scholarly journals Prevalence of Erectile Dysfunction According to Chronic Comorbid Health Conditions: a Cross-sectional Study.

Author(s):  
Giuseppe Lisco ◽  
Nicola Bartolomeo ◽  
Maria Isabella Ramunni ◽  
Anna De Tullio ◽  
Matteo Domenico Carbone ◽  
...  

Abstract Introduction. The prevalence of erectile dysfunction (ED) increases along with the burden of chronic diseases. This retrospective study aimed to assess the prevalence and severity of ED according to the levels of chronic comorbidities.Material and Methods. Two hundred twenty-two outpatients referred to the Outpatients Clinic of Endocrinology and Metabolic Disease of Conversano Hospital (Italy) with ED complaints from January 2018 to December 2019 were retrospectively eligible for this cross-sectional study. The ED severity and comorbidities burden were assessed by the 5-item International Index of Erectile Function questionnaire (IIEF-5) and Charlson comorbidity index (CCI). A modified index (mCCI) was developed to integrate other common risk factors for ED and was compared to the original tool. The primary outcome was to assess the prevalence of ED according to the severity of CCI. The secondary outcomes included the correlation between 1) IIEF-5 and total testosterone (TT); 2) CCI and TT; 3) IIEF-5 and CCI. Finally, the performance of the CCI and mCCI were compared.Results. The overall prevalence of ED increased along with the CCI score: 45% (5 on 11) for CCI=0; 95% (19 on 20) for CCI=1; 91% (29 on 32) for CCI=2; 99% (158 on 160) for CCI≥3 (p<.0001) Moreover, IIEF-5 score was directly correlated with TT levels (r=0.67; p<.0001). CCI correlated with both TT levels and IIEF-5 score (r=-0.34 and -0.44; p<.0001, respectively). Finally, a lower IIEF-5 score was significantly and independently associated with higher age and CCI as well as lower TT and SHBG. Compared to the CCI, an equal performance was also found with the mCCI.Discussion. Our results showed that CCI and mCCI are reliable tools to assess the presence and severity of ED among outpatients referred to the endocrine center. However, some limitations should be considered, including the number of participants, which appeared underpowered; the single-center experience; possible underestimation of CCI referred to a diagnostic delay of included comorbidities; arbitrary assignment of burden-points to hypertension dyslipidemia and cigarette smoking.Conclusion. The present study found that CCI, a validated tool to assess the burden of comorbidities, correlates with both the prevalence and severity of ED. This confirms that ED is a reliable proxy of overall male health, but further studies are needed to confirm this potential application.

2017 ◽  
Vol 1 (3) ◽  
pp. 10-16
Author(s):  
Prakashkumar Kyada ◽  
Kunal Jadhav ◽  
T. K. Biswas ◽  
Varshil Mehta ◽  
Sojib Bin Zaman

Objective: Hypertension is one of the common risk factors for cardiovascular and cerebrovascular diseases/disorders A developing country like India faces the double burden of communicable and non-communicable diseases; of the which, hypertension is the most important treatable cause of mortality and morbidity with loss of functional capacity and decline in the quality of life. Aim: To study the prevalence of end organ damage in the hypertensive geriatric age group. Method: The present study was a cross sectional study, conducted in 150 elderly patients admitted in MGM Hospital, Navi Mumbai, India with the diagnosis of stage I or II hypertension from 2011 to 2013. Results: Data analysis of the present study showed that 68% of elderly population aged between 60 to 69 years were suffering from hypertension. Compared to males, females had a higher rate of target organ damage. This study found that out of all patients with total end organ damage, 54.6 % had CVS complications, 15.7 % had hypertensive retinopathy, 25.9 % and 18.51 had raised creatinine and proteinuria respectively. 19.4 % had cerebrovascular accident (CVA) complications. Among Cardiovascular related complications Coronary artery disease (CAD) was found in 21 patients, out of them 7 had Congestive cardiac Failure (CCF). Left Ventricular Hypertrophy (LVH) was the most common complication and seen in 38 patients. 13.8 % patients had Regional Wall Motion Abnormality (RWMA) Conclusion: The present study concluded that Isolated Systolic Hypertension (ISH) is the commonest type of hypertension in geriatric age group. This study concluded that the most common risk factors of HTN in the elderly are sedentary life style, dyslipidemia and extra salt intake while the most common end organ damage was observed to be Left Ventricular Hypertrophy followed by renal dysfunction. Keywords:  Hypertension,  Isolated Systolic Hypertension, Dyslipidemia.


2017 ◽  
Vol 17 (3) ◽  
pp. 86-96 ◽  
Author(s):  
Mohd Rohaizat Hassan ◽  
Mohd Fadhli Samsuri ◽  
Shamsul Azhar Shah ◽  
Nazarudin Safian ◽  
Zulkifli Md Zainuddin ◽  
...  

The purpose of this study was to determine the prevalence and factors associated with of Premature Ejaculation &Erectile Dysfunctionamong Malaysian men. A cross-sectional study was conducted in urban and rural areas using standardized and validated self-administered questionnaires. A total of 319 samples were recruited for PE screening. The overall prevalence of PE was 31.7% with 20.7% and 40.8% for urban and rural area respectively. Depression, anxiety and frequent masturbation were significantly associated with PE. While For ED, infrequent sexual intercourse was the sole factor significantly associated with ED.PE and ED were highly prevalent in both urban and rural areas; with several significant preventable associated factors.


Author(s):  
Roshina Sunny ◽  
Sitanshu Sekhar Kar ◽  
Dasari Papa ◽  
Sujiv Akkilagunta ◽  
Jeby Jose Olickal

Background: The high mortality among cervical cancer patients in India can be attributed to presentation at advanced stages. The varied and lengthy pathway taken up to diagnosis could be a major reason for advanced stage at presentation. Hence, we aimed to describe the care pathways and diagnostic delay among cervical cancer patients.Methods: A hospital-based cross-sectional study was conducted among 101 cervical cancer patients attending a cancer clinic at a Regional Cancer Center. The histo-pathologically confirmed cases of cervical cancer, who registered in July to October 2018 were approached. Data were collected through personal interviews using a semi-structured questionnaire. Descriptive statistics were used to describe the number of providers visited and diagnostic delay.Results: The median (range) number of providers visited by the patients up to diagnosis was 2 (1-5). As the first point of care, 14% of participants approached sub-center or primary care facilities, 27% approached secondary care facilities, 49% participants approached tertiary care facilities and 11% came directly to a regional cancer center. Diagnosis was made only in 24% of participants at secondary and tertiary care levels. The median (IQR) number of days to get diagnosed was 66 (30-130) days and three fourth of the patients had a diagnostic delay.Conclusions: The diagnostic delay was higher among patients who consulted multiple providers. Implementing a protocol to be followed at all three levels of health care delivery system may enhance the early diagnosis. 


2020 ◽  
Vol 6 (1) ◽  
pp. 184-189 ◽  
Author(s):  
Edoardo Pozzi ◽  
Paolo Capogrosso ◽  
Francesco Chierigo ◽  
Filippo Pederzoli ◽  
Eugenio Ventimiglia ◽  
...  

BMJ Open ◽  
2019 ◽  
Vol 9 (5) ◽  
pp. e023003 ◽  
Author(s):  
Yang Chen ◽  
Jie Li ◽  
Tianyu Li ◽  
Jianxiong Long ◽  
Jinling Liao ◽  
...  

ObjectivesErectile dysfunction (ED) affects up to 53.4% of men aged 30–80 years. In this study, we aimed to examine the association between homocysteine (HCY), vitamin B12(B12), folic acid (FA) and ED.DesignCross-sectional study.SettingGuangxi, China.ParticipantsA total of 1381 participants who completed questionnaires were included, between September 2009 and December 2009.MeasuresED was evaluated by the International Index of Erectile Function scores. Also, the values of HCY, B12 and FA were acquired. Then, regression and between-group analyses were performed.ResultsNo association between FA and ED was found. Significant correlations between HCY and ED were found—the relationships between these two parameters were most notable in men aged over 60 years and in men living alone (bachelors or bachelorhood). B12 levels were higher in men with ED (718.53±234.37 pg/mL vs 688.74±229.68, p=0.015). Using multinomial logistic regression analyses, B12 levels were related to mild ED (multivariate adjusted analysis: OR 1.620, 95% CI 1.141 to 2.300, p=0.007), especially among men aged 40–49 years (OR 2.907, 95% CI 1.402 to 6.026, p=0.004).ConclusionsWe report, for the first time, a relationship between B12 levels and ED. We also found specific cohorts of men for whom the relationship between HCY levels and ED is most prominent. Further studies are required to elucidate the mechanisms underlying these relationships—these may ultimately result in new therapies for ED.


2019 ◽  
Vol 18 (1) ◽  
Author(s):  
Anne Yee ◽  
Huai Seng Loh ◽  
Huai Heng Loh ◽  
Shahrzad Riahi ◽  
Chong Guan Ng ◽  
...  

Abstract Background Methadone is an effective therapy for opiate dependence. However, one of the commonest side effects is sexual dysfunction among male patients. Buprenorphine is an alternative to methadone. This study aimed to compare sexual desire among opiate-dependent male patients on buprenorphine (BMT) and methadone maintenance therapy (MMT). Methods This cross-sectional study involved 126 male opiate-dependent patient who were tested for total testosterone (TT) and prolactin levels, and were interviewed and completed the Sexual Desire Inventory-2 (SDI-2), Malay language of International Index of Erectile Function (Mal-IIEF-15) and the Malay version of the self-rated Montgomery-Asberg Depression Rating Scale (MADRS-BM) questionnaires. Results There were 95 (75.4%) patients on MMT and 31 (24.6%) on BMT. Patients on MMT scored significantly lower in the sexual desire domain (Mal-IIEF-15 scores) (p < 0.01), dyadic sexual desire (p = 0.04) and TT plasma level (p < 0.01) when compared to BMT group after controlling all the confounders. Conclusions Patients on MMT are associated with lower sexual desire when compared with patients on BMT. Smoking may further lower testosterone and, hence, sexual desire in those already on methadone.


Andrology ◽  
2020 ◽  
Author(s):  
Mehmet Yilmaz ◽  
Mustafa Karaaslan ◽  
Senol Tonyali ◽  
Mecit Celik ◽  
Tuncay Toprak ◽  
...  

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