scholarly journals Alcohol Quantity and Type on Risk of Gouty tophi

Author(s):  
Lin Han ◽  
Renze Li ◽  
Wei Ren ◽  
Jingyuan Pang ◽  
Jian Sun ◽  
...  

Abstract Objective: The aim of this study was to explore the impact of drinking alcohol on tophi and its surrounding inflammation in the joints by ultrasound. Methods: We conducted a cross-sectional study on 356 gout patients and collected their information of drinking history, clinical biochemical parameters and ultrasound results. Multiple regression analyses including several variables and potential confounders were then performed. Results: Relative to no drinking, more alcohol intake (>200 g/week), longer drinking time (>20 years) and higher frequency of drinking (>2 times/week) had significant positive effects on the size of tophus after controlling for potential confounders (P=0.024; P=0.002; P=0.040). Further subgroup analysis of different ages illustrated that more alcohol consumption had positive effects on the size of tophi only in the younger gout patients (≤50 years old), rather than in older ones (>50 years old). However, alcohol consumption had no significant association with the formation and number of tophus, and the associations between type of drinking and tophi was not observed in the current study. Moreover, except for tophi, there was no relationship between alcohol consumption and other ultrasound signs including double-contour sign (DCS), bone erosion, effusion and synovial hypertrophy.Conclusion: Alcohol consumption is closely associated with ultrasound-detected tophi in gout patients. More alcohol intake, longer drinking time and higher frequency of drinking are crucial factors that positively affect the size of tophus, especially in younger gout patients. However, significant association between type of alcohol and tophi was not observed in the current study.

2021 ◽  
Author(s):  
Eyayu Kasseye Bayu ◽  
Getaneh Bizuayehu Demeke

Abstract Background: The aims of this study was to assess knowledge and attitudes of reproductive women (15-49) towards alcohol consumption during pregnancy in West Gojjam of Amhara region.Methods: Community based cross sectional study design was employed. The structured questionnaires were used to assess the knowledge and attitude of alcohol consumption among reproductive women during pregnancy. The sample size was calculated by using a single population proportion formula. Accordingly, the calculated sample size was 380 after adding 10% for non-response rate.Descriptive statistics, binary and multivariable logistic regressions was employed. Adjusted Odds Ratios together with corresponding 95% confidence intervals was used to interpret the findings.Results: The majority of women 308(82.4%) were know the problems of drinking alcohol during pregnancy from 374 total study participants. Knowledge of women with regard to problems of drinking alcohol during pregnancy were associated literate women (AOR=0.416; 95%CI=0.207-0.836) and risk of alcohol consumption during pregnancy low (AOR=9.468; 95% CI=3.466-25.868).Addationally,attitude of women for consumption of alcohol have significant effect on health associated with occupation status a housewife ((AOR=4.620; 95% CI= (1.255-17.012), had own business(AOR=17.344;95% CI=1.821165.148), alcohol consumption for 3-4 days a week(AOR=11.278;95%CI =1.231-103.287),relative encourage diriking alcohol (AOR=0.309;95%=0.110-0.868), Women who had previously health problems (AOR=0.330;95% CI=0.152-0.717), women who perceive the risk of alcohol consumption have beneficial effect on health is medium(AOR=7.112; 95% CI =3.108-16.270), attitudes of women towards alcohol consumption have beneficial effect on health is high (AOR= 4.902;95% CI =1.474-16.297),women who agree on the consumption of alcohol during pregnancy is valuable(AOR=0.082;95% CI =0.023-0.287).Conclusion: The study revealed that, the knowledge of women on the health effect of alcohol consumption during pregnancy high. Their attitude also towards alcohol consumption is low and medium. Interventions focused on creating awareness about the harmful effects of alcohol consumption on pregnancy should implemented.


PLoS ONE ◽  
2021 ◽  
Vol 16 (5) ◽  
pp. e0251525
Author(s):  
Lis Campos Ferreira ◽  
Rívia Siqueira Amorim ◽  
Fellipe Matos Melo Campos ◽  
Rosana Cipolotti

Introduction: SARS-Cov-2 virus pandemic causes serious emotional consequences. It has occurred widespread medical courses suspension, and graduations were anticipated. Field hospitals, set up to treat patients with mild to moderate COVID-19, were the main workplaces of newly graduated doctors. Objective: To assess the impact of SARS-Cov-2/COVID-19 pandemic on mental health of medical interns and newly graduated doctors. Method: This is a cross-sectional study performed using a digital platform. Links to forms were sent in two moments: moment 1 (M1), at the beginning of the pandemic, in the first half of April/2020 and moment 2 (M2), after six months of pandemic, in the second half of September/2020. All students from the medical internship and all doctors graduated since 2018 from the three medical schools in Sergipe-NE-Brazil were invited. Results: 335 forms were answered in April and 148 in September. In M1 88.9% considered themselves exposed to excess of information about COVID-19, which was associated with anxiety symptoms (p = 0.04). Long family physical distance was also associated with these symptoms, as increased appetite (p = 0.01), feeling shortness of breath (p = 0.003) and sweating (p = 0.007). Fear of acquire COVID-19 was reported as intense by almost half of participants, and of transmitting by 85.7% in M1. In M2 41.2% reported the death of friends or relatives. Psychiatric illness was described by 38.5% and psychotropic drugs use by 30.1% in M1, especially those who lived alone (p = 0.03) and the single ones (p = 0.01). Alcohol intake was reported by 54.3%, and among doctors graduated in 2020 it increased from 50% in M1 to 85% in M2 (p = 0.04). Conclusion: The pandemic had a negative impact on the mental health of medical students and newly graduated doctors. Exposure to excessive COVID-19 information and family physical distance were associated to anxiety symptoms. Among doctors graduated in 2020, alcohol intake increased during pandemic evolution.


2020 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Christelle Bou-Mitri ◽  
Marilyn Abdessater ◽  
Hani Zgheib ◽  
Zeina Akiki

Purpose The purpose of this paper is to assess the impact of the packaging design on consumers’ perception of the food quality, safety, healthiness and preference to buy. Design/methodology/approach A cross-sectional study recruited a convenience sample of 547 Lebanese adults with a median age of 30 years old and 54% being females, between November and December 2016, using an interviewer-based questionnaire. Findings As identified by the participants, packaging should “protect the food” (54.9%) and be safe (52%). Most participants especially those who reported that protecting the food is the most important packaging functionality tended to select the vacuum package [OR (95% CI) = 2.19 (1.32; 3.66); p = 0.002] for having the highest quality, being the healthiest and the more frequently bought (24.3, 30.2 and 29.1% respectively). Regarding the juice, most of the participants thought that the glass bottles have the highest quality, were the safest, the healthiest and the most frequently bought (64.9, 37.4, 68.4 and 52.9%, respectively). Those who reported that safety is the most important characteristic for food packaging, have selected transparent as the most attractive color to use [OR (95% CI) = 2.10 (1.25; 3.55); p-value = 0.005]. Among the consumers, 87% considered that nutrition and health claims were among the most important informative cues. Around 73.1% (n = 399) were willing to pay more for a better packaging with 59.4% willing to pay 3% more. Originality/value This market research identifies the packaging characteristics and features which have positive effects on consumer attitudes. Therefore, it will help manufacturers track consumers’ trends and interests, and accordingly impact their business decisions in responding adequately in their package design. The social behavior will increase the product sale and its market success leading to direct economic implications.


Author(s):  
Mehak Agarwal ◽  
Prithvi Ravi ◽  
Chitra A. Ramesh ◽  
Judson J. Neslin

Background: We conducted this survey to determine the impact of covid-19 on the mental health of people during the pandemic and period of lockdown. We evaluated certain factors such as sleep changes, anxiety, mood swings, irritability, inability to concentrate, smoking and alcohol consumption changes.Methods: A cross-sectional study was conducted. We conducted an online questionnaire and circulated it via various social media platforms to record and evaluate responses of people. SPSS 16 version software and Microsoft excel sheet were used.Results: According to the results, people suffered from negative symptoms such as stress, fear, changes in smoking habits, changes in alcohol consumption, mood swings, inability to concentrate, sleep disturbances. Most people also started new coping mechanisms to help their psychological symptoms.Conclusions: An association between mental health and the outbreak of a pandemic was noticed. People experiencing these should get help and practice relaxation methods to prevent progression of their symptoms.


2020 ◽  
Author(s):  
So Young Lee ◽  
Jinhwa Lee ◽  
Min Kwon

Abstract Background: Presenteeism refers to the practice of going to work despite poor health, resulting in subpar performance. The problems caused by smoking and drinking alcohol while on company premises have received limited attention despite their health hazards, which are linked to sick leave, occupational injuries, and reduced productivity. This study aimed to investigate the effects of smoking and alcohol drinking on presenteeism. Methods: The study participants were 60,051 wage workers from the database of the second and third Korean Working Conditions Surveys (KWCS) in 2010 and 2011 , respectively. A total of 41,672 workers aged 19 and over who had worked for at least one hour in the previous week answered the survey questions. Chi-squared tests and multiple logistic regression analyses were conducted using SPSS 18.0 to determine the impacts of smoking and drinking alcohol on presenteeism. Results: Of the 41,672 Korean workers, 8565 (20.6%) had experienced presenteeism in the past 12 months. Presenteeism was higher among women; the elderly; people with low educational status; people with low income; people with 5-11 days absenteeism; people with more working time; people with health problems; heavy smokers; and high-risk alcohol drinkers than other participants. Based on the results of multiple regression analysis, heavy smoking (AOR = 2.10, 95% CI [1.56, 2.82]) and high-risk drinking of alcohol (AOR = 1.20, 95% CI [1.10, 1.31]) were significantly related to presenteeism among workers.Conclusions: Smoking and alcohol drinking are associated with and potentially influence presenteeism; therefore, interventions for employees, and for the general public, may improve workplace productivity and reduce accidents. Companies that encourage employees to receive treatments for reduction of smoking or alcohol consumption may benefit from greater productivity. Hence, we should consider the impact of smoking and alcohol in the workplace and build appropriate strategies and implementation programs to help reduce heavy smoking and high-risk alcohol drinking behaviors.


2021 ◽  
Vol 9 ◽  
Author(s):  
Zi-gui Chen ◽  
Ling-jun Kong ◽  
Min Wang ◽  
Hang-kai Liu ◽  
Da-kai Xiao ◽  
...  

Rational planning and optimization of urban spatial form to achieve the goal of energy efficient utilization and carbon emission reduction is one of the important ways to improve energy efficiency. We deconstruct urban spatial form into centrality, aggregation and complexity, and analyze net effect and its heterogeneity of urban spatial form on energy efficiency with OLS, quantile regression model as well as grouped regression model. The results show that the effects of urban spatial centrality and complexity on energy efficiency are nonlinear. For the vast majority of cities, strengthening urban spatial centrality will significantly improve energy efficiency, but the growth rate will gradually decrease. The impact effect of urban complexity on energy efficiency has the characteristics of U-shaped trend with an inflection point value of 0.429. And for the three-quarters of urban samples, enhancing urban spatial complexity will reduce energy efficiency. The positive effect of urban spatial aggregation on energy efficiency is only significant in cities with high quantile for energy efficiency. In terms of urban heterogeneity, the positive effects of spatial centrality and aggregation on energy efficiency are more obvious in megacities with a permanent population of more than 5 million, and the negative effect of spatial complexity on energy efficiency is more obvious in small and medium-sized cities. Whether it is promotion or inhibition, the urban samples with high energy efficiency are more affected by the change of urban spatial form. Optimizing the urban spatial form is one of the important ways to improve the energy efficiency, and the policy setting should give full consideration to the urban heterogeneity and classified policies.


2020 ◽  
Vol 32 (8) ◽  
pp. 430-435 ◽  
Author(s):  
Aizzat Mohd Nasurdin ◽  
Cheng Ling Tan ◽  
Sabrina Naseer Khan

Motivation is exceptionally crucial in influencing the quality of health care work outcomes. In view of the mounting challenges and stressful work environment faced by nurses, social support has been identified as an essential resource that helps promote their work motivation. The central aim of this study is to explore three forms of social support (perceived organizational support, perceived supervisory support, and perceived peer support) on nurses’ motivation. Cross-sectional data were collected via questionnaires from a sample of 354 nurses working in Malaysian public hospitals. The hypothesized model was tested using partial least squares method. Our results disclosed that all forms of social support have positive effects on motivation.


Author(s):  
Dong Jun Sung ◽  
Harshvardhan Singh ◽  
Seung-Bum Oh ◽  
SoJung Kim

The purpose of this cross-sectional study was to determine the differences in areal bone mineral density (aBMD) based on alcohol consumption behaviors, bone-loading history as assessed by a bone-specific physical activity questionnaire (BPAQ), and the body mass index (BMI). College-aged female students (N = 112) were recruited from the universities in Seoul and Gyeonggi province, South Korea. The aBMD of the lumbar spine and non-dominant side of the proximal femur (total hip, TH; femoral neck, FN; femoral trochanter, FT) were measured using dual energy X-ray absorptiometry (DXA). Alcohol consumption was determined by the frequency and amount of alcohol intake during the past 12 months using a self-reported questionnaire. The X-scan plus II was used to measure height (cm), body mass (kg), fat-free mass (FFM, kg), and % body fat. Drinking two or more times alcohol per week was associated with greater aBMD of the TH (p = 0.04–0.002) and FN (p = 0.043) compared to a lower frequency of alcohol consumption and 2–4 times per month, respectively. Based on the drinking amount per occasion, there were no significant group differences (p > 0.05) in aBMD at any of the sites. The highest group of total BPAQ had greater aBMD of the TH, FN, and FT versus the lowest (p = 0.023–0.009) and mid of total BPAQ groups (p = 0.004–0.009). Additionally, the highest group had greater aBMD of the lumbar spine compared to the mid group (p = 0.001). No significant group differences in aBMD at any of the sites were noted based on the BMI (p > 0.05). Young college-aged women with greater bone-loading physical activity showed greater aBMD at the TH, FN, FT, and lumbar spine, while a moderate alcohol intake was associated with greater aBMD of the TH and FN. These findings have clinical implications for young women who may not participate in high-impact physical activity and are binge drinkers.


BMJ Open ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. e026324 ◽  
Author(s):  
Onyekachi Ibenelo Anichukwu ◽  
Benedict Oppong Asamoah

ObjectiveTo examine the impact of maternal healthcare (MHC) utilisation on routine immunisation coverage of children in Nigeria.DesignIndividual level cross-sectional study using bivariate and multivariable logistic regression analyses to examine the association between MHC utilisation and routine immunisation coverage of children.SettingNigeria Demographic and Health Survey 2013.Participants5506 women aged 15–49 years with children aged 12–23 months born in the 5 years preceding the survey.Primary outcome measuresFully immunised children and not fully immunised children.ResultsThe percentage of children fully immunised with basic routine childhood vaccines by the age of 12 months was 25.8%. Antenatal care (ANC) attendance irrespective of the number of visits (adjusted OR (AOR)1–3 visits2.4, 95% CI 1.79 to 3.27; AOR4–7 visits3.2, 95% CI 2.52 to 4.13; AOR≥ 8 visits3.5, 95% CI 2.64 to 4.50), skilled birth attendance (SBA) (AOR 1.9, 95% CI 1.65 to 2.35); and maternal postnatal care (PNC) (AOR 1.7, 95% CI 1.46 to 2.06) had positive effects on the child being fully immunised after adjusting for covariates (except for each other, ie, ANC, SBA and PNC). Further analyses (adjusting stepwise for each MHC service) showed a mediation effect that led to the effect of PNC not being significant.ConclusionsThe percentage of fully immunised children in Nigeria was very low. ANC attendance, SBA and maternal PNC attendance had positive impact on the child being fully immunised. The findings suggest that strategies aimed at maximising MHC utilisation in Nigeria could be effective in achieving the national coverage target of at least 80% for routine immunisation of children.


Nutrients ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 2420
Author(s):  
Ji Eun Song ◽  
Joon Mo Kim ◽  
Mi Yeon Lee ◽  
Hye Joo Jang ◽  
Ki Ho Park

This study researched the association between alcohol consumption, intraocular pressure (IOP), and risk of open-angle glaucoma (OAG) using nationwide population-based cross-sectional data from the Korean population based survey. Information on alcohol intake was obtained by questionnaire and comprehensive ophthalmic examinations were performed. Among a total of 6057 participants, the prevalence of OAG was 4.4% (6.0% for men and 3.0% for women). Multivariate adjusted models showed that alcohol consumption showed significant relationship with changes in IOP. In sex-stratified analyses, alcohol consumption more than 2 times per week was associated with increased IOP in men without OAG, while in women with OAG drinking alcohol more than 4 times per week was associated with increased IOP. This study showed significant differences between men and women without glaucoma who consumed alcohol more than four times per week (p-value: 0.03). Our results suggest that alcohol consumption is associated with risk of elevated IOP depending on sex and presence of glaucoma in Koreans. Therefore, patients who need to control IOP should consider the effects of alcohol consumption.


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