Nickel and Skin: From Allergy to Autoimmunity

2020 ◽  
Vol 20 (7) ◽  
pp. 1032-1040
Author(s):  
Kossara Drenovska ◽  
Martin Shahid ◽  
Snejina Vassileva
Keyword(s):  
Scientific Literature ◽  
Internal Exposure ◽  
Present Moment ◽  
Review Of The Literature ◽  
Autoinflammatory Disorders ◽  
Metal Implants ◽  
Systemic Reactions ◽  
Nickel Compounds ◽  
Immunological Effects ◽  
Detailed Search

Introduction & Objectives: Cutaneous and systemic reactions to various metal implants and medical devices have been well documented. The aim of this review was to focus on the probable common mechanisms of allergy and autoimmunity that may lead to similar clinical outcomes following the growing evidence in the literature of metal and nickel-related systemic, autoimmune or autoinflammatory disorders. Methods: Detailed search of the available electronic databases (PubMed-Medline) was conducted for review of the literature on that topic till the present moment. Results: Multiple reports on the immunological effects of metals including immunomodulation, allergy, or autoimmunity were identified. It was found that metals may act through immunosuppression, immunotoxicity, or as immune adjuvants thus provoking allergy and autoimmunity in susceptible individuals. Both external or internal exposure to metals was observed. Nickel has been identified as the most common sensitizer, and also the most studied one. The coexistence of both allergic and autoimmune symptoms, induced by nickel, has been published, suggesting the autoimmune potential of nickel compounds. Conclusions: Clinical experience and scientific literature together demonstrate that metals may play an important role in the development of autoimmune diseases. While metal implant allergies and complications are on the rise, they remain a diagnostic and therapeutic challenge. Elucidation of their possible mechanisms will contribute to the more successful and safer treatment of affected individuals.

PLANEJAMENTO FAMILIAR COMO ASSUNTO DE MULHER!? PERFIL DE GÊNERO NA PRODUÇÃO CIENTÍFICA NO BRASIL

2019 ◽  
Vol 8 (1) ◽  
pp. 221-235 ◽  
Author(s):  
Daniella De Paula Chiesa ◽  
Mário Antônio Sanches ◽  
Daiane Priscila Simão-Silva
Keyword(s):  
Family Planning ◽  
Scientific Literature ◽  
State Of The Art ◽  
Health Sciences ◽  
Scientific Production ◽  
The State ◽  
Review Of The Literature ◽  
The Subject

O estudo do Planejamento familiar, no contexto da bioética, abre-se para diversas perspectivas, entre elas a valorização dos seus diferentes atores. Situado neste contexto o artigo tem como objetivo identificar o perfil de gênero na produção científica sobre Planejamento Familiar no Brasil, entre 2000 e 2014, assim como a área de formação e especialização dos autores. Foram utilizadas metodologias que permitiram mapear o estado da arte do tema estudado, a partir de uma revisão da literatura. O resultado da pesquisa identifica que a produção científica sobre Planejamento Familiar no Brasil se compõe de perfil destacadamente feminino (71,76%). Dos 73 artigos analisados, 42 (57,53%) o foco do tema está direcionado à mulher assim como evidencia-se a área de ciências da saúde com maior concentração das publicações do tema.  Este aspecto da pesquisa abre para uma realidade complexa onde se buscam criticamente as razões para a pesquisa em Planejamento Familiar ter ênfase na mulher e ser um tema de relevância nas ciências da saúde.Palavras-chave: Produção científica, Planejamento Familiar, Gênero.  ABSTRACT: The study of Family Planning, in the context of bioethics, opens to diverse perspectives, among them the appreciation of their different agents. Situated in this context the article aims to identify the profile of gender in scientific literature on Family Planning in Brazil, between 2000 and 2014, as well as the area of training and specialization of the authors. Methodologies were used which allowed to map the State of the art of the subject studied, from a review of the literature. The results found identify that the scientific production on Family Planning in Brazil is formed with a outstandingly female profile (71,76%). Of the 73 articles examined, 42 (57.53%) the focus of the topic is directed to women as well as showing the health sciences area with highest concentration of publications. This aspect of the research opens to a complex reality where we seek critically the reasons for Research in Family Planning have emphasis on woman and be a topic of relevance in health sciences.Keywords: Scientific Production, Family Planning, Gender.

scholarly journals Erythritol-Enriched Air-Polishing Powder for the Surgical Treatment of Peri-Implantitis

2015 ◽  
Vol 2015 ◽  
pp. 1-9 ◽  
Author(s):  
Silvio Taschieri ◽  
Roberto Weinstein ◽  
Massimo Del Fabbro ◽  
Stefano Corbella
Keyword(s):  
Surgical Treatment ◽  
Scientific Literature ◽  
Meta Analysis ◽  
Major Complication ◽  
Review Of The Literature ◽  
Implant Surface ◽  
Treatment Protocols ◽  
Air Polishing ◽  
Study Designs ◽  
Viable Treatment

Peri-implantitis represents a major complication that can compromise the success and survival of implant-supported rehabilitations. Both surgical and nonsurgical treatment protocols were proposed to improve clinical parameters and to treat implants affected by peri-implantitis. A systematic review of the literature was performed on electronic databases. The use of air-polishing powder in surgical treatment of peri-implantitis was investigated. A total of five articles, of different study designs, were included in the review. A meta-analysis could not be performed. The data from included studies reported a substantial benefit of the use of air-polishing powders for the decontamination of implant surface in surgical protocols. A case report of guided bone regeneration in sites with implants affected by peri-implantitis was presented. Surgical treatment of peri-implantitis, though demanding and not supported by a wide scientific literature, could be considered a viable treatment option if an adequate decontamination of infected surfaces could be obtained.

scholarly journals Constitutional features of the occurrence and course of psoriasis (analysis of scientific literature)

2019 ◽  
Vol 23 (3) ◽  
pp. 526-529
Author(s):  
Obadeh Bassam Abdel-Rahman Al-Qaraleh
Keyword(s):  
Web Of Science ◽  
Scientific Literature ◽  
Risk Groups ◽  
Psychological Problem ◽  
Review Of The Literature ◽  
Trigger Factors ◽  
Scientific Databases ◽  
Current State ◽  
The Right ◽  
Topical Area

The purpose of the work is to analyze the scientific literature on the constitutional features of the occurrence and course of psoriasis. The analysis of modern scientific literature in the scientific databases PubMed, eLIBRARY.RU and Web of Science was carried out. A review of the literature indicates the current state of the problem of such a disease as psoriasis, which is not only a skin lesion but also a serious socio-psychological problem. Given its chronic nature, lack of etiopathogenetic treatment, and knowing the trigger factors in the right way, it would be a good idea to look for early predisposition for the disease and to form risk groups for such individuals. Ideal in terms of efficiency and cheapness, given the results of the above studies, could be anthropological studies. The study of the constitutional features of the occurrence and course of psoriasis for the population of Ukraine is thus a priority and topical area of research.

scholarly journals Dental fear and anxiety in children: a review of the environmental factors

Folia Medica ◽  
2021 ◽  
Vol 63 (2) ◽  
pp. 177-182
Author(s):  
Maria P. Shindova ◽  
Ani B. Belcheva
Keyword(s):  
Pediatric Patients ◽  
Scientific Literature ◽  
Dental Fear ◽  
Review Of The Literature ◽  
Contributing Factors ◽  
Psychological Reactions ◽  
Behaviour Management ◽  
Factors Associated ◽  
Fear And Anxiety ◽  
Insight Into

Dental fear and anxiety are psychological reactions that interfere significantly with daily life. They are problems suffered by many patients worldwide that remain a significant challenge to providing adequate dental care. The multifactorial etiology of children’s dental fear and anxiety identifies the influence of many different risk factors in its development. The aim of this review article is to analyse the scientific literature regarding the different factors associated with dental fear and anxiety in children. Our review of the literature presents a critical analysis of the contributing factors in dental environment that have been investigated in the literature and provides an insight into the possible explanations on the influence of these factors in pediatric patients. Being familiar with these factors would facilitate behaviour management in anxious children. The findings of the literature review give grounds to undertake studies investigating the influence of contributing factors in all pediatric age subgroups.

Interpersonal Autonomic Physiology: A Systematic Review of the Literature

2016 ◽  
Vol 21 (2) ◽  
pp. 99-141 ◽  
Author(s):  
Richard V. Palumbo ◽  
Marisa E. Marraccini ◽  
Lisa L. Weyandt ◽  
Oliver Wilder-Smith ◽  
Heather A. McGee ◽  
...  
Keyword(s):  
Systematic Review ◽  
Scientific Literature ◽  
Physiological Activity ◽  
Social Processes ◽  
Review Of The Literature ◽  
Physiological Synchrony ◽  
Statistical Issues ◽  
Autonomic Physiology ◽  
Continuous Measures ◽  
The Relationship

Interpersonal autonomic physiology is defined as the relationship between people’s physiological dynamics, as indexed by continuous measures of the autonomic nervous system. Findings from this field of study indicate that physiological activity between two or more people can become associated or interdependent, often referred to as physiological synchrony. Physiological synchrony has been found in both new and established relationships across a range of contexts, and it correlates with a number of psychosocial constructs. Given these findings, interpersonal physiological interactions are theorized to be ubiquitous social processes that co-occur with observable behavior. However, this scientific literature is fragmented, making it difficult to evaluate consistency across reports. In an effort to facilitate more standardized scholarly approaches, this systematic review provides a description of existing work in the area and highlights theoretical, methodological, and statistical issues to be addressed in future interpersonal autonomic physiology research.

Lithium Plus Olanzapine: One of the Most Effective Combinations for Bipolar Disorder. A Case Report and a Concise Review of the Literature

2021 ◽  
Vol 18 ◽  
Author(s):  
Aitzol Miguélez Rodríguez ◽  
Xabier Pérez de Mendiola Etxezarraga
Keyword(s):  
Bipolar Disorder ◽  
Scientific Literature ◽  
Maintenance Phase ◽  
Mood Stabilizers ◽  
Review Of The Literature ◽  
Case Presentation ◽  
Concise Review ◽  
Second Generation Antipsychotics ◽  
Psychotic Features ◽  
Recurrent Nature

Background: The recurrent nature of Bipolar Disorder (BD) is the main cause of disability associated with the illness. Despite the proliferation of drugs approved for the maintenance phase of BD, the relapse rate is still high. The combination of drugs, especially the potentiation of mood-stabilizers with second-generation antipsychotics, may reduce the risk of relapse and rehospitalization. However, studies on the efficacy of specific combinations are scarce. Case presentation: The clinical case of a 28-year-old woman involuntarily admitted to an Acute Psychiatric Unit is presented. She suffers a manic postpartum episode with mixed and psychotic features. During the hospitalization, she is successfully treated with a combination of lithium plus olanzapine. In the discussion, a concise narrative review of the scientific literature on the efficacy of such a combination in BD is made. Conclusion: The association of lithium plus olanzapine is one of the combinations with most evidence on its efficacy in BD, especially in mixed-featured episodes. Tolerability concerns should not be an obstacle to its use, although they must be considered

Very young age of onset in trigemino-autonomic cephalalgias – case report and review of the literature

Cephalalgia ◽  
2020 ◽  
Vol 40 (12) ◽  
pp. 1385-1388
Author(s):  
Stefan Evers ◽  
Oliver Summ ◽  
Achim Frese
Keyword(s):  
Case Report ◽  
Young Children ◽  
Children And Adolescents ◽  
Scientific Literature ◽  
Age Of Onset ◽  
Paroxysmal Hemicrania ◽  
Review Of The Literature ◽  
Rare Disorders ◽  
Very Young Children ◽  
Chronic Course

Background Trigemino-autonomic cephalalgias are very rare disorders and even rarer in children and adolescents. We report the onset of paroxysmal hemicrania in a very young girl and reviewed the scientific literature for similar cases. Findings We describe the case of a 1.6-year-old girl with left-sided headache attacks fulfilling the criteria of paroxysmal hemicrania including prompt responsiveness to indomethacin. In addition, we detected at least two children for every trigemino-autonomic cephalalgias subtype with an age of under 7 years at the onset of the trigemino-autonomic cephalalgias. Remarkable features were a vast majority of chronic course from onset on and left-sided attacks. Conclusion Although very rare, trigemino-autonomic cephalalgias can occur even in very young children under the age of 6 years. This should be known in neuropaediatrics.

scholarly journals Immunological repertoire linked to PSTPIP1-associated myeloid-related inflammatory (PAMI) syndrome

2021 ◽  
Author(s):  
Leonardo Oliveira Mendonca ◽  
Maria Teresa Terreri ◽  
Fabiane Mitie Osaku ◽  
Samar Freschi Barros ◽  
Karen Francine Köhler ◽  
...  
Keyword(s):  
Clinical Data ◽  
Broad Spectrum ◽  
Genomic Dna ◽  
Index Patient ◽  
Clinical Impact ◽  
Autoinflammatory Disorders ◽  
Aberrant Expression ◽  
Standard Procedures ◽  
Papa Syndrome ◽  
Immunological Effects

Abstract Background: Mutations along PSTPIP1 gene are associated to two specific conditions, PAPA syndrome and PAMI syndrome, both autoinflammatory disorders associated to disturbances in cytoskeleton formation. Immunological aspects of PAMI syndrome has not yet been reported neither the clinical impact on therapeutical decisions.Methods: Clinical data of patients records were retrospectively accessed. Genomic DNA were extracted and sequenced following standard procedures. Peripheral lymphocytes were quantified in T, B e FOXP3 phenotypes.Results: We describe two related patients with PAMI syndrome harboring the usual E250K mutation. Anti-IL1 therapy could partially control the disease in the index patient. A broad spectrum of immunological effects as well as an aberrant expression of FOXP3 could be observed.Conclusions. Here we report two related brazilian patients with PAMI syndromes harboring the E250K mutation in PSTPIP1, their immunological aspects and the therapeutical response to canakinumab.

scholarly journals Effects of auriculotherapy in the treatment of nausea and vomiting: a systematic review

2022 ◽  
Vol 75 (1) ◽  
Author(s):  
Nathaly Bianka Moraes Fróes ◽  
Francisca Ariane de Souza Arrais ◽  
Priscila de Souza Aquino ◽  
Juliana Cunha Maia ◽  
Marianne Maia Dutra Balsells
Keyword(s):  
Systematic Review ◽  
Web Of Science ◽  
Scientific Literature ◽  
Intervention Group ◽  
Nausea And Vomiting ◽  
Review Of The Literature ◽  
Controlled Clinical Trials ◽  
Randomized Controlled Clinical Trials ◽  
Randomized Controlled ◽  
Different Populations

ABSTRACT Objectives: to identify the effectiveness of auriculotherapy in the treatment of nausea and vomiting through a systematic review of the scientific literature. Methods: it was performed a systematic review of the literature making use of the following data basis: The Scopus, PubMed, CINAHL (Cumulative Index to Nursing and Allied Health Literature), Web of Science, LILACS and Cochrane databases were used. Articles from complete research from randomized controlled clinical trials that describe using auriculotherapy in nausea and vomiting treatment were selected, without restriction of date or language. Results: eleven articles were selected for analysis. The majority approached the population in surgical situations, followed by patients undergoing chemotherapy and pregnant women. As for results, 81% (n=8) of the articles reported that nausea and vomiting were lower in incidence and/or intensity in the intervention group. Conclusions: the review provided relevant data on the effects of auriculotherapy in nausea and vomiting treatment, with a decrease in the intensity and frequency of these symptoms in different populations.

Animal-type melanoma: dog or wolf? A review of the literature and a case report

2018 ◽  
Vol 20 ◽  
Author(s):  
Luigia Stefania Stucci ◽  
Raffaele Palmirotta ◽  
Domenica Lovero ◽  
Erica Silvestris ◽  
Paola Cafforio ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Scientific Literature ◽  
Current Knowledge ◽  
Molecular Data ◽  
The Other ◽  
Review Of The Literature ◽  
Biological Behaviour ◽  
Melanocytic Lesions ◽  
Human Animal

AbstractThe human animal type melanoma (ATM) is a rare subtype of melanoma characterised by the proliferation of pigmented dermal epithelioid and spindled melanocytes. However, this variant of melanoma is still lacking a precise nosography definition and classification for the difficulty to be distinguished from other more common melanocytic lesions, as well as for its peculiar biological behaviour. On the other hand, the contribution of scientific literature to this issue is fragmented and limited to the description of very few cases. Starting from the presentation of a case with abnormally aggressive clinical features, here we revisit the current knowledge on ATM from its dermatologic patterns, epidemiology, demography and histopathology to the clinical management. Peculiar accuracy has also been reserved to several histopathologic criteria, which are critical for the differential diagnosis from other melanocytic diseases in junction with molecular data deriving from recent cytogenetic and mutational characterisation of this tumour.

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