Effective Components-Targets-Mechanism-Chinese Prescription Strategy (ETMC), A New Strategy for Chinese Prescription Development: A Case Study in Danlou Tablet

2020 ◽  
Author(s):  
Yongzhi Guo ◽  
Yingnan Jiang

Abstract Background: Chinese prescription is a combination medicine used by Chinese medical workers to treat various diseases and has saved countless human lives. By studying the effective substances, therapeutic targets, and mechanism of Chinese prescription, Western researchers can better understand the great value of Chinese prescription. Methods: In this study, a new strategy was proposed for the development of Chinese prescription: the effective components (E)-targets (T)-mechanism (M)-Chinese prescription (C) strategy, namely the ETMC strategy. Results: The proposed strategy used the chemical compositions of the Chinese prescription as the source of ligands to predict the corresponding targets for discovering the mechanism of Chinese prescription, which was helpful to further screen out effective substances from the chemical compositions of Chinese prescription. Here an example on development of Danlou tablet was performed to introduce the application of ETMC. Conclusions: A novel strategy for Chinese prescription development, ETMC, along with its application was provided in the current study, which contributed to the further development, wider application and internationalization of Chinese prescription.

Author(s):  
Dr. Harsha S. ◽  
Dr. Mamatha KV.

The optic nerve carries visual information from your eye to your brain. Optic neuritis is when your optic nerve becomes inflamed. Optic neuritis can flare up suddenly from an infection or nerve disease. The inflammation usually causes temporary vision loss that typically happens in only one eye. Those with Optic neuritis sometimes experience pain. As you recover and the inflammation goes away, your vision will likely return. There are no direct references in our classics regarding optic neuritis but can be contemplated as a condition by name Parimlayi Timira. The specific management as such is not cited but a transcendence approach can be done with adopting the treatment which has the ability to pacify the already occurred pathology and prevent the further development of the disease. One such interesting case study on Optic neuritis is elaborated here where in specific treatment modalities (Shodana, Shamana and Kriyakalpas) played role in pacifying the condition.


Author(s):  
Andrew Kahn ◽  
Mark Lipovetsky ◽  
Irina Reyfman ◽  
Stephanie Sandler

In the context of Sentimentalism in the 1770s, literary culture opened up to representations of human subjectivity. The chapter considers genres of poetry devoted to the themes of pleasure, death, and posterity. It also considers the spaces of poetry and modes of exchange, whether through the album, the salon, and the verse epistle. Two case studies explore the use of different literary forms in the further development of identity, individual and also authorial. The first looks at Radishchev’s experiment in writing a fictional diary as a psychological exercise. The second examines the tradition of imitation of Horace’s Monument poem in Russian poetry in the eighteenth century as well as by later poets, such as Pushkin and Brodsky. The case study shows how these Russian versions express changing ideas about imitation and originality as well as poets’ concern with posterity.


Author(s):  
Richen Liu ◽  
Hailong Wang ◽  
Chuyu Zhang ◽  
Xiaojian Chen ◽  
Lijun Wang ◽  
...  

Abstract Motivation Narrative visualization for scientific data explorations can help users better understand the domain knowledge, because narrative visualizations often present a sequence of facts and observations linked together by a unifying theme or argument. Narrative visualization in immersive environments can provide users with an intuitive experience to interactively explore the scientific data, because immersive environments provide a brand new strategy for interactive scientific data visualization and exploration. However, it is challenging to develop narrative scientific visualization in immersive environments. In this paper, we propose an immersive narrative visualization tool to create and customize scientific data explorations for ordinary users with little knowledge about programming on scientific visualization, They are allowed to define POIs (point of interests) conveniently by the handler of an immersive device. Results Automatic exploration animations with narrative annotations can be generated by the gradual transitions between consecutive POI pairs. Besides, interactive slicing can be also controlled by device handler. Evaluations including user study and case study are designed and conducted to show the usability and effectiveness of the proposed tool. Availability Related information can be accessed at: https://dabigtou.github.io/richenliu/


2021 ◽  
Vol 13 (14) ◽  
pp. 7906
Author(s):  
Nikola Medová ◽  
Lucie Macková ◽  
Jaromir Harmacek

This paper focuses on the dynamic of the recent upheaval in the tourism and hospitality sector due to the COVID-19 epidemic in Greece and Santorini island. It uses the case study of a country one-fourth of whose GDP consists of tourism. We compare the available statistical data showing the change in variables in the previous years with 2020 and look into the new challenges and opportunities posed by the drop in the numbers of visitors and flights. We focus mainly on the economic and social impact on the destination and possible future scenarios for further development in the area. Data show a significant effect of the pandemic on multiple variables, such as the long-term trend of the importance of tourism sector in GDP in Greece, the number of flights and visitors to Greece and Santorini island, and the contribution of tourism and travel to GDP. Based on the available data, we also construct three foresight scenarios that describe the possible futures for Santorini island in terms of the pandemic evolution. These scenarios may help various stakeholders and policymakers to be better prepared for different developments that may appear.


2017 ◽  
Vol 53 (68) ◽  
pp. 9470-9473 ◽  
Author(s):  
Krishna Kalyani Behara ◽  
Y. Rajesh ◽  
Yarra Venkatesh ◽  
Bhaskar Rao Pinninti ◽  
Mahitosh Mandal ◽  
...  

We report a new strategy, viz. cascade photocaging, for protecting diethylamine diazeniumdiolate (O2-position), a light sensitive molecule.


2014 ◽  
Vol 2014 ◽  
pp. 1-8 ◽  
Author(s):  
Aihua Zhang ◽  
Yongchao Wang ◽  
Chen Chen ◽  
Hamid Reza Karimi

Focus on this issue of disturbance and fault value is inevitable in data collection about analog circuit. A novel strategy is developed for analog circuit online performance evaluation based on fuzzy learning and double weighted support vector machine (DWMK-FSVM). First, the double weighted support vector regression machine is employed to be the indirect evaluation means, relied on the college analog electronic technology experiment to evaluate analog circuit. Second, the superiority of fuzzy learning also is addressed to realize active suppression to the fault values and disturbance parameters. Moreover, the multikernel RBF is employed by support vector regression machine to realize more flexibility online such as the bandwidths tuning. Numerical results, supported by the college analog circuit experiments, adopted OTL performance eight indexes, which were obtained via precision instrument evaluation in two years to construct training set and are then to be evaluated online based on DWMK-FSVM. Simulation results presented not only highlight precision of the evaluation strategy derived here but also illustrate its great robustness.


2021 ◽  
Vol 13 (1) ◽  
pp. 62-73
Author(s):  
Fernando Almeida ◽  
José Augusto Monteiro

Having an online presence is essential for any company regardless of its size and type of business. Users are currently striving to interact with companies through the web, regardless of their access device. In this sense, responsive web design emerged as a very useful technique that allows the dynamic adaptation of the design regardless of the size and resolution of the access device. Despite the unequivocal advantages associated with this technique, there are also limitations which turn this approach not feasible or advisable for all projects. This study, through the realization of five case studies, seeks to identify the main limitations of responsive design and responsive design frameworks. Additionally, this study suggests further development models that may be more effective in the dynamic adaptation of the design and contents according to the features of the access device, such as the adoption of adaptive design, use of native apps, and hybrid models.


2014 ◽  
Vol 24 (2) ◽  
pp. 181-204 ◽  
Author(s):  
Jeff McCarthy ◽  
Jennifer Rowley ◽  
Catherine Jane Ashworth ◽  
Elke Pioch

Purpose – The purpose of this paper is to contribute knowledge on the issues and benefits associated with managing brand presence and relationships through social media. UK football clubs are big businesses, with committed communities of fans, so are an ideal context from which to develop an understanding of the issues and challenges facing organisations as they seek to protect and promote their brand online. Design/methodology/approach – Due to the emergent nature of social media, and the criticality of the relationships between clubs and their fans, an exploratory study using a multiple case study approach was used to gather rich insights into the phenomenon. Findings – Clubs agreed that further development of social media strategies had potential to deliver interaction and engagement, community growth and belonging, traffic flow to official web sites and commercial gain. However, in developing their social media strategies they had two key concerns. The first concern was the control of the brand presence and image in social media, and how to respond to the opportunities that social media present to fans to impact on the brand. The second concern was how to strike an appropriate balance between strategies that deliver short-term revenue, and those that build longer term brand loyalty. Originality/value – This research is the first to offer insights into the issues facing organisations when developing their social media strategy.


Land Science ◽  
2020 ◽  
Vol 2 (2) ◽  
pp. p21
Author(s):  
Vera Iváncsics ◽  
Krisztina Filepné Kovács

Recently the planning of green infrastructure (GI) has become a general practice around metropolis (Paris, München, Budapest, etc). A complex methodology is required that goes beyond the scope of traditional green surface systems. However, there are various policy implications in the EU, the smaller towns are lagging to apply them. The paper presents a potential evaluation method through the case study of Keszthely, HU. As Keszthely at Balaton Riviera, is a popular touristic target of CEE, the environmental planning is an essential part of sustainable development. After a literature analyses of assessment methods of GI and ecosystem services, the aspects of GI have been valued on grade scales, based on field surveys and indicators. The current status of the GI was surveyed which is a base for further development and monitoring activities. The paper introduces the methodology, which contributes to preservation of ecosystems.


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