scholarly journals Clinical Report of Six-Month Follow-Up After Cementing PEEK Crown On Molars

2021 ◽  
Author(s):  
Hitomi Kimura ◽  
Koji Morita ◽  
Fumiko Nishio ◽  
Hiroshi Abekura ◽  
Kazuhiro Tsuga
Keyword(s):  
Patient Satisfaction ◽  
Rank Test ◽  
Prosthetic Material ◽  
Clinical Report ◽  
Occlusal Force ◽  
Significance Level ◽  
Masticatory Ability ◽  
Significant Difference ◽  
Cad Cam ◽  
The Difference

Abstract To investigate the therapeutic effect of polyetheretherketone (PEEK) crowns, a six-month clinical study on CAD/CAM-fabricated molar PEEK crowns was conducted. Twenty-three cases of PEEK crowns placed on the molars of 20 subjects (7 males and 13 females, mean age: 60.6 ± 14.4 years) were included in the study. The evaluation items were the condition of the crowns at the time of cementation and after six months, patient satisfaction, masticatory ability, and occlusal force. A Wilcoxon signed-rank test with a significance level of 5% was used to examine the difference in masticatory ability with and without PEEK crowns. The occlusion, margin fit, and contact of all 23 cases at the time of cementing was good. Six months after cementation, there was no crown desorption, no fracture or crack, and no prosthodontics was needed in the 22 cases where one patient dropped out. No wear of the dental antagonist was observed. Patient satisfaction was generally high. There was no significant difference in masticatory ability between the groups with and without PEEK crowns. The subject's occlusal force was within normal range. PEEK crowns on molars are highly therapeutic methods and can be fully used as a crown prosthetic material to replace metal.

scholarly journals Cohort study of the overall survival of patients with pancreatic cancer in a hospital of specialties of Quito-Ecuador in the period 2007–2017

2021 ◽  
Vol 0 (0) ◽  
Author(s):  
Andrés Moreno Roca ◽  
Luciana Armijos Acurio ◽  
Ruth Jimbo Sotomayor ◽  
Carlos Céspedes Rivadeneira ◽  
Carlos Rosero Reyes ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Cohort Study ◽  
Survival Time ◽  
Univariate Analysis ◽  
Rank Test ◽  
Kaplan Meier ◽  
Significant Difference ◽  
Icd 10 ◽  
The Difference ◽  
Clinical Records

Abstract Objectives Pancreatic cancers in most patients in Ecuador are diagnosed at an advanced stage of the disease, which is associated with lower survival. To determine the characteristics and global survival of pancreatic cancer patients in a social security hospital in Ecuador between 2007 and 2017. Methods A retrospective cohort study and a survival analysis were performed using all the available data in the electronic clinical records of patients with a diagnosis of pancreatic cancer in a Hospital of Specialties of Quito-Ecuador between 2007 and 2017. The included patients were those coded according to the ICD 10 between C25.0 and C25.9. Our univariate analysis calculated frequencies, measures of central tendency and dispersion. Through the Kaplan-Meier method we estimated the median time of survival and analyzed the difference in survival time among the different categories of our included variables. These differences were shown through the log rank test. Results A total of 357 patients diagnosed with pancreatic cancer between 2007 and 2017 were included in the study. More than two-thirds (69.9%) of the patients were diagnosed in late stages of the disease. The median survival time for all patients was of 4 months (P25: 2, P75: 8). Conclusions The statistically significant difference of survival time between types of treatment is the most relevant finding in this study, when comparing to all other types of treatments.

scholarly journals PENGARUH LATIHAN KNEE TUCK JUMP DAN LATIHAN HALF SQUAT JUMP TERHADAP KEMAMPUAN SMASH KEDENG DALAM PERMAINAN SEPAKTAKRAW

2020 ◽  
Vol 11 (3) ◽  
pp. 117
Author(s):  
Heriansyah Heriansyah ◽  
Suhartiwi Suhartiwi
Keyword(s):  
Data Analysis ◽  
Random Sampling ◽  
Male Students ◽  
Squat Jump ◽  
Significance Level ◽  
Jump Training ◽  
Analysis Technique ◽  
Significant Difference ◽  
Experiment Method ◽  
The Difference

This study aims to determine the extent of the difference in effect between knee tuck jump and half squat jump training on the ability to smash kedeng in sepaktakraw games. By using the field experiment method. The population used is male students of Southeast Sulawesi SMANKO with a sample of 60 people taken by Proposive random sampling. The data analysis technique used is the t-test at 95% significance level. The results showed that; (1) There is a significant effect of knee tuck jump training on the ability to smash kedeng in sepaktakraw games on Southeast Sulawesi SMANKO students, proven to = 13,446> tt = 2,045. There is a significant effect of half squat jump training on the ability of the Kedeng smash in sepaktakraw games on Southeast Sulawesi SMANKO students, proven to = 10.478> tt = 2.045. There is a significant difference in effect between training on the ability to smash kedeng in sepaktakraw games on Southeast Sulawesi SMANKO students, proven, to = 9,970> tt = 2,000.

scholarly journals The Effect of Bedside Presentations in the Emergency Department on Patient Satisfaction

2011 ◽  
Vol 3 (4) ◽  
pp. 481-486 ◽  
Author(s):  
Craig I. Schranz ◽  
Robert J. Sobehart ◽  
Kiva Fallgatter ◽  
Robert H. Riffenburgh ◽  
Michael J. Matteucci
Keyword(s):  
Emergency Department ◽  
Patient Satisfaction ◽  
Resident Education ◽  
Statistical Significance ◽  
Future Research ◽  
First Year ◽  
Convenience Sample ◽  
Visual Analog Scales ◽  
Significant Difference ◽  
The Difference

Abstract Background Due to increasing time constraints, the use of bedside presentations in resident education has declined. We examined whether patient satisfaction in the emergency department is affected when first-year residents present at the bedside with attendings. Methods We performed an observational, prospective, nonblinded study in the emergency department of a military teaching hospital. We alternately assigned first-year residents to present a convenience sample of 248 patients to the attending physician at the patient's bedside or away from the patient. We measured patient satisfaction by using the Patient Satisfaction Questionaire-18 (PSQ-18), a validated survey instrument that utilizes a Likert scale, and additional nonvalidated survey questions involving Likert and visual analog scales. Results While the median PSQ-18 score of 74 (95% confidence interval [CI], 72–76) was higher for patient satisfaction when residents made bedside presentations than that for standard presentations, 72 (95% CI, 70–74), the difference did not reach statistical significance (P  =  .33). Conclusion There was no significant difference in overall patient satisfaction between residents' bedside presentations and presentations to attendings away from the patient. Although not significant, the differences noted in PSQ-18 subscales of communication, general satisfaction, and interpersonal manner warrant further investigation. Patients did not appear to be uncomfortable with having their care discussed and with having subsequent resident education at the bedside. Future research on patient satisfaction after implementation of standardized bedside teaching techniques may help further elucidate this relationship.

Utility of T2 mapping in the staging of thyroid-associated ophthalmopathy: efficiency of region of interest selection methods

2020 ◽  
Vol 61 (11) ◽  
pp. 1512-1519 ◽  
Author(s):  
Wen Chen ◽  
Hao Hu ◽  
Huan-Huan Chen ◽  
Guo-Yi Su ◽  
Tao Yang ◽  
...  
Keyword(s):  
T2 Mapping ◽  
Region Of Interest ◽  
Roc Curves ◽  
Rank Test ◽  
Selection Methods ◽  
Measuring Time ◽  
Significant Difference ◽  
Thyroid Associated Ophthalmopathy ◽  
Signed Rank Test ◽  
The Difference

Background Discriminating the stage of thyroid-associated ophthalmopathy (TAO) is crucial for the treatment strategy and prognosis prediction. Utility of conventional magnetic resonance imaging in the disease staging is limited. Purpose To investigate the performance of T2 mapping based on different region of interest (ROI) selection methods in the staging of TAO. Material and Methods Thirty-two patients with TAO were retrospectively enrolled. Two radiologists independently measured the T2 relaxation time (T2RT) of extraocular muscles using two different ROIs (hotspot [ROIHS]: T2RT-hot; single-slice [ROISS]: T2RT-mean, T2RT-max, T2RT-min). Independent-samples t test, Wilcoxon signed rank test, Spearman correlation analysis, receiver operating characteristic (ROC) curves analyses, multiple ROC comparisons, and intra-class correlation coefficient (ICC) were used for statistical analyses. Results No significant difference was found in the measuring time between ROIHS and ROISS methods ( P = 0.066). T2RT-mean demonstrated the highest ICC for measurement, followed by T2RT-max and T2RT-min, and T2RT-hot showed the poorest reproducibility. Active TAOs showed significantly higher values for all the T2RTs than inactive mimics (all P < 0.001). Significant positive correlations were found between T2RTs and CAS (all P < 0.005). T2RT-hot and T2RT-max showed significantly higher areas under the curve than that of T2RT-mean ( P = 0.013 and 0.024, respectively), while the difference between T2RT-hot and T2RT-max was not significant ( P = 0.970). Conclusion The T2RTs derived from both ROI selection methods could be useful for the staging of TAO. The results of measuring time, reproducibility, and diagnostic performance suggest that T2RT-max would be the optimal indicator for staging.

scholarly journals Frontal Alpha Complexity of Different Severity Depression Patients

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Lulu Zhao ◽  
Licai Yang ◽  
Baimin Li ◽  
Zhonghua Su ◽  
Chengyu Liu
Keyword(s):  
Neuronal Activity ◽  
Healthy Subjects ◽  
Sample Entropy ◽  
Rank Test ◽  
Mild Depression ◽  
Healthy Group ◽  
Significant Difference ◽  
Entropy Measures ◽  
The Difference ◽  
State Group

Depression is a leading cause of disability worldwide, and objective biomarkers are required for future computer-aided diagnosis. This study aims to assess the variation of frontal alpha complexity among different severity depression patients and healthy subjects, therefore to explore the depressed neuronal activity and to suggest valid biomarkers. 69 depression patients (divided into three groups according to the disease severity) and 14 healthy subjects were employed to collect 3-channel resting Electroencephalogram signals. Sample entropy and Lempel–Ziv complexity methods were employed to evaluate the Electroencephalogram complexity among different severity depression groups and healthy group. Kruskal–Wallis rank test and group t-test were performed to test the difference significance among four groups and between each two groups separately. All indexes values show that depression patients have significantly increased complexity compared to healthy subjects, and furthermore, the complexity keeps increasing as the depression deepens. Sample entropy measures exhibit superiority in distinguishing mild depression from healthy group with significant difference even between nondepressive state group and healthy group. The results confirm the altered neuronal activity influenced by depression severity and suggest sample entropy and Lempel–Ziv complexity as promising biomarkers in future depression evaluation and diagnosis.

Effectiveness of a Basic Education Program on RadiationRelated Health Concerns for Nurses of Public Health and School Health in Japan

2020 ◽  
Author(s):  
Kawasaki HIROMI ◽  
Md Moshiur RAHMAN ◽  
Iwasa MIKA ◽  
Kukinaka CHIEKO
Keyword(s):  
Public Health ◽  
Nuclear Power ◽  
School Health ◽  
Basic Education ◽  
Cognitive Domain ◽  
Rank Test ◽  
Significance Level ◽  
Significant Difference ◽  
Quasi Experimental ◽  
Signed Rank Test

Background: After the Japanese nuclear power plant disaster in 2011, many residents became concerned about health effects of radiation. We aimed to evaluate the effectiveness of a training program for public health and school health nurses to improve their skills and expertise for better support to residents and students. Methods: This was a quasi-experimental study using single-group and pre-post comparison in 2016 in Hiroshima, Kagoshima and Hyogo prefectures of Japan. The educational evaluation was conducted through each sub-item of Bloom’s attainment goals. The evaluation of effectiveness was surveyed among 61 participants before and immediately after the workshop, and at 1-week and 1-month later. The analysis compared initial scores obtained before the workshop with subsequent responses. Where a significant difference was observed among three-group or more in the Friedman test, the Wilcoxon signed-rank test was used for two-group comparisons across the time periods. The significance level was set at P<0.05. Results: Data of 54 participants were analyzed. The knowledge based on Bloom’s taxonomy was increased as the number of correct responses increased significantly after the workshop (P<0.001). Cognitive domain was significantly increased after 1-week and 1-month (P<0.001). Affective and psychomotor performances were also increased compared with prior. Participants increased vocabulary related to radiation and developed confidence in radiation disaster recovery measures. Conclusion: Each sub-item of the Bloom’s attainment (goal, cognitive, affective, psychomotor) has almost been reached and the effect was maintained even after 1-month. By learning concrete words, they could explain accurately. Participants improved their confidence after receiving the training to respond and clarify the radiation anxieties to the community people.

Acetylated tubulin and risk of nodal metastases in squamous cell carcinoma of the head and neck (SCCHN).

2012 ◽  
Vol 30 (15_suppl) ◽  
pp. 5560-5560
Author(s):  
Nabil F. Saba ◽  
Kelly R. Magliocca ◽  
Sungjin Kim ◽  
Susan Muller ◽  
Zhengjia Chen ◽  
...  
Keyword(s):  
Smoking Status ◽  
Tumor Location ◽  
Nodal Metastasis ◽  
Rank Test ◽  
Nodal Metastases ◽  
Acetylated Tubulin ◽  
Response To Chemotherapy ◽  
Significant Difference ◽  
The Difference ◽  
Tissue Specimens

5560 Background: We previously established that AT expression predicts for response to chemotherapy in SCCHN (Saba et al, AACR 2010 meeting abstr 3744). We wanted to further examine the relation of AT expression and nodal metastases in SCCHN. Methods: We assessed AT expression in archival tissue specimens from primary SCCHN cases with (50 cases) and without (53 cases) lymph node metastases (NM) using standard immunohistochemistry (IHC). Clinical characteristics of patients were retrieved from the department of pathology under the guidelines of the institutional review board (IRB). IHC staining for AT was scored based on intensity and percentage of tumor cells stained: 0 = no staining, 1+ = weak, 2+ = moderate, 3+ = moderate to high, 4+ = high and a weighted index (WI) was calculated as percent stain x stain intensity. Wilcoxon two-sample test and Kruskal-Wallis test were used to estimate the relationships of the WI with nodal metastasis, node status, primary tumor location, grade, and stage. Log-rank test was used to examine the difference in OS and DFS among four groups based on quartiles of the WI. A Cox proportional hazard model was employed to estimate the adjusted effect of WI on OS and DFS. Results: A higher AT expression was associated with nodal metastasis (p=0.0155) and higher stage (p=0.0311). A lower AT expression was associated with oral cavity primary (p=0.0107). After adjusting for age, gender, race, and smoking status, a lower AT expression was significantly associated with better DFS in the subset of patients with NM by multivariate analysis (HR=1.008; 95% CI=1.002- 1.014; p=0.0123). Among patients with no NM there was a marginally significant difference in OS among four different groups based on quartiles of AT expression (p=0.0765). Conclusions: High AT expression is associated with nodal metastases in SCCHN and may be a marker of poor prognosis in patients with node positive disease. The value of AT as a prognostic marker in SCCHN needs to be better defined. This work is supported by a SPORE CDP Grant P50 CA128613-03 to NFS.

Association between intratumoral HER2 heterogeneity (IHH) and trastuzumab (T-mab) efficacy in HER2 positive–gastric cancer (GC).

2015 ◽  
Vol 33 (3_suppl) ◽  
pp. 92-92
Author(s):  
Takeru Wakatsuki ◽  
Noriko Yamamoto ◽  
Keisho Chin ◽  
Mariko Ogura ◽  
Eiji Shinozaki ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Statistical Tests ◽  
Progression Free Survival ◽  
Clinical Impact ◽  
Heterogeneous Group ◽  
Rank Test ◽  
Her2 Positive ◽  
Kaplan Meier ◽  
Significant Difference ◽  
The Difference

92 Background: ToGA study showed superiority of adding T-mab to standard chemotherapy and a positive correlation between HER2 expression levels and the T-mab efficacy. In gastric cancer IHH is frequently recognized but its clinical impact on T-mab efficacy is unclear. Methods: Patients who were treated with T-mab and had surgical specimens available for IHC test were retrospectively examined. When all tumor cells overexpressed HER2 protein by IHC, the tumor was defined as non-HER2-heterogeneous. The others were defined as HER2-heterogeneous. Progression-free survival (PFS) and overall survival (OS) were estimated using by Kaplan-Meier methods and compared by the log-rank test. The level of significance was set to p<0.05 and all statistical tests were two-sided. Results: 23 patients were enrolled. Their median age was 68 years and 83% were male. PS 0, GEJ cancer, intestinal type histology, visceral metastasis (lung or liver), and previous chemotherapy were found in 57%, 35%, 83%, 57%, and 57% of them, respectively. After a median follow-up of 11.3 months, the median OS, PFS, and overall response rate were 14.4 months, 10.8 months, and 62.5%, respectively. All tumors were IHC3+, and 13 were non-HER2-heterogeneous and 10 were HER2-heterogeneous. There was no significant difference in clinicopathological features between the two groups. Median PFS in non-HER2-heterogeneous group (21.9 months) was significantly longer than that in HER2-heterogeneous group (8.6 months), (HR: 0.24 [0.06-0.91], P=0.024). Median OS in non-HER2-heterogeneous group was not reached while that in HER2-heterogeneous group was 12.9 months (HR: 0.29 [0.06-1.42], P=0.102). A higher rate of response to T-mab was seen in non-HER2-heterogeneous group than in HER2-heterogeneous group, though the difference was not statistically significant (75% vs. 50%, p=0.608). Conclusions: IHH might have robust clinical impact on T-mab efficacy for HER2 positive GC. These findings should be validated by independent large cohorts and further molecular correlative analyses are warranted.

scholarly journals Moringa oleifera Intake during Pregnancy and Breastfeeding toward Docosahexaenoic Acid and Arachidonic Acid Levels in Breast Milk

2020 ◽  
Vol 8 (B) ◽  
pp. 757-761
Author(s):  
Karmila Sari ◽  
Saifuddin Sirajuddin ◽  
Martira Maddepungeng ◽  
Veni Hadju ◽  
Ariyanti Saleh ◽  
...  
Keyword(s):  
Arachidonic Acid ◽  
Breast Milk ◽  
Docosahexaenoic Acid ◽  
Moringa Oleifera ◽  
Food Supplement ◽  
Significance Level ◽  
Significant Difference ◽  
Low Education ◽  
The Difference ◽  
Iron Folic Acid

BACKGROUND: Moringa oleifera is a nutritional food supplement that can save lives, particularly in countries with malnourished community. Such supplement can also be provided to breastfeeding mothers so that they can produce more breast milk. AIM: This study investigated the effect of M. oleifera on pregnant and breastfeeding mothers on their breast milk’s docosahexaenoic acid (DHA) and arachidonic acid (AA) concentration. METHODS: This was a longitudinal study which was the continuity from the previous experimental study. The research sample was 64 breastfeeding mothers given Moringa leaves powder (MLP), Moringa leaves extract (MLE), or iron-folic acid (IFA). The data were analyzed using Kruskal–Wallis test with the significance level of 95% aiming to assess the difference between the breast milk’s DHA and AA level on MLP, MLE, and IFA groups. RESULTS: This research indicated that most mothers had low education level (71.9 %) and did not work (89.1%). There was no significant difference between the DHA level (p = 0.215) and AA (p = 0.914) of the breast milk among the MLP, MLE, and IFA groups. CONCLUSION: The intervention might contribute a little effect on DHA and AA level in the breast milk.

scholarly journals Measurement of loosening torque of prosthetic components in Morse taper connection implants

2014 ◽  
Vol 2 (4) ◽  
pp. 335
Author(s):  
Dimas João Rodrigues Neto ◽  
Giordano Maciel Silva ◽  
Daiane Cerutti-Kopplin ◽  
Jefferson Ricardo Pereira ◽  
Keila Cristina Raush ◽  
...  
Keyword(s):  
Mechanical Resistance ◽  
Significance Level ◽  
Significant Difference ◽  
Steel Base ◽  
Different Types ◽  
Minute Interval ◽  
The Difference ◽  
Student’S T ◽  
Torque Values ◽  
Student’S T Test

AIM: The aim of this study was to verify two different types of interfaces in Morse taper connection implants, relating the mechanical resistance to a loosening torque that is required to separate or move the prosthetic abutment. MATERIAL AND METHODS: Ten Morse taper connection implants and their respective abutments were divided into two groups (n = 5), DH (double hexagon) interface and OI (octagonal implant) interface. A standard insertion of implants was performed in a stainless steel base, where each abutment received a sequence of two consecutive tightening torques at a 10-minute interval, followed by a loosening torque, which was measured using a digital torque gauge. The Student’s t-test with a 5% significance level was used for data analysis. RESULTS: The results showed a statistically significant difference in the loosening torque values compared with DH torque values (p < 0.05). However, the difference between tightening and loosening torque values was not statistically significant in the OI group (p = 0.465). CONCLUSION: The study concluded that there was a difference in the torque required to loosen the abutment screws between the DH group and the OI group, with the latter showing better results.

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