scholarly journals Microencapsulation of Crude Folic Acid Extract from Chayote (Sechium edule Jacq. Swartz) with Ionic Gelation Method

2019 ◽  
Vol 16 (1) ◽  
pp. 1
Author(s):  
Johana Novita Paulina Purba ◽  
Herla Rusmarilin ◽  
Zulkifli Lubis
Keyword(s):  
Antioxidant Activity ◽  
Folic Acid ◽  
Sodium Alginate ◽  
Acid Content ◽  
Room Temperature ◽  
Ionic Gelation ◽  
Acid Extract ◽  
Sechium Edule ◽  
Cacl2 Concentration

Chayote is a plant which grow and develop throughout the year, contains of  93 mcg/100g folic acid. The aim of this research was to determine the ratio of sodium alginate with pectin and CaCl2 concentration coating to produce microcapsules of crude folic acid extract. Four phases of study was done, namely the manufacture of folic acid extract, manufacture of microcapsules with ionic gelation, analysis of folic acid content in the microcapsules, and the analysis of folic acid after storage of one week. Folic acid extract was made by maceration using alcohol 70% at pH 6, preparation of the microcapsules was using sodium alginate with pectin and folic acid was analysed using HPLC. Folic acid extract showed antioxidant activity of 98,1% with folic acid of 0,16 mg/kg. Microencapsulation of folic acid extract results showed the highest antioxidant activity was formed in alginate ratio of  70% to 30% pectin and CaCl2 concentration of 0.1 M i.e.  62.77 mg/kg. Folic acid is an antioxidant, highest antioxidant value folic acid was analyzed,  treatment was in alginate ratio of 70% to 30% pectin and CaCl2 concenration at 0.1 M i.e. 3.06 mg/kg, after one week at room temperature is became 2.39 mg/kg. 

scholarly journals Folic acid content and antioxidant activity of different types of beers available in Hungarian retail

2017 ◽  
Vol 54 (5) ◽  
pp. 1158-1167 ◽  
Author(s):  
Dániel Koren ◽  
Csaba Orbán ◽  
Nóra Galló ◽  
Szilárd Kun ◽  
Beáta Vecseri-Hegyes ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Folic Acid ◽  
Acid Content ◽  
Different Types

Sodium alginate assisted construction of ZnSnO 3 microspheres enhanced HCHO sensing performance under UV illumination at room temperature

2019 ◽  
Vol 14 (14) ◽  
pp. 1381-1384
Author(s):  
Jie Chen ◽  
Zhihua Ying ◽  
Peng Zheng ◽  
Rongfa Gao ◽  
Jinbang Mei
Keyword(s):  
Sodium Alginate ◽  
Room Temperature ◽  
Uv Illumination ◽  
Sensing Performance

Antioxidant activity of cookiessupplemented with sugarbeet dietary fiber

2011 ◽  
pp. 151-157 ◽  
Author(s):  
Marijana B. Saka ◽  
Julianna F. Gyura ◽  
Aleksandra Mišan ◽  
Zita I. Šereš ◽  
Biljana S. Pajin ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Shelf Life ◽  
Dietary Fiber ◽  
Wheat Flour ◽  
Room Temperature ◽  
Antioxidant Activities ◽  
Radical Scavenging Activity ◽  
Antioxidant Properties ◽  
Radical Scavenging ◽  
Functional Characteristics

The antioxidant activity of cookies prepared by the addition of sugarbeet dietary fibers was investigated in order to estimate their influence on functional characteristics and shelf-life of cookies. Treated fiber (TF) was obtained from sugarbeet by extraction with sulfurous acid (75 °C at pH = 5.7during 60 min) and treatment with hydrogen peroxide (20 g/LH2O2 at pH = 11 during 24 h). The fiber obtained was dried (80 °C), ground and sieved. TF was investigated in comparison with commercially available Fibrex®. The cookies were prepared by the addition of 0, 7, 9 and 11% of sugarbeet dietary fiber as a substitute for wheat flour in the formulation of cookies. The antioxidant properties of cookies were tested every 7 days using a DPPH (1,1-diphenyl-2-picrylhydrazyl) radical scavenging activity test during 6 weeks of storage at room temperature (23 ± 1 ºC). The obtained results indicated that substitution of wheat flour with Fibrex® in the formulation of cookies upgraded the antioxidant activity, i.e. the functional characteristics of Fibrex®-enriched cookies and could prolong their shelf-life. In contrast, TF did not increase the antioxidant activity of TF-enriched cookies. The better antioxidant activities of Fibrex®-enriched cookies could be attributed to the presence of ferulic acid.

scholarly journals FORMULATION AND CHARACTERIZATION OF TIMOLOL MALEATE-LOADED NANOPARTICLES GEL BY IONIC GELATION METHOD USING CHITOSAN AND SODIUM ALGINATE

2019 ◽  
pp. 48-54 ◽  
Author(s):  
RISA AHDYANI ◽  
LARAS NOVITASARI ◽  
RONNY MARTIEN
Keyword(s):  
Particle Size ◽  
Zeta Potential ◽  
Sodium Alginate ◽  
Release Kinetics ◽  
In Vitro Release ◽  
Entrapment Efficiency ◽  
Polydispersity Index ◽  
Ionic Gelation ◽  
Timolol Maleate ◽  
Optimum Formula

Objective: The objectives of this study were to formulate and characterize nanoparticles gel of timolol maleate (TM) by ionic gelation method using chitosan (CS) and sodium alginate (SA). Methods: Optimization was carried out by factorial design using Design Expert®10.0.1 software to obtain the concentration of CS, SA, and calcium chloride (CaCl2) to produce the optimum formula of TM nanoparticles. The optimum formula was characterized for particle size, polydispersity index, entrapment efficiency, Zeta potential, and molecular structure. Hydroxy Propyl Methyl Cellulose (HPMC) K15 was incorporated into optimum formula to form nanoparticles gel of TM and carried out in vivo release study using the Franz Diffusion Cell. Results: TM nanoparticles was successfully prepared with concentration of CS, SA, and CaCl2 of 0.01 % (w/v), 0.1 % (w/v), and 0.25 % (w/v), respectively. The particle size, polydispersity index, entrapment efficiency, and Zeta potential were found to be 200.47±4.20 nm, 0.27±0.0154, 35.23±4.55 %, and-5.68±1.80 mV, respectively. The result of FTIR spectra indicated TM-loaded in the nanoparticles system. In vitro release profile of TM-loaded nanoparticles gel showed controlled release and the Korsmeyer-Peppas model was found to be the best fit for drug release kinetics. Conclusion: TM-loaded CS/SA nanoparticles gel was successfully prepared and could be considered as a promising candidate for controlled TM delivery of infantile hemangioma treatment.

Folic Acid Content of Milk and Milk Substitutes

PEDIATRICS ◽  
1963 ◽  
Vol 32 (3) ◽  
pp. 463-464
Author(s):  
A. LEONARD LUHBY ◽  
JACK M. COOPERMAN
Keyword(s):  
Folic Acid ◽  
Acid Content ◽  
Present Situation ◽  
Cow’S Milk ◽  
Accurate Assessment ◽  
Cow's Milk ◽  
Milk Substitutes

The "folic acid" content of cow's milk, as listed in the report of the Committee on Nutrition (Pediatrics, 31:329, 1963) is probably too low, as pointed out by Drs. Naiman and Oski. We would agree that these figures should be withdrawn until a more accurate assessment can be made. We are, however, less certain than they appear to be, that the L. casei assay, ascorbate-protected, will provide the information desired, i.e., the true total folate content of foodstuff biologically available to the human. For an understanding of the present situation, it is necessary to review briefly certain pertinent developments in this field.

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