scholarly journals Antibacterial and Antifungal Properties of persicaria odorata Leaf Against Pathogenic Bacteria and Fungi

2013 ◽  
Vol 4 (1) ◽  
pp. 71-74 ◽  
Author(s):  
P.M. Ridzuan
2020 ◽  
pp. 1-3
Author(s):  
Mithaiwala Idris A. ◽  
Suthar Hetal S. ◽  
Hetvi Soni ◽  
Ojha Sunil ◽  
Agrawal Amit

Present days due to the pathogenic bacteria and fungi, the human mortality rate has increased in number. The synthetic antimicrobial and antifungal are used in the treatment of various fungal and bacterial diseases, but have various side effects which limit's their use. Traditionally Pithecellobium dulce plant has been used for treatment of antifungal and antimicrobial infection. In this article we are comparing the activity of antimicrobial and antifungal properties of Pithecellobium dulce plant using leaves extract on gram negative bacteria,gram positive bacteria and fungi.Methanolic extraction of Pithecellobium dulce leaves was carried out using Soxhlet method and the phyto constitutional analysis was carried out for presenceof alkaloids, avonoids, glycosides, saponins, phytosterols, and triterpenoids.The inhibitory effect was determined by Cup plate method, by the measurement of zone of inhibition.The outcome was the leaves extract consisted of active phytoconstituents which were phenols, glycoside, sugar and avanoid due to which the extract showed signicant zone of inhibition,by which property of antibacterial and antifungal was listed. It can be concluded that the leaves of Pithecellobium dulce consist of active phytoconstituents which can be used as potent antimicrobials


2017 ◽  
Vol 35 (1) ◽  
pp. 10 ◽  
Author(s):  
R. R. Chand ◽  
A. D. Jokhan ◽  
R. D. Gopalan ◽  
T. Osborne

Natural products such as essential oils have been studied since ancient times to understand their biological properties. Essential oils are noted for their antimicrobial activity. Thus, the focus of this study was to evaluate the antimicrobial effect of five essential oils (EOs) from selected medicinal plants found in the South Pacific, on selected human pathogenic bacteria and fungi affecting agricultural industries. The disc diffusion method was carried out and the diameter of inhibition zones (mm) (DZI) using 0.25, 0.5, 5, 25, 50 and 100% (v/v) of essential oil concentrations were reported. The activity of Cananga odorata essential oils against Thermus thermophiles and Pseudomonas aeruginosa were among the selected bacteria that only showed the susceptibility at the lowest concentration (0.25% v/v). The diameter inhibition zones were 1.60 mm and 4.20 mm, respectively. The inhibitory effect of Ocimum tenuiflorum L essential oils at the highest concentration (100%) showed DZI ranging above 14 mm for all the selected bacteria and above 25 mm for the all selected fungi. The inhibitory effect of selected bacteria and fungi increased with stronger concentrations of essential oils. Hence, the essential oils from medicinal plants found in the South Pacific hold great potential for the antibacterial and antifungal properties.


2020 ◽  
Vol 75 (1-2) ◽  
pp. 1-5
Author(s):  
Ni Komang T. Dharmayani ◽  
Tsuyoshi Yoshimura ◽  
Elvira Hermawati ◽  
Lia D. Juliawaty ◽  
Yana M. Syah

AbstractA new phenolic sesquiterpene, dysoxyphenol (1), and the known sesquiterpene, 7R,10S-2-hydroxycalamenene (2), were isolated from the acetone extract of Dysoxylum densiflorum seeds. The structures of these compounds were determined based on physical, Nuclear Magnetic Resonance, and mass spectral data. Both compounds were evaluated for their antibacterial and antifungal properties against seven pathogenic bacteria and two wood-rotting fungi, respectively. The results showed that both compounds have significant antibacterial properties only against Bacillus subtilis (Minimum Inhibitory Concentration 28 μM), while in the antifungal evaluation compound 1 was found to be more active than compound 2. Therefore, compound 1 has promising antifungal properties that can be developed further for finding new antifungal agents.


2021 ◽  
Vol 31 (1) ◽  
Author(s):  
Rimashree Devi ◽  
Tankeswar Nath ◽  
Rashmi Rekha Boruah ◽  
Bishya Darphang ◽  
Pranab Kumar Nath ◽  
...  

Abstract Background Exploration of biocides in microbial system becomes increasingly interesting. Among the different microbial systems, the study of endophytes becomes an important field of research because of their agricultural as well as pharmaceutical importance. Bacterial endophytes from two medicinal plants from North Easter states of India had been studied for their potential antibacterial and antifungal properties. Results Bacterial endophytes from two medicinal plant species abundantly available in North Eastern states of India, Chirata (Swertia chirata) and Datura (Datura stramonium), had been isolated and studied for their anti-bacterial and anti-fungal activities. Six bacterial endophytes were isolated from Chirata and 5 from Datura. All these bacterial isolates were initially isolated by observing their colony morphology, and then 9 morphologically distinct bacterial isolates were identified at molecular level by their 16s rRNA sequencing. Among the identified isolates, 5 were found to be belonged to genus Staphylococcus, 2 Bacillus, and one each belonged to Rhodococcus and Cupriavidus. Antibacterial study was carried out against 2 plant pathogenic bacteria, viz., Xanthomonas oryzae and Ralstonia solanacearum. Antifungal study was carried out against 2 plant pathogenic fungi, viz., Fusarium oxysporum and F. solani. Out of 6 bacterial isolates from Chirata, one showed antibacterial as well as antifungal properties, and another one showed antifungal properties only. Likewise, out of 5 bacterial isolates from Datura, one found to have both antibacterial and antifungal properties, and another one has only antifungal properties. Conclusion Few bacterial endophytes isolated from S. chirata and D. stramonium L., abundantly available in North Eastern part of India, had potential antibacterial as well as antifungal properties. This could be considered as the baseline information on potential antibacterial and antifungal agents from bacterial endophytes. Further investigations are required to assess their efficacy against several other bacterial and fungal diseases of economic importance.


Nanomaterials ◽  
2018 ◽  
Vol 8 (8) ◽  
pp. 586 ◽  
Author(s):  
Mohammad Jalal ◽  
Mohammad Ansari ◽  
Mohammad Alzohairy ◽  
Syed Ali ◽  
Haris Khan ◽  
...  

The objective of the present study was one step extracellular biosynthesis of silver nanoparticles (AgNPs) using supernatant of Candida glabrata isolated from oropharyngeal mucosa of human immunodeficiency virus (HIV) patients and evaluation of their antibacterial and antifungal potential against human pathogenic bacteria and fungi. The mycosynthesized AgNPs were characterized by color visualization, ultraviolet-visible (UV) spectroscopy, fourier transform infrared spectroscopy (FTIR), and transmission electron microscopy (TEM). The FTIR spectra revealed the binding and stabilization of nanoparticles with protein. The TEM analysis showed that nanoparticles were well dispersed and predominantly spherical in shape within the size range of 2–15 nm. The antibacterial and antifungal potential of AgNPs were characterized by determining minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC)/ minimum fungicidal concentration (MFC), and well diffusion methods. The MBC and MFC were found in the range of 62.5–250 μg/mL and 125–500 μg/mL, which revealed that bacterial strains were more susceptible to AgNPs than fungal strains. These differences in bactericidal and fungicidal concentrations of the AgNPs were due to the differences in the cell structure and organization of bacteria and yeast cells. The interaction of AgNPs with C. albicans analyzed by TEM showed the penetration of nanoparticles inside the Candida cells, which led the formation of “pits” and “pores” that result from the rupturing of the cell wall and membrane. Further, TEM analysis showed that Candida cells treated with AgNPs were highly deformed and the cells had shrunken to a greater extent because of their interaction with the fungal cell wall and membrane, which disrupted the structure of the cell membrane and inhibited the normal budding process due to the destruction and loss of membrane integrity and formation of pores that may led to the cell death.


2008 ◽  
Vol 1 (1) ◽  
pp. 138-144 ◽  
Author(s):  
Tarannum Naz ◽  
Ashik Mosaddik ◽  
M. Ekramul Haque

  Antibacterial and antifungal properties of petroleum ether, chloroform, ethyl acetate and methanol extracts of Piper chaba (Choi) roots were studied by disc diffusion method and these activities were compared with primary standard drugs Kanamycin and Nystatin, respectively. The extracts were found to exhibit promising antibacterial and antifungal properties against Gram-positive, Gram-negative bacteria and fungi. The extracts were also studied for their cytotoxic activities by brine shrimp lethality bioassay, where gallic acid was used as primary standard. It was observed that the petroleum ether extract was potent cytotoxic with the LC50 value of 0.95 µg/ml against Artemia salina (L). The essential oils of the petroleum ether extract of Piper chaba roots were analysed by GC/MS. It was observed that most of the compounds were sesquiterpenes, some were long chain fatty acids and some were monoterpenes and alkaloids. Seventeen compounds were identified from the GC/MS analysis. Keywords: Piper chaba, antibacterial activity, antifungal activity, cytotoxicity. © 2009 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved. DOI: 10.3329/jsr.v1i1.1446


Author(s):  
Dilfuza Egamberdieva ◽  
Dilfuza Jabborova ◽  
Svetlana Babich ◽  
Sokhiba Xalmirzaeva ◽  
Kamaliddin Salakhiddinov ◽  
...  

AbstractIn traditional medicine of Uzbekistan, around 20% of herbal plants are used to treat various ailments, including diseases caused by pathogenic bacteria and fungi. Though conventional medicinal plants are common in Uzbekistan, many plant species potentially useful for new pharmaceuticals are less studied. They contain various biological compounds with antibacterial and antifungal activities, that could be developed into drugs. The search for novel antimicrobial compounds, especially against multidrug-resistant pathogens from aromatic and herbal plants is an essential scientific research line. However, the antimicrobial properties of several medicinally important plants from various countries are still unknown. This review aims to provide an up-to-date report on the antimicrobial activity of medicinal plants endemic to Uzbekistan widely used in traditional medicine.


2017 ◽  
Vol 82 (2) ◽  
pp. 117-125 ◽  
Author(s):  
Dongamanti Ashok ◽  
Reddy Vanaja ◽  
Mdderla Sarasija ◽  
Vijaya Lakshmi

Due to the potential antimicrobial activity of pyranochromenones and pyrazolines moieties, hybrid compounds containing both, substituted 4-Chloro-8-methyl-2-(1,3-diphenyl- -1H-pyrazol-4-yl)-1,5-dioxa-2H-phenanthren-6-ones (4a-g), have been synthesized from substituted (E)-1-(7-Hydroxy-4-methyl-8-coumarinyl)-3-(1,3-diphenyl -1H-pyrazol-4-yl)-2-propen-1-ones (3a-g) in good yield using the Vilsmeier reaction, by microwave-assisted method. The structures of all the compounds have been established on the basis of analytical and spectral data. All the synthesized compounds were tested in vitro for their antibacterial and antifungal activities. Some of the compounds have shown very good activity compared to standard drugs against all pathogenic bacteria and fungi.


Author(s):  
Bukola Christianah Adebayo-Tayo ◽  
Samuel Oluwadara Borode ◽  
Solomon Omoniyi Alao

Nanoparticles biosynthesis has been extensively studied for its biomedical applications. In this study, the in-vitro antibacterial and antifungal activity of greenly fabricated silver nanoparticles (NPs) from Senna alata leaf extract (SaAgNPs) and silver nanoparticle cream blend (SaAgNPs-cream blend) were investigated. The SaAgNPs were characterized using UV-visible spectrophotometry, FTIR, SEM, TGA, DLS, EDX, and XRD. The presence of surface plasmon band around 500 nm indicates AgNPs formation and functional groups such as alkenes, carboxylic acids, and alkyl aryl ether responsible for capping and stabilization of the nanoparticles. The SaAgNPs were spherical and 1.00 µm in size; TGA shows the formation of stable SaAgNPs, DLS shows 1.8 % intensity with 1905 nm average diameter and a polydispersity index of 0.595. EDX analysis confirmed the formation of pure silver nanoparticles. SaAgNPs supported the production of cosmetically acceptable SaAgNPs-cream blend with appropriate pH and viscosity. SaAgNPs and the SaAgNPs cream-blends had antibacterial activity against all and some of the test bacterial and fungal isolates. SaAgNPs had the highest activity against Pseudomonas aeruginosa 27853, Rhizopus sp. and Candida tropicalis with a zone of 16 mm and 30 mm. The cream-blends had activity against 68.75 % and 75 % of the test bacteria and fungi with the highest activity against Streptococcus epidermidis B (7.0 mm) and Candida albicans B (8.0 mm). In conclusion, the crude Senna alata leaf extracts, the bio-fabrication SaAgNPs and SaAgNPs-cream blend have antibacterial antifungal potentials which can be effectively utilized for the control of pathogenic bacteria and fungi.


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