scholarly journals Status of Antimicrobial Stewardship Implementation in Some Egyptian Hospitals, a Cross-sectional Study

2021 ◽  
Author(s):  
Noha Alaa Hamdy ◽  
Nahla Hesham Kandil ◽  
Ahmed Noby Amer
Keyword(s):  
Antimicrobial Stewardship ◽  
Outcome Measurement ◽  
Action Plan ◽  
Antibiotic Use ◽  
Cross Sectional Study ◽  
Future Application ◽  
Sectional Study ◽  
Cross Sectional ◽  
It Support ◽  
Restriction Methods

Abstract Background: Antimicrobial stewardship (ASP) aims to stopping or slowing emergence of antimicrobial resistant strains. After initiation of National action plan on antimicrobial resistance (AMR) in Egypt, there were several initiatives by hospitals to implement ASP but no formal assessment was performed.Objective & setting: This study attempts to assess the extent of ASP application in different Egyptian hospitals; stewardship knowledge & implementation in selected hospitals. Method: A cross-sectional study was conducted to assess stewardship knowledge & implementation in selected hospitals in Egypt. Main outcome measure: Core elements of the survey included Hospital Description, ASP committee, ASP Activities (including training, restriction methods and outcome measurement), reporting antibiotic use, antibiogram, information technology (IT) support, ASP restriction methods and ASP Future ApplicationResults: The study included many aspects regarding hospital description; all types of hospitals were involved. Most of hospitals (61.8%) implemented an ASP program while 38.2% did not; 71.4 % of the later are planning for future Antimicrobial stewardship application. 22 hospitals (48.5%) reported having facility-specific antibiogram on regular basis. 13 hospitals (37.1%) reported receiving antimicrobial reports on regular basis. 15 hospitals (42.9%) reported having one or more computer programs already in use. The monitoring activities included resistance patterns, infection rates, length of stay, mortality rate & reported adverse drug reactions. Only 20% of the hospitals included in this study reported having an ASP training program. Conclusion: Egyptian hospitals have a fairly good implementation, improvements need to include IT support programs, healthcare members cooperation, monitoring outcomes & infectious disease (ID) consultations.

scholarly journals Assessing Knowledge and Perception Regarding Antimicrobial Stewardship and Antimicrobial Resistance in University Students of Pakistan: Findings and Implications

Antibiotics ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 866
Author(s):  
Iltaf Hussain ◽  
Nisa Yousaf ◽  
Sana Haider ◽  
Pervisha Jalil ◽  
Muhammad Usman Saleem ◽  
...  
Keyword(s):  
Antimicrobial Resistance ◽  
University Students ◽  
Antimicrobial Stewardship ◽  
Antibiotic Use ◽  
Cross Sectional Study ◽  
Dosing Regimen ◽  
Student Knowledge ◽  
Chi Square ◽  
Cross Sectional ◽  
Self Administered Questionnaire

The irrational use of antimicrobials has enormously contributed to antimicrobial resistance (AMR) globally and especially in the developing world. To assess the knowledge and perception regarding AMR and antimicrobial stewardship (AMS), a descriptive cross-sectional study was carried out in university students enrolled in pharmacy, veterinary, and biology programs by using an online self-administered questionnaire. The Chi-square and Fisher exact tests (where applicable) were performed to assess the association of the demographics with the students’ knowledge and perception regarding AMR and AMS. A total of 496 students completed the questionnaire, among which, 85.7% of the participants were familiar with the term AMR and 79.4% of the participants correctly identified a poorly designed dosing regimen as a contributing factor towards AMR. The majority of participants (57.9%) were familiar with the term AMS and 86.5% were aware of the aim of AMS. The participants showed good knowledge regarding AMR and AMS, but to further improve student knowledge and perception of AMS and AMR, it is suggested that dedicated modules on antibiotic use and AMS should be incorporated into the curricula of these undergraduate and postgraduate programs.

scholarly journals Antibiotics stewardship in Ghana: a cross-sectional study of public knowledge, attitudes, and practices

2020 ◽  
Author(s):  
Tamara Jimah ◽  
Ama P. Fenny ◽  
Oladele Ogunseitan
Keyword(s):  
Antibiotic Resistance ◽  
Inappropriate Medication ◽  
Antibiotic Use ◽  
Antibiotic Consumption ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Attitudes And Practices ◽  
Individual Knowledge ◽  
Knowledge Attitudes And Practices

Abstract Background Antibiotic resistance is a major contributing factor to global morbidity and mortality and is associated with inappropriate medication use. However, the level of antibiotic consumption and knowledge about antibiotic resistance in Ghana is inadequately quantified. Our study identifies strategies for improved stewardship of antibiotics to prevent the proliferation of resistant pathogens by assessing the level of antibiotic knowledge, attitudes, and consumption behaviors by region, gender, age, and education in rural and urban Ghana. Methods A cross-sectional study was conducted in 12 communities in the urban Greater Accra and rural Upper West regions of Ghana. A questionnaire survey was administered to 400 individuals aged 18 years and older in selected locations during September-October 2018 to gather data on individual knowledge, attitudes, and practices concerning antibiotics and antibiotic resistance. Multivariate analysis was used to investigate the association between demographic characteristics and knowledge, attitudes, and related behaviors. Results Over 30% (125/400) had not received a doctor’s prescription during their last illness. Seventy percent (278/400) had taken at least one antibiotic in the year prior to the survey. The top five frequently used antibiotics were Amoxicillin , Amoxicillin-clavulanic acid , Ampicillin , Ciprofloxacin , and Metronidazole . Women and older adults had higher knowledge compared to their respective counterparts (p<0.01). Furthermore, prudent antibiotic use was significantly more prevalent in women than men (p<0.05). Although no regional differences were found in overall knowledge, compared to urban residents, individuals residing in rural settings exhibited higher knowledge about the ineffectiveness of antibiotics for viruses like the cold and HIV/AIDS (p<0.001). Two hundred and fifty-two (63%) respondents were unaware of antibiotic resistance. There was generally a low level of self-efficacy among participants regarding their role in preserving the effectiveness of antibiotics. Conclusion Antibiotic knowledge, attitudes, and use varied significantly across demographics, suggesting a context-specific approach to developing effective community interventions.

scholarly journals Assessment of General Public’s Knowledge and Opinions towards Antibiotic Use and Bacterial Resistance: A Cross-Sectional Study in an Urban Setting, Rufisque, Senegal

Pharmacy ◽  
2018 ◽  
Vol 6 (4) ◽  
pp. 103 ◽  
Author(s):  
Oumar Bassoum ◽  
Ndèye Sougou ◽  
Mayassine Diongue ◽  
Mamadou Lèye ◽  
Mouhamad Mbodji ◽  
...  
Keyword(s):  
Bacterial Resistance ◽  
Public Health Problem ◽  
Antibiotic Use ◽  
Cross Sectional Study ◽  
Urban Setting ◽  
Major Public Health Problem ◽  
Sources Of Information ◽  
Sectional Study ◽  
Cross Sectional ◽  
Awareness Campaigns

Background: Bacterial resistance is a major public health problem worldwide. One solution to this scourge is to sensitize the general public on rational use of antibiotics. Our goal was to assess people’s knowledge and opinions about antibiotic use and bacterial resistance in an urban setting. Method: We performed a cross-sectional study. A convenience sampling was done. A questionnaire was administered to 400 persons during face-to-face interviews. Results: Most respondents thought that antibiotics are effective against colds/flu (69.8%), cough (72.3%) and sore throat (64.4%). At the same time, 42.8% stated that antibiotic therapy can be stopped as soon as the symptoms disappear. Only 8.8% and 41.8% of people knew that handwashing and vaccination prevented bacterial resistance. Globally, 7% of people had a good knowledge. Socio-demographic variables were not associated with the level of knowledge. The main sources of information were entourage and pharmacy staff. Regarding the opinions, 78.3% of surveyed participants the people thought that that people overuse antibiotics. Additionally, 28% said that they have no role to play against bacterial resistance. Conclusion: People living in an urban setting had a low knowledge about antibiotic use and bacterial resistance. There is a need to implement awareness campaigns. Further studies on population practices toward antibiotic use are necessary.

scholarly journals Public awareness regarding the use and resistance of antibiotics: A cross-sectional study among Nepalese adults in Kathmandu valley

2018 ◽  
Vol 6 (3) ◽  
pp. 96-101
Author(s):  
Satish Kumar Deo ◽  
Sita Rijal ◽  
Tulza K.C
Keyword(s):  
Antibiotic Resistance ◽  
Public Awareness ◽  
Study Finding ◽  
Antibiotic Use ◽  
Cross Sectional Study ◽  
Public Health Issue ◽  
Sectional Study ◽  
Cross Sectional ◽  
Interview Method ◽  
Drug Classes

Background: Antibiotics are considered to be among the most commonly sold drug classes globally. Antibiotic resistance is a recognized public health issue at the local, national and global levels.Objectives: The aim of this study was to identify awareness of general public regarding the use and resistance of antibiotics.Methodology: A descriptive cross-sectional study was conducted in Kathmandu in November 2016 using a quantitative questionnaire among 120 adult people aged 20–60 years. Convenience sampling method was used and information on use of antibiotics and resistance was obtained using semi-structured questionnaire through interview method. Descriptive statistics was done to describe the respondent’s level of awareness regarding use of antibiotics and resistance.Results: Among the total respondents, majority had incorrect awareness as regards to action, reasons for using antibiotics, possible side effects of the antibiotic. Seventy one percent of the respondents had not heard about antibiotic resistance. The study finding showed that about 66.7% of the participants had inadequate awareness towards use and resistance of antibiotics.Conclusion: The findings demonstrate that the overall awareness on antibiotic use and resistance is poorly understood among our respondents. This information can be utilized in future educational and antibiotic resistance awareness raising campaigns.

Factors influencing non-prescription sales of antibiotics among patent and proprietary medicine vendors in Kano, Nigeria: a cross-sectional study

2020 ◽  
Vol 35 (7) ◽  
pp. 819-828
Author(s):  
Abdu A Adamu ◽  
Muktar A Gadanya ◽  
Rabiu I Jalo ◽  
Olalekan A Uthman ◽  
Charles S Wiysonge
Keyword(s):  
Complex Dynamics ◽  
Health Workers ◽  
Antibiotic Use ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Retail Outlets ◽  
Training Programmes ◽  
Multilevel Logistic Regression Model ◽  
The Relationship

Abstract Patent and proprietary medicine vendors (PPMVs) increase access to antibiotics through non-prescription sales in their drug retail outlets. This fosters irrational antibiotic use among people, thus contributing to the growing burden of resistance. Although training programmes on antibiotic use and resistance exist, they have disproportionately targeted health workers in hospital settings. It’s unclear if there is a relationship between such trainings and non-prescription sales of antibiotics among PPMVs which are more embedded in communities. Therefore, a cross-sectional study was conducted to elicit the determinants of non-prescription antibiotic sales among PPMVs in Kano metropolis, Nigeria. Through brainstorming, causal loop diagrams (CLDs) were used to illustrate the dynamics of factors that are responsible for non-prescription antibiotic sales. Multilevel logistic regression model was used to determine the relationship between training on antibiotic use and resistance and non-prescription antibiotic sales, after controlling for potential confounders. We found that two-third (66.70%) of the PPMVs reported that they have sold non-prescribed antibiotics. A total of three CLDs were constructed to illustrate the complex dynamics of the factors that are related to non-prescription antibiotic sales. After controlling for all factors, PPMVs who reported that they had never received any training on antibiotic use and resistance were twice as more likely to sell antibiotic without prescription compared with those who reported that they have ever received such training (OR = 2.07, 95% CI: 1.27–3.37). This finding suggests that there is an association between training on antibiotic use and resistance and non-prescription sales of antibiotics. However, the complex dynamics of the factors should not be ignored as it can have implications for the development of intervention programmes. Multifaceted and multicomponent intervention packages (incorporating trainings on antibiotic use and resistance) that account for the inherent complexity within the system are likely to be more effective for this setting.

scholarly journals Association of β-Lactam Allergy Documentation and Prophylactic Antibiotic Use in Surgery: A National Cross-Sectional Study of Hospitalized Patients

2020 ◽  
Author(s):  
Christie M Bertram ◽  
Michael Postelnick ◽  
Christian M Mancini ◽  
Xiaoqing Fu ◽  
Yuqing Zhang ◽  
...  
Keyword(s):  
United States ◽  
Adverse Events ◽  
Prophylactic Antibiotic ◽  
Antibiotic Use ◽  
The United States ◽  
Cross Sectional Study ◽  
Site Infection ◽  
Sectional Study ◽  
Surgical Prophylaxis ◽  
Cross Sectional

Abstract Alternative antibiotics for surgical prophylaxis are associated with increased adverse events and surgical site infection compared to cefazolin. In a sample of perioperative inpatients from 100 hospitals in the United States, cefazolin was 9-fold less likely to be used in patients with a documented β-lactam allergy whereas clindamycin was 45-fold more likely.

scholarly journals Prevalence ofStaphylococcus aureuscarriage among dogs and their owners

2007 ◽  
Vol 136 (7) ◽  
pp. 953-964 ◽  
Author(s):  
M. V. BOOST ◽  
M. M. O'DONOGHUE ◽  
A. JAMES
Keyword(s):  
Health Care ◽  
Health Care Workers ◽  
Case Reports ◽  
Nasal Carriage ◽  
Antibiotic Use ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Human Contact ◽  
Care Workers

SUMMARYCase reports have indicated transmission ofStaphylococcus aureusbetween humans and pets. We investigated associations between level of contact between dog and owner, andS. aureuscolonization. In a cross-sectional study, nasal carriage and antibiotic susceptibility ofS. aureuswas determined for 830 dogs and 736 owners. Relatedness of isolates was investigated using antibiograms and pulsed-field gel electrophoresis (PFGE). Associations between carriage and demographics or amount of contact between owners and dogs were documented.S. aureuswas isolated in 24% of humans and 8·8% of dogs. Antibiotic resistance was significantly more common in canine isolates. Of 17 owner/dog colonized pairs, six were indistinguishable by PFGE. Colonization of dogs was not associated with close human contact, but was strongly associated with health-care occupations (OR 3·29, 95% CI 1·49–7·26,P=0·002). In outbreak situations health-care workers' pets should be considered as a source ofS. aureus. High rates of resistance indicate increased monitoring of antibiotic use in veterinary practice is needed.

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