Precipitation of Sugammadex With Nicardipine And Labetalol

Mapping Intimacies ◽

10.21203/rs.3.rs-1209442/v1 ◽

2022 ◽

Author(s):

Jiwon Han ◽

Ah-Young Oh ◽

Bo Young Kim

Keyword(s):

Experimental Study ◽

Clinical Data ◽

Light Microscope ◽

Precipitation Reaction ◽

Before And After ◽

Formed Precipitate

Abstract BackgroundThere is a paucity of clinical data about whether sugammadex forms precipitates with other medications. This laboratory experimental study was performed to determine the drugs that produce precipitate with sugammadex. MethodsSamples of 1 mL of sugammadex were prepared in transparent cylinders, to which 1 mL of test drugs (rocuronium, neostigmine, glycopyrrolate, atropine, nitroglycerin, dobutamine, dopamine, epinephrine, vasopressin, norepinephrine, phenylephrine, ephedrine, esmolol, nicardipine, labetalol) was then added. The precipitation reaction was observed by eyes and light microscope. The pH of each drugs before and after mixing with sugammadex was measured. ResultsWhite crystals were formed when sugammadex mixed with nicardipine or labetalol. ConclusionsSugammadex formed precipitate when mixed with nicardipine or labetalol. Sufficient fluid flushing is required between injections of each drug to prevent these reactions.

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Experimental Study on Uniaxial Compression Behavior of Fissured Loess Before and After Vibration

International Journal of Geomechanics ◽

10.1061/(asce)gm.1943-5622.0002259 ◽

2022 ◽

Vol 22 (2) ◽

Author(s):

Jian Xu ◽

Liyang Zhou ◽

Yanfeng Li ◽

Jiulong Ding ◽

Songhe Wang ◽

...

Keyword(s):

Experimental Study ◽

Uniaxial Compression ◽

Compression Behavior ◽

Before And After

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Promotion of Early and Exclusive Breastfeeding in Neonatal Care Units in Rural Rwanda: a Quasi-experimental Study

10.21203/rs.3.rs-119415/v1 ◽

2020 ◽

Author(s):

Saidath Gato ◽

Francois Biziyaremye ◽

Catherine M. Kirk ◽

Chiquita Palha De Sousa ◽

Alain Mukuralinda ◽

...

Keyword(s):

Experimental Study ◽

Exclusive Breastfeeding ◽

Child Survival ◽

Neonatal Care ◽

Post Intervention ◽

Factors Associated ◽

Before And After ◽

Quasi Experimental ◽

Evidenced Based ◽

Additional Support

Abstract Background: Early initiation of breastfeeding after birth and ongoing exclusive breastfeeding for the first 6 months improves child survival, nutrition and health outcomes. However, only 42% of newborns worldwide are breastfed within the first hour of life. Small and sick newborns are at greater risk of not receiving breastmilk and often require additional support for feeding. This study compares breastfeeding practices in Rwandan neonatal care units (NCUs) before and after the implementation of a package of interventions aimed to improve breastfeeding, aligned with the Baby Friendly Hospital Initiative for small and sick newborns.Methods: A pre-post quasi experimental study was conducted at two District hospital NCUs in rural Rwanda from October 2017–December 2017 (pre-intervention) and September 2018–March 2019 (post-intervention). Only newborns admitted before their second day of life (DOL) were included. Data was extracted from patient charts for clinical and demographic characteristics, feeding throughout admission, and patient outcomes. Bivariate analyses were conducted using Fisher’s exact and Wilcoxon rank sum tests. Logistic regression was used to evaluate factors associated with exclusive breastfeeding at discharge following a backwards stepwise procedure.Results: Pre-intervention, 255 newborns were admitted in the NCUs and 793 were admitted in the post-intervention period. The percentage of infants who were exclusively breastfed on their day of birth, or day-of-life zero (DOL0) increased from 5.4% to 35.9% (p<0.001). For newborns discharged alive, the proportion exclusively breastfeeding increased from 69.6% to 87.0% (p<0.001). The mortality rate for all admitted newborns decreased from 16.1% to 10.5% (p<0.019). Factors associated with greater odds of exclusive breastfeeding at discharge included post-intervention time point (Odds Ratio (OR): 4.91, 95% Confidence Interval (CI) 1.99-12.11, p<0.001), and admission for infection (OR 2.99, 95%CI 1.13-7.93, p=0.027). Home deliveries (OR 0.15, 95%CI 0.05-0.47, p=0.001), preterm delivery (OR 0.36, 95%CI 0.15-0.87, p=0.0260 and delayed first breastmilk feed (OR=0.04 for DOL3 vs. DOL0, 95%CI 0.01, 0.35, p=0.004) reduced odds of exclusive breastfeeding at discharge. Conclusion: Expansion and adoption of evidenced-based guidelines, using innovative approaches, aimed at the unique needs of small and sick newborns should be expanded and adapted in similar settings to improve outcomes for these infants.

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Comparative Analysis of Capabilities of Different Types of Cone-Beam Tomography in an Experimental Study of Root Canals of Teeth Filled with High-Density Materials (part 2)

Radiology - Practice ◽

10.52560/2713-0118-2021-2-51-61 ◽

2021 ◽

pp. 51-61

Author(s):

A. Yu. Vasil'ev ◽

V. V. Petrovskaya ◽

E. A. Nichipor ◽

V. G. Alpatova ◽

N. N. Potrakhov ◽

...

Keyword(s):

Computed Tomography ◽

Experimental Study ◽

Cone Beam Computed Tomography ◽

Comparative Assessment ◽

High Density ◽

Cone Beam ◽

Root Canals ◽

Different Types ◽

Before And After ◽

Cone Beam Tomography

During the course of this experimental study tomograms of extracted teeth were analyzed before and after filling the root canals with an endodontic material and fragments of broken metal instruments for root canal treatment. During the first stage of the experiment, untreated extracted teeth were scanned using conebeam computed tomography and microfocus cone-beam computed tomography. A comparative assessment of capabilities of the two methods of cone-beam computed tomography based on examination of untreated root canals was carried out. The second part of the study is dedicated to visualization of root canals that contain foreign high-density materials.

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Immunization competence retention in medical students: a comparation between conventional lectures and lectures with simulations method

Paediatrica Indonesiana ◽

10.14238/pi55.6.2015.339-44 ◽

2016 ◽

Vol 55 (6) ◽

pp. 339 ◽

Cited By ~ 1

Author(s):

Hartono Gunadi ◽

Rini Sekartini ◽

Retno Asti Werdhani ◽

Ardi Findyartini ◽

Muhammad Arvianda Kevin Kurnia

Keyword(s):

Experimental Study ◽

Medical Students ◽

Medical School ◽

Intervention Group ◽

Control Group ◽

Vaccine Preventable Diseases ◽

Before And After ◽

Quasi Experimental

Background Immunization is recognized as one of the strategiesto reduce vaccine preventable diseases. Competency related toimmunization are consequently important for medical students andthe medical school needs to assure the competence acquisition.Objective To assess competence related to immunization andits retention following lectures with simulations compared tolectures only.Methods A quasi-experimental study was conducted to the 5th yearstudents of University of Indonesia Medical School during the ChildAdolescent Health Module in 2012-2013. The intervention grouphad lectures with simulations and the control group had lecturesonly. Immunization knowledge was assessed with a 30 multiplechoice question (MCA) items performed before and after themodule. Competence retention was assessed by MCQ (knowledge)and OSCE (skills) 2-6 months afterwards.Results Sixty eight subjects for each group with similarcharacteristics were analyzed. There was significant differenceafter module MCQ score between two groups. Competenceretention in 2-6 months after module completion was betterin intervention group, both for the knowledge (median MCQscore of 70.00 (range 37-93) vs. mean score of 58.01 (SD 12.22),respectively; P<0.001) and skill (OSCE mean scores of 75.21 (SD10.74) vs. 62.62 (SD 11.89), respectively; P < 0.001). Proportionof subjects in the intervention group who passed both the MCQand OSCE were also significantly greater.Conclusion Lectures with simulations are proved to bemore effective in improving medical students’ immunizationcompetence as well as its retention compared to lectures onlyapproach.

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Efektivitas Tindakan Skeling terhadap Perawatan Gingivitis di Rumah Sakit Gigi dan Mulut Universitas Sam Ratulangi Manado

e-GIGI ◽

10.35790/eg.7.2.2019.23928 ◽

2019 ◽

Vol 7 (2) ◽

Author(s):

Febri Korompot ◽

Krista V. Siagian ◽

Damajanty H. C. Pangemanan ◽

Johanna Khoman

Keyword(s):

Experimental Study ◽

Inflammatory Response ◽

Periodontal Disease ◽

Sampling Technique ◽

P Value ◽

Test Design ◽

Gingival Index ◽

Paired Sample ◽

Before And After ◽

Post Test

Abstract: The most common periodontal disease is gingivitis which is caused by biofilm accumulation on plaque around the gingival margin and inflammatory response to bacteria. Scaling is used to eliminate bacterial and calculus deposits that cause gingivitis. This study was aimed to determine the effectiveness of scaling in gingivitis treatment. This was a pre-experimental study with one group pre and post test design. Samples were obtained by using total sampling technique. There were 30 patients aged 17-45 years that had scaling performed on them at RSGM in 2019. Gingivitis was observed before and after scaling using the modified gingival index (MGI). The results showed that before scaling, there were mild gingivitis 23.30%, moderate gingivitis 70%, and severe gingivitis 6.70%. Two days after scaling, mild gingivitis and moderate gingivitis were observed 50% each. The paired sample t-test showed a p-value of 0.000. In conclusion, scaling is effective in gingivitis treatment based on the assessment using the modified gingival index.Keywords: gingivitis, scaling, modified gingival index Abstrak: Penyakit periodontal yang paling sering dijumpai yakni gingivitis (peradangan gingiva). Gingivitis disebabkan oleh akumulasi biofilm pada plak di sekitar margin gingiva dan respon peradangan terhadap bakteri. Tindakan untuk menghilangkan deposit bakteri dan kalkulus yang menyebabkan gingivitis salah satunya ialah tindakan skeling. Tujuan penelitian ini untuk mengetahui efektivitas tindakan skeling terhadap perawatan gingivitis. Jenis penelitian ialah pra eksperimental dengan one grup pre and post test design. Pengambilan sampel menggunakan teknik total sampling terhadap pasien yang berusia 17-45 tahun yang dilakukan tindakan skeling di RSGM pada tahun 2019 berjumlah 30 orang. Penelitian ini dilakukan dengan melihat gingivitis sebelum skeling dan setelah skeling melalui pengukuran keparahan gingiva menggunakan modified gingival index (MGI). Hasil penelitian menunjukkan bahwa sebelum skeling gingivitis ringan 23,30%, gingivitis sedang 70%, gingivitis berat 6,70%. Dua hari pasca skeling didapatkan gingivitis ringan dan gingivitis sedang sama besar yaitu masing-masing 50%. Hasil uji t berpasangan menunjukkan nilai p=0,000. Simpulan penelitian ialah tindakan skeling efektif terhadap perawatan gingivitis berdasarkan penilaian modified gingival index.Kata kunci: gingivitis, skeling, modified gingival index

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Subcuticular catgut versus polyglactin 910 in scar formation in sheep

Veterinární Medicína ◽

10.17221/5753-vetmed ◽

2012 ◽

Vol 48 (No. 3) ◽

pp. 79-82

Author(s):

Ž ◽

F. Rudman ◽

E. Amić ◽

Z. Stanec ◽

I. Stipančić ◽

...

Keyword(s):

Experimental Study ◽

Foreign Body ◽

Microscopic Examination ◽

Light Microscope ◽

Scar Formation ◽

Plastic Surgeon ◽

Foreign Body Granuloma ◽

Surrounding Tissue ◽

Polyglactin 910 ◽

Double Blind

The aim of this double blind prospective experimental study was to compare the influence of polyglactin 910 (Vicryl, Ethycon ) and plain catgut (Soficat-Plein,Braun) as subcuticular tissue sutures on wound healing and scar formation in sheep. Scar excision together with the surrounding tissue was made three months later. Scars were compared visually, photographed and examined under a light microscope. All scars were cosmetically acceptable, linearly hardly visible, aplanated and less than 1 mm in width with no difference between the parts in which plain catgut or polyglactin 910 were used. All photographs were examined by a plastic surgeon as well as by a dermatologist and they confirmed that all scars were cosmetically acceptable, hardly visible, aplanated and less than 1 mm in width. During the light microscopic examination done by the dermatologist foreign body granulomas were found in two scars where the subcuticular plain catgut was used. Concerning the plain catgut as an animal and foreign body granuloma inductor, the use of polyglactin 910 seems to be beter.

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Depressão e ideação suicida na adolescência: implementação e avaliação de um programa de intervenção

Enfermería Global ◽

10.6018/eglobal.402951 ◽

2020 ◽

Vol 19 (3) ◽

pp. 1-35

Author(s):

Ana Paula Amaral ◽

Josiane Uchoa Sampaio ◽

Fátima Regina Ney Matos ◽

Margarida Tenente Santos Pocinho ◽

Rafael Fernandes de Mesquita ◽

...

Keyword(s):

Experimental Study ◽

Depressive Symptoms ◽

Suicidal Ideation ◽

Suicide Prevention ◽

Prevention Program ◽

Intervention Program ◽

Educational Institution ◽

Assessment Instruments ◽

Before And After ◽

Quasi Experimental

Objetivo: Desarrollar, implementar y evaluar un programa de prevención del suicidio dirigido a adolescentes.Materiales y Métodos: Estudio cuasi experimental, del tipo antes y después, con adolescentes de una institución educativa en São Luís, Maranhão, Brasil. El estudio siguió las etapas de desarrollo, implementación y evaluación de un programa de intervención para la prevención del suicidio. Se administraron tres instrumentos de evaluación antes y después de la intervención: la escala de ideación suicida de Beck; el Inventario de Depresión de Beck y la Escala de Desesperanza de Beck.Resultados: Antes de la intervención, participaron 102 adolescentes, 30 (29.4%) tenían ideación suicida y síntomas depresivos. Después de la intervención, los instrumentos se aplicaron a los 30 adolescentes seleccionados, 12 (40.0%) continuaron con la ideación. Antes de la intervención, el Inventario de depresión promedio fue de 23.83 y luego de 7.17 (p <0.0001). En cuanto a la desesperanza, el promedio obtenido antes fue 7.23 y luego 2.17 (p <0.0001); Con respecto a la ideación suicida, el promedio obtenido antes fue de 10.50 y luego de 2.57 (p <0.0001).Conclusión: Hubo una disminución en los síntomas depresivos, la desesperanza y la ideación suicida después de la implementación del elaborado programa de intervención. Objective: To develop, implement and evaluate a suicide prevention program aimed at adolescents.Material and Methods: A quasi-experimental study, before and after, with adolescents from an educational institution in São Luís, Maranhão, Brazil. The study followed the stages of development, implementation and evaluation of a suicide prevention intervention program. Three assessment instruments were administered before and after the intervention: Beck's Suicidal Ideation Scale; Beck's Depression Inventory and Beck's Hopelessness Scale. Results: Before the intervention, 102 adolescents participated, 30 (29.4%) had suicidal ideation and depressive symptoms. After the intervention the instruments were applied to the 30 selected adolescents, 12 (40.0%) continued with ideation. Prior to intervention, the average Depression Inventory was 23.83 and then 7.17 (p <0.0001). As for hopelessness, the average obtained before was 7.23 and then 2.17 (p <0.0001); Regarding suicidal ideation, the average obtained before was 10.50 and then 2.57 (p <0.0001). Conclusion: There was a decrease in depressive symptoms, hopelessness and suicidal ideation after the implementation of the elaborated intervention program.

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Telephone interventions for adherence to colpocytological examination

Revista Latino-Americana de Enfermagem ◽

10.1590/1518-8345.1683.2844 ◽

2017 ◽

Vol 25 (0) ◽

Author(s):

Thais Marques Lima ◽

◽

Ana Izabel Oliveira Nicolau ◽

Francisco Herlânio Costa Carvalho ◽

Camila Teixeira Moreira Vasconcelos ◽

...

Keyword(s):

Cervical Cancer ◽

Experimental Study ◽

Educational Intervention ◽

Educational Interventions ◽

Inclusion Criteria ◽

Examination Method ◽

Before And After ◽

Quasi Experimental ◽

Behavioral Group ◽

Health Education And Promotion

ABSTRACT Objective: to test the effects of behavioral and educational intervention by telephone on adherence of women with inappropriate periodicity to colpocytological examination. Method: quasi-experimental study with a sample of 524 women, selected with the following inclusion criteria: be aged between 25 and 64 years, have initiated sexual activity, have inappropriate periodicity of examination and have mobile or landline phone. The women were divided into two groups for application of behavioral and educational intervention by telephone. It was used an intervention script according to the principles of Motivational Interviewing. Results: on comparing the results before and after the behavioral and educational interventions, it was found that there was a statistically significant change (p = 0.0283) with increase of knowledge of women who participated in the educational intervention. There was no change in the attitude of women of any of the groups and there was an increase of adherence to colpocytological examination in both groups (p < 0.0001), with greater adherence of women participating in the behavioral group (66.8%). Conclusion: the behavioral and educational interventions by phone were effective in the adherence of women to colpocytological examination, representing important strategies for permanent health education and promotion of care for the prevention of cervical cancer.

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Athletes’ Perceptions of a Coach Who Faked Confidence

Journal of Coaching Education ◽

10.1123/jce.4.1.83 ◽

2011 ◽

Vol 4 (1) ◽

pp. 83-98

Author(s):

Barrett Wilson ◽

Sandra E. Short ◽

Martin W. Short

Keyword(s):

Experimental Study ◽

North Dakota ◽

Qualitative Data ◽

Three Dimensions ◽

Neutral Zone ◽

Presentation Style ◽

Paired Sample ◽

Hockey Players ◽

Before And After

This experimental study examined differences in athletes’ perceptions of a coach who faked confidence. The participants (n = 29) were elite hockey players from the Dallas Stars organization and North Dakota men’s hockey program. They completed a questionnaire after watching a video of a coach draw up a neutral zone forecheck. Participants then read a short scenario that explained that the coach was faking his confidence regarding his knowledge about the strategy he presented. The athletes then completed the same set of questions again. Paired-sample t-tests compared the athletes’ ratings before and after they were told that the coach was faking his confidence. The questions were about coach’s confidence (in general), the coach’s confidence in the strategy he presented, and the athlete’s perception that the coach would be confident in his ability to explain a different strategy. All values significantly decreased (p = .00) after the participants were told that the coach was faking confidence. From the qualitative data, three dimensions (i.e., confidence, knowledge, and presentation style) were prominent. These qualitative results provide insight as to why the athletes’ perceptions of the coach changed from positive (e.g., athletes’ perceived the coach was confident) to negative (e.g., athletes’ perceived that the coach was not confident) after finding out the coach was faking his confidence. Coaches should be aware that they can effectively fake confidence. However, if a coach were to fake it and “get caught,” then they should know that the athletes’ perceptions of them may become negative quickly.

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