scholarly journals Methodologies in the Analysis of Phenolic Compounds in Roselle (Hibiscus sabdariffa L.): Composition, Biological Activity, and Beneficial Effects on Human Health

Horticulturae ◽  
2021 ◽  
Vol 7 (2) ◽  
pp. 35
Author(s):  
Bety W. Hapsari ◽  
Manikharda ◽  
Widiastuti Setyaningsih
Keyword(s):  
Biological Activity ◽  
Phenolic Compounds ◽  
Human Health ◽  
Analytical Methods ◽  
Environmental Influence ◽  
Biological Activities ◽  
Research Progress ◽  
Hibiscus Sabdariffa ◽  
Beneficial Effects ◽  
Positive Effects

Roselle (Hibiscus sabdariffa L.), as an edible flower, has long provided an array of positive effects on human health. This benefit is a result of phenolic compounds that are naturally present mainly in the calyx. Plentiful medicinal remedies and functional foods based on this flower are available worldwide, as supported by the studies of phenolic compounds in recent decades. This paper aims to provide a comprehensive review of the composition, biological activity, and beneficial effects on human health of phenolic compounds in roselle. This review was performed in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. A structured search in the published literature for phenolics compositions in roselle was required prior to the evaluation on the validity of the reported analytical methods. Reliable identification and quantification of phenolic compounds in roselle can be achieved by employing the proper extraction and separation methods. With ample alternative analytical methods discussed here, this review provided an aid for comprehending and selecting the most appropriate method for a particular study. The applications of the analytical methods highlighted indicated that phenolic acids, flavonoids, and their derivatives have been identified and quantified in roselle with a range of biological activities and beneficial effects on human health. It was also disclosed that the composition and concentration of phenolic compounds in roselle vary due to the growth factors, cultivars, and environmental influence. Finally, apart from the research progress carried out with roselle during the last ten years, this review also proposed relevant future works.

Cannabis Phenolics and their Bioactivities

2018 ◽  
Vol 25 (10) ◽  
pp. 1160-1185 ◽  
Author(s):  
Federica Pollastro ◽  
Alberto Minassi ◽  
Luigia Grazia Fresu
Keyword(s):  
Biological Activity ◽  
Phenolic Compounds ◽  
Cannabis Sativa ◽  
Biological Activities ◽  
Bibliographic Databases ◽  
Systematic Research ◽  
Prenylated Flavonoids ◽  
Beneficial Effects ◽  
Almost All

Background: Although Cannabis sativa L. is one of the most versatile plant species with multipurpose use both as medical, alimentary source and as psychoactive abuse, its biomedical relevance focused the attention on major cannabinoids. Phytochemical characterization of cannabis highlights the presence of various non-cannabinoids constituents including flavonoids, spiroindans, dihyrostilbenes, dihydrophenanthrenes, lignanamides, steroids and alkaloids. This review aims to identify polyphenols present in this plant, their biosynthesis, their bioactivities and their synthesis, when this occurred. Methods: We undertook a systematic research focused on bibliographic databases including all noncannabinoids phenolics in various C. sativa strains from their isolation, structural elucidation, their biological activity to their synthesis. Result: Nevertheless, attention has so far been focused only on cannabinoids (more than one hundred isolated), cannabis is a complex plant able to produce more than 480 chemical entities that represent almost all of the different biogenetic classes. Regarding phenolic compounds, the plant biosynthesises a plethora of unique non-cannabinoids second metabolites, such as prenylated flavonoids, stilbenoids derivatives and lignanammides. Conclusion: Cannabis is a plant with high pharmacological and nutrition values, its potentialities and applications are not only circumscribed to cannabinoids biological activities, but also defined by noncannabinoid compounds. The combination of other cannabinoids together with noncannabinoid components could enhance the beneficial effects of THC and could reduce undesirable side effects.

scholarly journals Honey as a Complementary Medicine

2017 ◽  
Vol 12 ◽  
pp. 117863371770286 ◽  
Author(s):  
MG Miguel ◽  
MD Antunes ◽  
ML Faleiro
Keyword(s):  
Biological Activity ◽  
Antiviral Activity ◽  
Alternative Medicine ◽  
Human Health ◽  
Mode Of Action ◽  
Geographic Origin ◽  
Human Pathogen ◽  
Beneficial Effects ◽  
Positive Effects ◽  
Pathogen Control

The beneficial effects of honey on human health have long been recognized. Today, many of those positive effects have been studied to elucidate its mode of action. This review briefly summarizes the best studied features of honey, highlighting it as an appealing alternative medicine. In these reports, the health benefits of honey range from antioxidant, immunomodulatory, and anti-inflammatory activity to anticancer action, metabolic and cardiovascular benefits, prebiotic properties, human pathogen control, and antiviral activity. These studies also support that the honey’s biological activity is mainly dependent on its floral or geographic origin. In addition, some promising synergies between honey and antibiotics have been found, as well as some antiviral properties that require further investigation. Altogether, these studies show that honey is effectively a nutraceutical foodstuff.

scholarly journals Bioactivity, Health Benefits, and Related Molecular Mechanisms of Curcumin: Current Progress, Challenges, and Perspectives

Nutrients ◽  
2018 ◽  
Vol 10 (10) ◽  
pp. 1553 ◽  
Author(s):  
Xiao-Yu Xu ◽  
Xiao Meng ◽  
Sha Li ◽  
Ren-You Gan ◽  
Ya Li ◽  
...  
Keyword(s):  
Human Health ◽  
Molecular Mechanisms ◽  
Protective Efficacy ◽  
Biological Activities ◽  
Curcuma Longa ◽  
Health Benefits ◽  
Research Progress ◽  
Beneficial Effects ◽  
Preventive Effects ◽  
Gut Metabolism

Curcumin is a principal curcuminoid of turmeric (Curcuma longa), which is commonly used as a spice in cooking and a yellow pigment in the food processing industry. Recent studies have demonstrated that curcumin has a variety of biological activities and pharmacological performances, providing protection and promotion of human health. In addition to presenting an overview of the gut metabolism of curcumin, this paper reviews the current research progress on its versatile bioactivity, such as antioxidant, anti-inflammatory, and immune-regulatory activities, and also intensively discusses its health benefits, including the protective or preventive effects on cancers and diabetes, as well as the liver, nervous system, and cardiovascular systems, highlighting the potential molecular mechanisms. Besides, the beneficial effects of curcumin on human are further stated based on clinical trials. Considering that there is still a debate on the beneficial effects of curcumin, we also discuss related challenges and prospects. Overall, curcumin is a promising ingredient of novel functional foods, with protective efficacy in preventing certain diseases. We hope this comprehensive and updated review will be helpful for promoting human-based studies to facilitate its use in human health and diseases in the future.

scholarly journals Pinus Species as Prospective Reserves of Bioactive Compounds with Potential Use in Functional Food—Current State of Knowledge

Plants ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1306
Author(s):  
Marcin Dziedziński ◽  
Joanna Kobus-Cisowska ◽  
Barbara Stachowiak
Keyword(s):  
Human Health ◽  
Bioactive Compounds ◽  
Functional Food ◽  
Biological Activities ◽  
Food Ingredients ◽  
Beneficial Effects ◽  
Pine Tree ◽  
Pine Trees ◽  
Health Promoting ◽  
Few Data

The pine (Pinus L.) is the largest and most heteromorphic plant genus of the pine family (Pinaceae Lindl.), which grows almost exclusively in the northern hemisphere. The demand for plant-based remedies, supplements and functional food is growing worldwide. Although pine-based products are widely available in many parts of the world, they are almost absent as food ingredients. The literature shows the beneficial effects of pine preparations on human health. Despite the wide geographical distribution of pine trees in the natural environment, there are very few data in the literature on the widespread use of pine in food technology. This study aims to present, characterise and evaluate the content of phytochemicals in pine trees, including shoots, bark and conifer needles, as well as to summarise the available data on their health-promoting and functional properties, and the potential of their use in food and the pharmaceutical industry to support health. Various species of pine tree contain different compositions of bioactive compounds. Regardless of the solvent, method, pine species and plant part used, all pine extracts contain a high number of polyphenols. Pine tree extracts exhibit several described biological activities that may be beneficial to human health. The available examples of the application of pine elements in food are promising. The reuse of residual pine elements is still limited compared to its potential. In this case, it is necessary to conduct more research to find and develop new products and applications of pine residues and by-products.

scholarly journals Strawberry and Achenes Hydroalcoholic Extracts and Their Digested Fractions Efficiently Counteract the AAPH-Induced Oxidative Damage in HepG2 Cells

2018 ◽  
Vol 19 (8) ◽  
pp. 2180 ◽  
Author(s):  
María Ariza ◽  
Tamara Forbes-Hernández ◽  
Patricia Reboredo-Rodríguez ◽  
Sadia Afrin ◽  
Massimiliano Gasparrini ◽  
...  
Keyword(s):  
Biological Activity ◽  
Oxidative Damage ◽  
Hepg2 Cells ◽  
In Vitro Digestion ◽  
Protective Effects ◽  
Beneficial Effects ◽  
Positive Effects ◽  
Digestion Process ◽  
Phytochemical Compounds

Strawberry fruits are highly appreciated by consumers worldwide due to their bright red color, typical aroma, and juicy texture. While the biological activity of the complete fruit has been widely studied, the potential beneficial effects of the achenes (commonly named seeds) remain unknown. In addition, when raw fruit and achenes are consumed, the digestion process could alter the release and absorption of their phytochemical compounds, compromising their bioactivity. In the present work, we evaluated the protective effects against oxidative damage of nondigested and digested extracts from strawberry fruit and achenes in human hepatocellular carcinoma (HepG2) cells. For that purpose, cells were treated with different concentration of the extracts prior to incubation with the stressor agent, AAPH (2,2′-azobis(2-amidinopropane) dihydrochloride). Subsequently, intracellular accumulation of reactive oxygen species (ROS) and the percentage of live, dead, and apoptotic cells were determined. Our results demonstrated that all the evaluated fractions were able to counteract the AAPH-induced damage, suggesting that the achenes also present biological activity. The positive effects of both the raw fruit and achenes were maintained after the in vitro digestion process.

scholarly journals Antioxidant and anti-inflammatory activities of winery wastes seeds of Vitis labrusca

2011 ◽  
Vol 41 (7) ◽  
pp. 1233-1238 ◽  
Author(s):  
Gustavo Scola ◽  
Virginia Demarchi Kappel ◽  
José Claudio Fonseca Moreira ◽  
Felipe Dal-Pizzol ◽  
Mirian Salvador
Keyword(s):  
Phenolic Compounds ◽  
Phenolic Content ◽  
Biological Activities ◽  
Total Phenolic ◽  
Vitis Labrusca ◽  
Grape Seeds ◽  
Wine Production ◽  
Beneficial Effects ◽  
Environmental Balance ◽  
Anti Inflammatory

There are many studies about the biological activities of Vitis vinifera grape seeds, which are rich in phenolic compounds, known by their several health beneficial effects. However, until now there is no data about biological activities of the seeds of V. labrusca, specie found in South and North America. Every year, the global wine production (around 260 million hL) generates about 19.5 million ton of wastes, which are usually discarded in the environment. The aim of this research was to evaluate the antioxidant and anti-inflammatory activities of aqueous extracts of seeds from wine wastes of Vitis labrusca (cv. 'Bordo' and 'Isabella'). Both extracts showed significant antioxidant and anti-inflammatory activities, which are positively correlated with total phenolic content, suggesting that these compounds might be the major contributors to the biological activity of these extracts. These results indicate that water extraction from winery wastes is an option to obtain phenolic compounds with antioxidant and anti-inflammatory activities helping to maintain environmental balance.

scholarly journals Using the Eurotium cristatum Fungus for Preparing Fermented Herbal Teas -

2020 ◽  
Vol 10 (6) ◽  
pp. 341-361
Author(s):  
Elena F. Shanenko ◽  
Olga V. Efremenkova ◽  
Tatiana G. Mukhamedzanova ◽  
Yu. A. Nikolaev ◽  
Tatiana A. Efimenko ◽  
...  
Keyword(s):  
Amino Acids ◽  
Molecular Weight ◽  
Biological Activity ◽  
Phenolic Compounds ◽  
New Technologies ◽  
Biological Activities ◽  
Resistant Bacteria ◽  
Low Molecular Weight ◽  
High Biological Activity ◽  
Apple Leaves

Background: The biological activities of dark Chinese teas are largely due to their microbial post-fermentation. Herbal teas are traditional Russian beverages that hold special value, owing to their taste and useful medicinal properties. However, no data are available in the literature on using microbial post-fermentation for enhancing their biological activity. The goal of this work was to demonstrate that the fungus Eurotium isolated from Chinese black teas can be used for the post-fermentation of herbal teas produced from bay willow and apple leaves.Methods: Eurotium cristatum was isolated from brick Chinese tea Fujan and identified using conventional methods of microbiology and molecular biology. Low molecular weight metabolites (phenols, amines, sugars, and amino acids) were determined by HPLC. E. cristatum was grown in association with the bacterium Bacillus amyloliquefaciens.Results: It was revealed to exhibit valuable biosynthetic features, such as a lack of mycotoxins, zero antimicrobial activity, and the capacity to synthesize neuroactive amines. B. amyloliquefaciens displayed a wide spectrum of antibiotic (antimicrobial and antifungal) activities that anifested themselves even with antibiotic-resistant bacteria). While growing on green unfermented tea (Camellia sp.) E. cristatum produced and modified neuroactive amines, such as dopamine, serotonin, and epinephrine. The fungus efficiently grew during the post-fermentation of herbal teas from both bay willow and apple leaves. Even though Camellia leaves substantially differed from bay willow and apple leaves in terms of phenol content, the growth of E. cristatum on Camellia was also sufficiently good. This suggests that the growth of Eurotium fungi is not influenced by the phenolic compounds. The data obtained on the composition of phenolic compounds, carbohydrates, and amino acids in the fermented plants and raw material provide evidence that the growth of the fungus proceeds depends on the hydrolysis of high molecular weight phenols and cell biopolymers in the fermented material.Conclusion: Thus, the ability of E. cristatum to grow on plant leaves of significantly different biochemical composition provides foundations for new technologies aiming to obtain post-fermented herbal teas with high biological activity that are enriched in low molecular weight compounds including biogenic amines.

scholarly journals A review of current analytical methods for the determination of prebiotics in foods

2021 ◽  
Vol 4 (2) ◽  
pp. 146-159
Author(s):  
Son Tran Hung ◽  
Thanh An Vu Thi ◽  
Thanh Hoa Mac Thi ◽  
Khanh Cao Cong ◽  
Hong Hao Le Thi ◽  
...  
Keyword(s):  
Human Health ◽  
Intestinal Microbiota ◽  
Analytical Methods ◽  
Food Products ◽  
Food Samples ◽  
Beneficial Effects ◽  
Human Intestinal Microbiota ◽  
Good Potential ◽  
The Relationship

Prebiotics are a group that improves the human intestinal microbiota. The relationship between prebiotics and human health has been an area of increasing interest in recent years. Fructo-oligosaccharides and galacto-oligosaccharides are the two important groups of prebiotics with beneficial effects on human health. Besides that, more and more carbohydrates have shown a good potential to be prebiotics has been studied. This study presents a review of the characteristics, properties, and analytical methods used for the determination of prebiotics in food products. Most of the methods found using chromatographic methods, especially HPAEC - PAD but also another method, such as spectrometric methods have been presented. A discussion was presented highlighting the drawbacks of current analytical methods and the need to develop these methods to analyze the complex food samples containing prebiotics.

scholarly journals Advances in the Extraction, Purification, Structural Characteristics and Biological Activities of Eleutherococcus senticosus Polysaccharides: A Promising Medicinal and Edible Resource With Development Value

2021 ◽  
Vol 12 ◽  
Author(s):  
Xiaojie Li ◽  
Cai Chen ◽  
Aijing Leng ◽  
Jialin Qu
Keyword(s):  
Biological Activity ◽  
Structural Characterization ◽  
Biological Activities ◽  
Structural Characteristics ◽  
Research Progress ◽  
Eleutherococcus Senticosus ◽  
Radiation Enhancement ◽  
Extraction Separation ◽  
Development And Utilization ◽  
Efficient Extraction

In recent years, natural polysaccharides have received growing attention and interest in view of their values in food, medical, cosmetics and other fields. Eleutherococcus senticosus (E. senticosus) is a medicine and food homologous plant that possess anti-tumor, anti-inflammatory, central nervous system and cardiovascular protection, anti-radiation, enhancement of human microcirculation, improvement of physical fatigue effects, mainly based on lignans, flavonoids and coumarin types. E. senticosus polysaccharides (ESPS), act as a kind of polysaccharide extracted and isolated from the root and rhizome of E. senticosus, have been found in many applications of medicine and food for their unique biological activity. Nevertheless, the existing studies are mostly concerned with small molecules of E. senticosus, less attention is paid to polysaccharides. Moreover, the types and structural characterization of ESPS reported in existing literature were also not summarized. In this paper, the research progress of ESPS is reviewed from the aspects of extraction, separation, structural characterization and biological activity, future perspectives from points of efficient extraction, resource utilization and quality control standards were also proposed, which provide reference for the further development and utilization of ESPS.

scholarly journals Emerging source of bioactive compounds from Arecaceae family: a systematic review

2021 ◽  
Vol 10 (10) ◽  
pp. e426101018994
Author(s):  
Ricardo Sérgio da Silva ◽  
Paulo Henrique Oliveira de Miranda ◽  
Luciclaudio Cassimiro de Amorim ◽  
Paulo Henrique Eloi Fernandes ◽  
Elias Vinícius Ferreira do Amaral ◽  
...  
Keyword(s):  
Systematic Review ◽  
Fatty Acids ◽  
Phenolic Compounds ◽  
Human Health ◽  
Traditional Knowledge ◽  
Lauric Acid ◽  
Biological Activities ◽  
Biological Properties ◽  
The Family ◽  
Comprehensive Search

The use of plants for medicinal purposes is performed empirically by traditional knowledge with the use of preparations that seek to extract their active principles, and are considered to be fundamental to human health. In this context, the aim of the present study was to of this study was to carry out a systematic review of the biological activities of the Arecaceae family distributed throughout Brazil. This research was carried out through a comprehensive search using the following databases, Scopus, Portal Periódicos Capes, PubMed, Google Scholar and Science Direct, using the following descriptors: “Arecaceae” and “Biological properties of the family Arecaeae”, checked at <www.theplantlist.org/> to check synonyms. It was possible to identify numerous biological activities in the arecaceae family, among the most recurring ones, the antioxidant, antimicrobial and anti-inflammatory activity. These activities are justified by the presence of fatty acids, phenolic compounds, alkaloids and terpenes. Studies routinely report lauric acid as a major in the plants of this family, which makes it a potential compound to cure or assist in the treatment of various diseases.

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