scholarly journals Chronic respiratory diseases and risk factors in 12 regions of the Russian Federation

Author(s):  
Alexander Chuchalin ◽  
Nikolai Khaltaev ◽  
Nikolay Antonov ◽  
Dmitry Galkin ◽  
Leonid Manakov ◽  
...  
Author(s):  
Леонид Манаков ◽  
Leonid Manakov ◽  
Виктор Колосов ◽  
Viktor Kolosov

There was done analysis of epidemiological monitoring of respiratory diseases (RD) on the territory of the Far Eastern Federal District (FEFD), which allows to assess the levels, structure and regional features of the spread of pathology among different populations and territorial formations, the dynamics of the disease and its relationship with the environmental factors of the region. To organize the study, the methods of cluster, structural and comparative analysis, predictive modeling, dynamic series analysis, statistical and information-analytical methods, databases of the Ministry of Health of the Russian Federation, the Federal State Statistics Service of the Russian Federation were used. The epidemiological analysis of the main indicators of RD level and dynamics in the FEFD territory indicates the presence of regional differences in the registered morbidity, the degree of which is due to the natural-climatic and socio-demographic characteristics of the habitat. 77.8% of the region's subjects are in the zone of low morbidity. At the same time, the values of maximum and minimum levels of general and primary RD morbidity in the region differ by 2.2 and 2.4 times, respectively, becoming the most pronounced among the adult population (by 3.6 times). In chronic bronchitis and COPD, the regional gradients of the registered morbidity are 10.9 and 9.8 times, respectively. It was found that the values of the primary RD morbidity in children's population in the FEFD are 14.4% higher than at the federal level, and among the adult population the gradient of values has the opposite indicators: 24.9% lower. At the same time, if the incidence of pneumonia in the region is 15.2% higher than the incidence of pneumonia in the Russian Federation as a whole, the incidence of chronic forms of RD in the region is 17.3-28.9% lower than at the federal level. The level of primary RD morbidity in 2005-2016 in the Far Eastern Federal District increased by 23.3%, including bronchial asthma (by 20.3%) and COPD (by 47.7%), and the incidence of pneumonia significantly decreased. At the same time, the average annual rate of increase in primary RD morbidity is higher than in the Russian Federation as a whole. This is shown by the predictive model of morbidity dynamics, the linear trends of which are more progressive in the FEFD compared to the dynamics at the federal level. The rate of positive dynamics of morbidity, significantly exceeding the same rate of morbidity growth at the federal level, indicates an increase in the level of availability and quality of medical care for patients with pulmonological profile, timely and early detection of chronic forms of respiratory diseases, positive motivation of the population for treatment in medical organizations. These trends in the dynamics of the registered morbidity are due to the active introduction of effective methods of diagnosis and treatment of chronic respiratory diseases, preventive and educational programs implemented both at the federal and regional level.


2021 ◽  
pp. 46-56
Author(s):  
Ivan Aleksandrovich Rybakov

In 2019 The Ministry of Health of the Russian Federation together with experts of the National Research Center of Therapy and Preventive Medicine of the Ministry of Health of the Russian Federation has developed programs to strengthen the health of employees, which include behavioral medicine practices aimed at changing lifestyle and correcting risk factors. Scientific evidence shows the effectiveness of such programs, and new components of programs aimed at improving the well-being of employees can increase the effectiveness of preventive measures. In this article, we will review the domestic and international experience of using comprehensive health and well-being promotion programs to improve the health of employees in Russia.


2020 ◽  
Vol 92 (1) ◽  
pp. 4-9 ◽  
Author(s):  
S A Boytsov ◽  
S A Shalnova ◽  
A D Deev

Chronic non - communicable diseases, mainly cardiovascular diseases, are the leading cause of death worldwide, including in the Russian Federation (RF). The article analyzes the negative and positive trends of the most relevant risk factors for cardiovascular diseases for the period from 2013 to 2017, and also provides a strategy for reducing mortality in the Russian Federation for the period up to 2024 based on data from an epidemiological analysis.


2019 ◽  
Vol 15 (5) ◽  
pp. 612-621
Author(s):  
S. A. Shalnova ◽  
M. V. Ezhov ◽  
V. A. Metelskaya ◽  
S. E. Evstifeeva ◽  
V. I. Tarasov ◽  
...  

Experimental and clinical data indicate a significant contribution of lipoprotein(a) (Lp[a]) to the atherogenesis. However, the pathophysiological mechanisms of this relationship are not fully understood.Aim. To investigate the distribution of Lp(a) in the population of the regions participating in the Study “Epidemiology of Cardiovascular Diseases in the Regions of the Russian Federation” (ESSE-RF) and to evaluate its associations with cardiovascular risk factors.Material and methods. Representative samples of the male and female population of 7 regions of the Russian Federation, aged from 25 to 64 years, enrolled in the multi-center cross-sectional epidemiological study were analyzed. A total of 10332 people were examined, of whom 3732 were men (36.0%) and 6600 were women (64.0%), the average age was equal in both sexes.Results. The mean value of Lp(a) reached 22.4 mg/dl (standard deviation 21.3 mg/dl) and significantly differed from the median (11.1 mg/dl; interquartile range from 3.9 to 20.2 mg/dl), forming the right-skewed distribution in both male and female population. Lp(a) levels were statistically significantly correlated with the level of low-density lipoproteins cholesterol (LDL-C), ароВ/аpoAI and total cholesterol. Notably, the odds ratios were growing by quintiles, and increased along with increasing lipid values (p<0.0001). Lp(a) levels were also positively associated with high-sensitivity C-reactive protein (hs-CRP) and negatively correlated with blood concentration of glucose and triglycerides (TG). There were no associations with body mass index, waist circumference and smoking status.Conclusion. According to the ESSE-RF data, there are significant positive associations of Lp(a) with the LDL-C level, the ароВ/аpoAI ratio, total cholesterol, and hs-CRP. Negative associations are established with glucose and TG levels. The future studies should be planned with the notion of the Lp(a)’s right-skewed distribution type. 


BMJ ◽  
2020 ◽  
pp. m234 ◽  
Author(s):  
Xiaochen Li ◽  
Xiaopei Cao ◽  
Mingzhou Guo ◽  
Min Xie ◽  
Xiansheng Liu

AbstractObjectiveTo describe the temporal and spatial trends of mortality and disability adjusted life years (DALYs) due to chronic respiratory diseases, by age and sex, across the world during 1990-2017 using data from the Global Burden of Disease Study 2017.DesignSystematic analysis.Data sourceThe Global Burden of Diseases, Injuries, and Risk Factors Study 2017.MethodsMortality and DALYs from chronic respiratory diseases were estimated from the Global Burden of Disease Study 2017 using DisMod-MR 2.1, a Bayesian meta-regression tool. The estimated annual percentage change of the age standardised mortality rate was calculated using a generalised linear model with a Gaussian distribution. Mortality and DALYs were stratified according to the Socio-demographic index. The strength and direction of the association between the Socio-demographic index and mortality rate were measured using the Spearman rank order correlation. Risk factors for chronic respiratory diseases were analysed from exposure data.ResultsBetween 1990 and 2017, the total number of deaths due to chronic respiratorydiseases increased by 18.0%, from 3.32 (95% uncertainty interval 3.01 to 3.43) million in 1990 to 3.91 (3.79 to 4.04) million in 2017. The age standardised mortality rate of chronic respiratory diseases decreased by an average of 2.41% (2.28% to 2.55%) annually. During the 27 years, the annual decline in mortality rates of chronic obstructive pulmonary disease (COPD; 2.36%, uncertainty interval 2.21% to 2.50%) and pneumoconiosis (2.56%, 2.44% to 2.68%) has been slow, whereas the mortality rate for interstitial lung disease and pulmonary sarcoidosis (0.97%, 0.92% to 1.03%) has increased. Reductions in DALYs for asthma and pneumoconiosis have been seen, but DALYs due to COPD, and interstitial lung disease and pulmonary sarcoidosis have increased. Mortality and the annual change in mortality rate due to chronic respiratory diseases varied considerably across 195 countries. Assessment of the factors responsible for regional variations in mortality and DALYs and the unequal distribution of improvements during the 27 years showed negative correlations between the Socio-demographic index and the mortality rates of COPD, pneumoconiosis, and asthma. Regions with a low Socio-demographic index had the highest mortality and DALYs. Smoking remained the major risk factor for mortality due to COPD and asthma. Pollution from particulate matter was the major contributor to deaths from COPD in regions with a low Socio-demographic index. Since 2013, a high body mass index has become the principal risk factor for asthma.ConclusionsRegions with a low Socio-demographic index had the greatest burden of disease. The estimated contribution of risk factors (such as smoking, environmental pollution, and a high body mass index) to mortality and DALYs supports the need for urgent efforts to reduce exposure to them.


2016 ◽  
Vol 19 (3) ◽  
pp. 19 ◽  
Author(s):  
V. G. Vilkov ◽  
S. A. Shalnova ◽  
A. O. Konradi ◽  
Yu. V. Zhernakova ◽  
S. A. Boytsov

2021 ◽  
Vol 31 (5) ◽  
pp. 551-561
Author(s):  
Elena V. Bystritskaya ◽  
Tatiana N. Bilichenko

Respiratory diseases (RD) represent one of the most urgent issues in Russian health care and have high socio-economic significance.The aim. To study the dynamics of total morbidity and mortality in the Russian Federation, as well as the mortality associated with RD in the working-age population in 2015 – 2019.Methods. The official statistical data of the Ministry of Health of the Russian Federation and the Federal State Statistics Service were analyzed.Results. In 2019, the total RD-associated morbidity increased by 5.4%, and the prevalence of pneumonia increased by 29.0% compared to 2015. In 5 federal districts (FD), the morbidity exceeded the average Russian morbidity in 2019 (40,694.7). The maximum level was observed in the North-Western FD (50,224.1). The prevalence of pneumonia (Russia – 524.4) in 4 FDs exceeded the average Russian prevalence. The maximum level was reported in the Far Eastern FD (749.2 cases per 100 thousand of the total population). The RD-associated mortality rate in Russia was 51.8 cases per 100 thousand in 2015 and 41.6 cases per 100 thousand in 2018 (–19.7%). In 2018, the highest RD-associated mortality was observed in the Siberian FD (68.0) and Far Eastern FD (57.8 per 100 thousand people). From January to December 2019, the highest mortality associated with pneumonia in the working-age population was observed in the Far Eastern FD (28.2 per 100 thousand people). The RD-associated mortality rate in the male population was 4.2 times higher than in the female population (26.7 and 6.3, respectively, per 100 thousand persons of matching age).Conclusion. The highest morbidity was found in 2018 and 2019 in the Northwestern FD and Far Eastern FD. The RD-associated mortality in the Siberian FD and Far Eastern FD exceeded the average Russian values. This last observation requires additional research to improve the quality of medical care.


4open ◽  
2019 ◽  
Vol 2 ◽  
pp. 23 ◽  
Author(s):  
Mariya Yurievna Pakharukova ◽  
José Manuel Correia da Costa ◽  
Viatcheslav Alekseevitch Mordvinov

Opisthorchiasis caused by the liver fluke Opisthorchis felineus is one of the most common helminthic infections in the Russian Federation. The largest area affected by opisthorchiasis felinea occupies almost the entire territory of Western Siberia and extends to northern Kazakhstan and a part of the Ural region. Natural endemic regions of opisthorchiasis also exist in the European part of Russia, and in the regions of Western and Eastern Europe. According to the official statistics of the Russian Federation, up to 40 000 patients with opisthorchiasis are registered annually in the country. Opisthorchiasis felinea affects the hepatobiliary system and causes serious liver disorders, including cancer of the biliary tract. Other parasitoses, opisthorchiasis viverrini and clonorchiasis, are widespread in the Southeast Asia and China. The causative agents of these diseases, liver flukes O. viverrini and Clonorchis sinensis, are officially recognized as Group 1 biological carcinogens and are classified as the main risk factors for cholangiocarcinoma. O. felineus is included in Group 3 of biological carcinogens and is not officially considered carcinogenic to humans. Studies on the carcinogenic potential of this liver fluke and the epidemiology of cholangiocarcinoma in the Russian Federation have started in earnest quite recently. Nevertheless, we have some evidence that infection with O. felineus leads to a precancerous state of the bile duct epithelium. This state, combined with additional risk factors, poses a real risk of cholangiocarcinoma. In our opinion, taking into consideration the accumulated facts, the classification of the carcinogenic potential of O. felineus requires revision. In this review, we focus on the relevant characteristics of the biology and epidemiology of this helminth as well as experimental data on opisthorchiasis felinea; this information might clarify the carcinogenicity of O. felineus to humans.


Sign in / Sign up

Export Citation Format

Share Document