scholarly journals Lean Concept Implementation Practices in Small and Medium Scale Pharmaceutical Industry- A Case Study

Author(s):  
Ravi Nagaich

Abstract: This paper describes an exploratory study of lean techniques and an extant of its implementation in a pharmaceutical industries. The main purpose of this paper is, at how much extant adoption of lean techniques and elimination of wastage and non-value added activities in a pharmaceutical industries. A questionnaire survey is prepared to know the extent of lean techniques implementation. Questionnaire survey send to the respondents of various department (production and planning, human resources, quality and control, transportation, inventory control etc.) of an organization and asked to rate the each of these areas. This study also inspect the drivers and barriers that affect the adoption of lean techniques. The mean value for each area is obtain after calculations on SPSS and statistical analyses were performed for each area. Further, this study also examined different subjects related with lean techniques adoption for example its comprehension among the respondent organization, its advantages and impediments, the techniques and tools used, etc. The outcomes from this study also revealed the hindrance that forestall or postpone the lean execution. The main obstacles in adoption of lean technology are the absence of understanding lean ideas and shop floor representative’s attitude. Keywords: lean manufacturing, lean barriers, SPSS, mean score, driving forces

Author(s):  
Vipul Deshpande

Abstract: Lean manufacturing has been one of the most standard method in the manufacturing and service industry for elimination of waste. Every manufacturing industry has to put in continuous effort for its survival in the current impulsive and competitive economy. The purpose of this paper is to investigate the adoption of lean manufacturing tools and techniques in the manufacturing industries. This paper is based on actual implementation of lean manufacturing techniques. It focuses on the execution of flow from the start until the end of the implementation, types of analysis and tools applied, evaluation methods and how the industry benefited from the implementation. In this case study we particularly focused on Shop floor management, Quality Management (QM), Supplier and Customer Management (SCM) and Workforce Management (WM). After going through various testing on implementation of Lean Manufacturing principles in Micro Small medium Enterprise (MSME), researcher studied thoughts of some author where they discussed pragmatic problems they overcome while implementing lean principles in developing economies MSME. At the end, the result shows that there is monthly increment in capital productivity and labour productivity. And decrement in inhouse rejection, breakdown hours and customer complaint from the implementation of lean.


Author(s):  
Mohammed Abdul Rahman ◽  
Raghunatha Rao D ◽  
Vasantha L

The present study is aimed to study and analyze the true and pseudo Cholinesterase levels in the subjects exposed to pesticides during short term by intentional or accidental intake and long term exposure due to their occupation were studied at Department of Biochemistry, SVS medical college and hospital mahbubnagar district. Whole blood cholinesterase levels and Pseudo cholinesterase levels were estimated. 150 people were taken as controls who had no medical illness and a total number of 300 cases of pesticide poisoning were selected, aged between 20 to 55 years, which consist of 150 acute poisoning and 150 chronic poisoning subjects in Mahbubnagar district, were taken as case study, the detailed case history and the type of organophosphorus pesticide taken were recorded. Mean and standard deviation (S.D) of all variables were calculated and compared with those of controls. Statistical significance was assessed and P-value <0.05 were considered significant.           During acute poisoning the mean value of Whole blood cholinesterase/True cholinesterase (U / L) in acute poisoning cases on first day was 1.267± 0.612 on 3th day was 1.651±0.647, on 7th day was 2.221±0.684 and at the end of 6 months was 3.970±0.404.The difference between the study group and control group (4.0 ± 0.39) was found to be statistically significant in1st, 3rd, 7th day but not significant at the end of 6 months. The mean value of serum cholinesterase/pseudo cholinesterase (U/L) in acute poisoning cases on first day was 2213.05 ± 1749.81, on 3th day was 2862.3 ± 2025.6, on 7th day was 4008.4 ± 2355.9 and at the end of 6 months was 7708.34 ± 880.72.The difference between the study group and control group (7991.97 ± 1276.5) was found to be statistically significant in1st, 3rd, 7th day but not significant at the end of 6 months. During chronic poisoning (exposure) the mean value of Whole blood cholinesterase (U/L) in controls is 4.0 ± 0.39 as compared to 3.019 ± 0.848 in cases of chronic poisoning. The difference between the study group and control group was found to be statistically significant. The mean value of serum cholinesterase/pseudo cholinesterase (U/L) in controls was 7991.97 ± 1276.5 as compared to 6214 ± 1189 in cases of chronic poisoning. The difference between the study group and control group was found to be statistically significant.


2021 ◽  
Vol 11 (3) ◽  
pp. 7069-7074
Author(s):  
M. Masmali

The lean manufacturing concept is a systematic minimization of waste and non-value activities in production processes introduced by the Toyota production system. In this research, lean manufacturing is implemented in a cement production line. Value Stream Mapping (VSM) is applied to give a clear picture of the value chain in cement production processes and to highlight the non-value-added in the shop floor. To begin, the existing VSM is constructed based on the information and data gathered during visiting and observing the manufacturing process in the firm. As a result, the excess inventory between workstations was identified as a major waste generation, hence, the proposed VSM conducts further improvement and makes action plans to alleviate the unwanted activities. Then, the takt time to ensure smooth material flow and to avoid any occurring delay or bottleneck in the production line was figured out. The supermarket pull-based production control is suggested to be adopted in the future map. Two pull production strategies are selected in this case. The first is applying the Kanban system to control the level of inventory between workstations. The other is the CONWIP approach to control the amount of work in process to the entire production line. The outcome of the proposed models indicates a decrease of the none-value time from 23 days in the current state to about 4 and 2 days in Kanban and CONWIP systems respectively, so the CONWIP was suggested as most efficient. Some suggestions for further research are also mentioned.


Author(s):  
V. Saravanan ◽  
S. Nallusamy ◽  
Abraham George

Productivity is an important parameter for all small and medium scale manufacturing industries. Lean manufacturing emerged as production strategy capable of increasing productivity by identifying and eliminating non value added activities. This article deals with productivity improvement in a pre-assembly line of gearbox manufacturing company with a case study using lean concepts like process flow chart, process Gantt chart and time study. This paper illustrates using a case study on how a value stream mapping has to be carried out in a planet carrier pre-assembly line. Value stream mapping and work standardization are the key tools used in lean manufacturing and lean transformation. It makes the process smoother, helps in reduction of lead time and ultimately increasing the productivity. From the observed results it was found that, the productivity has been increased from 7 pieces to 10 pieces in the first step assembly when the proposed VSM was implemented. The second step processing time was reduced by the execution of proposed value stream mapping with TAKT time of 126 minutes and 165 minutes of processing time for demand of 10 pieces were achieved and the overall processing time has been reduced by about 24%.


KIRYOKU ◽  
2018 ◽  
Vol 2 (1) ◽  
pp. 18
Author(s):  
Dyah Prasetiani

(Title: Improving The Capabilities Of Agency Through Media Kanji Game Online) Japanese has several types of letters namely hiragana, katakana, kanji, and romaji. Each letter has its own uniqueness. For foreign learners, kanji is considered the most difficult. The results of interviews on the third semester students who followed the Kanji Shochukyu course showed that students often have difficulty in memorizing kanji, often forget the shape so that they are not able to write kanji correctly, and are often confused between read On and Kun. To overcome student difficulties in memorizing kanji, the author tries to use kanji media online game. The method used is experiment with experiment class and control class. The instrument used is postes. The result of the postes shows that the mean value of the experimental class is 82.5 while the control class is 70.1. Keywords: kanji; game online


Author(s):  
Orlando Roque Da Silva ◽  
Alessandro Marco Rosini ◽  
Arnoldo J H Guevara ◽  
Angelo Palmisano ◽  
Delvio Venanzi

Lean Six Sigma is a management focused on quality and productive performance in operating systems. This article discusses the foundations of this methodology through of two different conceptions of management, Lean Manufacturing and Six Sigma. First of the article explain the DMAIC (define measure, analyze, improve and control) and their respective phases, after the Lean philosophy with the sipoc and value stream mapping techniques. The article aims to show integration of these two conception and their results. The methodology consisted in a theory was based on a literature search an exploratory research which consisted of three case studies in differences companies located in Sorocaba, São Paulo. In this article studies the applying of Lean Six Sigma and its results.


1985 ◽  
Vol 104 (1) ◽  
pp. 159-163 ◽  
Author(s):  
J. S. Tindal ◽  
L. A. Blake ◽  
A. D. Simmonds ◽  
I. C. Hart

ABSTRACT Six rumen-fistulated, overnight-fasted, female British Saanen goats were used. In preliminary experiments on two of the goats, evidence was obtained that inflation of a balloon with water in the cranial sac of the rumen was accompanied by inhibition of GH release. In a definitive series of experiments on the other four goats (one goat on 1 day = one experiment), a total of 96 experiments were carried out, 48 of which were balloon inflations with 2·5 litres water at 37 °C in the cranial sac of the rumen for 40 min and 48 were control experiments on alternate days. It was found that the mean plasma GH concentration of the samples taken at the end of the 40-min inflation period was significantly (P < 0·05) lower than the mean value of the samples taken at the start of inflation. Mean control values at the start and finish of inflation were not significantly different. There were no significant differences between mean plasma insulin concentrations at the start and finish of inflation in experimental and control groups. It is concluded that distension of the cranial rumen in the goat is a signal which can inhibit the release of GH. J. Endocr. (1985) 104, 159–163


2018 ◽  
Vol 4 (2) ◽  
pp. 211-218
Author(s):  
Wulansari Wulansari ◽  
Ani Margawati ◽  
Rita Hadi W

Background: Depression is one of the most common psychosocial problems in the elderly. The incidence of depression in the elderly is greater in the elderly living in the social service unit than the elderly in the community. Management of depression in the elderly should be more emphasized on interventions that focus on the individual needs of the biopsychosocial and spiritual aspects. Brain gym therapy and Benson relaxation are considered appropriate in decreasing depression.Objective: This study was to determine the effect of brain exercise and Benson relaxation on the level of depression in elderly in the elderly social service unit.Methods: This was a quasy experimental study with pretest posttest control group design. Fifty-six elderly included in this study, which 28 assigned in the experiment and control group. The depression level was assessed using Geriatric Depression Scale (GDS). Wilcoxon and Mann-Whitney test were used for data analyses.Results: The study showed that the mean GDS score in the experiment group before the intervention was 7.21, while the mean value of GDS in the control group was 6.64. The mean value of GDS in the experiment group after the intervention was 5.04 and the mean in control group was 6.18. There was a significant difference of GDS score between experiment and control group with p-value of 0.021 (<0.05).Conclusion: There was a significant effect of brain gymnastics and Benson relaxation therapy in reducing depression in elderly. brain gymnastic therapy and benson relaxation can be one of independent nursing interventions as an effort to improve care for elderly groups.


2021 ◽  
Vol 9 (3) ◽  
pp. 97-114
Author(s):  
Reem Alkurdi ◽  
Sharif Alghazo

This study aims to investigate English as a Foreign Language (EFL) teachers’ misbehaviours in class and their students’ reactions to these misbehaviours. Towards this end, 60 classroom observations of six English language teachers (N=10 each) were conducted at a public school in Jordan. Moreover, a survey was used to elicit 201 students’ reactions to their teachers’ misbehaviours by gauging their satisfaction with the teachers’ communication styles. Finally, the teacher participants were interviewed in order to more deeply understand why such misbehaviours occurred. Analysis of the data is grounded in the Expectancy Violation Theory. The results revealed that when the mean value of teachers’ communication style was more than 3 on a 5-point Likert Scale, the students often perceived their teachers as being positive, and the students compensated most of their teachers’ misbehaviours. However, when the mean value was below 3, the teachers were perceived as being negative, and the students reciprocated for most of the misbehaviours. The results also showed that the students are more tolerant towards their teachers’ misbehaviours as long as the teacher is perceived to be positive. The study provides insights into understanding the student-teacher relationship in EFL classes.


Author(s):  
Reem M. Soliman ◽  
Mohamed B. Hamza ◽  
Rasha M. El-Shafiey ◽  
Hesham A. Elserogy ◽  
Nabil M El-Esawy

Background: There are few biomarkers that can be easily accessed in clinical settings and may reflect refractory Th2-eosinophlic inflammation and remodeling of the asthmatic airways. Serum periostin may be one such biomarker to aid our understanding of the patho-bio-physiology of asthma and exercise induced asthma. The aim of the study is to explore the relationship between serum periostin level and exercise induced bronchoconstriction in asthmatic children. Materials and Methods: This cross-sectional study was carried out on (90) children both sexes aged from 6 to 15 years including, (60) children with bronchial asthma and (30) children were enrolled as control group in the period from January 2018 to January 2019. Patients were randomly classified into two groups: I) Patient group: divided into 2 groups according to standardized treadmill exercise challenge test: Group A: (30) asthmatic children with positive test. Group B: (30) asthmatic children with negative test. II-Control group: (30) children apparently healthy with no personal or family history of asthma. All children were subjected to the following Investigations: Chest x-ray, pulmonary functions tests (FEV1 & PEFR) except controls, Laboratory investigations as CBC and Serum periostin level. Results: The mean values of both the percentage of PEFR and FEV1 after exercise in group A were significantly lower than those in group B and the percentage of PEFR and FEV1 after exercise in each group were significantly lower than the percentage before exercise in the same group. The mean value of eosinophilic count in group A was significantly higher than (group B and control group) and the mean value of eosinophilic count in group B was significantly higher than control group. The mean value of serum level of periostin in group A was significantly higher than (group B and control group), however, there was no significant difference between group B and control group as regard to serum level of periostin. Chest tightness, cough and wheezes after exercise and eosinophilic count in patients with high serum periostin level were significantly higher than patients with low serum periostin level, and both PEFR and FEV1 after exercise in patients with high serum periostin level were significantly lower than patients with low serum periostin level. Also the normal serum periostin levels vary among different age groups. Conclusion: Serum periostin level can be considered as a useful biomarker for diagnosis of Exercise induced bronchospasm (EIB) in asthmatic children especially when lung function test cannot be done However, cautious is required in evaluating serum periostin levels in children because it varies with age.


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