scholarly journals NERIUM OLEANDER: IT’S APPLICATION IN BASIC AND APPLIED SCIENCE: A REVIEW

Author(s):  
Saabiya Farooqui ◽  
Tulika Tyagi

Nerium oleander is an important medicinal plant in Indian folk medicine. It is a potentially lethal plant in many cases and poisoning is reported in tropical and subtropical parts of the world as well as a number of suicidal cases are also prevalent in South Asian countries, especially in India and Sri Lanka. All parts of the plant are toxic and contain a variety of cardiac glycosides which includes neriin, oleandrin, cardenolides, gentiobiosyl and odoroside. This plant species also produce secondary metabolites such as alkaloids, flavonoids and steroids which have pharmacological applications. The important pharmacological activities are antibacterial, anthelmintic, anti-inflammatory, hepatoprotective, immunopotential, anti-pyretic, antioxidant, antifungal, anticancer and anti-HIV activity. This review describes the evidence-based information regarding pharmacological activity as well as phytochemicals of this plant.

2017 ◽  
Vol 14 (2) ◽  
pp. 63-77 ◽  
Author(s):  
MA Hamid ◽  
MNA Siddiky ◽  
MA Rahman ◽  
KM Hossain

The present study attempts to examine the scenario of buffalo production in Bangladesh. The buffalo plays a very important role in the South Asian region which constitutes 77.5% of world buffalo population. This region has a great biodiversity in buffalo germplasm, including the world famous source promising buffaloes Murrah and Nili-Ravi - renowned for high milk production potential. It is estimated that about 96.05 % of Asia and 93.19 % of world buffalo milk are produced in South Asian countries. Besides, buffalo milk in South Asian countries is around 54.95 % of the total milk production. The India and Pakistan share 67.99% and 23.96%, of world buffalo milk production respectively. About 71.4% of world buffalo meat is produced in South Asian countries. Although buffalo is an integral part of livestock production system in South Asian countries, it has never been addressed in Bangladesh and always neglected despite their important role in the national economy. In Bangladesh, the total buffalo population are 1.464 million heads that are managed in household subsistence farming as well as extensive free range (Bathan) farming in saline coastal region that are used as a draught animal and partially for milk and meat production. The contribution of buffalo in total milk and meat production in Bangladesh is only 2.0% and 0.94%, respectively. This review has tried to unearth the present scenario of buffalo production in Bangladesh, describing the benefits and values of buffalo milk and meat, advantages of buffalo husbandry over cattle, constraints in buffalo production and recommendations for buffalo development in Bangladesh.SAARC J. Agri., 14(2): 63-77 (2016)


2021 ◽  
Vol 1 (4) ◽  
pp. 250-252
Author(s):  
Suman K. Jha ◽  
Sabin Chaulagain ◽  
Shiva Kumar Ojha ◽  
Angela Basnet Neela Sunuwar ◽  
Akanchha Khadka

Organophosphate compounds are chemicals containing central phosphate molecules with alkyl or aromatic substituent’s. They occur in diverse forms and are used as pesticides, herbicides, nerve agents, etc. Organophosphate compounds are frequently used as pesticides in agrarian communities all across the world. South Asian countries such as Nepal use vast quantities of Organophosphate compounds for pest control in agriculture. Therefore, accidental and suicidal ingestion of Organophosphate compound poisoning has been common especially among the agricultural rural communities. Apart from muscarinic, nicotinic and central nervous system effects in rare instances, Organophosphate compounds are known to cause pancreatitis.


2022 ◽  
Vol 18 ◽  
Author(s):  
Sanjay Kumar ◽  
Shiv Gupta ◽  
Varsha Rani ◽  
Priyanka Sharma

Background: Pyrazole scaffolds have gained importance in drug discovery and development for various pharmacological activities like antiviral, antifungal, anticancer, antidepressant, anti-inflammatory, antibacterial, etc. Additionally, the pyrazole moiety has shown potent anti-HIV activity as a core heterocycle or substituted heterocycles derivatives (mono, di, tri, tetra, and fused pyrazole derivatives). To assist the development of further potential anti-HIV agents containing pyrazole nucleus, here we have summarized pyrazole containing anti-HIV compounds that have been reported by researchers all over the world for the last two decades. Objective: The present review concentrates on an assortment of pyrazole containing compounds, particularly for potential therapeutic activity against HIV. Methods: Google Scholar, Pubmed, and SciFinder were searched databases with ‘‘pyrazol’’ keywords. Further, the year of publication and keywords ‘‘Anti-HIV’’ filter was applied to obtain relevant reported literature for anti-HIV agents containing pyrazole as a core or substituted derivatives. Results: This review article has shown the comprehensive compilation of 220 compounds containing pyrazole nucleus and possessing anti-HIV activity by sorting approximately 40 research articles from 2001 to date. 1-(4-Benzoylpiperazin-1-yl)-2-(4-fluoro-7-(1H-pyrazol-3-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl)ethane-1,2-dione (13), 3-(3-(2-(4-benzoylpiperazin-1-yl)-2-oxoacetyl)-4-fluoro-1H-pyrrolo[2,3-c]pyridin-7-yl)-1H-pyrazole-5-carboxamide (31), 3-(3-(2-(4-benzoylpiperazin-1-yl)-2-oxoacetyl)-4-fluoro-1H-pyrrolo[2,3-c]pyridin-7-yl)-1H-pyrazole-5-carboxamide (88), 3-cyanophenoxypyrazole derivative (130), and 4-(4-chlorophenyl)-5-(4-methyl-5-((4-nitrophenyl)diazenyl)thiazol-2-yl)-3-phenyl-5,6-dihydro-4H-pyrazolo[4,3-d]isoxazole (178) were the most potent mono-, di-, tri-, tetra-substituted, and fused pyrazole derivatives, respectively, which have shown potent anti-HIV activity among all the described derivatives as compared with standard anti-HIV drugs. Conclusion: This review article provides an overview of the potential therapeutic activity of pyrazole derivatives against HIV that will be helpful for designing pyrazole containing compounds for anti-HIV activity.


Energies ◽  
2020 ◽  
Vol 13 (21) ◽  
pp. 5776
Author(s):  
Rashiqa Abdul Salam ◽  
Khuram Pervez Amber ◽  
Naeem Iqbal Ratyal ◽  
Mehboob Alam ◽  
Naveed Akram ◽  
...  

India, Pakistan, and Bangladesh (IPB) are the largest South Asian countries in terms of land area, gross domestic product (GDP), and population. The growth in these countries is impacted by inadequate renewable energy policy and implementation over the years, resulting in slow progress towards human development and economic sustainability. These developing countries are blessed with huge potential for renewable energy resources; however, they still heavily rely on fossil fuels (93%). IPB is a major contributor to the total energy consumption of the world and its most energy-intensive building sector (India 47%, Pakistan 55% and Bangladesh 55%) displays inadequate energy performance. This paper comprehensively reviews the energy mix and consumption in IPB with special emphasis on current policies and its impact on economic and human development. The main performance indicators have been critically analyzed for the period 1970–2017. The strength of this paper is a broad overview on energy and development of energy integration in major South Asian countries. Furthermore, it presents a broad deepening on the main sector of energy consumption, i.e., the building sector. The paper also particularly analyzes the existing buildings energy efficiency codes and policies, with specific long-term recommendations to improve average energy consumption per person. The study also examines the technical and regulatory barriers and recommends specific measures to adapt renewable technologies, with special attention to policies affecting energy consumption. The analysis and results are general and can be applied to other developing countries of the world.


2013 ◽  
Vol 59 (1) ◽  
pp. 53-66 ◽  
Author(s):  
Nazeerullah Khan ◽  
Ennus Tajuddin Tamboli ◽  
V.K. Sharma ◽  
Sunil Kumar

Summary Nothapodytes nimmoniana (J. Graham) (Icacinaceae), commonly known as Amruta is found in India particularly in Maharashtra, Goa, Kerala, Assam, Jammu and Kashmir as well as Tamilnadu areas. It is an important medicinal plant, the major source of a potent alkaloid, namely camptothecin, of a wide spectrum of pharmacological activities like anti-cancer, anti-HIV, antimalarial, antibacterial, anti-oxidant, anti-inflammatory, anti-fungal and also applied in the treatment of anaemia. Camptothecin is still not synthesized, therefore, its production entirely depends on natural sources. N. nimmoniana is one such plant which yields contain camptothecin in significantly high amount. The plant is gaining international recognition due to its diversified medicinal uses. It is subjected to excessive harvest. It has been categorized as a vulnerable and endangered plant. The present review encompasses the phytochemical, analytical, pharmacological, biotechnological, and other specific aspects of N. nimmoniana.


Author(s):  
Abiche Ekalu ◽  
Rachael Gbekele-Oluwa Ayo ◽  
Habila D. James ◽  
Ibrahim Hamisu

This review aims at studying the phytochemistry and biological activities of some selected Apocynaceae plants. Eleven members of this family were reviewed for their phytochemistry and biological activities. Interestingly, the commonly isolated compounds reported from Mondia whitei (Hook.f.) Skeels, Secondatia floribunda A. DC, Carissa carandas, Tabernaemontana divaricate, Nerium oleander, Wrightia tinctoria, T. divaricate, Alstonia scholaris, Carrisa spinarum Linn, Thevetia peruviana and Caralluma lasiantha were triterpenoids, flavonoids, phytosterols, cardiac glycosides and lignans. All of them exhibited remarkable biological activities, mostly similar to each other. This review provides a detailed insight into the pharmacological activities of these selected members of this family.


2020 ◽  
pp. 1844-1854
Author(s):  
Priscilla Jayanthi Thavamany ◽  
Hong Lim Chew ◽  
Sreeramanan S. ◽  
Bee Lynn Chew ◽  
Ming-Thong Ong

Gac fruit (Momordica cochinchinensis Spreng) is an exploitable perennial dioecious fruit found commonly in Southeast Asian countries (SA). Gac fruit has been traditionally used in folk medicine due to its high medicinal and nutritive value. Generally, the aril of the fruit is used as a red colourant for cuisines and supplement for healthier vision. Gac fruit is highly rich in lycopene and β- carotene, fatty acids, vitamin E, polyphenols like phenolic acids, flavonoids and trypsin inhibitors. These compounds are linked with many important bioactivities such as provitamin A, antioxidant, antimicrobial, antiulcer and anticancer activities. This paper reviews the findings on nutritional properties, phytochemical composition and the biological activities of Gac fruit. The review has also briefly discussed the suitable conditions for the storage and utilisation of the fruit in food, beverage, nutraceutical, pharmaceutical and cosmeceutical industries


Cosmetics ◽  
2019 ◽  
Vol 6 (4) ◽  
pp. 63 ◽  
Author(s):  
Mzabri ◽  
Addi ◽  
Berrichi

The Aromatic and Medicinal Plants sector has undergone a remarkable evolution, especially during the last decade. The global market is moving more and more towards products of natural origin. Indeed, of the 4200-existing plant in Morocco, 800 are listed as aromatic and medicinal plants. Among these plants, saffron is a source of income for many areas of Morocco. Saffron, the dried stigma of the Crocus sativus flower, is considered among the main terroir products of Morocco. Saffron has accompanied all civilizations, whether for its culinary role, for its quality of dye or its ancestral virtues rooted in folk medicine. This review highlights the main components of saffron, and the pharmacological activities that result from it and make this product a serious therapeutic hope. Then, a classification of uses of saffron was carried out according to its uses, traditional, pharmaceutical, cosmetic and perfumery without forgetting its use a spice incorporated in many dishes around the world.


2000 ◽  
Vol 35 (1) ◽  
pp. 47-62
Author(s):  
P.K. Jain ◽  
Manmohan Yadav

The “Death of Distance” will be the single most important economic force shaping the society over the next half century with geography, borders and time zones becoming irrelevant with the new communication revolution. The world trade has increased manifolds since World War II and the merchandise exports have increased to about $6,000 billion today from just $50 billion in 1950 while the trade in services is increasing faster and stands at about $1,450 billion as the economies are opening up and integrating with the world economy. As evident from the experience of the countries that followed open-market and free trade policies, achieved higher growth rates in their GDP, per capita GDP, and the exports than the closed economies. As more and more countries are opening their economies and integrating with the world economy and the revolution in IT, we are heading towards a “borderless” world with free flow of trade and resources. The autarkic strategies for economic development followed by India since its independence inevitably cut the economy off from the technological advancements in rest of the world and as a result India still remains way behind the industrialised economies. Also, despite above average growth in India's GDP and exports since 1970s than the world average, India's per capita GDP is among the lowest at $370. Even the most populous country in the world, China has per capita GDP of $860. The balance-of-payments crisis in mid-1991 forced the Indian policymakers to make a paradigm shift, though under IMF-led bail out package and prescription for structural adjustments, in its economic, industrial, and trade policies more commonly known as the “economic reforms”- liberalisation and globalisation of Indian economy. While the reforms have helped overcome the liquidity crisis and the economy broadly got back to the growth charted in 1980s, yet the structural adjustments have propelled investment in non-traded goods and in buying out of well performing Indian companies and brands by the MNCs than actually increasing the gross fixed capital formation in the manufacturing sector with the modern technologies. It is under this background and the similarities in cultural, political, ethnic and alike factors among the South Asian countries, that the present paper aims at analysing and learning lessons from the progressive aspects as well as failures of India's economic reforms, while the South Asian countries emulated the same.


2018 ◽  
Vol 52 (1) ◽  
pp. 4-34 ◽  
Author(s):  
FILIPPO OSELLA

There are no reliable figures to help us measure the volume of charitable donations in South Asia but, according to the 2014 World Giving Index, Sri Lanka is ranked ninth in the world for the charitable efforts of its citizens, while other South Asian countries figure in the top 75 out of 135 countries surveyed. According to the same index, India comes first in the world for the overall number of people donating money to charities and volunteering for social causes; Pakistan is ranked sixth for the number of charitable donations; India, Pakistan, and Bangladesh are within the top ten countries for the number of people who have ‘helped a stranger’ in the 12 months prior to the survey. According to a 2001 survey by the Sampradaan Centre for Indian Philanthropy, among members of the A–C socio-economic classes, 96 per cent of respondents donated annually an average of Rs 1,420. The total amount donated was Rs 16.16 billion. Two surveys conducted in West Bengal and Sri Lanka suggest that South Asians across the social spectrum contribute readily to charity.


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