Liposomes as Herbal Compounds Carrier: An update review

2021 ◽  
Vol 17 ◽  
Author(s):  
Mahshid Jahadi ◽  
Kourosh Keighobadi ◽  
Behnaz Azimzadeh ◽  
Hadiseh Keivani ◽  
Kianoush Khosravi-Darani
Keyword(s):  
Environmental Stress ◽  
Human Health ◽  
Google Scholar ◽  
Beneficial Effects ◽  
Liposome Preparation ◽  
Herbal Compound ◽  
Encapsulation Method ◽  
Web Of Knowledge ◽  
Potential Tool ◽  
Improve Stability

Background and Objective: Beneficial impacts of Phytochemicals on human health have attracted the interest of research more than ever. In this paper after a glance at the health beneficial impacts of the herbal compound, the obstacles of their usage in pharmaceutical and nutraceutical fields have been reported. Then encapsulation technique has been studied as a solution to overcome the limitations and finally, liposomes have been introduced as the carriers. Methods: Online papers were considered through various search websites, including PubMed, web of knowledge, Google Scholar, and Scopus from 2003 to 2020 to find reviews, editorials, and articles on the effects of herbal compounds on human health, improving the characteristics of phytocompounds by liposome and introduce heating methods of liposome preparation. Results: Herbal-derived compounds seem to be a potential tool for the prevention of disorders while they are susceptible to environmental stress. Encapsulation of herbal-derived compounds in liposomes and nanoliposomes is suggested to improve stability and bioavailability. Conclusion: This article reviewed the beneficial effects of liposomal as encapsulation method in improving sustainability and carrier of herbal-derived compounds for application in the pharmaceutical and nutraceutical industry.

Probiotic Microorganisms and Encapsulation Method Approaches

2018 ◽  
pp. 132-151
Author(s):  
Seydi Yıkmış ◽  
Harun Aksu ◽  
Mehmet Alpaslan ◽  
Osman Şimşek
Keyword(s):  
Shelf Life ◽  
Human Health ◽  
Food Processing ◽  
Healthy Life ◽  
Processing Technologies ◽  
Beneficial Effects ◽  
Encapsulation Method ◽  
And Storage ◽  
Encapsulation Methods ◽  
Milk And Dairy Products

Nowadays, interest in probiotics, which are useful and necessary for healthy life, is rapidly increasing, and studies on the beneficial effects of probiotics on human health continue intensely. Every year, increasing efforts to prevent cancer, which has been anticipated, has increased the interest in probiotics and therefore synbiotics. Encapsulation methods are one of the most important protection methods currently used to ensure the viability of probiotics and their effectiveness. Especially milk and dairy products are used for many purposes such as increasing the shelf life, increasing the nutritional value, providing digestibility, shortening the ripening period, improving taste and aroma substances. The use of the microencapsulation technique alone can improve probiotic vitality. Combining microencapsulation with various food processing technologies is thought to help improve the vitality of probiotics in production and storage. In this chapter, probiotic microorganisms and encapsulation applications are explored.

Effects of Minor Compounds of Edible Oils on Human Health

2020 ◽  
Vol 16 (8) ◽  
pp. 1196-1208
Author(s):  
Ramin Ghodsi ◽  
Rahmat Nosrati
Keyword(s):  
Human Health ◽  
Food Industry ◽  
Edible Oils ◽  
Food Groups ◽  
Bioactive Constituents ◽  
Beneficial Effects ◽  
Anti Cancer ◽  
Prevention And Treatment ◽  
Minor Compounds ◽  
Anti Inflammation

Background: Oils and fats are the densest sources of food energy among food groups. Vegetable oils are constituted predominantly of triglycerides. Due to the importance of edible oils in nutrition, food industry and human health, great attention has been paid to them in recent years. Some minor bioactive constituents in oils include phospholipids, tocols, sterols, carotenoid, chlorophyll, phenols, phylokynon and terpenes. Objective: The aim of the present study was to examine beneficial effects of minor compounds in edible oils on human health. Results: Minor compounds of edible oils that we use daily can produce remarkable results in the prevention and treatment of various diseases like diabetes, inflammation, hypertension, cancer, allergy and central nervous system disorders due to their antimicrobial, anti-cancer, anti-viral, anti-oxidative, anti-inflammation, anti-mutagenic, hypolipidemic, and hypoglycemic properties, among others. Conclusion: The results of this study showed that the presence of beneficial minor compounds in oils could have significant impact on the prevention and treatment of various diseases. Therefore, the type of consumed oil can play an important role in human health.

scholarly journals Pinus Species as Prospective Reserves of Bioactive Compounds with Potential Use in Functional Food—Current State of Knowledge

Plants ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1306
Author(s):  
Marcin Dziedziński ◽  
Joanna Kobus-Cisowska ◽  
Barbara Stachowiak
Keyword(s):  
Human Health ◽  
Bioactive Compounds ◽  
Functional Food ◽  
Biological Activities ◽  
Food Ingredients ◽  
Beneficial Effects ◽  
Pine Tree ◽  
Pine Trees ◽  
Health Promoting ◽  
Few Data

The pine (Pinus L.) is the largest and most heteromorphic plant genus of the pine family (Pinaceae Lindl.), which grows almost exclusively in the northern hemisphere. The demand for plant-based remedies, supplements and functional food is growing worldwide. Although pine-based products are widely available in many parts of the world, they are almost absent as food ingredients. The literature shows the beneficial effects of pine preparations on human health. Despite the wide geographical distribution of pine trees in the natural environment, there are very few data in the literature on the widespread use of pine in food technology. This study aims to present, characterise and evaluate the content of phytochemicals in pine trees, including shoots, bark and conifer needles, as well as to summarise the available data on their health-promoting and functional properties, and the potential of their use in food and the pharmaceutical industry to support health. Various species of pine tree contain different compositions of bioactive compounds. Regardless of the solvent, method, pine species and plant part used, all pine extracts contain a high number of polyphenols. Pine tree extracts exhibit several described biological activities that may be beneficial to human health. The available examples of the application of pine elements in food are promising. The reuse of residual pine elements is still limited compared to its potential. In this case, it is necessary to conduct more research to find and develop new products and applications of pine residues and by-products.

scholarly journals Methodologies in the Analysis of Phenolic Compounds in Roselle (Hibiscus sabdariffa L.): Composition, Biological Activity, and Beneficial Effects on Human Health

Horticulturae ◽  
2021 ◽  
Vol 7 (2) ◽  
pp. 35
Author(s):  
Bety W. Hapsari ◽  
Manikharda ◽  
Widiastuti Setyaningsih
Keyword(s):  
Biological Activity ◽  
Phenolic Compounds ◽  
Human Health ◽  
Analytical Methods ◽  
Environmental Influence ◽  
Biological Activities ◽  
Research Progress ◽  
Hibiscus Sabdariffa ◽  
Beneficial Effects ◽  
Positive Effects

Roselle (Hibiscus sabdariffa L.), as an edible flower, has long provided an array of positive effects on human health. This benefit is a result of phenolic compounds that are naturally present mainly in the calyx. Plentiful medicinal remedies and functional foods based on this flower are available worldwide, as supported by the studies of phenolic compounds in recent decades. This paper aims to provide a comprehensive review of the composition, biological activity, and beneficial effects on human health of phenolic compounds in roselle. This review was performed in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. A structured search in the published literature for phenolics compositions in roselle was required prior to the evaluation on the validity of the reported analytical methods. Reliable identification and quantification of phenolic compounds in roselle can be achieved by employing the proper extraction and separation methods. With ample alternative analytical methods discussed here, this review provided an aid for comprehending and selecting the most appropriate method for a particular study. The applications of the analytical methods highlighted indicated that phenolic acids, flavonoids, and their derivatives have been identified and quantified in roselle with a range of biological activities and beneficial effects on human health. It was also disclosed that the composition and concentration of phenolic compounds in roselle vary due to the growth factors, cultivars, and environmental influence. Finally, apart from the research progress carried out with roselle during the last ten years, this review also proposed relevant future works.

scholarly journals Bioactive effects of citrus flavonoids and role in the prevention of atherosclerosis and cancer

2022 ◽  
Author(s):  
Marco Giammanco ◽  
Fulvio Plescia ◽  
Manfredi M. Giammanco ◽  
Gaetano Leto ◽  
Carla Gentile
Keyword(s):  
Human Health ◽  
Observational Studies ◽  
Degenerative Diseases ◽  
Malignant Diseases ◽  
Citrus Fruits ◽  
Beneficial Effects ◽  
Pathological Conditions ◽  
Citrus Flavonoids ◽  
Prevention Of Atherosclerosis ◽  
Reduced Risk

Citrus fruits are the main fruits of the Mediterranean diet and have been long recognized for their beneficial effects on human health. Observational studies have shown a significant association between dietary flavo-noid intake and reduced risk of cardiovascular and malignant diseases. The beneficial effects of citrus fruits on human health appear to be due to their high content in vitamins, minerals and fibers. In particular, the an-tioxidant and anti-inflammatory activities have been indicated as some of the mechanisms through which citrus fruits may thwarts the development of chronic degenerative diseases such as atherosclerosis and can-cer. This review would critically examine the results from numerous studies carried out in order assess the contribute of citrus flavonoids to the prevention of chronic pathological conditions including athero-sclerosis and cancer.

scholarly journals Probiotics as Human Health Promoters

2018 ◽  
Vol 9 (2) ◽  
pp. 102-105
Author(s):  
Shiekh Ajaz Rasool ◽  
Fehmida Mirza ◽  
Hera Waheed ◽  
Muhammad Munir
Keyword(s):  
Human Health ◽  
Proteolytic Enzymes ◽  
Streptococcus Thermophilus ◽  
Well Being ◽  
Micro Rna ◽  
Signal Pathways ◽  
Beneficial Effects ◽  
Probiotic Strains ◽  
H Pylori ◽  
Microbial Groups

Probiotics (Pro-life live entities) provide the health and well being with multitude of beneficial effects on humans and animals (and relief against varied disorders). Probiotics may manage lactose intolerance, elevate immune profile, prevent colorectal cancers, reduce cholesterol and triglyceride profile, lowering blood pressure and inflammatory process. They also prevent osteoporosis, allergic reactions and help suppress H. pylori infections and other pathological manifestations. Microbial metabolites (even in the absence of live entities) may exert (analogous) effects on signal pathways and barrier functions. Such substances are referred as ‘Postbiotics’ (the plain metabolic byproduct of probiotics, bioactive manifestations in the host). Generally, postbiotics include secondary metabolites such as bacteriocins, organic acids, ethanol, acetaldehyde, reactive oxygen species (ROS). Such metabolites are inhibitory against pathogenic strains of different broad spectrum drug resistant microbial groups (MDR, XDR etc). Postbiotics are safe, apathogenic which may resist hydrolysis by enzymes of mammalian origin. It has been described that micro-RNA profile of human milk may exert the inhibitory effects of probiotics. Our research group has been investigating the merits of mammalian milk as a viable source of probiotics that secrete bioactive peptides against MDR/biofilm producing strains (ref. Streptococcus thermophilus and Enterococcus faecalis, a GIT probiont). These peptides are in the range of 10-16KDa molecular mass (sensitive to proteolytic enzymes as well). Genes coding for these peptides are plasmid associated. Mode of action of these peptides is bacteriostatic. Molecular identification of these Probiotic strains is being followed. This, on the whole marks an emphasis on biological operation of novel strains of Probiotic and their applications in medico-clinical areas to improve the human health and wellness.

scholarly journals Omega-3 Polyunsaturated Fatty Acids Inhibit the Function of Human URAT1, a Renal Urate Re-Absorber

Nutrients ◽  
2020 ◽  
Vol 12 (6) ◽  
pp. 1601 ◽  
Author(s):  
Hiroki Saito ◽  
Yu Toyoda ◽  
Tappei Takada ◽  
Hiroshi Hirata ◽  
Ami Ota-Kontani ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Human Health ◽  
Serum Urate ◽  
The Body ◽  
Omega 3 ◽  
Beneficial Effects ◽  
Uricosuric Agents ◽  
Transport Assay ◽  
The Impact

The beneficial effects of fatty acids (FAs) on human health have attracted widespread interest. However, little is known about the impact of FAs on the handling of urate, the end-product of human purine metabolism, in the body. Increased serum urate levels occur in hyperuricemia, a disease that can lead to gout. In humans, urate filtered by the glomerulus of the kidney is majorly re-absorbed from primary urine into the blood via the urate transporter 1 (URAT1)-mediated pathway. URAT1 inhibition, thus, contributes to decreasing serum urate concentration by increasing net renal urate excretion. Here, we investigated the URAT1-inhibitory effects of 25 FAs that are commonly contained in foods or produced in the body. For this purpose, we conducted an in vitro transport assay using cells transiently expressing URAT1. Our results showed that unsaturated FAs, especially long-chain unsaturated FAs, inhibited URAT1 more strongly than saturated FAs. Among the tested unsaturated FAs, eicosapentaenoic acid, α-linolenic acid, and docosahexaenoic acid exhibited substantial URAT1-inhibitory activities, with half maximal inhibitory concentration values of 6.0, 14.2, and 15.2 μM, respectively. Although further studies are required to investigate whether the ω-3 polyunsaturated FAs can be employed as uricosuric agents, our findings further confirm FAs as nutritionally important substances influencing human health.

Microbiote et probiotiques : impact en santé humaine

2010 ◽  
Vol 56 (8) ◽  
pp. 611-650 ◽  
Author(s):  
Sophie Coudeyras ◽  
Christiane Forestier
Keyword(s):  
Lactic Acid ◽  
Human Health ◽  
Health Benefit ◽  
Therapeutic Strategies ◽  
Beneficial Effects ◽  
Mucous Membranes ◽  
Genus Lactobacillus ◽  
Human Flora ◽  
Constant Improvement

All accessible mucous membranes of the human body are colonized by an abundant and diversified microbial flora called microbiota. Recent studies have shown that these microorganisms, long regarded as purely commensal, have essential beneficial effects on human health. Thus, numerous human ailments are linked to dysbiosis; that is, imbalances in the microflora composition. The administration of probiotic microorganisms could, in some situations, provide substantial relief from such disorders. These live microorganisms, which, according to the definition, confer a health benefit to the host when administered in adequate amounts, are often derived from human flora and belong mostly to lactic acid bacteria, in particular to the genus Lactobacillus . The constant improvement of knowledge of the role of human microbiota and the growing popularity of probiotics are now opening the door to new prophylactic and therapeutic strategies in human health.

scholarly journals Probiotics: Versatile Bioactive Components in Promoting Human Health

Medicina ◽  
2020 ◽  
Vol 56 (9) ◽  
pp. 433 ◽  
Author(s):  
Javad Sharifi-Rad ◽  
Célia F. Rodrigues ◽  
Zorica Stojanović-Radić ◽  
Marina Dimitrijević ◽  
Ana Aleksić ◽  
...  
Keyword(s):  
Human Health ◽  
Positive Impact ◽  
Intestinal Flora ◽  
Pharmaceutical Products ◽  
Beneficial Effects ◽  
Food And Nutrition ◽  
Post Market ◽  
Health Care Applications ◽  
Probiotic Strains ◽  
And Control

The positive impact of probiotic strains on human health has become more evident than ever before. Often delivered through food, dietary products, supplements, and drugs, different legislations for safety and efficacy issues have been prepared. Furthermore, regulatory agencies have addressed various approaches toward these products, whether they authorize claims mentioning a disease’s diagnosis, prevention, or treatment. Due to the diversity of bacteria and yeast strains, strict approaches have been designed to assess for side effects and post-market surveillance. One of the most essential delivery systems of probiotics is within food, due to the great beneficial health effects of this system compared to pharmaceutical products and also due to the increasing importance of food and nutrition. Modern lifestyle or various diseases lead to an imbalance of the intestinal flora. Nonetheless, as the amount of probiotic use needs accurate calculations, different factors should also be taken into consideration. One of the novelties of this review is the presentation of the beneficial effects of the administration of probiotics as a potential adjuvant therapy in COVID-19. Thus, this paper provides an integrative overview of different aspects of probiotics, from human health care applications to safety, quality, and control.

Finishing diets used in beef and lamb production in Northern Ireland: results of a questionnaire survey

2009 ◽  
Vol 2009 ◽  
pp. 137-137
Author(s):  
A J McAfee ◽  
E Duffy ◽  
G Cuskelly ◽  
A Fearon ◽  
J Wallace ◽  
...  
Keyword(s):  
Fatty Acid ◽  
Northern Ireland ◽  
Human Health ◽  
Polyunsaturated Fatty Acid ◽  
Strong Evidence ◽  
Questionnaire Survey ◽  
Pufa Content ◽  
Finishing Diets ◽  
Beneficial Effects ◽  
Feeding Regimes

Ruminant feeding regimes that include grass finishing are known to increase the n-3 polyunsaturated fatty acid (n-3 PUFA) content of beef and lamb. By contrast, concentrate finishing produces meat with increased n-6 PUFA concentrations. There is strong evidence that increasing the ratio of n-3: n-6 PUFA in the diet has beneficial effects for human health. In Northern Ireland, it is likely that feeding regimes are predominantly grass-based; therefore beef and lamb could contain appreciable amounts of n-3 PUFA. However, an analysis of types of finishing diets used by farms in Northern Ireland has not been done. The aim of this study was to assess the frequency of grass and concentrate finishing in farms in Northern Ireland.

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