serum levels of IL-10 during the acute phase. Therefore, two independent studies were carried out to investigate the association between genetic variants in IL-10 promoter (−1082, −819, and −592) and risk of KD. A total of 134 trios were included for the family-based association study. A significantly preferential transmission of the C allele at loci −819 T > C and −592 A > C for KD cases was observed (Ppermutation= 0.029 and Ppermutation= 0.034, respectively). There was a significant increase in the transmission of haplotype CC (p= 0.016) at the above two loci (OR, 1.632; 95% CI, 1.090–2.443; Ppermutation= 0.019). We also carried out a follow-up case-control study that included 146 KD cases and 315 unrelated healthy children. {The haplotype CC (−819, −592) showed an increased risk of KD (but statistically non-significant; OR, 1.332; 95% CI, 0.987–1.797;p= 0.061). In diplotype analysis, a trend was found between number of CC haplotype and risk of KD (but non-significant,p= 0.061). In conclusion, CC genotype and CC/CC diplotype at IL-10-819T > C and −592A > C were significantly associated with risk of KD in case-parent trio study, which were replicated partially in our follow-up case-control study.

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