scholarly journals Efficacy of Ginger and Nutritox® in counteracting aflatoxin effects on white Pekin ducklings

2019 ◽  
Vol 20 (4) ◽  
pp. 21-28
Author(s):  
Walaa Abu El-Ela ◽  
Kamel IAbou.Elazm ◽  
Sanaa Awad

Objective: To evaluate the anti-aflatoxin effects of Ginger and Nutritox® in white Pekin ducklings. Design: Randomized experimental study Animals: Ninty- one-day-old white Pekin ducklings. Procedure: Ducklings were alienated randomly into six equal groups, each group in 3 replicates (each replicate, n=5). Control group G1) was fed on commercial broiler basal diet without any medications, while other experimental groups, namely 2, 3, 4, 5 and 6 were received diet containing: G2) basal diet (BD) + 300 ppb AF (aflatoxin); G3) BD + 300 ppb AF + 250 mg kg-1 Gr (Ginger); G4) BD +300 ppb AF +1gm/kg feed Nutritox®; G5) BD + 250 mg kg-1 mg/kg of B.W Gr; G6) BD + 1gm/kg feed Nutritox® during study (1-14) days respectively. Results: Results showed that, addition of Ginger and Nutritox® ameliorated in different degrees the adverse effects of aflatoxin and improved growth performance and some serum biochemical parameters [Aspartate aminotransferase (AST), alanine aminotransferase (ALT) and Alkaline phosphatase (ALP)]. They hasten the recovery of antioxidant enzymes (MDA and GSH) in tissue to their normal levels during certain periods of our experiments. Histopathological liver changes run in the same track with biochemical results. Results revealed that administration of Ginger or Nutritox® in diet prevents and/or reduce some adverse effects of aflatoxin in ducks. Conclusion and clinical relevance: Our study indicates that ginger, an alternative natural product can provide protection against aflatoxin as Nutritox®.

2018 ◽  
Vol 3 (4) ◽  
Author(s):  
Masnindah Malahubban ◽  
Zakry Fitri Ab Ab Aziz

Serum biochemical parameters data was evaluated in broilers fed diets supplemented with  hempedu bumi (Andrographis paniculata, AP) ground leaf. Birds (n = 160) were assigned in four treatment groups with five replication and each group contain eight birds. Broilers in the control group were fed the basal diet without additives, the group dietary treatments, Diet AP2 (Basal diet + 2g/kg Andrographis paniculata); Diet AP4 (Basal diet + 4g/kg Andrographis paniculata) and Diet AP8 (Basal diet + 8g/kg Andrographis paniculata). During day-21 and day-42, five birds from each treatment groups were randomly selected for serum biochemical analysis which involve pancreatic, renal, and hepatic functions (aspartate transaminase (AST), alkaline transaminase (ALT), alkaline phosphatase (ALP), glucose, cholesterol, triglycerides, total protein, albumin, urea, sodium, potassium, chlorine, and globulins). Liver morphology was determined after slaughtering two birds and collected the liver samples. Based on these results AP at 8g/kg diet lowered serum cholesterol, glucose and triglycerides. It also maintain the normal structure of liver indicating that no toxic effect from AP supplementation at a rate up to 8 g/kg, it also that AP lowered ALP and ALT in blood of chicken. In conclusion, supplementation of AP at 8g/kg in diet its beneficial effects on health and safe for broiler chicken production.


2020 ◽  
Vol 15 (1) ◽  
pp. 1033-1041 ◽  
Author(s):  
Jun Yao ◽  
Lili Wang ◽  
Wenju Zhang ◽  
Mengjian Liu ◽  
Junli Niu

AbstractBackgroundThis study was conducted to investigate the effects of Bacillus megaterium on growth performance, serum biochemical parameters, antioxidant capacity, and immune function in suckling calves.MethodsIn total, 20 1-day-old Holstein calves with similar body weight (BW) and good health condition were randomly assigned into two groups with ten replicates per group and one calf per replicate. The control group (CON group) was fed a basal diet, whereas the B. megaterium group (BM group) was fed the basal diet supplemented with 500 mg/day/head of B. megaterium (1010 CFU/g) for 28 days.ResultsThe results revealed that the BM group showed an increase in final BW, daily weight gain, and feed-to-gain ratio (p < 0.05) and a decrease in diarrhea rate. Moreover, the concentrations of serum cholesterol and high-density lipoprotein decreased (p < 0.05) in the BM group compared with the CON group at 28 days. The level of serum glutathione was higher (p < 0.05) in the BM group than that of the CON group at 14 days, whereas the level of serum malondialdehyde decreased (p < 0.01) in the BM group compared with the CON group at 28 days. In addition, compared with the CON group (p < 0.05), the concentrations of serum IgA, IgM, IgG, and IL-4 were higher, whereas the concentration of serum TNF-α decreased in the BM group at 28 days.ConclusionB. megaterium had beneficial effects on the improvement of growth performance, immune function, and intestinal oxidative status of suckling calves.


2020 ◽  
Vol 45 (2) ◽  
pp. 96-105
Author(s):  
O. A. Adebiyi ◽  
T. A. Adefila ◽  
A.T. Adeshola

High cost of conventional feedstuffs has resulted to the need to exploit the diverse feed resources for improved sustainability in swine production. Hydroponic sprouts which undergo nutritional modification during the sprouting process are a good source of nutrients that could improve the performance of pigs. Hence, nutrient digestibility, performance, haematological and serum biochemical parameters of weaned pigs fed hydroponic maize fodder (HMF) and conventional basal based diets were studied. Thirty-six (36) crossbred weaned pigs were randomly allotted to three treatments with four replicates each in a completely randomized design. Treatment 1 (T1) had 50% hydroponically grown maize sprouts + 50% concentrate, Treatment 2 (T2) had 100% hydroponically grown maize sprouts and Treatment 3 (T3) had 100% basal diet (cassava peel +palm kernel cake +brewery dried grain). The experiment lasted 6 weeks. Significant differences (P<0.05) were observed in the apparent digestibility of nutrients, performance and blood profile of pigs across dietary treatments. T1 had higher (P<0.05) apparent crude protein digestibility (65.76%) while the lowest (55.27%) was observed in T2 with a similar trend observed for apparent crude fibre digestibility. Apparent ether extract digestibility was higher (P<0.05) in T2 (68.43%) and lowest in T3 (65.47%) while ash digestibility was (P<0.05) highest in T3 (46.08%). Significantly higher values were obtained in T3 for final weight (13.83kg), feed intake (12.79kg) and weight gain (3.83kg) while least values were observed in T2. However, T1 had the highest value for FCR (3.68kg) while comparable values were obtained for feed cost/weight gain in pigs fed T1 and T3. T1 had higher (p<0.05) RBC (5.73×10 µl), WBC (1.80×10 µl), lymphocytes (69%) and eosinophils (3.67%) values while lowest values were obtained in T2 for PCV (34.67%), RBC (5.08×10 µl) and lymphocytes (56.33%). Significant differences (P<0.05) were also observed for cholesterol, triglycerides, LDL, VLDL, total protein, globulin and albumin while glucose and HDL showed no differences (P>0.05). All values obtained for haematology and serum biochemical parameters were within the normal physiological range of the animals.In conclusion, hydroponics maize fodder when combined with concentrate feed had a positive impact on nutrient digestibility and performance of pigs. Also, haematological and serum biochemical indices of pigs were not negatively affected.


Author(s):  
R. K. Yogi ◽  
A. Das ◽  
S. S. Kullu ◽  
M. Saini ◽  
A. K. Garg ◽  
...  

Twenty four male golden pheasants were divided into 4 groups of 6 each. First group basal diet contained no supplementary lutein or DL-methionine (M0C0). The diet of the birds in group M0C1 were supplemented with lutein (40 mg/kg DM) without supplementary DL methionine, whereas those in group M1C0 were supplemented only with DL-methionine (1.5g/ kg DM). Birds in group M1C1 were fed both the supplements. A feeding trial of 60 days duration was conducted. Heterophill counts was significantly lower (Pless than0.001) in groups M0C1 and M1C1 as compared to group M0C0 and M1C0 and lymphocyte count was higher (Pless than0.05) in lutein supplemented group as compared to non-lutein supplemented groups. The ratio of H: L was significantly higher (P less than 0.001) in lutein supplemented groups. Other haematological and serum biochemical parameters were not significantly different among the groups. Serum concentrations of corticosterone were lower (Pless than0.001) in groups M0C1 and M1C1 as compared to groups M0C0 and M1C0. It was concluded that supplementation of lutein (40mg/kg DM) but not DL- methionine (0.15% DM) improved the capability of the Golden pheasant to combat stress.


PLoS ONE ◽  
2021 ◽  
Vol 16 (9) ◽  
pp. e0256661
Author(s):  
Fatima Dikhanbayeva ◽  
Elmira Zhaxybayeva ◽  
Zhuldyz Smailova ◽  
Arman Issimov ◽  
Zhechko Dimitrov ◽  
...  

This study aimed to assess potential feeding effect of camel milk curd mass and its mixes to experimental rat’s blood serum biochemical parameters, enzymatic activity and the peptide toxicity. Fifty healthy male Sprague-Dawley rats were divided into five groups (n = 10 each). Each group was fed with camel milk pure curd mass and its mixes for 16 days. At the end of the experiment, rats were sacrificed to collect the samples from the blood serum. Blood serum biochemical parameters total protein, cholesterol, glucose, albumin, triglycerides; the enzymatic activities of alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase were determined on the A25 automatic analyser, and peptide toxicity analysed by the reference method. The statistical data have shown no significant differences in body weight gain in all groups. Total protein decreased in group II, IV, and V; however, it increased in group III compared to the control group. Cholesterol grew up in group II and it slightly increased in group V, dropped in groups III and IV compared to group I result. Glucose increased in groups II, III, IV compared to group I; still, group V results show a slight decrease. Albumin decreased in group IV, yet in group V it increased than the group I result. Simultaneously, groups II and III results were changed with less percentage. Triglyceride grew up in groups II, V, and it dropped significantly in groups III, IV compared to the control group. De Ritis ratio of enzymes in groups II, III, and IV fluctuated between 1.31 and 0.98 IU/L; however, group V demonstrated significant data versus group I. Diets peptide toxicity in all groups was lower than control group data. The experimental results indicated that curd mass from camel milk could be used as a pure or with additives and it did not discover the observed side effects.


Author(s):  
Peter-Damian Chukwunomso Jiwuba ◽  
Ekeno Michael Assam ◽  
Eka Christian Inyang

The effects of fufu sieviate meal based diets at 0%, 20%, 40% and 60% levels using Panicum maximum as the basal on the haematological and serum biochemical parameters of West African dwarf (WAD) goats were studied for 87 days. Thirty six blood samples were collected from the WAD goats and their haematological and serum biochemical indices were determined using Beckman Coulter Ac-T10 Laboratory Haematology Blood Analyzer and Bayer DCA 2000+ HbA1c analyzer, respectively using a completely randomized design. Packed cell volume (PCV) was better (p<0.05) at T1 than the other treatments. Red Blood Cell (RBC) and mean corpuscular haemoglobin (MCH) were numerically improved at T2, T3 and T4 than in the control group while lymphocyte increased significantly (P<0.05) with increasing levels of the test ingredient. Results on serum biochemical indices showed that serum urea, creatinine, glucose and ALP differed significantly (P<0.05) and tended to be higher in the treatment (T2, T3 and T4)groups than the control group. The study therefore revealed that inclusion of fufu sieviate in the diets of West African Dwarf goats had no deleterious effects on the haematological and serum biochemical parameters of WAD goats and could be included up to 60% in goat diets.


Author(s):  
Goze N. Bernard ◽  
N’Dri N. Mathieu ◽  
Yapo A. Paul

Background: In the framework of the valorization of traditional medicine, the biotolerance study of a hydroethanol 70% extract from trunk bark of Terminalia superba (HE 70%) Engl. and Diels (Combretaceae), a medicinal plant used for the treatment of gastric ulcer in Côte d'Ivoire was carried out by oral administration repeated for 28 days to three rat groups at doses 250, 500 and 750 mg/kg per body weight (b.w.).Methods: Fifty rats were randomly divided in four groups of ten animals including three test groups and one control group. Each group included five male and five female rats. An additional satellite group of ten rats in group treated at high dose (750mg/kg b.w.) was included in order to observe reversibility, persistence or late appearance of toxic effects at least 14 days after stopping the treatment. Three doses were prepared (250; 500 and 750mg/kg b.w.) corresponding to extract concentrations (12.5; 25 and 37.5mg/ml) were given to groups B, C and D respectively. Group A, served as control group, received distilled water at 2ml/kg b.w. Groups B, C and D, received orally HE 70% extract at 250, 500 and 750mg/kg respectively. Serum AST, ALT, total and direct bilirubin, total, HDL, LDL-cholesterols, triglycerides, urea and creatinine were estimated using standard methods.Results: The blood withdrawal analysis done previously (day 0) and at the end of every week on dry tubes revealed that at all weeks and for all doses, this extract do not affect serum values of total and direct bilirubin, creatinine, total, HDL, LDL-cholesterols and triglycerides. Oppositely, this extract reduced significantly (P<0.05) ALT serum rate at the 14th and 28th day at 750mg/kg b.w. respectively. In addition, at the 28th day, AST rate decreased significantly (P<0.05) at 750mg/kg b.w. Glycemia showed a significant (P <0.05) reduction at the 28th day at doses 500 and 750 mg/kg b.w. In contrast, urea increased significantly (P<0.05) at the 28th day at 500mg/kg b.w.Conclusions: This study showed that the use of a hydroethanol 70% extract from trunk bark of T. superba would be hepatoprotective, nontoxic for kidneys, liver and hypoglycemic at the studied doses.


Author(s):  
A. K. Chaturvedani ◽  
Sudhir Kumar Jaiswal ◽  
Meesam Raza

The present study was conducted to assess the effects of thermal stress on the serum biochemical and haematological parameters in broiler chicken. Forty CARIBRO- Vishal broiler chicken were divided into two groups with twenty birds each. The control group was kept at room temperature and treatment group was exposed to thermal stress under 40±1 °C for 4 hours at 35 day of age. The exposure of thermal stress significantly increased (P less than 0.05) the value of serum biochemical parameters (glucose, cholesterol and triglyceride), heterophills, H/L ratios and basophills, however the value of total leukocyte, haemoglobin, haematocrit value, and monocytes decreased significantly (P less than 0.05).


Author(s):  
T.C. Nayak ◽  
A.P. Singh ◽  
A. Chahar ◽  
Savita . ◽  
R. Yadav ◽  
...  

Background: The objective of the present study was to evaluate the changes in serum biochemical parameters in colibacillosis affected diarrhoeic cattle calves below one month of age. Methods: The study was undertaken at Veterinary Clinical Complex, College of Veterinary and Animal Science, Rajasthan University of Veterinary and Animal Sciences, Bikaner, Rajasthan, India, during the period from September 2018 to March 2019. A total of 32 calves affected with colibacillosis confirmed on the basis of Multiplex PCR (for presence of K99, Stx1 and eaeA genes of E. coli) and eight clinically normal healthy calves (as control) were taken to investigate the serum biochemical profiles. Result: Analysis of serum samples of calves affected with colibacillosis revealed significant increase in the values of total protein, albumin, globulin, A/G ratio, blood urea nitogen, creatinine, potassium, total oxidant status andoxidative stress index while there is a significant decrease in the values of glucose, sodium, chloride, bicarbonate, IgG, IgM and total antioxidant status. There were no significant changes observed in the values of ALP, AST and ALT in affected calves as compared to healthy control group of calves.


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