A Review on Himalayan Medicinal Plants against Cancer

2021 ◽  
Vol 07 ◽  
Author(s):  
Bhuwan Chandra Joshi ◽  
Piyush Verma ◽  
Vijay Juyal ◽  
Archana N. Sah

Background: Plants contributed numerous novel compounds for prophylactic and curative medicine to modern science.They are the important source of natural agents used in various pharmaceutical industries. Himalayan plants are abundant in various secondary metabolites such as anthraquinones, flavonoids, tannins, alkaloids and terpenes. The Himalayan plants grown in high altitude and have around 6500 years old history as traditional medicines. Aim: This review article systematically presents information onHimalayan medicinal plants having anti-cancer potentials. Methodology: Around 160 articles were reviewed by using online search engines like PubMed, Scopus, Google Scholar, Web of Science, and floras of different Himalayan countries. Results: An attempt has been made to review anticancer plants and active constituents isolated from several anti-cancerous plants of Himalayan regions. Eighty three anticancer plants are reported in this review and total twenty two active chemical constituents including phenolic compounds, glycosides, terpenoidsand alkaloids from the plants were reported active against various cancer cell lines. Conclusion: Several synthetic agents are used to cure cancer but number of undesired side effects occurs during chemotherapy. Hence, the research is going on to investigate natural therapies, such as the use of the plant derived productsin cancer treatment. They may reduce adverse side effects.

Author(s):  
Vijay Kumar

: Mimosa pudica Linn is an integrated part of Traditional Medicines Systems of India, China, Africa, Korea and America. It has been used from centuries in traditional medicines to cure different diseases like fever, diabetes, constipation, jaundice, ulcers, biliousness, and dyspepsia. It is an important ingredient of wide class of herbal formulations. To assess the scientific evidence for therapeutic potential of Mimosa pudica Linn and to identify the gaps for future research. The available information on the ethno-medicinal uses, phytochemistry, pharmacology and toxicology of Mimosa pudica Linn was collected via a library and electronic searches in Sci-Finder, Pub-Med, Science Direct, Google Scholar for the period, 1990 to 2020. In traditional medicinal systems, variety of ethno-medicinal applications of Mimosa pudica Linn has been noticed. Phytochemical investigation has resulted in identification of 40 well known chemical constituents, among which alkaloids, phenols and flavionoids are the predominant groups. The crude extracts and isolates have exhibited a wide spectrum of in vitro and in vivo pharmacological activities including anti-cancer, anti-inflammation, osteoporosis, neurological disorders, hypertension etc.. To quantify the Mimosa pudica Linn and its formulations, analytical techniques like HPLC and HPTLC has shown dominancy with good range of recovery and detection limit. Mimosa pudica Linn is the well-known herb since an ancient time. The pharmacological results supported some of the applications of Mimosa pudica Linn in traditional medicine systems. Perhaps, the predominance of alkaloids, phenols and flavionoids are responsible for the pharmacological activities the crude extracts and isolates of Mimosa pudica Linn. Further, there is need to isolate and evaluate the active chemical constituents of Mimosa pudica Linn having significant medicinal values. In future, it is important to study the exact mechanism associated with the phytochemicals of Mimosa pudica Linn especially on anti-cancer activities. Notably, toxicity studies on Mimosa pudica Linn are limited which are to be explored in future for the safe application of Mimosa pudica Linn and its formulations.


Author(s):  
Noor Ali ◽  
Widad M K Al-Ani ◽  
Ibrahim S. Al-Jobouri

Evaluation of Iraqi medicinal plants is very crucial to help people avoid the use of herbs without prior knowledge which results in many side effects and sometimes even leads to death. The plant constituents vary according to season, weather and type of soil, therefore it is necessary to evaluate the chemical constituents and determine the time of collection of medicinal plants. In this research evaluation of the medicinal plant Calendula officinal grown in Iraq was performed by measuring the quantity of hyperoside found in the plant together with macroscopical and microscopical evaluation of the plant.


2003 ◽  
Vol 1 (2) ◽  
pp. 65-76 ◽  
Author(s):  
UDHI EKO HERNAWAN ◽  
AHMAD DWI SETYAWAN

Garlic has been used a long time ago as traditional medicines. The valuable bulb is used to treat hypertension, respiratory infection, headache, hemorrhoids, constipation, bruised injury or slice, insomnia, cholesterol, influenza, urinary infection, etc. Garlic bulbs can be used as anti-diabetic, anti-hypertension, anti-cholesterol, anti-atheroschlerosis, anti-oxidant, anti-cell platelet aggregation, fibrinolyse spur, anti-viral, anti-microbial, and anti-cancer. The ultimate bioactive compound of garlic is organo-sulphure components, i.e. alliin, allicin, ajoene, allyl sulphide groups, and allyl cystein. There was not any report of any side effects or toxicity of garlic.


BIBECHANA ◽  
2020 ◽  
Vol 17 ◽  
pp. 67-74
Author(s):  
Narendra Kumar Chaudhary ◽  
Rijan Ojha ◽  
Tilak Prasad Gautam

Ethnobotany gives the basic idea about the medicinal properties of plants. Identification of active compounds of the medicinal plants and their standardization is essential for the production of new drugs. In the present work, different parts of the five medicinal plants (Curcuma caesia, Costus speciosus, Drymaria cordata, Leea macrophylla, Plumbago zeylanica) were washed, air dried and crushed. Three different extracts of each powdered material were prepared and standard phytochemical analysis procedure was followed for the analysis of physicochemical properties of plants and the identification of active chemical constituents. Among 5 plants, the highest moisture content (14.83%) was found in Plumbago zeylanica, higher total ash (9.22%) and acid insoluble ash (4.43%) were observed in Cucurma caesia. Phytochemical analysis revealed the presence of 12 varieties of bioactive chemicals in the 5 different plants. The plants of the area have great diversity of phytochemicals of numerous medicinal properties. In conclusions, these five important medicinal plants could be useful for the people of the locality to cure several diseases as well as to generate the source of income. BIBECHANA 17 (2020) 67-74


2021 ◽  
Vol 1 (2) ◽  
Author(s):  
Ahmed Saeed Ali Kabbashi

Diabetes is a serious metabolic disorder and plenty of medical plants are used in traditional medicines to treat diabetes. These plants have no side effects, and many existing medicines are derived from the plants. The purpose of this systematic review is to study diabetes and to summarize the available treatments for this disease, focusing especially on herbal medicine


Author(s):  
Sherekar P. P.

The whole worldwide, now a days use many herbal product for healthy and happy life. In ancient system there are Ayurveda Siddha, Unani and Homoeopathy systems of medicines includes various different herbs, crude drugs, medicinal plants. Many ayurvedic herbs are known for its important medicinal property. Medicinal plants are mostly used for wide range of constituent present in it. In Ayurveda system of medicine, antimicrobial herbs find to be used in many ayurvedic preparations. Various antimicrobial herbs have been used against different microbial infection like bacteria, virus, fungi protozoa, helminths etc. and many more different infectious agent of different diseases. The active chemical constituents present in herbs or crude drug or medicinal plants inhibits the growth of microorganisms. The present attempt has been made to review studied various antimicrobial herbs.


2021 ◽  
Vol 07 ◽  
Author(s):  
Bhuwan Chandra Joshi ◽  
Vijay Juyal ◽  
Archana N. Sah ◽  
Piyush Verma ◽  
Minky Mukhija

Background: Cancer is a frightful disease and it is the second leading cause of death worldwide. Naturally derived compounds are gaining interest of research workers as they have less toxic side effects as compared to currently used treatments such as chemotherapy. Plants are the pool of chemical compounds which provides a promising future for research on cancer. Objective: This review paper provides updated information gathered on medicinal plants and isolated phytoconstituents used as anticancer agents and summarises the plant extracts and their isolated chemical constituents exhibiting anticancer potential on clinical trials. Methods: An extensive bibliographic investigation was carried out by analysing worldwide established scientific databases like SCOPUS, PUBMED, SCIELO, ScienceDirect, Springerlink, Web of Science, Wiley, SciFinder and Google Scholar etc. In next few decades, herbal medicine may become a new epoch of medical system. Results: Many researches are going on medicinal plants for the treatment of cancer but it is a time to increase further experimental studies on plant extracts and their chemical constituents to find out their mechanism of action at molecular level. Conclusion: The article may help many researchers to start off further experimentation that might lead to the drugs for the cancer treatment.


2017 ◽  
Vol 1 (2) ◽  
pp. 57-64
Author(s):  
Renny Agus Saktiawan ◽  
Atmiasri Atmiasri

ABSTRACT               Medicinal plants are a source of power that has existed since age-old. TOGA used by our ancestors in order to overcome health problems by making various ingredients of medicinal issues. Therefore the use of medicinal plant families or we called TOGA should be developed and circulated in the community, especially for all of households. But many people are still not aware of the utilization of family medicine. People often mistake them for the raw material too produce of traditional medicines and they do not understand yet how to process the material. It can cause side effects that are different for each person if given excessive doses of the drug. Health to our survival is very important, because without health we could not do any activities that can sustain our lifes. The method used observation and documentation. Medicinal plants are all kinds of plants that have their own uses as a medicine. Many parts of the plant can be used, such as the fruit, stems, leaves, and roots or tubers. Processing technology medicinal plants can be done by sorting, alteration, draining, and drying, storage, and so on. While herb processing can be done by grind, boil, and simmer.   Keywords: Medicinal plants, TOGA, Benefits, and Processing.


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