scholarly journals Influence of Hempedu bumi (Andrographis paniculata) on serum biochemical parameters and liver morphology in broiler chickens

2018 ◽  
Vol 3 (4) ◽  
Author(s):  
Masnindah Malahubban ◽  
Zakry Fitri Ab Ab Aziz

Serum biochemical parameters data was evaluated in broilers fed diets supplemented with  hempedu bumi (Andrographis paniculata, AP) ground leaf. Birds (n = 160) were assigned in four treatment groups with five replication and each group contain eight birds. Broilers in the control group were fed the basal diet without additives, the group dietary treatments, Diet AP2 (Basal diet + 2g/kg Andrographis paniculata); Diet AP4 (Basal diet + 4g/kg Andrographis paniculata) and Diet AP8 (Basal diet + 8g/kg Andrographis paniculata). During day-21 and day-42, five birds from each treatment groups were randomly selected for serum biochemical analysis which involve pancreatic, renal, and hepatic functions (aspartate transaminase (AST), alkaline transaminase (ALT), alkaline phosphatase (ALP), glucose, cholesterol, triglycerides, total protein, albumin, urea, sodium, potassium, chlorine, and globulins). Liver morphology was determined after slaughtering two birds and collected the liver samples. Based on these results AP at 8g/kg diet lowered serum cholesterol, glucose and triglycerides. It also maintain the normal structure of liver indicating that no toxic effect from AP supplementation at a rate up to 8 g/kg, it also that AP lowered ALP and ALT in blood of chicken. In conclusion, supplementation of AP at 8g/kg in diet its beneficial effects on health and safe for broiler chicken production.

2016 ◽  
Vol 7 ◽  
Author(s):  
Masnindah Malahubban ◽  
Zakry Fitri Ab Aziz

<p>To evaluate the effects of ground leaf of Misai kucing (<em>Orthosiphon stamineus</em>) as a dietary supplement on serum biochemical parameters and liver morphology. One hundred and sixty one-day old male broiler chickens (n=160) were distributed into four treatment groups, with five replicates of eight birds in each group: the control group (diet without additives); the group dietary treatments, Diet OS2 (Basal diet + 2g/kg <em>O. stamineus</em>); Diet OS4 (Basal diet + 4g/kg <em>O. stamineus</em>) and Diet OS8 (Basal diet + 8g/kg <em>O. stamineus</em>). After 42 days, 40 birds were randomly selected for serum biochemical profile analysis involving pancreatic, renal, and hepatic functions (urea, sodium, potassium, chlorine, aspartate transaminase (AST), alkaline transaminase (ALT), alkaline phosphatase (ALP), glucose, cholesterol, triglycerides, total protein, albumin, and globulins). Present study found that serum levels of cholesterol, triglycerides, urea, AST, ALT and ALP were significantly lower suggesting that the <em>O. stamineus</em> ground leaf possibly do not cause kidney and liver impairment, mainly, at the higher dosage (8g/kg). Present study concluded that the broiler chicken fed <em>O. stamineus</em> ground leaf at a rate 8 g/kg was the most promising dietary supplement to enhance health without deleterious effects on serum biochemical properties and morphological components of liver. In addition, it reduces abdominal fats and serum cholesterol. This study has provide evident that medicinal plant, <em>O. stamineus</em> can potentially substituted the use of additive synthetic.</p>


2015 ◽  
Vol 31 (4) ◽  
pp. 551-565 ◽  
Author(s):  
L. Allouche ◽  
T. Madani ◽  
Ait Hamouda ◽  
M.R. Boucherit ◽  
H. Taleb ◽  
...  

In developing countries, broiler farmers often use imbalanced energy diets, hence our study aims to evaluate the combined effect of addition of commercial exogenous enzymes (CEE), in low energy level corn/soybean meal based-diet on performance, serum biochemical parameters, meat characteristics in male and female of broiler chickens. A total of 120 one day old Hubbard F15 broiler chickens were divided on 2 groups (60 animals/group) with 5 replicates/group. The control group received a standard diet, while CEE group received the same diet supplemented with enzymes (250 g/ton). Addition of enzymes reduced significantly feed (p<0.001) and water intakes (p<0.05); in meantime, feed conversion ratio tended to be lower (p=0.08). No changes were observed in pH, protein or moisture contents of meat in both sexes broiler between CEE and control groups. No perturbation was found in all serum biochemical parameters in both sexes between CEE and control groups, except total protein and albumin levels were significantly higher in male birds fed enzymes when compared to male birds of the control group (p<0.001; p<0.01) respectively. Addition of enzymes allowed a decrease of 950 g/bird in feed intake for the total rearing period, hence save 337 ?/1000 birds; thus, use of CEE in hypocaloric diet enhances broilers feed efficiency and procures an economic benefit to farmers.


2019 ◽  
Vol 20 (4) ◽  
pp. 21-28
Author(s):  
Walaa Abu El-Ela ◽  
Kamel IAbou.Elazm ◽  
Sanaa Awad

Objective: To evaluate the anti-aflatoxin effects of Ginger and Nutritox® in white Pekin ducklings. Design: Randomized experimental study Animals: Ninty- one-day-old white Pekin ducklings. Procedure: Ducklings were alienated randomly into six equal groups, each group in 3 replicates (each replicate, n=5). Control group G1) was fed on commercial broiler basal diet without any medications, while other experimental groups, namely 2, 3, 4, 5 and 6 were received diet containing: G2) basal diet (BD) + 300 ppb AF (aflatoxin); G3) BD + 300 ppb AF + 250 mg kg-1 Gr (Ginger); G4) BD +300 ppb AF +1gm/kg feed Nutritox®; G5) BD + 250 mg kg-1 mg/kg of B.W Gr; G6) BD + 1gm/kg feed Nutritox® during study (1-14) days respectively. Results: Results showed that, addition of Ginger and Nutritox® ameliorated in different degrees the adverse effects of aflatoxin and improved growth performance and some serum biochemical parameters [Aspartate aminotransferase (AST), alanine aminotransferase (ALT) and Alkaline phosphatase (ALP)]. They hasten the recovery of antioxidant enzymes (MDA and GSH) in tissue to their normal levels during certain periods of our experiments. Histopathological liver changes run in the same track with biochemical results. Results revealed that administration of Ginger or Nutritox® in diet prevents and/or reduce some adverse effects of aflatoxin in ducks. Conclusion and clinical relevance: Our study indicates that ginger, an alternative natural product can provide protection against aflatoxin as Nutritox®.


2020 ◽  
Vol 15 (1) ◽  
pp. 1033-1041 ◽  
Author(s):  
Jun Yao ◽  
Lili Wang ◽  
Wenju Zhang ◽  
Mengjian Liu ◽  
Junli Niu

AbstractBackgroundThis study was conducted to investigate the effects of Bacillus megaterium on growth performance, serum biochemical parameters, antioxidant capacity, and immune function in suckling calves.MethodsIn total, 20 1-day-old Holstein calves with similar body weight (BW) and good health condition were randomly assigned into two groups with ten replicates per group and one calf per replicate. The control group (CON group) was fed a basal diet, whereas the B. megaterium group (BM group) was fed the basal diet supplemented with 500 mg/day/head of B. megaterium (1010 CFU/g) for 28 days.ResultsThe results revealed that the BM group showed an increase in final BW, daily weight gain, and feed-to-gain ratio (p < 0.05) and a decrease in diarrhea rate. Moreover, the concentrations of serum cholesterol and high-density lipoprotein decreased (p < 0.05) in the BM group compared with the CON group at 28 days. The level of serum glutathione was higher (p < 0.05) in the BM group than that of the CON group at 14 days, whereas the level of serum malondialdehyde decreased (p < 0.01) in the BM group compared with the CON group at 28 days. In addition, compared with the CON group (p < 0.05), the concentrations of serum IgA, IgM, IgG, and IL-4 were higher, whereas the concentration of serum TNF-α decreased in the BM group at 28 days.ConclusionB. megaterium had beneficial effects on the improvement of growth performance, immune function, and intestinal oxidative status of suckling calves.


2020 ◽  
Vol 45 (2) ◽  
pp. 96-105
Author(s):  
O. A. Adebiyi ◽  
T. A. Adefila ◽  
A.T. Adeshola

High cost of conventional feedstuffs has resulted to the need to exploit the diverse feed resources for improved sustainability in swine production. Hydroponic sprouts which undergo nutritional modification during the sprouting process are a good source of nutrients that could improve the performance of pigs. Hence, nutrient digestibility, performance, haematological and serum biochemical parameters of weaned pigs fed hydroponic maize fodder (HMF) and conventional basal based diets were studied. Thirty-six (36) crossbred weaned pigs were randomly allotted to three treatments with four replicates each in a completely randomized design. Treatment 1 (T1) had 50% hydroponically grown maize sprouts + 50% concentrate, Treatment 2 (T2) had 100% hydroponically grown maize sprouts and Treatment 3 (T3) had 100% basal diet (cassava peel +palm kernel cake +brewery dried grain). The experiment lasted 6 weeks. Significant differences (P<0.05) were observed in the apparent digestibility of nutrients, performance and blood profile of pigs across dietary treatments. T1 had higher (P<0.05) apparent crude protein digestibility (65.76%) while the lowest (55.27%) was observed in T2 with a similar trend observed for apparent crude fibre digestibility. Apparent ether extract digestibility was higher (P<0.05) in T2 (68.43%) and lowest in T3 (65.47%) while ash digestibility was (P<0.05) highest in T3 (46.08%). Significantly higher values were obtained in T3 for final weight (13.83kg), feed intake (12.79kg) and weight gain (3.83kg) while least values were observed in T2. However, T1 had the highest value for FCR (3.68kg) while comparable values were obtained for feed cost/weight gain in pigs fed T1 and T3. T1 had higher (p<0.05) RBC (5.73×10 µl), WBC (1.80×10 µl), lymphocytes (69%) and eosinophils (3.67%) values while lowest values were obtained in T2 for PCV (34.67%), RBC (5.08×10 µl) and lymphocytes (56.33%). Significant differences (P<0.05) were also observed for cholesterol, triglycerides, LDL, VLDL, total protein, globulin and albumin while glucose and HDL showed no differences (P>0.05). All values obtained for haematology and serum biochemical parameters were within the normal physiological range of the animals.In conclusion, hydroponics maize fodder when combined with concentrate feed had a positive impact on nutrient digestibility and performance of pigs. Also, haematological and serum biochemical indices of pigs were not negatively affected.


2020 ◽  
Vol 45 (3) ◽  
Author(s):  
U. Akpan ◽  
O. A. Bassey ◽  
C.O.N. Ikeobi ◽  
A.V. Jegede ◽  
O.A. Adebambo

This study investigated the genetic variation in carcass traits and blood parameters of local naked neck and normal-feathered chickens and their crosses with Marshall broiler chickens. Two hundred and sixty three chickens consisting of 50 purebred Marshalls (M), 38 naked neck (Nk) and 48 normal-feathered (N), 61Marshall x naked neck (MNk) and 66Marshall x normal-feathered(MN) chickens were used for the study. Data were collected on carcass traits, haematology and serum biochemical parameters and were analysed using the General Linear Model procedure of Statistical Analysis System. Carcass traits such as eviscerated weight and weights of thigh, drumstick, breast, wings and organs were significantly (P < 0.0001) affected by genotype. Results showed that the purebred Marshall had the highest values in most of the traits followed by their crossbreds. In organs such as gizzard, liver and heart the local normal feathered ranked equal with its crossbred. Sex significantly (P< 0.05) affected carcass traits. Males consistently had higher values than females in all the parameters measured. Genotype significantly (P


2014 ◽  
Vol 997 ◽  
pp. 178-184
Author(s):  
Hong Ling Wang ◽  
Yu Hong Yang ◽  
Jia Qing Wang ◽  
Zhuo Wang ◽  
Shuang Ma

This study aimed to investigate the efficacy of compound probiotics on broiler performance, intestinal microflora, immune function and serum biochemical indicators. Four hundred one-d-old female broiler chickens were randomly divided into 4 groups with 4 replicates in each group and 25 chickens per replication. The chickens in groupI(control group) were fed a basal diet, experimental groups II, III and IVwere fed the basal diet supplemented with 0.1%, 0.2% and 0.4% compound probiotics. The results of this work were as follows: (1) during the experimental period, compared with control group, the average daily in group III was significantly increased (P<0.05), the feed/gain and average daily feed intake were significantly lower (P<0.05); (2) at the age of 14 and 28 days, the number of cecal Lactic acid in group II and III were significantly higher than the control (P<0.05) and the content of E.coli has the opposite results. (3) the anti-body titer in group III was the highest, and significantly higher compared to the control (P<0.05), but there were no significantly differences between group IV and control group (P>0.05). (4) serum biochemical indexes of broilers in group III and IVwere significantly increased than that in control group (P<0.05). In conclusion, the supplementation of 0.2% compound probiotics could promote the growth performance, improve the cecal mico-ecosystem, enhance the anti-body titer and biochemical indexes in serum.


Author(s):  
S. Prakash ◽  
Jyoti Palod ◽  
R. K. Sharma ◽  
S. K. Singh

A trial was conducted for a period of 6 weeks to evaluate the effect of graded levels of nucleotide supplementation on serum biochemical parameters in Japanese quails. In the trial, 3 day old Japanese quail chicks were randomly distributed in completely randomized design into 4 treatment groups each with 3 replicates of 10 Japanese quails. The Japanese quails of treatment groups T1, T2, T3 and T4 were provided feed containing 0, 0.5, 1.0 and 1.5 per cent nucleotide respectively for a period of six weeks. At the end of experiment blood samples were collected for study of serum-biochemical parameters. The results indicated that decreased serum glucose, serum cholesterol and LDL cholesterol and increased HDL cholesterol was noticed in nucleotide supplemented groups at higher levels. Protein profile showed significant improvement in total protein, albumin and globulin while A/G ratio revealed no effect of supplementation. Serum creatinine and SGPT contents showed non-significance whereas, serum uric acid and SGOT contents were significantly (P<0.05) reduced in nucleotide supplemented groups of quails. It is concluded that nucleotide supplementation improves serum biochemical parameters without affecting liver and kidney functions.


Author(s):  
R. K. Yogi ◽  
A. Das ◽  
S. S. Kullu ◽  
M. Saini ◽  
A. K. Garg ◽  
...  

Twenty four male golden pheasants were divided into 4 groups of 6 each. First group basal diet contained no supplementary lutein or DL-methionine (M0C0). The diet of the birds in group M0C1 were supplemented with lutein (40 mg/kg DM) without supplementary DL methionine, whereas those in group M1C0 were supplemented only with DL-methionine (1.5g/ kg DM). Birds in group M1C1 were fed both the supplements. A feeding trial of 60 days duration was conducted. Heterophill counts was significantly lower (Pless than0.001) in groups M0C1 and M1C1 as compared to group M0C0 and M1C0 and lymphocyte count was higher (Pless than0.05) in lutein supplemented group as compared to non-lutein supplemented groups. The ratio of H: L was significantly higher (P less than 0.001) in lutein supplemented groups. Other haematological and serum biochemical parameters were not significantly different among the groups. Serum concentrations of corticosterone were lower (Pless than0.001) in groups M0C1 and M1C1 as compared to groups M0C0 and M1C0. It was concluded that supplementation of lutein (40mg/kg DM) but not DL- methionine (0.15% DM) improved the capability of the Golden pheasant to combat stress.


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