Obstructive Hydrocephalus in Children: Predictive factors of ventriculocisternostomy dysfunction at the CHU of Conakry.

Author(s):  
Ibrahima Sory Souare ◽  
Mohamed Lamine Sylla ◽  
Ibrahima Sory Jnr Souaré ◽  
Hugues Ghislain Atakla ◽  
Mohamed Cherif ◽  
...  

Abstract Context and Objective: The treatment of hydrocephalus is surgical and uses two (2) main methods to date: ventriculoperitoneal shunt and endoscopic ventriculocisternostomy. The latter offers the advantage of avoiding the implantation of a foreign body (valve) in the body. However, there are sometimes dysfunctions that can lead to the evolutionary continuation of hydrocephalus. The objective of this study is to identify factors predictive of endoscopic ventriculocisternostomy dysfunction in cases of obstructive hydrocephalus in children at the University Hospital Center in Conakry.Methods and Materials: This is a mixed analytical study of 32 cases of children aged 0-15 years who received endoscopic ventriculocisternostomy during the study period. Outcomes were evaluated according to Drake and Canadian Pediatric Neurosurgery Group clinical criteria. Results: The hospital frequency was 17% and a sex ratio (M/F) of 1.13. Clinical signs were dominated by progressive macrocraniality (93.8%), bulging fontanel (84.4%), ectasia of scalp veins (68.8%). cerebrospinal fluid leakage (9.4%) was the most frequent post-operative complication. According to age, VCS was successful in 16 infants (55.2%) and dysfunction in 13 (44.8%) while 2 children (66.7%) were successful with VCS versus 1 (33.3%) with dysfunction. We recorded one case of death.Conclusion: The factors often associated with the dysfunction of the endoscopic ventriculocisternostomy found in this study are essentially: age, bulging fontanelle, ectasia of the scalp veins, arachnoid adhesions, closure of the Sylvius aqueduct and pulsation of the bottom of the third ventricle. In the absence of a statistically significant relationship, it would be useful to analyse these parameters closely on a much larger sample.

2009 ◽  
Vol 110 (1) ◽  
pp. 14-18 ◽  
Author(s):  
Joachim M. K. Oertel ◽  
Yvonne Mondorf ◽  
Michael R. Gaab

Obstructive hydrocephalus due to giant basilar artery (BA) aneurysm is a rare finding, and endoscopic treatment has not been reported. Here the authors present their experience with endoscopic third ventriculostomy (ETV) in obstructive hydrocephalus due to giant BA aneurysm. Between December 2000 and March 2007, 3 patients (2 men and 1 woman; age range 32–80 years) underwent an ETV for the treatment of obstructive hydrocephalus caused by a giant BA aneurysm. All 3 patients presented with cephalgia, nausea, vomiting, and a variable decrease in consciousness. An obstructive hydrocephalus caused by a giant BA aneurysm was found in each case as the underlying pathological entity. Intraoperatively, a narrowing of the third ventricle by upward displacement of the tegmentum was found in all 3 patients. A standard ETV was performed and included an inspection of the prepontine cisterns. The endoscopic treatment was successful in all patients with respect to clinical signs and radiological ventricular enlargement. No complications were observed. In all, the endoscopic ventriculostomy was proven to be a successful treatment option in obstructive hydrocephalus even if it is caused by untreated giant BA aneurysm.


2013 ◽  
Vol 62 (4) ◽  
pp. 261-267 ◽  
Author(s):  
Gláucia Renata Souza Rodrigues ◽  
Marcela Melquíades ◽  
Maria Alvim Leite ◽  
Maíra Barros Louro ◽  
Carmen Perches ◽  
...  

OBJECTIVE: To evaluate the biochemical and nutritional status of smokers in treatment for smoking cessation and its association with anthropometric parameters. METHODS: This is a cross-sectional study with convenience sample. Adult smokers were assessed at the start of treatment in the Interdisciplinary Center for Tobacco Research and Intervention of the University Hospital of the Federal University of Juiz de Fora (CIPIT/HU-UFJF). We evaluated the body mass index (BMI), conicity index (CI); waist circumference (WC), percentage of body fat (%BF), fasting glycemia, cortisol, insulin, total cholesterol (TC), LDL-c, HDL-c, triglycerides (TG) and metabolic syndrome (MS). RESULTS: Most participants (52.2%) had MS and high cardiovascular risk. The fasting glycemia was abnormal in 30.4%. There was a significant positive correlation between BMI and WC (r = 0.90; p = 0.0001), %BF (r = 0.79; p = 0.0001), CI (r = 0.65; p = 0.0001), glycemia (r = 0.42; p = 0.04) and TG (r = 0.47; p = 0.002). The CI presented positive correction with insulin (r = 0.60; p = 0.001), glycemia (r = 0.55; p = 0.007), TG (r = 0.54; p = 0.008) and %BF (r = 0.43; p = 0.004). Patients with longer duration of smoking had a higher risk of developing MS (OR = 9.6, p = 0.016). CONCLUSION: The smokers evaluated had increased risk for developing MS, especially those with longer duration of smoking, requiring urgent smoking cessation.


Author(s):  
Bishal Shrestha ◽  
Pritam Gurung ◽  
Sudan Dhakal ◽  
Pravesh Rajbhandari ◽  
Ranga Bahadur Basnet ◽  
...  

AbstractA 24-year-old gentleman presented to us with complaints of occasional headache for 2 years. Magnetic resonance imaging showed enhancing supra sellar mass with nonenhancing cystic components, extending superiorly up to the body of bilateral lateral ventricle, laterally displacing septum pellucidum, and compressing the third ventricle with obstructive hydrocephalus. Hormone profile depicted adrenocorticotropic hormone <5.00 pg/mL, growth hormone 1.32 ng/mL, insulin-like growth factor-1 <3.0 ng/mL. The patient underwent surgical resection. Histological finding was suggestive of ganglioglioma World Health Organization grade I. Customized immunohistochemistry panel was advised and revealed positive CD 56, NSE, and GFAP immunohistochemical stains. Gangliogliomas are less frequent neoplastic lesions confined to only a handful of case reports and studies. Accounting less than 2% of intracranial neoplasms, these lesions primarily affect those in the first 3 decades of their life. As ubiquitous it is in nature, we hereby present a case of ganglioglioma in a young adult male arising from septum pellucidum.


2018 ◽  
Vol 33 (3) ◽  
pp. 301-306 ◽  
Author(s):  
Ana Diklic ◽  
Doris Segota ◽  
Ingrid Belac-Lovasic ◽  
Slaven Jurkovic

The computed tomography has become a standard tool in radiation therapy treatment planning. Additionally, there is a growing awareness of the dose delivered to the part of the body outside the target volume. The ionizing radiation carries a stochastic risk of malignancy, therefore, the doses should be kept as low as reasonably achievable in order to provide an adequate information needed for the radiotherapy planning. The objective of this work was to set up the initial diagnostic reference levels and correlate to the image quality that would be used in the future optimization of localization scans. To quantify the doses from computed tomography localization scans at the University Hospital Rijeka, local diagnostic reference levels were established for five most common procedures of different anatomical regions; head, head and neck, pelvis, breast and thorax. The Computed Tomography Dose Index volumetric and the Dose-Length Product were used as dose indicators and scanning parameters were also recorded. The image quality assessment was performed for each set of images. The results were compared to the seldom published data in order to compare the clinical practice. The image quality for almost all of the body regions are scored as acceptable in average but require improvement. It is shown that the optimization of radiotherapy protocols is required. Therefore, these results will be used as a guideline for that process. The establishment of the national diagnostic reference levels for computed tomography localization procedures in radiation therapy is the next step and is currently an ongoing process.


Author(s):  
Layse A. SOUZA ◽  
Allan C. ARAÚJO ◽  
Ligiane L. SILVA ◽  
Poliana S. MENOLLI

Objective: To verify an association between weight and use of medications that lead to weight gain (MLGP) in a population of obese patients monitored in the Unified Health System. Methods: This is a retrospective descriptive sectional study with data from medical records of all patients. patients treated by the University Hospital Multiprofessional Service for obese patients who are candidates for bariatric surgery. The collection took place from January 2014 to March 2016. A weight-dependent variable, used in the body mass index (BMI) and degree of obesity and as independent variables of sex, age, education, income, number of diseases, number of drugs and number of MLGP. The association was calculated using the Ro Spearman correlation and the chi-square test. Results: 102 patients were studied, mostly women (87%), with a mean BMI of 45.9 kg / m2 (min 32.56 - maximum 70.98 kg / m2 SD = 6.43). The main comorbidities were systemic arterial hypertension (65.7%) and osteoarticular disorders (39.2%). The average number of drugs per patient was 4.3 and the most used class was for the renin-angiotensin system (67.3%). MLGP corresponds to 10.4% of the drugs used and 27.4% of the patients use them. MLGP patients used an average of 5.8 medications and the most prevalent classes were betablocking agents (60.6%), followed by medications used in diabetes (24.2%). Atenolol and a glibenclamide were the most used MLGP. The mean BMI of patients who used more than one MLGP was 51 kg / m2. Conclusion: There was no correlation between weight and the use of MLGP in this population. However, patients who used the MLGP combination had a higher BMI.


2011 ◽  
Vol 26 (S2) ◽  
pp. 1456-1456
Author(s):  
A.L. Morera-Fumero ◽  
E. Diaz-Mesa ◽  
P. Abreu-Gonzalez ◽  
A. Jimenez-Sosa ◽  
M. Henry-Benitez ◽  
...  

ObjectivesThe aim of this research is to study whether serum melatonin level is related with positive psychopathology in a sample of paranoid schizophrenia patients.Methods32 acutely paranoid schizophrenia patients admitted to the psychiatric ward of the University Hospital of the Canary Islands took part in the study. All patients met DSM-IV criteria for paranoid schizophrenia. 22 were males and 9 females. The mean age was 36.7 ± 10.3 (standard deviation). Blood was sampled by venipuncture at 12:00 and 24:00 hours after having rested in bed one hour. This was done to avoid the body postural effect on melatonin levels. Blood extractions were carried out during the first 48 hours after admission. Psychopathology was assessed by the positive subscale of the Positive and Negative Syndrome Scale (PANSS). Melatonin serum levels were measured by ELISA techniques. Pearson correlations between melatonin serum levels and PANSS positive scores at 24:00 and 12:00 hours at admission and discharge were carried out.ResultsThe only significant correlation, with a positive sign, was the item Conceptual Disorganisation (P2) with serum melatonin at 24:00 h (r = 0.355, p < 0.046).ConclusionsSerum melatonin levels may be used as a biological marker of conceptual disorganisation in paranoid schizophrenia inpatients.AcknowledgementThis study was partly supported by a grant (PI: 08/115) of the Fundacion Canaria de Investigacion y Salud (FUNCIS).


2017 ◽  
Vol 126 (1) ◽  
pp. 98-105 ◽  
Author(s):  
Daniele Marchioni ◽  
Matteo Alicandri-Ciufelli ◽  
Alessia Rubini ◽  
Babara Masotto ◽  
Giacomo Pavesi ◽  
...  

OBJECTIVE The aim of this study was to describe the first case series in which an exclusive endoscopic transcanal transpromontorial approach (EETTA) was used to treat small vestibular schwannomas (VSs) and meningiomas of the internal auditory canal (IAC). METHODS The authors performed a retrospective review of patients who had undergone surgery using an EETTA to the IAC at 2 university tertiary care referral centers during the period from November 2011 to January 2015. RESULTS Ten patients underwent surgery via an EETTA for the treatment of VS in the IAC at the University Hospital of Modena or the University Hospital of Verona. The patients had Koos Grade I or II tumors and American Academy of Otolaryngology–Head and Neck Surgery (AAO-HNS) Class D hearing status preoperatively. Gross-total resection was achieved in all patients. No major complications such as cerebrospinal fluid leakage or hemorrhage were reported. In 7 of 10 (70%) patients, facial nerve function was normal immediately after surgery (Rough Grading System [RGS] Grade I). Two patients presented with a transitory facial palsy immediately after surgery (RGS Grade II–III) but experienced complete recovery during the follow-up period. The mean follow-up was 10 months. CONCLUSIONS The EETTA proved to be successful for the removal of VS or meningioma involving the cochlea, fundus, and IAC, with possible lower complication rates and less invasive procedures than those for traditional microscopic approaches. The potential for the extensive and routine use of this approach in lateral and posterior skull base surgery will depend on the development of technology and surgical refinements and on the diffusion of skull base endoscopic skills among the otolaryngological and neurosurgical communities.


2021 ◽  
Author(s):  
Johan Courjon ◽  
Julie Contenti ◽  
Elisa Demonchy ◽  
Jacques Levraut ◽  
Pascal Barbry ◽  
...  

AbstractObjectivesThe variant 20I/501Y.V1, associated to a higher risk of transmissibility, emerged in Nice city (South East of France, French Riviera) during January 2021. The pandemic has resumed late December 2020 in this aera. A high incidence rate together with a fast turn-over of the main circulating variants, provided us the opportunity to analyze modifications in clinical profile and outcome traits.MethodsObservational study in the University hospital of Nice from December 2020 to February 2021. We analyzed data of sequencing of SARS-CoV-2 from the sewage collector and PCR screening from all positive samples at the hospital. Then, we described the characteristics of all COVID-19 patients admitted in the emergency department (ED) (n=1247) and those hospitalized in the infectious diseases ward or ICU (n=232). Demographic data, clinical signs and severity were recorded by the NEWS-2, SAPS-2 and SOFA scores were recorded and analyzed.Resultsthe UK-variant was absent in the area in December, then increasingly spread in January representing 59% of the PCR screening performed mid-February. The rate of patients over 65 years admitted to the ED decreased from 63% to 50% (p=0.001). The mean age of hospitalized patients in the infectious diseases ward decreased from 70.7 to 59.2 (p<0.001) while the proportion of patients without comorbidity increased from 16% to 42% (p=0.007). Neither the NEWS-2 score nor the main signs of clinical severity have changed over time.ConclusionSpread of the UK-variant in the South East of France affects younger and healthier patients.


Author(s):  
Alessandra Fernandes de Melo ◽  
Leila Amaral Gontijo ◽  
Andre Luis Pavan ◽  
Bianca Lautenschlager

As the time passes, the habits and the people's demands move. More and more, the people are complaining for better work conditions and life. (Dull and Weerdmeester, 1995). For that, its work conditions more and more need adaptations, seeking the health, the safety, the comfort, among other, that are the practical objectives of the ergonomics'. With the diffusion of the use of computers, the work positions with terminals of computers are turned frequent in industries and offices demanding like this a larger attention to the new works that it creates. (Iida, 1992). With this frequent use of the computer, it is demanded that the body adopts a static posture during the work day, with the fixed attention in the screen and the hands on the keyboard. Thus, the work in computer terminals can provoke consequences for the worker's health from the visual fatigue, muscular pains in the neck and shoulders, and pains in the tendons of the fingers, due to the ergonomic inadequacy and the demands of the task (Iida, 1992). Therefore, this article says respect to an ergonomic analysis in a work position, accomplished as requirement of the discipline of Ergonomic Engineering of the Work having been chosen the Section of General Registration (SRG) of the University Hospital (HU). It can intend the elaboration of a notebook of responsibilities of ergonomic recommendations that it will allow to establish the several specifications about the future situation, that says respect to the environmental factors and organization.


2021 ◽  
Vol 8 (3) ◽  
pp. 139-145
Author(s):  
Diakité Saikou Yaya ◽  
Baldé Habiboulaye ◽  
Diallo Abdoulaye ◽  
Camara Soriba Naby ◽  
Camara Fode Lansana ◽  
...  

Introduction: The aim of this study was to evaluate the results of one-stage colectomy versus two-stage colectomy at Conakry University Hospital. Methods: This was a retrospective study conducted at the University Hospital of Conakry from January 1, 2015 to December 31, 2019. All patients hospitalized and operated on in the Ignace Deen General Surgery and Donka Visceral Surgery departments for pelvic colon volvulus (PCV) who underwent colectomy during the study period were included. Results: We collected 87 cases of pelvic colon volvulus (PCV). The average age was 45.71 years with extremes of 5 years and 80 years with a male predominance of 82.83% and a sex ratio of 5.18. The morbidity was marked by 2 cases of anastomotic fistulas, 7 cases of parietal suppuration and 1 case of peristomal hemorrhage. 4 cases of death were noted in two-stage colectomy and 2 cases in one-stage colectomy. Conclusion: The occurrence of morbidity and mortality was not related to the type of colectomy. As our study does not allow us to affirm the superiority of one technique over the other, we recommend considering a future dynamic study that would take into account a larger sample.


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