scholarly journals Prevalence of asymptomatic visceral leishmaniasis in human and dog, Benishangul Gumuz regional state, Western Ethiopia

2020 ◽  
Author(s):  
Shibabaw Bejano ◽  
Girma Shumie ◽  
Ashwani Kumar ◽  
Eyuel Asemahagn ◽  
Demekech Damte ◽  
...  

Abstract Background: Benishangul-Gumuz region is an important development corridor in Ethiopia. The large-scale projects; the great renaissance dam, mining and agriculture entailed huge environmental modification and settlement pattern changes. Detail epidemiological information of VL in the region is unknown. Materials and Methods: A cross sectional study to assess the epidemiology and risk factors associated with Leishmania infection. Leishmanin skin test (LST) was done for 1342 participants, and for 253 of them rK39 and DAT were done. Thirty-six dogs owned by households with LST positive member(s) were rK39 and DAT tested. A pretested questionnaire was used to capture individual and household characteristics. Results: Of the 89.2% (1197/1342) who availed themselves for LST reading 6.0% were positive. The rk39 and DAT positivity among the 253 tested were 3.2% and 5.9% respectively. In dogs, positivity rates by rK39 and DAT were 13.9% and 5.6% respectively. Of the household and individual risk factors presence of dog in household (P=0.005), male sex (0.003), residence woreda (0.000) and occupation (0.023) showed a strong positive association with LST positivity. Individuals who lived in household who owned dogs were 2.6 times more likely to be LST positive (AOR = 2.6; 95%CI= 1.54, 4.40). Being female decreased by 0.38 times the probability of being LST positive (AOR = 0.38; 95%CI= 0.20, 0.72). Living in Guba and Kurmuk has 4.7 (AOR=4.74, 95% CI 1.83, 12.31) and 5.9 (AOR=5.85, 95%CI 2.27, 15.09) times more risk of being infected. Conclusions: We demonstrated presence of active VL transmission in the areas. Thus, we underline the need to establish the responsible vector(s) and reservoir(s) for comprehensive early containment plan to prevent potentially harmful public health and economic consequence.

2020 ◽  
Author(s):  
Shibabaw Bejano ◽  
Girma Shumie ◽  
Ashwani Kumar ◽  
Eyuel Asemahagn ◽  
Demekech Damte ◽  
...  

Abstract Background Benishangul-Gumuz region is an important development corridor in Ethiopia. The large-scale projects; the great renaissance dam, mining and agriculture entailed huge environmental modification and settlement pattern changes. Detail epidemiological information of VL in the region is unknown. Materials and Methods A cross sectional study to assess the epidemiology and risk factors associated with asymptomatic VL. Leishmanin skin test (LST) was done for 1342 participants, and for 253 of them rK39 and DAT were done. Thirty-six dogs owned by households with LST positive member(s) were rK39 and DAT tested. A pretested questionnaire was used to capture individual and household characteristics. Results Of the 89.2% (1197/1342) who availed themselves for LST reading 6.0% were positive. The rk39 and DAT positivity among the 253 tested were 3.2% and 5.9% respectively. In dogs, positivity rates by rK39 and DAT were 13.9% and 5.6% respectively. Of the household and individual risk factors presence of dog in household (P = 0.005), male sex (0.003), residence woreda (0.000) and occupation (0.023) showed a strong positive association with LST positivity. Individuals who lived in household who owned dogs were 2.6 times more likely to be LST positive (AOR = 2.6; 95%CI = 1.54, 4.40). Being female decreased by 0.38 times the probability of being LST positive (AOR = 0.38; 95%CI = 0.20, 0.72). Living in Guba and Kurmuk has 4.7 (AOR = 4.74, 95% CI 1.83, 12.31) and 5.9 (AOR = 5.85, 95%CI 2.27, 15.09) times more risk of being infected. Conclusions We demonstrated presence of active VL transmission in the areas. Thus, we underline the need to establish the responsible vector(s) and reservoir(s) for comprehensive early containment plan to prevent potentially harmful public health and economic consequence.


BMJ Open ◽  
2017 ◽  
Vol 7 (8) ◽  
pp. e015755 ◽  
Author(s):  
Daniele B Vinholes ◽  
Sérgio L Bassanesi ◽  
Hilton de Castro Chaves Junior ◽  
Carlos Alberto Machado ◽  
Ione M F Melo ◽  
...  

BackgroundExposure to risk factors for hypertension may be influenced by the characteristics of the workplace, where workers spend most of their daily time.ObjectivesTo evaluate the association between features of the companies, particularly the presence of facilities to provide meals, and of population characteristics and the prevalence of hypertension, taking into account individual risk factors for hypertension.Material and methodsThis multilevel analysis was based on a cross-sectional study with individual and company data from the SESI(Serviço Social da Indústria–Social Service of Industries)study and population-based data from the national census statistics. Workers aged ≥15 years were randomly selected from small (20–99), medium (100–499) and large (≥500 employees) companies per state using multistage sampling. Logistic regression was used to analyse the association between hypertension and individual, workplace and population variables, with odds ratios (ORs; 95% CI) adjusted for three-level variables.Results4818 Workers from 157 companies were interviewed and their blood pressure, weight and height were measured. Overall, 77% were men, aged 35.4 ±10.7 years, with 8.7 ±4.1 years of schooling and mostly worked in companies with a staff canteen (66%). Besides individual characteristics—being male, ageing, low schooling, alcohol abuse and higher BMI—a workplace with no staff canteen (OR=1.28; 95% CI 1.08 to 1.52), small companies (OR=1.31; 95% CI 1.07 to 1.60) and living in cities with higher economic inequality (OR=1.47; 95% CI 1.23 to 1.76) were associated with a higher risk for hypertension.ConclusionAmong Brazilian workers, the prevalence of hypertension is associated with individual risk factors, lack of a canteen at the workplace, small companies and higher economic inequalities of cities. These three-level characteristics help to interpret differences in the prevalence of hypertension between regions or countries.


2014 ◽  
Vol 11 (5) ◽  
pp. 942-949 ◽  
Author(s):  
Felipe Vogt Cureau ◽  
Paola Duarte ◽  
Daniela Lopes dos Santos ◽  
Felipe Fossati Reichert

Background:Few studies have investigated the prevalence and correlates of risk factors for noncommunicable diseases among Brazilian adolescents. We evaluated the clustering of risk factors and their associations with sociodemographic variables.Methods:We used a cross-sectional study carried out in 2011 comprising 1132 students aged 14–19 years from Santa Maria, Brazil. The cluster index was created as the sum of the risk factors. For the correlates analysis, a multinomial logistic regression was used. Furthermore, the observed/expected ratio was calculated.Results:Prevalence of individual risk factors studied was as follows: 85.8% unhealthy diets, 53.5% physical inactivity, 31.3% elevated blood pressure, 23.9% overweight, 22.3% excessive drinking alcohol, and 8.6% smoking. Only 2.8% of the adolescents did not present any risk factor, while 21.7%, 40.9%, 23.1%, and 11.5% presented 1, 2, 3, and 4 or more risk factors, respectively. The most prevalent combination was between unhealthy diets and physical inactivity (observed/expected ratio =1.32; 95% CI: 1.16–1.49). Clustering of risk factors was directly associated with age and inversely associated with socioeconomic status.Conclusions:Clustering of risk factors for noncommunicable diseases is high in Brazilian adolescents. Preventive strategies are more likely to be successful if focusing on multiple risk factors, instead of a single one.


BMJ Open ◽  
2019 ◽  
Vol 9 (4) ◽  
pp. e024143 ◽  
Author(s):  
Carley Riley ◽  
Brita Roy ◽  
Jeph Herrin ◽  
Erica Spatz ◽  
Mark T Silvestri ◽  
...  

ObjectiveTo determine if preterm birth, defined as gestational age <37 weeks, is lower for women living in counties with higher well-being, after accounting for known individual risk factors.DesignCross-sectional study of all US births in 2011.ParticipantsWe obtained birth data from the National Center for Health Statistics which included 3 938 985 individuals.Main outcomes measuresPrimary outcome measure was maternal risk of preterm delivery by county; primary independent variable was county-level well-being as measured by the Gallup-Sharecare Well-Being Index (WBI).ResultsWomen living in counties with higher population well-being had a lower rate of preterm delivery. The rate of preterm birth in counties in the lowest WBI quintile was 13.1%, while the rate of preterm birth in counties in the highest WBI quintile was 10.9%. In the model adjusted for maternal risk factors (age, race, Hispanic ethnicity, smoking status, timing of initiation of prenatal visits, multiparity, maternal insurance payer), the association was slightly attenuated with an absolute difference of 1.9% (95% CI 1.7% to 2.1%; p<0.001).ConclusionsPregnant women who live in areas with higher population well-being have lower risk of preterm birth, even after accounting for individual risk factors.


2021 ◽  
Vol 10 (6) ◽  
pp. 1211
Author(s):  
Li-Te Lin ◽  
Kuan-Hao Tsui

The relationship between serum dehydroepiandrosterone sulphate (DHEA-S) and anti-Mullerian hormone (AMH) levels has not been fully established. Therefore, we performed a large-scale cross-sectional study to investigate the association between serum DHEA-S and AMH levels. The study included a total of 2155 infertile women aged 20 to 46 years who were divided into four quartile groups (Q1 to Q4) based on serum DHEA-S levels. We found that there was a weak positive association between serum DHEA-S and AMH levels in infertile women (r = 0.190, p < 0.001). After adjusting for potential confounders, serum DHEA-S levels positively correlated with serum AMH levels in infertile women (β = 0.103, p < 0.001). Infertile women in the highest DHEA-S quartile category (Q4) showed significantly higher serum AMH levels (p < 0.001) compared with women in the lowest DHEA-S quartile category (Q1). The serum AMH levels significantly increased across increasing DHEA-S quartile categories in infertile women (p = 0.014) using generalized linear models after adjustment for potential confounders. Our data show that serum DHEA-S levels are positively associated with serum AMH levels.


2020 ◽  
Vol 9 ◽  
pp. 117957271989706
Author(s):  
Kirill Alekseyev ◽  
Alex John ◽  
Andrew Malek ◽  
Malcolm Lakdawala ◽  
Nikhil Verma ◽  
...  

Background: CrossFit is an increasingly popular, rapidly growing exercise regimen. Few studies have evaluated CrossFit-associated musculoskeletal injuries on a large scale. This study explores such injuries and associated risk factors in detail. Objective: To identify the most common musculoskeletal injuries endured during CrossFit training among athletes at different levels of expertise. Design: Survey-based retrospective cross-sectional study. Setting: Distribution at CrossFit gyms in the United States and internationally. Also published on active online forums. Participants: A total of 885 former and current CrossFit athletes. Methods: Institutional review board-approved 33-question Web-based survey focused on CrossFit injuries and associated risk factors. Survey submissions were accepted for a period of 6 months. Main outcome measurements: Specific injuries with associated workouts, risk factors that affected injury including (1) basic demographics, (2) regional differences in reported injuries, (3) training intensity, and (4) expertise level at time of injury. Results: Of the 885 respondents, 295 (33.3%) were injured. The most common injuries involved the back (95/295, 32.2%) and shoulder (61/295, 20.7%). The most common exercises that caused injury were squats (65/295, 22.0%) and deadlifts (53/295, 18.0%). Advanced-level (64/295, 21.7%) athletes were more significantly injured than beginner-level (40/295, 13.6%) athletes. International participants were 2.2 times more likely than domestic US participants to suffer injury. Individuals with 3+ years of CrossFit experience were 3.3 times more likely to be injured than those with 2 or less years of experience. Participants who trained for 11+ h/week were significantly more likely to be injured than those who trained less than or equal to 10 h/week. Conclusions: As CrossFit becomes more popular, it is important to monitor the safety of its practitioners. Further studies are needed to explore how to lower this injury prevalence of 33.3%. Areas to focus on include factors that have caused the regional (international vs US states) differences, level of expertise/experience differences (advanced level vs intermediate and beginner levels), and stretching routine modifications.


2019 ◽  
Vol 23 (3) ◽  
pp. 446-456 ◽  
Author(s):  
Eva Kiesswetter ◽  
Miriam G Colombo ◽  
Christa Meisinger ◽  
Annette Peters ◽  
Barbara Thorand ◽  
...  

AbstractObjective:The origin of malnutrition in older age is multifactorial and risk factors may vary according to health and living situation. The present study aimed to identify setting-specific risk profiles of malnutrition in older adults and to investigate the association of the number of individual risk factors with malnutrition.Design:Data of four cross-sectional studies were harmonized and uniformly analysed. Malnutrition was defined as BMI < 20 kg/m2 and/or weight loss of >3 kg in the previous 3–6 months. Associations between factors of six domains (demographics, health, mental function, physical function, dietary intake-related problems, dietary behaviour), the number of individual risk factors and malnutrition were analysed using logistic regression.Setting:Community (CD), geriatric day hospital (GDH), home care (HC), nursing home (NH).Participants:CD older adults (n 1073), GDH patients (n 180), HC receivers (n 335) and NH residents (n 197), all ≥65 years.Results:Malnutrition prevalence was lower in CD (11 %) than in the other settings (16–19 %). In the CD sample, poor appetite, difficulties with eating, respiratory and gastrointestinal diseases were associated with malnutrition; in GDH patients, poor appetite and respiratory diseases; in HC receivers, younger age, poor appetite and nausea; and in NH residents, older age and mobility limitations. In all settings the likelihood of malnutrition increased with the number of potential individual risk factors.Conclusions:The study indicates a varying relevance of certain risk factors of malnutrition in different settings. However, the relationship of the number of individual risk factors with malnutrition in all settings implies comprehensive approaches to identify persons at risk of malnutrition early.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Xufei Zhang ◽  
Zhiwei Wang ◽  
Jun Chen ◽  
Peige Wang ◽  
Suming Luo ◽  
...  

Abstract Purposes Surgical site infection (SSI) after colorectal surgery is a frequent complication associated with the increase in morbidity, medical expenses, and mortality. To date, there is no nationwide large-scale database of SSI after colorectal surgery in China. The aim of this study was to determine the incidence of SSI after colorectal surgery in China and to further evaluate the related risk factors. Methods Two multicenter, prospective, cross-sectional studies covering 55 hospitals in China and enrolling adult patients undergoing colorectal surgery were conducted from May 1 to June 30 of 2018 and the same time of 2019. The demographic and perioperative characteristics were collected, and the main outcome was SSI within postoperative 30 days. Multivariable logistic regressions were conducted to predict risk factors of SSI after colorectal surgery. Results In total, 1046 patients were enrolled and SSI occurred in 74 patients (7.1%). In the multivariate analysis with adjustments, significant factors associated with SSI were the prior diagnosis of hypertension (OR, 1.903; 95% confidence interval [CI], 1.088–3.327, P = 0.025), national nosocomial infection surveillance risk index score of 2 or 3 (OR, 3.840; 95% CI, 1.926–7.658, P < 0.001), laparoscopic or robotic surgery (OR, 0.363; 95% CI, 0.200–0.659, P < 0.001), and adhesive incise drapes (OR, 0.400; 95% CI, 0.187–0.855, P = 0.018). In addition, SSI group had remarkably increased length of postoperative stays (median, 15.0 d versus 9.0d, P < 0.001), medical expenses (median, 74,620 yuan versus 57,827 yuan, P < 0.001), and the mortality (4.1% versus 0.3%, P = 0.006), compared with those of non-SSI group. Conclusion This study provides the newest data of SSI after colorectal surgery in China and finds some predictors of SSI. The data presented in our study can be a tool to develop optimal preventive measures and improve surgical quality in China.


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