scholarly journals Awareness, knowledge, perceived benefits, and barriers regarding precision medicine and willingness to participate in a national registry: Comparison of cancer patients and the general population (Preprint)

2019 ◽  
Author(s):  
Mangyeong Lee ◽  
Juhee Cho ◽  
Sun-Young Kong ◽  
JunghHee Yoon ◽  
Danbee Kang ◽  
...  
Keyword(s):  
Personalized Medicine ◽  
General Population ◽  
Precision Medicine ◽  
Cancer Patients ◽  
National Registry ◽  
Willingness To Participate ◽  
Perceived Benefits ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Area Of Interest

BACKGROUND Precision medicine (PM) is a growing area of interest in cancer care. Although the terms ‘precision medicine’ and ‘personalized medicine’ are used interchangeably, the former may be new both to cancer patients and the general population. Most previous studies evaluated peoples’ attitudes towards genetic testing as a part of personalized medicine and included a single stakeholder, either patients or the general population. Few studies have evaluated cancer patients’ knowledge and perception regarding PM. OBJECTIVE To evaluate cancer patients’ awareness, knowledge, as well as perceived benefits and barriers regarding PM, and their willingness to participate in a national registry for PM, in comparison to those of the general population. METHODS We conducted a cross-sectional survey on 1,500 consecutive cancer patients enrolled at two university-based cancer hospitals in Seoul, Korea; 1,500 people who were representative of the Korean population were enrolled as controls. Multivariable logistic regression was conducted to identify the factors associated with a willingness to participate in a national registry for PM. RESULTS : In the total population, 20.0% of the cancer patients had heard of PM and 35.1% were able to accurately define it. Cancer patients were three times likelier to express a willingness to participate in a national registry for PM than the general population (95% confidence interval [CI], 2.47-3.61). Participants who had heard of PM (cancer patients: adjusted odds ratio (aOR) = 1.40, 95% CI, 1.00-1.95; general population: aOR = 2.04, 95% CI, 1.62-2.56) and who had a more positive perception of the PM-related benefits (cancer patients: aOR = 2.48, 95% CI, 1.88-3.27; general population: aOR = 1.34, 95% CI, 1.05-1.71) were likelier to be willing to participate in a national registry for PM. CONCLUSIONS While PM is gaining importance in clinical settings, a majority of cancer patients are not well-informed about it. Nevertheless, the patients in our study perceived PM as being associated with various benefits and showed a willingness to participate in a national registry for PM. Considerable efforts need to be taken to educate the public and advocate participation in studies on PM

scholarly journals Awareness, Knowledge, Perceived Benefits, and Barriers Regarding Precision Medicine and Willingness to Participate in a National Registry: Comparison of Cancer Patients and the General Population

2021 ◽  
Author(s):  
Mangyeong Lee ◽  
Juhee Cho ◽  
Sun-Young Kong ◽  
Junghee Yoon ◽  
Danbee Kang ◽  
...  
Keyword(s):  
General Population ◽  
Precision Medicine ◽  
Cancer Patients ◽  
National Registry ◽  
Willingness To Participate ◽  
Perceived Benefits ◽  
Cross Sectional Survey ◽  
Factors Associated ◽  
Area Of Interest ◽  
Correct Definition

Abstract Background Precision medicine (PM) is a growing area of interest in cancer care. However, relatively little is known about the public attitudes toward PM and the factors associated with the willingness to participate in the construction of national registries for PM. Methods A cross-sectional survey was conducted with 1,500 cancer patients and 1,496 general population in South Korea from November 2016 to February 2017. We evaluated cancer patients’ awareness, knowledge, as well as perceived benefits and barriers regarding precision medicine (PM), and their willingness to participate in a national registry for PM, compared to the general population. Logistic regression analysis was performed to identify the factors associated with the willingness to participate in a national registry for PM. Results 1,500 cancer patients and 1,496 general population were recruited for the study. Cancer patients were less likely to have heard of PM than the general population (20.0% and 33.1%, P < .001), 34.2% of the participants knew the correct definition of PM. Cancer patients were more likely to However, fewer study participants in both groups said they would like to share their personal health data for PM, compared to the number of people who are willing to participate. Cancer patients (aOR 2.98, 95% CI, 2.47–3.61), participants who had heard of PM before (aOR 1.40, 95% CI, 1.00-1.95), had greater perceived benefits (aOR, 2.48, 95% CI, 1.88–3.27) and fewer perceived barriers (aOR 1.57, 95% CI, 1.18–2.08) regarding PM were more likely to have the willingness to participate in the registry compared to those who did not. Conclusions Cancer patients were more likely to have greater perceived benefits of PM and higher willingness to participate in the related study than the general population. However, both two groups were still informed about PM well. This study suggests considering the provision of information and education about PM such as expected values and required roles both to the general population and cancer patients.

scholarly journals Knowledge, Attitude and Practices on Cancer Education and Prevention: A Cross-Sectional Survey

2018 ◽  
Vol 4 (Supplement 2) ◽  
pp. 196s-196s
Author(s):  
S. Ghose ◽  
S.S. Datta
Keyword(s):  
General Population ◽  
Cancer Patients ◽  
Cancer Education ◽  
Cancer Knowledge ◽  
Cancer Awareness ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Screening Programs ◽  
Significant Difference ◽  
Community Dwellers

Background: Lifestyle associated cancers are 1 of the top 5 leading causes of death in the world and India sees a million new cases yearly. Early detection is an effective way to reduce incidences and mortality for preventable cancers. There is significant delay in detection for a large proportion of cancer patients in India. Lack of awareness about cancer has been shown to be a major contributor to treatment delay in many countries. The current study looked at the cancer awareness in an urban Indian population to address the gap of information about cancer prevention. Aim: To quantify knowledge about cancer in an urban population and find sociodemographic associations of lack of knowledge. We also wanted to compare knowledge of people from general population with those having some knowledge due to a family member being under treatment. Methods: Data were collected from 2 stratums: family members of cancer patients, Internet using community from general population, non-Internet using community dwellers. Subject selection was randomized. A prevalidated questionnaire was used. Data were analyzed using STATA 13. Results: Respondents (n = 846) were family of cancer patients (n = 146, 17.3%), community dwellers (n = 175, 20.7%) and community Internet users (n = 525, 62.1%). No association of knowledge with age, gender, and income was found ( P values 0.84, 0.25, 0.93 respectively). Statistically significant association of cancer knowledge with education was found ( P < 0.001). There is significant difference in knowledge between Internet using and non-Internet using community ( P < 0.001). Conclusion: Education impacts cancer knowledge of the population. The population having access to Internet has a higher knowledge than nonusers; but exposure to cancer treatment does not result in higher knowledge on cancer. These results will inform prevention and health education policies and aid in designing awareness and screening programs for preventing cancer.

AWARENESS ABOUT INDOOR AIR POLLUTION IN GENERAL POPULATION OF RAWALPINDI AND ISLAMABAD

2018 ◽  
Vol 8 (2) ◽  
pp. 80-83
Author(s):  
Nadia Tariq ◽  
Tamkeen Jaffry ◽  
Rahma Fiaz ◽  
Abdul Majid Rajput ◽  
Sadaf Khalid
Keyword(s):  
Air Pollution ◽  
General Population ◽  
Indoor Air ◽  
Indoor Air Pollution ◽  
Economic Status ◽  
Educational Status ◽  
Epidemiological Studies ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Significant Difference

Background: Indoor air pollutants are increasingly being associated with respiratory illnesses leading to high degree of morbidity and mortality. There are not sufficient epidemiological studies from Pakistan which assess level of awareness of indoor air pollution resulting in respiratory diseases in population. Methods: This cross sectional survey was carried out on general population of Rawalpindi/Islamabad. Sample size was 223 study subjects selected by non-probability convenient sampling. Knowledge of the study subjects was determined with regard to indoor air pollution, its effects on health and different sources of indoor air pollution with the help of a questionnaire. The influence of age, gender, educational status and socio economic status on the level of awareness was also analyzed. Results: Out of total 223 participants, 115 were males and108 females. Participants aware of indoor air pollution were 91.5% and adequate awareness about its sources was 80.7%. Those who knew indoor air pollution is detrimental to health were 95.1%. Awareness about building construction dust as source of indoor air pollution was maximum (84.8%). There was significant difference in awareness among participants with different monthly incomes and educational status and also between males and females. Conclusion: This study concludes that general population of Rawalpindi/Islamabad has fairly good awareness about sources of indoor air pollution. Use of harmful material causing indoor air pollution should be limited or substituted with better ones where possible.

Psychological Impacts of COVID-19 During the First Nationwide Lockdown in Vietnam: Web-Based, Cross-Sectional Survey Study (Preprint)

2020 ◽  
Author(s):  
Khanh Ngoc Cong Duong ◽  
Tien Nguyen Le Bao ◽  
Phuong Thi Lan Nguyen ◽  
Thanh Vo Van ◽  
Toi Phung Lam ◽  
...  
Keyword(s):  
Psychological Distress ◽  
General Population ◽  
Psychological Health ◽  
Online Survey ◽  
Survey Study ◽  
Limited Information ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Event Scale ◽  
The Impact

BACKGROUND The first nationwide lockdown due to the COVID-19 pandemic was implemented in Vietnam from April 1 to 15, 2020. Nevertheless, there has been limited information on the impact of COVID-19 on the psychological health of the public. OBJECTIVE This study aimed to estimate the prevalence of psychological issues and identify the factors associated with the psychological impact of COVID-19 during the first nationwide lockdown among the general population in Vietnam. METHODS We employed a cross-sectional study design with convenience sampling. A self-administered, online survey was used to collect data and assess psychological distress, depression, anxiety, and stress of participants from April 10 to 15, 2020. The Impact of Event Scale-Revised (IES-R) and the Depression, Anxiety, and Stress Scale-21 (DASS-21) were utilized to assess psychological distress, depression, anxiety, and stress of participants during social distancing due to COVID-19. Associations across factors were explored using regression analysis. RESULTS A total of 1385 respondents completed the survey. Of this, 35.9% (n=497) experienced psychological distress, as well as depression (n=325, 23.5%), anxiety (n=195, 14.1%), and stress (n=309, 22.3%). Respondents who evaluated their physical health as average had a higher IES-R score (beta coefficient [B]=9.16, 95% CI 6.43 to 11.89), as well as higher depression (B=5.85, 95% CI 4.49 to 7.21), anxiety (B=3.64, 95% CI 2.64 to 4.63), and stress (B=5.19, 95% CI 3.83 to 6.56) scores for DASS-21 than those who rated their health as good or very good. Those who self-reported their health as bad or very bad experienced more severe depression (B=9.57, 95% CI 4.54 to 14.59), anxiety (B=7.24, 95% CI 3.55 to 10.9), and stress (B=10.60, 95% CI 5.56 to 15.65). Unemployment was more likely to be associated with depression (B=3.34, 95% CI 1.68 to 5.01) and stress (B=2.34, 95% CI 0.84 to 3.85). Regarding worries about COVID-19, more than half (n=755, 54.5%) expressed concern for their children aged &lt;18 years, which increased their IES-R score (B=7.81, 95% CI 4.98 to 10.64) and DASS-21 stress score (B=1.75, 95% CI 0.27 to 3.24). The majority of respondents (n=1335, 96.4%) were confident about their doctor’s expertise in terms of COVID-19 diagnosis and treatment, which was positively associated with less distress caused by the outbreak (B=–7.84, 95% CI –14.58 to –1.11). CONCLUSIONS The findings highlight the effect of COVID-19 on mental health during the nationwide lockdown among the general population in Vietnam. The study provides useful evidence for policy decision makers to develop and implement interventions to mitigate these impacts. CLINICALTRIAL

scholarly journals Exposure of Petrol Station Attendants and Auto Mechanics to Premium Motor Sprit Fumes in Calabar, Nigeria

2009 ◽  
Vol 2009 ◽  
pp. 1-5 ◽  
Author(s):  
N. E. Udonwa ◽  
E. K. Uko ◽  
B. M. Ikpeme ◽  
I. A. Ibanga ◽  
B. O. Okon
Keyword(s):  
General Population ◽  
Potential Risk ◽  
Venous Blood ◽  
Population Based ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Petrol Station ◽  
Risk Of Exposure ◽  
Structured Questionnaire

A population-based-cross-sectional survey was carried out to investigate the potential risk of exposure to premium motor spirit (PMS) fumes in Calabar, Nigeria, among Automobile Mechanics (AM), Petrol Station Attendants (PSA) and the general population. Structured questionnaire was administered on the randomly chosen subjects to elicit information on their exposure to PMS. Duration of exposure was taken as the length of work in their various occupations. Venous blood was taken for methaemoglobin (MetHb) and packed cells volume (PCV). Mean MetHb value was higher in AM (7.3%) and PSA (5.8%) than in the subjects from the general population (2.7%). PCV was lower in PSA (30.8%), than AM (33.3%) and the subjects from the general population (40.8%). MetHb level was directly proportional, and PCV inversely related, to the duration of exposure. The study suggested increased exposure to petrol fumes among AM, PSA, and MetHb as a useful biomarker in determining the level of exposure to benzene in petrol vapour.

scholarly journals HIV-1 seroprevalence in the general population of Salvador, Bahia State, Northeast Brazil

2007 ◽  
Vol 23 (1) ◽  
pp. 25-32 ◽  
Author(s):  
Inês Dourado ◽  
Craig A. Milroy ◽  
Marco Antônio Gomes Mello ◽  
Geraldo Argolo Ferraro ◽  
Humberto Castro-Lima Filho ◽  
...  
Keyword(s):  
General Population ◽  
Minimum Wage ◽  
Family Income ◽  
Dna Amplification ◽  
Income Group ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Subtype B ◽  
Wide Range ◽  
Hiv 1

To estimate HIV-1 seroprevalence in the general population of Salvador, Bahia, Brazil, we conducted a cross-sectional survey of 3,437 residents from 1998 to 2000. Subjects were drawn from 30 sentinel areas representing a wide range of living conditions. Plasma samples were screened for HIV-1 antibodies by ELISA and confirmed by immunofluorescent assay. Subtype determination by HMA was performed after proviral DNA amplification. Phylogenetic analysis using parsimony was performed with the neighbor-joining method. Overall HIV-1 seroprevalence was 0.55% (19/3,446): 0.8% for men and 0.36% for women. Seroprevalence was higher in the 31-45-year age group (1%) and among persons with family income less than twice the minimum wage (0.78%) as compared to 0.33% for the higher income group. Syphilis was detected in 37% of HIV seropositive individuals. Phylogenetic inferences identified 10 samples as subtype B in the env region and 2 samples with Benv/Fgag/Fpol and Fenv/Bgag. Age > 30 years, male gender, and income < 2 times the minimum wage were identified as risk factors for HIV-1 infection. Extrapolating the proportion of seropositive individuals to Salvador, the number of HIV-1 infected individuals was estimated at 13,750.

The impact of an ostomy on older colorectal cancer patients: a cross-sectional survey

2016 ◽  
Vol 32 (1) ◽  
pp. 89-94 ◽  
Author(s):  
N. M. Verweij ◽  
M. E. Hamaker ◽  
D. D. E. Zimmerman ◽  
Y. T. van Loon ◽  
F. van den Bos ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Cancer Patients ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Colorectal Cancer Patients ◽  
The Impact

scholarly journals Acceptance Rates and Beliefs toward COVID-19 Vaccination among the General Population of Pakistan: A Cross-Sectional Survey

2021 ◽  
Author(s):  
Farah Yasmin ◽  
Waleed Asghar ◽  
Maryam Salma Babar ◽  
Hiba Khan ◽  
Shoaib Ahmad ◽  
...  
Keyword(s):  
General Population ◽  
Cross Sectional Study ◽  
Vaccine Hesitancy ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
The Public ◽  
Polio Vaccination ◽  
Acceptance Rates ◽  
To Receive ◽  
Do So

Developing countries like Pakistan have previously suffered from barriers to acceptance of vaccination by the public because of financial and belief barriers. This study aims to explore these beliefs and highlight concerns regarding vaccine hesitancy in the general population of Pakistan since they are a hindrance to an effective coronavirus disease-19 (COVID-19) immunization in the country. A cross-sectional study was performed involving 1,778 participants from all four provinces of Pakistan. Results from the study showed more than half of the participants to be unsure of the safety (50%) and efficacy (51%) of the vaccine, whereas 42% were concerned about the side effects of the vaccine. About 72% of the respondents planned to get vaccinated, whereas 28% refused to do so. Internationally made imported vaccines were more trusted by the participants. Forty-four percent of the participants agreed to receive the vaccine upon recommendation from a physician. Lastly, participants who believed in the efficacy of the polio vaccination also considered the COVID-19 vaccine to be safe and effective.

scholarly journals Knowledge and awareness of precision medicine among dental students

2020 ◽  
Vol 11 (SPL4) ◽  
pp. 642-647
Author(s):  
Bipin M ◽  
Jeevitha M ◽  
Kavitha S
Keyword(s):  
Precision Medicine ◽  
Dental Students ◽  
Individual Variability ◽  
Medical Field ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Study Population

Precision medicine is an emerging approach for the treatment of diseases and prevention that takes into account individual variability in genes, environment and lifestyle of a person. Although the term precision medicine is relatively new, the concept has been a part of healthcare for many years. This study focuses especially to evaluate the knowledge on characteristics of precision medicine among dental students. The aim of this study is to analyse the knowledge and awareness of Precision medicine among dental students. A descriptive cross-sectional survey was conducted among dental students through a self-administrated questionnaire. The responses had been collected and statistically analysed. 61% of the study population were aware of Precision medicine and surprisingly, 82% of the respondents came across this term precision medicine. This study concludes that the dental students were aware of the term precision medicine, but they were not well aware of the role of precision medicine in the medical field.

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