scholarly journals Cutaneous Leishmaniasis A Neglected Tropical Disease: Community Knowledge, Attitude And Practices In An Endemic Area, Northwest Ethiopia

2019 ◽  
Author(s):  
Helina Fikre Tamiru ◽  
Yohana James Mashalla ◽  
Rezika Mohammed ◽  
Gloria Thupayagale Tshweneagae
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Perceived Control ◽  
Neglected Tropical Diseases ◽  
Descriptive Analysis ◽  
Numerical Data ◽  
Northwest Ethiopia ◽  
Cross Sectional ◽  
Awareness Campaigns ◽  
Modern Treatment ◽  
The Impact

Abstract BackgroundCutaneous leishmaniasis is one of the neglected tropical diseases in the Ethiopian highlands and studies on assessment of knowledge, attitude and practice of the community in endemic areas are scanty. The study aimed to assess the knowledge, attitude towards cutaneous leishmaniasis and treatment seeking practices in people living in the endemic highlands areas in the Northwest, Ethiopia and provide evidence-based information to guide development of appropriate interventions to reduce the impact of cutaneous leishmaniasis on communities. Methods Quantitative cross-sectional study was conducted in cutaneous leishmaniasis endemic districts (woredas) using a semi structured questionnaires. Households were randomly selected according to probability proportional to size of households in each enumeration area. Systematic random sampling of eligible households was based on the number of households recorded during listing of households. Descriptive statistics was used to describe numerical data, organise and summarise the data in a manner that gave meaning to the numerical form. Frequency tables were used to show descriptive analysis and regression analysis was used to determine correlation between variables.Results While the community knew about cutaneous leishmaniasis knowledge gaps on how the disease is transmitted prevented and prevention were found. Communities perceived cutaneous leishmaniasis a serious disease because of its impact on individuals and expressed positive experiential attitude towards traditional treatment because of easy accessibility. Participants expressed negative experiential attitude and perceived control towards modern treatment because of inaccessibility and distance from where modern treatment is provided. ConclusionPriority should be given to primary prevention and appropriate awareness campaigns on lesion recognition, prevention. Information on modern treatment should be intensified.

scholarly journals Cutaneous leishmaniasis a neglected tropical disease: community knowledge, attitude and practices in an endemic area, Northwest Ethiopia

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Helina Fikre Tamiru ◽  
Yohana James Mashalla ◽  
Rezika Mohammed ◽  
Gloria Thupayagale Tshweneagae
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Rural Areas ◽  
Neglected Tropical Diseases ◽  
Numerical Data ◽  
Northwest Ethiopia ◽  
Duration Of Treatment ◽  
Cross Sectional ◽  
Awareness Campaigns ◽  
Modern Treatment ◽  
The Impact

Abstract Background Cutaneous leishmaniasis is one of the neglected tropical diseases in the Ethiopian highlands and studies on assessment of knowledge, attitude and practice of the community in endemic areas are scanty. The study aimed to assess the knowledge, attitude towards cutaneous leishmaniasis and treatment seeking practices in people living in the endemic highlands areas in the Northwest, Ethiopia and to provide evidence-based information to guide development of appropriate interventions to reduce the impact of cutaneous leishmaniasis on communities. Methods Quantitative cross-sectional study was conducted in cutaneous leishmaniasis endemic districts (woredas) using a semi structured questionnaire. Households were randomly selected according to probability proportional to size of households in each enumeration area. Systematic random sampling of eligible households was based on the number of households recorded during listing of households. Descriptive statistics was used to describe numerical data, organise and summarise the data in a manner that gave meaning to the numerical form. Frequency tables were used to show descriptive analysis and regression analysis was used to determine correlation between variables. Results Majority of respondents 321(78.7%) lived in rural areas, age ranged between 18 and 85 years and most were farmers. Illiteracy was high (47.6%) among respondents and majority 358(87.8%) had seen patients with CL. Less than quarter (21.6%) had heard about sand flies and knowledge on the peak transmission period was low (46.3%). About 192 (47.1%) of the respondents indicated disfiguring lesions were the major clinical presentations, less than half 55(27.5%) of urban residents believed CL was treatable compared to 145(72.5%) of rural residents (P < 0.001). Traditional medicines were indicated as best treatment option by 209(51.2%) compared to 114(27.9%) for modern treatment. Major factors influencing treatment options included accessibility to treatment facilities, distance and short duration of treatment. Participants expressed negative experiential attitude and perceived control towards modern treatment because of inaccessibility and distance from where modern treatment is provided. Conclusion Priority should be given to primary prevention and appropriate awareness campaigns on lesion recognition. Information on modern treatment should be intensified.

scholarly journals CUTANEOUS LEISHMANIASIS A NEGLECTED TROPICAL DISEASE: COMMUNITY KNOWLEDGE, ATTITUDE AND PRACTICES IN AN ENDEMIC AREA, NORTHWEST ETHIOPIA

2019 ◽  
Author(s):  
Helina Fikre Tamiru ◽  
Yohana James Mashalla ◽  
Rezika Mohammed ◽  
Gloria Thupayagale Tshweneagae
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Rural Areas ◽  
Neglected Tropical Diseases ◽  
Numerical Data ◽  
Northwest Ethiopia ◽  
Duration Of Treatment ◽  
Cross Sectional ◽  
Awareness Campaigns ◽  
Modern Treatment ◽  
The Impact

Abstract Background Cutaneous leishmaniasis is one of the neglected tropical diseases in the Ethiopian highlands and studies on assessment of knowledge, attitude and practice of the community in endemic areas are scanty. The study aimed to assess the knowledge, attitude towards cutaneous leishmaniasis and treatment seeking practices in people living in the endemic highlands areas in the Northwest, Ethiopia and provide evidence-based information to guide development of appropriate interventions to reduce the impact of cutaneous leishmaniasis on communities. Methods Quantitative cross-sectional study was conducted in cutaneous leishmaniasis endemic districts (woredas) using a semi structured questionnaires. Households were randomly selected according to probability proportional to size of households in each enumeration area. Systematic random sampling of eligible households was based on the number of households recorded during listing of households. Descriptive statistics was used to describe numerical data, organise and summarise the data in a manner that gave meaning to the numerical form. Frequency tables were used to show descriptive analysis and regression analysis was used to determine correlation between variables. Results Majority of respondents 321(78.7%) lived in rural areas, age ranged between 18 and 85 years and most were farmers. Illiteracy was high (47.6%) among respondents and majority 358(87.8%) had seen patients with CL. Less than quarter (21.6%) had heard about sand flies and knowledge on the peak transmission period was low (46.3%). About 192 (47.1%) of the respondents indicated disfiguring lesions were the major clinical presentations, less than half 55(27.5%) of urban residents believed CL was treatable compared to 145(72.5%) of rural residents (P < 0.001). Traditional medicines were indicated as best treatment option by 209(51.2%) compared to 114(27.9%) for modern treatment. Major factors influencing treatment options included accessibility to treatment facilities, distance and short duration of treatment. Participants expressed negative experiential attitude and perceived control towards modern treatment because of inaccessibility and distance from where modern treatment is provided. Conclusion Priority should be given to primary prevention and appropriate awareness campaigns on lesion recognition, prevention. Information on modern treatment should be intensified.

scholarly journals Cutaneous Leishmaniasis A Neglected Tropical Disease: Community Knowledge, Attitude And Practices In An Endemic Area, Northwest Ethiopia

2019 ◽  
Author(s):  
Helina Fikre Tamiru ◽  
Yohana James Mashalla ◽  
Rezika Mohammed ◽  
Gloria Thupayagale Tshweneagae
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Rural Areas ◽  
Neglected Tropical Diseases ◽  
Numerical Data ◽  
Northwest Ethiopia ◽  
Duration Of Treatment ◽  
Cross Sectional ◽  
Awareness Campaigns ◽  
Modern Treatment ◽  
The Impact

Abstract Background Cutaneous leishmaniasis is one of the neglected tropical diseases in the Ethiopian highlands and studies on assessment of knowledge, attitude and practice of the community in endemic areas are scanty. The study aimed to assess the knowledge, attitude towards cutaneous leishmaniasis and treatment seeking practices in people living in the endemic highlands areas in the Northwest, Ethiopia and provide evidence-based information to guide development of appropriate interventions to reduce the impact of cutaneous leishmaniasis on communities. Methods Quantitative cross-sectional study was conducted in cutaneous leishmaniasis endemic districts (woredas) using a semi structured questionnaires. Households were randomly selected according to probability proportional to size of households in each enumeration area. Systematic random sampling of eligible households was based on the number of households recorded during listing of households. Descriptive statistics was used to describe numerical data, organise and summarise the data in a manner that gave meaning to the numerical form. Frequency tables were used to show descriptive analysis and regression analysis was used to determine correlation between variables. Results Majority of respondents 321(78.7%) lived in rural areas, age ranged between 18 and 85 years and most were farmers. Illiteracy was high (47.6%) among respondents and majority 358(87.8%) had seen patients with CL. Less than quarter (21.6%) had heard about sand flies and knowledge on the peak transmission period was low (46.3%). About 192 (47.1%) of the respondents indicated disfiguring lesions were the major clinical presentations, less than half 55(27.5%) of urban residents believed CL was treatable compared to 145(72.5%) of rural residents (P < 0.001). Traditional medicines were indicated as best treatment option by 209(51.2%) compared to 114(27.9%) for modern treatment. Major factors influencing treatment options included accessibility to treatment facilities, distance and short duration of treatment. Participants expressed negative experiential attitude and perceived control towards modern treatment because of inaccessibility and distance from where modern treatment is provided. Conclusion Priority should be given to primary prevention and appropriate awareness campaigns on lesion recognition, prevention. Information on modern treatment should be intensified.

scholarly journals 936. Evaluating the Impact of Polypharmacy on Virologic Success in People with HIV

2020 ◽  
Vol 7 (Supplement_1) ◽  
pp. S501-S502
Author(s):  
Humberto R Jimenez ◽  
Naana Boachie ◽  
Sangwon Park ◽  
Jin Suh
Keyword(s):  
Hiv Transmission ◽  
Virologic Failure ◽  
Descriptive Analysis ◽  
Virologic Response ◽  
Transmission Risk ◽  
Pill Burden ◽  
Cross Sectional ◽  
Hiv Rna ◽  
Aids Diagnosis ◽  
The Impact

Abstract Background As people with HIV (PWH) have experienced reductions in antiretroviral pill burden, there has been an increase in medications to manage non-AIDS-related co-morbidities. Previous studies have linked virologic failure to an increased pill burden. This study assessed whether polypharmacy and other variables affect success of HIV management in our population. Methods A retrospective, cross-sectional analysis of PWH receiving care at a Ryan White-funded clinic in New Jersey was performed. Eligible patients were ≥18 years old, had ≥2 visits in 2019 and were receiving antiretroviral therapy (ART). The primary endpoints were to determine the effect polypharmacy (defined as 5 or more non-ART pills per day) on virologic response rates (HIV RNA &lt; 200 copies/mL). Secondary endpoints accounted for the impact of age, gender, race/ethnicity, HIV transmission risk factor, and AIDS diagnosis on virologic response. A descriptive analysis of comorbidities and medication classes was also completed. Logistic regression, chi square and student’s t test were used for statistical analysis. Results 964 patients were included in the analysis, with 355 (37%) meeting the criteria for polypharmacy. Most patients were male (60%) and the mean age was 49 years of age. The racial/ethnic breakdown was 46% Hispanic, 45% Black and 8% White. Polypharmacy was associated with higher rates of virologic success compared to those with a lower pill burden: 94% vs 86% had an HIV RNA &lt; 200 copies/mL (P=0.0003), respectively. ART pill burden was statistically, but not clinically higher among those with polypharmacy (1.34 vs 1.45, P=0.025). Virologic response was found to be higher among Hispanics and Whites in comparison to Black patients (OR 2.2, CI 1.4-3.5 and 3.0, CI 1.1-8.2). Patients with an AIDS diagnosis were less likely to achieve virologic response (OR 0.64, CI 0.42-0.99). Conclusion Patients with polypharmacy were more likely to achieve virologic success than paitents with a low pill burden in our population. Disclosures Humberto R. Jimenez, PharmD, BCPS, AAHIVP, Gilead (Speaker’s Bureau)

scholarly journals Investigating the business performance on the financial well-being of the Government retirees

2021 ◽  
Vol 124 ◽  
pp. 03006
Author(s):  
Abdul Mutalib Embong ◽  
Norzamziah Afzainizam ◽  
Mariati Norhashim ◽  
Amirsaman Ahmadi
Keyword(s):  
Business Performance ◽  
Profile Analysis ◽  
Descriptive Analysis ◽  
Well Being ◽  
The Elderly ◽  
Population Ageing ◽  
Ageing Population ◽  
Cross Sectional ◽  
The Government ◽  
The Impact

Population ageing; where there is growth in the percentage of older persons in the population; is becoming a worldwide phenomenon due to better healthcare and lower birth rates. The phenomenon of population ageing brings with it both challenges and opportunities. The challenges of an ageing population include social, health and economic support of the elderly. Malaysia is recognizing the need to address this issue of financially supporting an ageing population. The purpose of the paper was to investigate the impact of business on the financial well-being (FWB) of the ageing, specifically the government retirees. A questionnaire-based survey was conducted among retirees who were in business throughout Malaysia that employed a cross sectional design. Forty-one respondents were successfully interviewed. Statistical procedures for the analyses included descriptive analysis and a profile analysis using scatterplot on the perceived business performance vs financial well-being. The survey revealed that the majority of the respondents operated business in the services, trade or retail industries which were set up and fully owned by themselves. Resource wise, the majority had very low financial capital, human capital and social capital. The study provides some empirical evidence that the retirees in business may be categorized into opportunity driven and necessity driven groups. The paper concludes that there is a need to find alternative income generation methods for the necessity driven group. Making paid work accessible to the elderly must be urgently put on the national agenda.

Persepsi Pesan Gambar Pada Bungkus Rokok Dan Perilaku Merokok Remaja Di Kota Medan

2020 ◽  
Vol 2 (2) ◽  
pp. 107
Author(s):  
Fauziah Nasution
Keyword(s):  
Descriptive Analysis ◽  
Smoking Behaviour ◽  
Primary Data ◽  
Research Approach ◽  
Cross Sectional ◽  
Product Packaging ◽  
Quit Smoking ◽  
The Government ◽  
The Impact ◽  
Cigarette Packs

<p><strong><em>Introduction:</em></strong> <em>The picture message policy on cigarette packets is regulated in Permenkes No. 28 of 2013 concerning the Inclusion of Warnings and Health Information on Tobacco Product Packaging. The purpose of the inclusion of pictorial health warnings (PKB) on cigarette packs is to prevent adolescents from smoking. By looking at the frightening picture on PKB, it hoped that young smokers would be motivated to quit smoking</em><em>. <strong>Method</strong>: This study used a quantitative research approach with a cross-sectional design (cross-sectional) using primary data, this research conducted in Medan City. During January - June 2019. The population in this study were adolescents aged 18-23 years. The sample of this study was 215 teenagers. Data analysis used cross-tabulation descriptive analysis than presented in the form of a frequency distribution table using SPSS 22. <strong>Results</strong>: The results of this study indicate that the majority of respondents have smoking behaviour in the 19-20 year age group. The majority of respondents stated that they smoke 1-5 cigarettes a day. Teens who stated that they were not afraid of the impact of picture messages on cigarette packs had a 3,939 times risk of smoking compared to adolescents who expressed fear of the impact of picture messages on cigarette packs <strong>Conclusion</strong>: It hoped that the government could expand the picture message on cigarette packets to increase the desire to quit smoking and reduce the number of smokers in Indonesia. The image message on cigarette packs must be enlarged in order to reduce smoking behaviour in adolescents.</em></p>

scholarly journals Prevalence, Intensity, and Associated Factors of Schistosoma mansoni among School Children in Northwest Ethiopia

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Ayalew Jejaw Zeleke ◽  
Ayenew Addisu ◽  
Yalewayker Tegegne
Keyword(s):  
Risk Factors ◽  
Schistosoma Mansoni ◽  
Grade Level ◽  
Neglected Tropical Diseases ◽  
Multivariate Logistic Regression Analysis ◽  
Sampling Technique ◽  
Northwest Ethiopia ◽  
Moderate Intensity ◽  
Cross Sectional ◽  
Study Participants

Background. Schistosomiasis is one of the Neglected Tropical Diseases in Ethiopia, and its burden may show variations from time to time across different regions. Thus, this study was aimed at determining the prevalence, intensity, and associated risk factors of Schistosoma mansoni (S. mansoni) among schoolchildren in Northwest Ethiopia. Methods. A school-based cross-sectional study was conducted. A multistage sampling technique was used to select the study participants. Stool specimens were collected and examined using two-slide Kato-Katz method. Data were analyzed using SPSS version 20 software. Multivariate logistic regression analysis was used to identify risk factors. p values less than 0.05 were taken as statistically significant. Result. A total of 786 schoolchildren were participated in this study. The prevalence of S. mansoni was 33.5%. The mean egg count of the parasite among the infected study participants was 523.665 eggs per gram (epg) of stool. Thirty-seven, 42, and 21 percent of the study participant’s infection were due to light, moderate, and heavy infection intensities, respectively. Age of 8-11 years old ( AOR = 1,687 , 95 % CI = 1.163 , 2.892 ), 5th-8th grade level ( AOR = 2.280 , 95 % CI = 1.348 , 3.856 ), residing in Chuahit District ( AOR = 95.559 , 95 % CI = 12.945 , 705.419 ), and using untreated water for domestic supply ( AOR = 1.724 , 95 % CI = 1.457 , 2.148 ) were found to be risk factors for S. mansoni infection. Conclusion. High prevalence of S. mansoni and relatively higher proportion of moderate intensity of infection in this study imply that schistosomiasis is still one of the major public health problems in Northwest Ethiopia. It is also highlighted that study sites, provision of water supply, age, and grade level of the schoolchildren were identified as a risk factors for the disease.

scholarly journals Brazilian vascular surgeons experience during the coronavirus (COVID-19) pandemic

Vascular ◽  
2020 ◽  
pp. 170853812095496
Author(s):  
Rafael D Malgor ◽  
Marcone Lima Sobreira ◽  
Nicolas J Mouawad ◽  
Adam P Johnson ◽  
Max V Wohlauer ◽  
...  
Keyword(s):  
Social Media ◽  
Vascular Surgery ◽  
Task Force ◽  
Descriptive Analysis ◽  
Healthcare Providers ◽  
Coping Mechanisms ◽  
Cross Sectional ◽  
Brief Cope ◽  
Anxiety Levels ◽  
The Impact

Background The COVID-19 pandemic has made a significant impact on all spheres of society. The objective of this study was to examine the impact of COVID-19 on the practices, finances, and social aspects of Brazilian vascular surgeons’ lives. Methods This is a descriptive analysis of the responses from Brazilian vascular surgeons to the cross-sectional anonymous Society for Vascular Surgery Wellness Task Force Pandemic Practice, Anxiety, Coping, and Support Survey for Vascular Surgeons disseminated 14–24 April 2020. Survey dissemination in Brazil occurred mainly via the Brazilian Society of Angiology and Vascular Surgery (SBACV) and social media. The survey evaluated the impact of the COVID-19 pandemic on vascular surgeons’ lives by assessing COVID-19-related stressors, anxiety using theGeneral Anxiety Disorder (GAD)-7 scale, and coping strategies using the Brief Coping Orientation to Problems Experienced (Brief-COPE) inventory. Results A total of 452 responses were recorded from Brazil, with 335 (74%) respondents completing the entire survey. The majority of respondents were males ( N = 301, 67%) and practiced in an urban hospitals. The majority of respondents considered themselves at high risk to be infected with COVID-19 ( N = 251, 55.8%), and just over half the respondents noted that they had adequate PPE at their primary hospital ( N = 171, 54%). One hundred and nine (35%) surgeons confirmed that their hospitals followed professional surgical society guidelines for prioritizing surgeries during the pandemic. At the time of the survey, only 33 (10%) surgeons stated they have pre-operative testing of patients for COVID-19 available at their hospital. Academic vascular surgeons reported being redeployed more often to help with other non-vascular duties compared to community-based or solo practitioners (43% vs. 30% vs. 21% respectively, P = .01). Severe anxiety due to pandemic-related financial concerns was similar in those surgeons practicing solo compared to those in community- or academic-based/group practice (46% vs. 38% vs. 22%; P = .54). The respondents reported their anxiety levels as mild based on the stressors investigated instead of moderate-severe (54% vs. 46%; P = .04). Social media was utilized heavily during the pandemic, with video gatherings being the most commonly used tool (76%). Self-distraction (60%) and situational acceptance (81%) were the most frequently reported coping mechanisms used among Brazilian vascular surgeons. Conclusion The COVID pandemic has greatly affected healthcare providers around the world. At the time of this survey, Brazilian vascular surgeons are reporting low anxiety levels during this time and are using mostly active coping mechanisms.

scholarly journals PO 8505 LEISHMANIASIS IN ANGOLA – AN EMERGING DISEASE?

2019 ◽  
Vol 4 (Suppl 3) ◽  
pp. A47.3-A48
Author(s):  
Sofia Cortes ◽  
André Pereira ◽  
Jocelyne Vasconcelos ◽  
Joana P Paixão ◽  
Joltim Quivinja ◽  
...  
Keyword(s):  
Cutaneous Leishmaniasis ◽  
Neglected Tropical Diseases ◽  
Epidemiological Studies ◽  
Sequencing Analysis ◽  
Vector Borne Disease ◽  
Health Authorities ◽  
African Patient ◽  
Control Programmes ◽  
Vector Borne ◽  
The Impact

BackgroundPoverty, lack of resources, inadequate treatments and control programmes exacerbate the impact of infectious diseases in the developing world. Leishmaniasis is a vector-borne disease that is among the ten major neglected tropical diseases. Although endemic in more than 90 countries, the ones most affected, representing over 90% of new cases, are Bangladesh, Brazil, Ethiopia, India, Kenya, Nepal, and Sudan. In Africa south of the equator, the impact of leishmaniasis is much lower. In several countries, like Angola, little is known about this infectious neglected disease. In the 1970s, a group of Portuguese researchers described three cases of cutaneous leishmaniasis in children from Huambo district and in the 1990s visceral leishmaniasis was diagnosed in an African patient. More recently a canine survey in Luanda revealed two Leishmania-infected dogs.After some suspected cases of human cutaneous leishmaniasis in Huambo region in 2017, the Angola health authorities and the Instituto de Higiene e Medicina Tropical (IHMT), Lisbon, Portugal, established a collaboration to analyse samples from some suspected cases.MethodsThree paraffin-embedded human skin samples from dermatological lesions were sent to IHMT for molecular analysis. After DNA extraction, PCR was performed by using four protocols with different molecular markers.ResultsOne PCR protocol using a nested approach was positive in two of the samples. Sequencing analysis confirmed Leishmania sp. DNA.ConclusionThis was the first time that suspected human cutaneous samples were screened for leishmaniasis by molecular methods with detection of Leishmania sp. DNA. These preliminary studies highlight the need for higher awareness of health professionals for leishmaniasis clinical forms, to recognise risk factors and the epidemiological features of leishmaniasis in the Huambo province. It would be relevant to perform further epidemiological studies to confirm if this vector-borne disease could be emergent in this country.

scholarly journals Novel transdisciplinary methodology for cross-sectional analysis of snakebite epidemiology at national scale

2021 ◽  
Vol 15 (2) ◽  
pp. e0009023
Author(s):  
Gabriel Alcoba ◽  
Carlos Ochoa ◽  
Sara Babo Martins ◽  
Rafael Ruiz de Castañeda ◽  
Isabelle Bolon ◽  
...  
Keyword(s):  
Large Scale ◽  
Survey Methodology ◽  
Neglected Tropical Diseases ◽  
Animal Health ◽  
Epidemiological Data ◽  
World Health ◽  
Primary Data ◽  
Cross Sectional ◽  
High Resolution Satellite Images ◽  
The Impact

Background Worldwide, it is estimated that snakes bite 4.5–5.4 million people annually, 2.7 million of which are envenomed, and 81,000–138,000 die. The World Health Organization reported these estimates and recognized the scarcity of large-scale, community-based, epidemiological data. In this context, we developed the “Snake-Byte” project that aims at (i) quantifying and mapping the impact of snakebite on human and animal health, and on livelihoods, (ii) developing predictive models for medical, ecological and economic indicators, and (iii) analyzing geographic accessibility to healthcare. This paper exclusively describes the methodology we developed to collect large-scale primary data on snakebite in humans and animals in two hyper-endemic countries, Cameroon and Nepal. Methodology/Principal findings We compared available methods on snakebite epidemiology and on multi-cluster survey development. Then, in line with those findings, we developed an original study methodology based on a multi-cluster random survey, enhanced by geospatial, One Health, and health economics components. Using a minimum hypothesized snakebite national incidence of 100/100,000/year and optimizing design effect, confidence level, and non-response margin, we calculated a sample of 61,000 people per country. This represented 11,700 households in Cameroon and 13,800 in Nepal. The random selection with probability proportional to size generated 250 clusters from all Cameroonian regions and all Nepalese Terai districts. Our household selection methodology combined spatial randomization and selection via high-resolution satellite images. After ethical approval in Switerland (CCER), Nepal (BPKIHS), and Cameroon (CNERSH), and informed written consent, our e-questionnaires included geolocated baseline demographic and socio-economic characteristics, snakebite clinical features and outcomes, healthcare expenditure, animal ownership, animal outcomes, snake identification, and service accessibility. Conclusions/Significance This novel transdisciplinary survey methodology was subsequently used to collect countrywide snakebite envenoming data in Nepal and Cameroon. District-level incidence data should help health authorities to channel antivenom and healthcare allocation. This methodology, or parts thereof, could be easily adapted to other countries and to other Neglected Tropical Diseases.

Sign in / Sign up

Export Citation Format

Share Document