scholarly journals Association Between KCNJ11 Gene E23K Polymorphism and Body Composition Together with Its Response to Endurance Training

2015 ◽  
Vol 9 (1) ◽  
pp. 121-125
Author(s):  
Zhou Duoqi ◽  
He Qing ◽  
Hu Yang ◽  
Li Yanchun ◽  
Xi Yi ◽  
...  

To explore the association between KCNJ11 gene E23K polymorphism of Chinese and body composition together with its response to endurance training. 102 biologically unrelated Han nationality male new recruits from northern China volunteered to execute a 5000-m running program, and the intensity is 95–105% individual lactate threshold. The protocol was lasted for 18 weeks, three times per week. The body composition index, including body weight (WT), lean body weight (LBW), body mass index (BMI) and body fat percentage (Fat%), was measured before and after training. PCR-RFLP was used to detect the KCNJ11 gene E23K polymorphism. Hardy-Weinberg equilibrium was observed for the frequency of genotypes in these subjects. Before training, WT, BMI and Fat% in KK group were significantly higher than those in EE and KK group (P<0.05 or P<0.01). There was no significant difference in LBW among groups (P>0.05). After training, the changes of all body composition index in KK group were bigger significantly greater than those in EE and EK groups (P<0.01). KCNJ11 gene E23K polymorphism might contribute to individual body composition together with its response to endurance training. The body fat content at baseline in KK was more than those in EE and EK groups, and it may hinder that individual to eliminate their body fat during endurance training.

2022 ◽  
Vol 8 (1) ◽  
pp. 1-6
Author(s):  
Reshma Shireesha ◽  
Obulesu Obulesu

Background: Aim: To assess the effect of exercise on body composition in obese and overweight. Methods: A total of seventy- two overweight subjects of either gender were enrolled for the study. Two groups were prepared. One group was experimental group (n=36) and the second group was control group (n=36). Parameter such as age, height and weight was recorded. On the basis of variables body mass Index and body fat percentage of every subject was determined. The experiment group were put on aerobic exercises spread over duration of four weeks. Results: The mean height in group I was 163.7 cm and 165.4 cm in group II. Weight was 65.2 kg and 63.5 kgs in group II, BMI (Kg/m2) was 29.4 and 29.1, body fat was 29.3% and 29.6% in group I and II respectively. A significant difference was observed (P< 0.05). The mean pre- test BMI was 29.6 and 38.5 and post- test value was 26.4 and 38.9 in group I and II respectively. A significant difference was observed (P< 0.05). Conclusions: Regular physical activity appears to confer a health benefit to the people. There was a positive relationship between aerobic exercises and overweight women in order to reduce the value of fat in the body.


Author(s):  
Reham A. Mostafa ◽  
Doaa R. Negm ◽  
Naser A. ElSawy

Background: Dual energy X-ray absorptiometry (DEXA) is the most accurate technique in determining fat percentage but it is unpotable, expensive, unavailable for general applicability. Objective: This study aimed to find the most accurate and easiest technique as alternative to DEXA for quick determination of body fat%. This study examined the accuracy of three models of Bioelectrical impedance analysis (BIA) technique (Fat Loss Monitor- Body Composition -Body Fat Analyzer) in determining the body fat percentage with using DEXA as a reference standard. Subject and Methods: A cross sectional study was carried out during the period from (28-9-2017) to (5-4-2018) among a random sample of (53) volunteers female student in Umm Al Qura University from Faculty of Applied Medical Science aged between (20-39 years) from different level of education. All subjects were generally healthy, data was collected through a structured questionnaire compose of three section. Demographic data was collected and anthropometric measurements were evaluated as well as body composition (Only body fat%) using DEXA, body composition monitor, fat loss monitor and body fat analyzer. Results: BMI classification of the total 53 subjects was including 8 healthy females, 17 overfat, 25 obese and 3 underweight. The fat% result from DEXA and body fat analyzer was significant difference at (P < 0.05). Fat percent result from DEXA and Body Composition device was non-significant difference at (P>0.05). The fat% result from DEXA and Fat Loss Monitor device was significant at difference (P<0.05). Conclusion: The most accurate of BIA technique was the Body Composition device compering to DEXA.


Fire ◽  
2018 ◽  
Vol 1 (3) ◽  
pp. 48 ◽  
Author(s):  
Callie Collins ◽  
Randall Brooks ◽  
Benjamin Sturz ◽  
Andrew Nelson ◽  
Robert Keefe

Wildland firefighting is arduous work with extreme physical and nutritional demands that often exceeds those of athletes competing in sports. The intensity and duration of job demands, impacts the amount of calories burned, which can influence body composition. The purpose of this study was to determine if the body composition of nine wildland firefighters working as smokejumpers changed throughout the 2017 fire season. Subjects (n = 9) for the study ranged in age from 24–49 (age 30.1 ± 8.3 y). Height (177 ± 18.8 cm) and weight (81.32 ± 6.39 kg) was recorded during initial body composition testing and body fat percentage was determined pre and post-season using Lange skinfold calipers. Outcomes were evaluated using a paired t-test. Body fat percentage was significantly different between pre and post-season (average body fat percentage increase = 1.31%; t = 2.31, p = 0.04, alpha = 0.05). Body weight increased slightly from pre to post-season (average increase in body weight: 0.17 kg), although the differences were not significant (t = 2.31, p = 0.78). Change in body fat percentage without change in body weight suggest that monitoring of WLFF body composition and fitness may be needed help inform dietary and fitness interventions to insure that nutritional demands of this population are sufficient to support physical work on the fireline.


Author(s):  
MYu Gavryushin ◽  
OV Sazonova ◽  
DO Gorbachev ◽  
LM Borodina ◽  
OV Frolova ◽  
...  

Traditionally, anthropometric method is used in clinical practice for the diagnosis of excess body weight. Obesity is the excess development of primarily visceral and subcutaneous adipose tissue, which can be diagnosed by bioimpedance analysis (BIA). The study was aimed to assess the role of BIA of body composition in the diagnosis of the physical development disorders in children and adolescents. Anthropometric assessment and BIA were performed in 431 Samara school students aged 12–16 of the health status groups I and II (230 boys and 201 girls). The results were analyzed with the use of the regional regression scores, BAZ indices, and the body fat percentage values. The results of estimation using the regression scores showed that 22.61% of boys and 23.43% of girls were overweight, while more than 2/3 of the sample had a normal pattern of physical development. The BAZ indices revealed a significantly higher proportion of overweight children among boys (25.7%), than among girls (11.5%, p < 0.01). The body fat percentage fluctuations based on the BIA data were found not only in children with disharmonious physical development, but also in 60% of children with normal body weight. Moreover, the data of BIA confirmed the body weight fluctuations, revealed with the use of the regression scores, in the significantly larger number of cases compared to the low body weight and excess body weight, diagnosed based on the BAZ indices. Accordingly, anthropometric analysis with the use of the regional regression scores may be used at the baseline for the early diagnosis of the nutritional status disorders in children. To confirm overweight and obesity in children, as well as to provide further treatment, the reliable method for estimation of the body fat content is required, which may be the method of BIA.


2021 ◽  
Author(s):  
Thiago Ramos de Barros ◽  
Verônica Pinto Salerno ◽  
Thalita Ponce ◽  
Míriam Raquel Meira Mainenti

ABSTRACT Introduction To train and prepare cadets for a career as firefighters in Rio de Janeiro, the second-year students of the Officers Training Course are submitted to a Search, Rescue, and Survival Training (SRST) course, which is characterized by long periods of high physical exertion and sleep restriction during a 9-day instruction module, and food restriction during a 7-day survival module. The present study investigated changes in the body composition of 39 male cadets submitted to SRST during training and 4 weeks of recovery with no restrictions in food consumption. Materials and Methods Each cadet was evaluated by anthropometric measurements at six time points: pre-SRST; after the first module; after the second module; and after 1, 2, and 4 weeks of recovery. Measurements included body girths and skinfolds, to estimate trunk (chest and waist) and limbs (arm and thigh) dimensions, as well as body composition. Repeated measures ANOVA and Friedman test were applied (depending on each data distribution). Results Statistically significant decreases in body weight (76.2; 69.8-87.2 to 63.9; 58.9-73.5 kg) and fat free mass (FFM, 69.2; 63.7-77.2 to 60.1; 56.2-68.0 kg) were observed following the second module of SRST. Following a single week of recovery, the FFM returned to pre-SRST values. Body weight returned to pre-training levels in 2 weeks. Body fat percentage and mass also significantly decreased during SRST (9.0; 7.7-12.3 to 6.5; 5.1-9.3% and 6.9; 5.6-10.0 to 6.9; 5.6-10.0 kg, respectively), which showed a slower and more gradual recovery that reached pre-SRST values after 4 weeks. The girths of arm, thigh, chest and waist significantly decreased due to SRST. The girths of the limbs (arm and thigh) returned to pre-training values after one month of recovery, while the girths of the trunk (chest and waist) did not return to pre-SRST values during the study period. Conclusions The findings suggest that men who experience periods of high energy demands and sleep restriction followed by a period of food restriction will endure unavoidable physical consequences that can be mostly reversed by a 1-month recovery.


Author(s):  
Wagner Luis Ripka ◽  
Eduardo Esmanhoto ◽  
Leandra Ulbricht

Percentile indicators, aided in its development by biomedical engineering, relative to body fat distribution in adolescents are able to help health professionals in better diagnosing overweight and obesity. The aim of this study was to calculate percentile values to body fat in adolescents aged between 12 and 17 years from the Curitiba-PR and its metropolitan region composed of 29 municipalities, having as reference method the dual energy x-ray absorptiometry (DXA) technology. After applying inclusion criteria for the adolescents, anthropometric measures of body fat and stature were taken, as well as evaluation of the body composition through DXA. The statistical analysis was grounded in the presentation of percentilic values developed by Cole and Green’s LMS method, where L stands for the skewness curve, M for the mean curve and S for the variance curve. In total, 390 boys were evaluated. The fat percentage values tend to show a decrease between the ages of 12 (22.8±5.1%) and 16 years (17.9±2.9%). Moreover, for the superior percentiles: 90th and 97th re-start to increase at the age of 17 after showing a decrease in the previous years. The L, M and S parameters, altogether with the percentiles created to evaluate body fat are interesting tools to tendency and evolution analyses, as well as to enable inferences to be made about the body composition of adolescents.


2020 ◽  
Vol 79 (OCE2) ◽  
Author(s):  
Monika Młodzik-Czyżewska ◽  
Anna Malinowska ◽  
Agata Chmurzynska

AbstractA link has recently been underlined between one-carbon metabolism and body weight and body composition, suggesting that folate may account for body mass determination and lipid metabolism. The aim of this study was thus to analyze whether folate intake is associated with body weight, body mass index (BMI), body fat percentage, and liver status.409 subjects aged 20–40 were enrolled in Poznań, Poland from 2016 to 2018. Food intake was assessed using three-day food records. Folate intake was calculated based on food composition tables using the Diet 5.0 program (National Food and Nutrition Institute, Poland). Weight to 0.1 kg and height to 0.01 m were measured using an electronic scale and a stadiometer, respectively. BMI was calculated as body weight in kilograms divided by height in meters squared. Fat mass and lean body mass were determined using whole-body air-displacement plethysmography (BodPod, Cosmed, Italy). Genotyping of rs1801133 (MTHFR) was performed with TaqMan probes. The following biomarkers of liver steatosis were calculated: NAFLD liver fat score (NAFLD-LFS), fatty liver index (FLI), and hepatic steatosis index (HSI). To analyze the associations between folate intake and the measured parameters, we used multiple regression with adjustments for age, sex, and energy intake.The mean body weight was 78.57 ± 18.14 kg, BMI 25.96 ± 5.28 kg/m2, and fat percentage 29.20% ± 10.78%. The median folate intake was 299.3 μg/day. Dietary folate intake was negatively associated with body weight, BMI, and body fat percentage (p < 0.05 for all associations). Folate intake was also associated with fatty liver indices—namely HSI (p < 0.05) and FLI (p < 0.05). There was no association between folate intake and NAFLD-LFS. MTHFR rs1801133 polymorphism was not associated with any of the measured parameters.Our findings suggest that folate intake may affect body weight and composition, as well as liver status. Higher folate intake could have a protective effect against obesity, but further studies are necessary to investigate the mechanism.The authors declare that they have no conflict of interests.This work was supported by the Polish National Science Centre(grants 2014/15/B/NZ9/02134 and 2016/21/N/NZ9/01195).


Author(s):  
Khaled Trabelsi ◽  
Kais el Abed ◽  
Stephen R. Stannard ◽  
Kamel Jammoussi ◽  
Khaled M. Zeghal ◽  
...  

The aim of this study was to evaluate the effects of aerobic training in a fasted versus a fed state during Ramadan on body composition and metabolic parameters in physically active men. Nineteen men were allocated to 2 groups: 10 practicing aerobic training in a fasted state (FAST) and 9 training in an acutely fed state (FED) during Ramadan. All subjects visited the laboratory for a total of 4 sessions on the following occasions: 3 days before Ramadan (Bef-R), the 15th day of Ramadan; the 29th day of Ramadan (End-R), and 21 days after Ramadan. During each session, subjects underwent anthropometric measurement, completed a dietary questionnaire, and provided fasting blood and urine samples. Body weight decreased in FAST and FED by 1.9% (p < .001) and 2.6% (p = .046), respectively. Body fat percentage decreased only in FAST by 6.2% (p = .016). FAST experienced an increase in the following parameters from Bef-R to End-R: urine specific gravity (0.64%, p = .012), urea (8.7%, p < .001), creatinine (7.5%, p < .001), uric acid (12.7%, p < .001), sodium (1.9%, p = .003), chloride (2.6%, p < .001), and high-density lipoprotein cholesterol (27.3%, p < .001). Of these parameters, only creatinine increased (5.8%, p = .004) in FED. Creatinine clearance values of FAST decreased by 8.9% (p < .001) and by 7.6% in FED (p = .01) from Bef-R to End-R. The authors conclude that aerobic training in a fasted state lowers body weight and body fat percentage. In contrast, fed aerobic training decreases only body weight. In addition, Ramadan fasting induced change in some metabolic parameters in FAST, but these changes were absent in FED.


1965 ◽  
Vol 43 (2) ◽  
pp. 297-308 ◽  
Author(s):  
J. S. Hayward

The body composition in terms of fat, water, and protein has been determined for 115 deer mice (genus Peromyscus) of six racial stocks. The changes in composition that are characteristic of seasonal extremes and that accompany laboratory acclimation are presented. The composition of the fat-free body exhibits the constancy which has been found in other mammals. Body protein averaged 22.97% and body water 69.71% of the fat-free body weight. Body fat levels are shown to vary considerably among individuals and races. The highest fat levels occurred in the desert-adapted race (P. m. sonoriensis). The importance of considering body composition in comparative studies of metabolic rate is discussed.


1997 ◽  
Vol 92 (5) ◽  
pp. 481-486 ◽  
Author(s):  
A. C. Hackney ◽  
W. Hezier ◽  
T. P. Gulledge ◽  
S. Jones ◽  
D. Strayhorn ◽  
...  

1. As an ancillary study carried out during the recently completed Multicenter Study of Hydroxyurea, we examined the effect of hydroxyurea on the body weight, body composition and exercise capacity of adult patients with sickle-cell anaemia. 2. The subjects received either hydroxyurea (six males and four females) or placebo (eight males and six females). Data for each subject were generated during four separate 24 h admissions to the General Clinical Research Center. These admissions occurred at baseline and then at 6, 12 and 18 months after the start of study drug (hydroxyurea or placebo) administration. During each admission, body composition was measured by using a dual X-ray absorptiometer, and exercise testing was performed by cycle ergometry. Anaerobic performance was assessed according to a ‘Wingate’ protocol (20 s at maximal intensity against a cycling resistance of 7.5% body weight). Aerobic performance was examined using a steady state submaximal exercise protocol (10 min cycling time). 3. At baseline, no significant difference in any parameter was found between the hydroxyurea- and placebo-treated groups. At 18 months, the hydroxy-urea-treated subjects exhibited an average weight gain of 3.16 kg. The mean weight gain in the placebo-treated subjects was 1.82 kg. Body composition analysis showed that the additional weight in both groups involved both lean and fat body mass components. In anaerobic performance, the subjects given hydroxyurea showed an increase in peak muscle power of 104.9 W. The placebo group also showed an increase, but theirs was a more modest gain of 57.7 W. The most marked improvement in anaerobic performance was observed in the hydroxyurea-treated men (P < 0.05). In aerobic performance, the hydroxyurea-treated subjects exhibited a decrease in peak heart rate response to a standardized workload of 15.2 beats/min, as compared with a decrease of only 4.3 beats/min in the placebo-treated patients. 4. Taken together, the overall weight gain, combined with increases in both anaerobic muscular performance and aerobic cardiovascular efficiency, provides objective data to support the subjective impression that hydroxyurea administration produces an improvement in the physical capacity of patients with sickle-cell anaemia.


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