Symptoms and lung function decline in a middle-aged cohort of males and females in Australia

Background: Given the documented importance of employment for middle-aged and older adults’ mental health, studies of the association between their number of work hours and depressive symptoms are needed. Objectives: To examine the association between the number of work hours and depressive symptoms in Korean aged 45 and over. Methods: We used data from the first wave to fourth wave of the Korea Longitudinal Study of Aging. Using the first wave at baseline, data included 9845 individuals. Depressive symptoms were measured using the 10-item Center for Epidemiological Studies Depression scale. We performed a longitudinal analysis to estimate the prevalence of depressive symptoms by work hours. Results: Both unemployed males and females aged 45–65 years were associated with higher depressive symptoms (β = 0.59, p < 0.001; β = 0.32, p < 0.001). Females working ≥ 69 h were associated with higher depressive symptoms compared to those working 41–68 h (β = 0.25, p = 0.013). Among those both middle-aged and older adults, both males and females unemployed were associated with higher depressive symptoms. Those middle-aged female working ≥69 h were associated with higher depressive symptoms. Conclusions: An increase in depressive symptoms was associated with unemployed males and females working ≥69 h compared to those working 41–68 h. Although this association was found among middle-aged individuals, a decrease in depressive symptoms in both sexes was associated with working 1–40 h. Depressive symptoms should decrease by implementing employment policies and social services to encourage employers to support middle-aged and older adults in the workforce considering their sex and age differences.

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Patterns of Unhealthy Eating Behaviours in a Middle Aged Scottish Population

Scottish Medical Journal ◽

10.1177/003693309203700604 ◽

1992 ◽

Vol 37 (6) ◽

pp. 170-174 ◽

Cited By ~ 6

Author(s):

T. Abel ◽

D.V. McQueen ◽

K Backen ◽

C. Currie

Keyword(s):

Alcohol Consumption ◽

Population Data ◽

Future Research ◽

Eating Behaviours ◽

Middle Aged ◽

Unhealthy Eating ◽

Scottish Population ◽

Males And Females ◽

Highly Correlated ◽

Nutrition Habits

This paper examines unhealthy eating in a middle aged Scottish population. Data from a 1989 survey of 5 00 Scottish men and women aged 45 to 59 years are used to explore inter-relations among five items of unhealthy eating, smoking and alcohol consumption. The results show that unhealthy eating behaviours are highly correlated, indicating strong links among certain nutrition habits. The findings also reveal that such patterns of unhealthy eating vary considerably between males and females. Finally, unhealthy eating behaviours were also found to be significantly associated with smoking and alcohol consumption. Implications of these findings for future research in epidemiology and health promotion are considered.

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RISK FACTORS OF INCREASING LUNG FUNCTION DECLINE IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE: A REAL-WORLD ANALYSIS

Respirology ◽

10.1111/resp.13207_425 ◽

2017 ◽

Vol 22 ◽

pp. 248-248

Keyword(s):

Risk Factors ◽

Chronic Obstructive Pulmonary Disease ◽

Lung Function ◽

Pulmonary Disease ◽

Real World ◽

Chronic Obstructive ◽

Lung Function Decline ◽

Obstructive Pulmonary Disease

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Can biomarkers of extracellular matrix remodelling and wound healing be used to identify high risk patients infected with SARS-CoV-2?: lessons learned from pulmonary fibrosis

Respiratory Research ◽

10.1186/s12931-020-01590-y ◽

2021 ◽

Vol 22 (1) ◽

Cited By ~ 2

Author(s):

D. J. Leeming ◽

F. Genovese ◽

J. M. B. Sand ◽

D. G. K. Rasmussen ◽

C. Christiansen ◽

...

Keyword(s):

Quality Of Life ◽

Extracellular Matrix ◽

Wound Healing ◽

Lung Function ◽

Pulmonary Fibrosis ◽

Interstitial Lung Diseases ◽

Lessons Learned ◽

Lung Function Decline ◽

Tissue Remodelling

AbstractPulmonary fibrosis has been identified as a main factor leading to pulmonary dysfunction and poor quality of life in post-recovery Severe Acute Respiratory Syndrome (SARS) survivor’s consequent to SARS-Cov-2 infection. Thus there is an urgent medical need for identification of readily available biomarkers that in patients with SARS-Cov-2 infection are able to; (1) identify patients in most need of medical care prior to admittance to an intensive care unit (ICU), and; (2) identify patients post-infection at risk of developing persistent fibrosis of lungs with subsequent impaired quality of life and increased morbidity and mortality. An intense amount of research have focused on wound healing and Extracellular Matrix (ECM) remodelling of the lungs related to lung function decline in pulmonary fibrosis (PF). A range of non-invasive serological biomarkers, reflecting tissue remodelling, and fibrosis have been shown to predict risk of acute exacerbations, lung function decline and mortality in PF and other interstitial lung diseases (Sand et al. in Respir Res 19:82, 2018). We suggest that lessons learned from such PF studies of the pathological processes leading to lung function decline could be used to better identify patients infected with SARS-Co-V2 at most risk of acute deterioration or persistent fibrotic damage of the lung and could consequently be used to guide treatment decisions.

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Atrial structure and function in middle‐aged, physically‐active males and females: A cardiac magnetic resonance study

Clinical Cardiology ◽

10.1002/clc.23707 ◽

2021 ◽

Author(s):

Meghan Glibbery ◽

Laura Banks ◽

Mustafa A. Altaha ◽

Robert F. Bentley ◽

Kaja Konieczny ◽

...

Keyword(s):

Cardiac Magnetic Resonance ◽

Magnetic Resonance ◽

Structure And Function ◽

Magnetic Resonance Study ◽

Middle Aged ◽

Physically Active ◽

Cardiac Magnetic Resonance Study ◽

Males And Females ◽

And Function

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Lung function decline is associated with serum uric acid in Korean health screening individuals

Scientific Reports ◽

10.1038/s41598-021-89678-3 ◽

2021 ◽

Vol 11 (1) ◽

Author(s):

Kyung-Min Ahn ◽

Suh-Young Lee ◽

So-Hee Lee ◽

Sun-Sin Kim ◽

Heung-Woo Park

Keyword(s):

Uric Acid ◽

Lung Function ◽

Serum Uric Acid ◽

Uric Acid Level ◽

Acid Level ◽

Serum Uric Acid Level ◽

Forced Expiratory Volume ◽

Linear Regression Models ◽

Lung Function Decline ◽

Health Screenings

AbstractWe performed a retrospective cohort study of 19,237 individuals who underwent at least three health screenings with follow-up periods of over 5 years to find a routinely checked serum marker that predicts lung function decline. Using linear regression models to analyze associations between the rate of decline in the forced expiratory volume in 1 s (FEV1) and the level of 10 serum markers (calcium, phosphorus, uric acid, total cholesterol, total protein, total bilirubin, alkaline phosphatase, aspartate aminotransferase, creatinine, and C-reactive protein) measured at two different times (at the first and third health screenings), we found that an increased uric acid level was significantly associated with an accelerated FEV1 decline (P = 0.0014 and P = 0.037, respectively) and reduced FEV1 predicted % (P = 0.0074 and P = 8.64 × 10–7, respectively) at both visits only in non-smoking individuals. In addition, we confirmed that accelerated forced vital capacity (FVC) and FEV1/FVC ratio declines were observed in non-smoking individuals with increased serum uric acid levels using linear mixed models. The serum uric acid level thus potentially predicts an acceleration in lung function decline in a non-smoking general population.

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