scholarly journals GC-MS Analysis of Bioactive Compounds and Phytochemical Evaluation of the Ethanolic Extract of Gomphrena globosa L. Flowers

2020 ◽  
Vol 10 (2) ◽  
pp. 53-58
Author(s):  
Azmat Unnisa Esmat ◽  
Sirisha Mittapally ◽  
Safiya Begum
Keyword(s):  
Bioactive Compounds ◽  
Ethanolic Extract ◽  
Pharmacological Activities ◽  
Ms Analysis ◽  
Gomphrena Globosa ◽  
Whole Plant ◽  
Docosanoic Acid ◽  
Phytochemical Compounds ◽  
Phytochemical Constituents ◽  
Anti Inflammatory

Gomphrena globosa (L.) has high medicinal values. All parts are been used as folk medicines. The extract of whole plant / flowers has shown different phytochemical constituents with various clinical properties. These phytochemicals recognised are responsible for various activities such as anti-inflammatory, anticancer, antibacterial, analgesic and cytotoxic. The ethanolic extract of Gomphrena globosa L. flowers of biochemical test indicates the presence of sterols, triterpenoid, tannins, phenols and flavonoids, and on GC-MS analysis it has shown 11 phytochemical compounds with different pharmacological activities. The major bioactive compounds are Docosanoic Acid, Docosyl Ester (25.404%) and Hexatriacontane (24.324%), has proven anti-inflammatory activity. Keywords: Gomphrena globose L., phytochemical constituents, GC-MS and anti-inflammatory.

scholarly journals Phytochemicals and GC–MS analysis of bioactive compounds present in ethanolic leaves extract of Taraxacum officinale (L).

2019 ◽  
Vol 9 (1) ◽  
pp. 90-94
Author(s):  
P Sasikala ◽  
S Ganesan ◽  
T Jayaseelan ◽  
S Azhagumadhavan ◽  
M Padma ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Fine Powder ◽  
Ethanol Extract ◽  
Taraxacum Officinale ◽  
Phytochemical Analysis ◽  
Ms Analysis ◽  
Biological Compounds ◽  
Phytochemical Compounds ◽  
Medicinal Properties ◽  
Phytochemical Constituents

Objective: To identify the phytochemical constituents present in ethanolic leaves extract of Taraxacum officinale (T. o) and to elucidate the bioactive compounds. Methods: The fresh leaves of T. officinale (1000g) were shade dried at room temperature for 30 days and the dried leaves were made into a fine powder. The ethanolic leaves extract obtained was dried with help of desiccator and rotatory evaporator. The dried samples tested for phytochemical analysis and bioactive compounds profiling through GC-MS analysis. Results: The phytochemical screening studies showed presence of alkaloids, flavonoids, phenol, cardiac glycosides and anthraquinones. in the leaves extract of T. officinale. GC-MS analysis showed 10 essential bioactive compounds and it revealed the presence of significant anticancer, Antimicrobial  and antidiabetic compounds. Conclusions: The ethanol extract of T. o possess the most important phytochemical compounds and it has various  medicinal  properties to cure dangerous diseases and disorders. Keywords: Taraxacum officinale, Phytochemicals analysis, GC–MS analysis, Biological compounds.

scholarly journals GC–MS study on ethanolic extract of Vetiveria lawsonii root

2016 ◽  
Vol 5 (3) ◽  
pp. 108-111
Author(s):  
P Ramachandran ◽  
◽  
Viji Saral Elezabeth D Elezabeth D ◽  
Keyword(s):  
Mass Spectrometer ◽  
Bioactive Compounds ◽  
Ethanolic Extract ◽  
Pharmacological Activities ◽  
Ms Analysis

The present study was focused to scrutinize the presence of phytoconstituents in the ethanolic extract of Vetiveria lawsonii root using GC-MS. The GC-MS analysis of Vetiveria lawsonii root was performed using Agilent 6890-JEOL GC-Mate-II Mass Spectrometer. The result of the study showed the presence of six bioactive compounds in the ethanolic extract. On account of this investigation, we can conclude that the ethanolic extract of Vetiveria lawsonii root shows the presence of 6 bioactive phytoconstituents. This might be the cause for the various pharmacological activities of the plant.

scholarly journals GC-MS analysis of bioactive compounds from the whole plant ethanolic extract of Evolvulus alsinoides (L.) L

2013 ◽  
Vol 52 (2) ◽  
pp. 1212-1217 ◽  
Author(s):  
Duraisamy Gomathi ◽  
Manokaran Kalaiselvi ◽  
Ganesan Ravikumar ◽  
Kanakasabapathi Devaki ◽  
Chandrasekar Uma
Keyword(s):  
Bioactive Compounds ◽  
Ethanolic Extract ◽  
Ms Analysis ◽  
Evolvulus Alsinoides ◽  
Whole Plant

Brassica oleracea var. capitata f. alba: a review on its botany, traditional uses, phytochemistry and pharmacological activities.

2021 ◽  
Vol 21 ◽  
Author(s):  
Lipi Rani Ray ◽  
Muhammad Shaiful Alam ◽  
Md. Junaid ◽  
Sakia Ferdousy ◽  
Rasheda Akter ◽  
...  
Keyword(s):  
Brassica Oleracea ◽  
Pharmacological Effects ◽  
Pharmacological Activities ◽  
Cruciferous Vegetable ◽  
Traditional Uses ◽  
White Cabbage ◽  
Whole Plant ◽  
Wide Range ◽  
Phytochemical Compounds ◽  
Phytochemical Constituents

Background: Brassica oleracea var. Capitata F. Alba (white cabbage) is a cruciferous vegetable which used as a vegetable and traditional medicine all over the world. Different preparation from several parts of the plant - roots, shoots, leaves and the whole plant are used to treat a wide range of diseases including diabetes, cancer, gastric, inflammation, hypertension, hypercholesterolemia, bacterial, oxidation, and obesity. Objective: The aim of the current review is to evaluate the botany, distribution, traditional uses, phytochemistry and pharmacological activities of B. oleracea var. Capitata. Moreover, this review will guide to fill the existing gaps in information and highlight additional research prospects in the field of phytochemistry and pharmacology. Method: Various resources including research papers, review papers, books and reports were collected to obtain over all information of Brassica oleracea var. Capitata, which were obtained by an online search of worldwide-accepted scientific databases. Phytochemical constituents’ structures were drawn by ChemDraw software. Results: About 72 isolated phytochemical compounds of B. oleracea var. Capitata have been collected from different article, which included different type of compounds such as alkaloids, flavonoids, organic acids, glucosinolates, steroids, hydrocarbons etc. Crude extracts and phytoconstituents of B. oleracea var. Capitata have various pharmacological effects including antidiabetic, anticancer, antihypertensive, anticholesterolemic, antioxidant, anti-inflammatory, antibacterial, antiobesity, anticoagulant & hepatoprotective. We have enlisted all these pharmacological data along with all the phytochemical constituents of Brassica oleracea var. Capitata. Conclusion: The study was focused on the traditional uses, pharmacological activities and phytochemistry of Brassica oleracea var. Capitata and the findings indicating that B. oleracea var. Capitata is an important medicinal plant which shows several pharmacological effects. We hope our review on this plant will provide more basic and useful information and fill some research gap for further investigation and drug design. Despite we found some important traditional uses and pharmacological activities of Brassica oleracea var. Capitata there are insufficient work found in the field of phytochemical activities.

scholarly journals GC-MS Analyses of Bioactive Compounds of Ethanolic Seed Extract of Elaeocarpus serratus

2019 ◽  
Vol 11 (1) ◽  
Author(s):  
DH Geetha ◽  
Indhiramuthu Jayashree ◽  
M Rajeswari
Keyword(s):  
Bioactive Compounds ◽  
Ethanolic Extract ◽  
Seed Extract ◽  
Ms Analysis ◽  
Phytochemical Constituents ◽  
Traditional Practitioners ◽  
Novel Drug ◽  
Area Percentage

The present investigation was carried out to determine the possible bioactive compounds of ethanolic extract of Elaeocarpus serratus (Elaeocarpaceae) has been subjected to GC-MS analysis. Thirty compounds were detected from the plant E. serratus. The highest peak area percentage of 19.12% was obtained by n-propanol (RT=3.04min.) and lowest peak area percentage of 2.34% was obtained by 1-propylthio-3,3,3-trifluoropropyl acetate (RT=11.57min.). The presence of various bioactive compounds confirms many aliments by traditional practitioners. However, isolation of individual phytochemical constituents may proceed to find a novel drug.

scholarly journals Pharmacological Insights into Halophyte Bioactive Extract Action on Anti-Inflammatory, Pain Relief and Antibiotics-Type Mechanisms

Molecules ◽  
2021 ◽  
Vol 26 (11) ◽  
pp. 3140
Author(s):  
Rocco Giordano ◽  
Zeinab Saii ◽  
Malthe Fredsgaard ◽  
Laura Sini Sofia Hulkko ◽  
Thomas Bouet Guldbæk Poulsen ◽  
...  
Keyword(s):  
Pain Relief ◽  
Bioactive Compounds ◽  
Biomedical Applications ◽  
Medicinal Products ◽  
Salt Tolerant ◽  
Salicornia Europaea ◽  
Pharmacological Activities ◽  
Sustainable Resources ◽  
Anti Inflammatory ◽  
Significant Attention

The pharmacological activities in bioactive plant extracts play an increasing role in sustainable resources for valorization and biomedical applications. Bioactive phytochemicals, including natural compounds, secondary metabolites and their derivatives, have attracted significant attention for use in both medicinal products and cosmetic products. Our review highlights the pharmacological mode-of-action and current biomedical applications of key bioactive compounds applied as anti-inflammatory, bactericidal with antibiotics effects, and pain relief purposes in controlled clinical studies or preclinical studies. In this systematic review, the availability of bioactive compounds from several salt-tolerant plant species, mainly focusing on the three promising species Aster tripolium, Crithmum maritimum and Salicornia europaea, are summarized and discussed. All three of them have been widely used in natural folk medicines and are now in the focus for future nutraceutical and pharmacological applications.

scholarly journals Phytochemical Analysis, Pharmacological and Safety Evaluations of Halophytic Plant, Salsola cyclophylla

Molecules ◽  
2021 ◽  
Vol 26 (8) ◽  
pp. 2384
Author(s):  
Hamdoon A. Mohammed ◽  
Mohsen S. Al-Omar ◽  
Salman A. A. Mohammed ◽  
Ahmad H. Alhowail ◽  
Hussein M. Eldeeb ◽  
...  
Keyword(s):  
Ethanolic Extract ◽  
Phytochemical Analysis ◽  
High Concentration ◽  
Halophytic Plant ◽  
Anti Oxidant ◽  
Aqueous Ethanolic Extract ◽  
Phytochemical Constituents ◽  
Anti Inflammatory ◽  
Dpph Scavenging ◽  
Anti Inflammation

Salsola cyclophylla, an edible halophyte, is traditionally used for inflammation and pain. To confirm the claimed anti-inflammatory and analgesic properties, a detailed study on respective pharmacological actions was undertaken. The activities are contemplated to arise from its phytoconstituents. The LC-MS analysis of S. cyclophylla 95% aqueous-ethanolic extract revealed the presence of 52 compounds belonging to phenols, flavonoids, coumarins, and aliphatics class. A high concentration of Mn, Fe, and Zn was detected by atomic absorption spectroscopic analysis. The ethyl acetate extract showed the highest flavonoid contents (5.94 ± 0.04 mg/g, Quercetin Equivalents) and Fe2+-chelation (52%) potential with DPPH radicals-quenching IC50 at 1.35 ± 0.16 mg/mL, while the aqueous ethanolic extract exhibited maximum phenolics contents (136.08 ± 0.12 mg/g, gallic acid equivalents) with DPPH scavenging potential at IC50 0.615 ± 0.06 mg/mL. Aqueous ethanolic extract and standard quercetin DPPH radicals scavenging’s were equal potent at 10 mg/mL concentrations. The aqueous ethanolic extract showed highest analgesic effect with pain reduction rates 89.86% (p = 0.03), 87.50% (p < 0.01), and 99.66% (p = 0.0004) after 60, 90, and 120 min, respectively. Additionally, aqueous ethanolic extract exhibited the highest anti-inflammation capacity at 41.07% (p < 0.0001), 34.51% (p < 0.0001), and 24.82% (p < 0.0001) after 2, 3, and 6 h of extract’s administration, respectively. The phytochemical constituents, significant anti-oxidant potential, remarkable analgesic, and anti-inflammatory bioactivities of extracts supported the traditionally claimed anti-inflammatory and analgesic plant activities.

scholarly journals A Review on Ethnopharmacological Applications, Pharmacological Activities, and Bioactive Compounds ofMangifera indica(Mango)

2017 ◽  
Vol 2017 ◽  
pp. 1-24 ◽  
Author(s):  
Meran Keshawa Ediriweera ◽  
Kamani Hemamala Tennekoon ◽  
Sameera Ranganath Samarakoon
Keyword(s):  
Amino Acids ◽  
Bioactive Compounds ◽  
Mangifera Indica ◽  
Fruit Peel ◽  
Pharmacological Activities ◽  
Phytochemical Constituents ◽  
Pharmacological Potential ◽  
Diverse Plant ◽  
Different Parts ◽  
Comprehensive Study

Mangifera indica(family Anacardiaceae), commonly known as mango, is a pharmacologically, ethnomedically, and phytochemically diverse plant. Various parts ofM. indicatree have been used in traditional medicine for the treatment of different ailments, and a number of bioactive phytochemical constituents ofM. indicahave been reported, namely, polyphenols, terpenes, sterols, carotenoids, vitamins, and amino acids, and so forth. Several studies have proven the pharmacological potential of different parts of mango trees such as leaves, bark, fruit peel and flesh, roots, and flowers as anticancer, anti-inflammatory, antidiabetic, antioxidant, antibacterial, antifungal, anthelmintic, gastroprotective, hepatoprotective, immunomodulatory, antiplasmodial, and antihyperlipemic. In the present review, a comprehensive study on ethnopharmacological applications, pharmacological activities, and bioactive compounds ofM. indicahas been described.

scholarly journals Evaluation Of Antioxidant, Antidiabetic, Anti-Inflammatory And Anticancer Activities Of Delonix Regia Flower Extracts

2021 ◽  
Vol 11 (6) ◽  
pp. 103-115
Author(s):  
Benoite. T ◽  
Nora Vigasini K
Keyword(s):  
Side Effects ◽  
Cell Lines ◽  
A549 Cell ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Ethanolic Extract ◽  
Alpha Amylase ◽  
Ms Analysis ◽  
Anti Inflammatory ◽  
Mcf 7

Non-communicable diseases like diabetes and cancer are the major cause of death worldwide. Various drugs are used for the treatment of these diseases. However, they cause lots of side effects. There is a need for alternate drugs with fewer side effects. Medicinal plants serve as a good source for alternate form of treatment. Therefore, in this study, ethanolic and aqueous extracts of D. regia flowers were evaluated for their antioxidant, antidiabetic, anti-inflammatory and cytotoxic activity to justify its use as a medicinal plant. Total phenol and flavonoid content of the extracts were measured. GC-MS analysis of the extracts were done to investigate the presence of various bioactive compounds. Antioxidant activity was assessed by radical scavenging and reduction assays. Antidiabetic activity was assessed by the ability of extracts to inhibit enzyme alpha amylase. Anti-inflammatory activity was evaluated by membrane stabilization activity. Anticancer activity against MCF-7 and A549 cell lines were measured by the MTT assay.The ethanolic extract contained more phenols (282.940.80 mgGAE/g) and flavonoids (140.912.27 mgQE/g). GC-MS analysis showed the presence of compounds belonging to fatty acids, alkanes, phenols and organic alcohols. The aqueous extract showed strong superoxide radical scavenging activity with a low IC50 of 39.35±0.74 µg/mL. The ethanolic extract showed higher ferric reducing power with an IC50 of 59.65±0.28µg/mL. Ethanolic extract was more potent in inhibiting alpha amylase with a low IC50 value of 47.14±0.6 µg/mL. Ethanolic extract also showed maximum inhibition of 88.86±0.1% against heat induced lysis of cell membrane. Both extracts affected the proliferation of MCF-7 and A549 cell lines at 160 µg/mL. The results of the present study support the use of D. regia flower as a potential source of bioactive phytochemicals and can be used as a plant-based antioxidant, antidiabetic, anti-inflammatory and anticancer agent.

scholarly journals Review Based Upon Ayurvedic and Traditional Uses of Cinnamomum tamala (Tejpatta)

2021 ◽  
Vol 68 (2) ◽  
Author(s):  
Shifali Thakur ◽  
Gitika Chaudhary
Keyword(s):  
Chemical Constituents ◽  
Bioactive Constituents ◽  
Pharmacological Activities ◽  
The Past ◽  
Cinnamomum Tamala ◽  
Medicinal Use ◽  
Phytochemical Compounds ◽  
Phytochemical Constituents ◽  
Herbal Plant ◽  
Flavoring Agent

Cinnamomum tamala is an evergreen plant native to Sri Lanka and India. This herbal plant is commonly called Indian cassia, Tejpatta and Indian bay leaf. There are many bioactive constituents isolated from plant Cinnamomum tamala. Leaves of the plant possess aromatic fragrance and are also utilized as a flavoring agent. It is used in food curry, pickles and other spices. Besides food application, the leaves have also been used for curing a number of ailments. All parts of the plant possess many major bioactive chemical constituents like cinnamaldehyde, trans-cinnamaldehyde, 3,4,5,7- tetrahydroxyflavone, 3,3,4,5,6- pentahydroflavone (non-glycoside compounds), kaempferol, eugenol, etc. These phytochemical compounds have many pharmacological activities such as anticancer, antidiabetic, antimicrobial, hepatoprotective, antidiarrheal and immunomodulatory. In the past time, it is also considered for medicinal use. Their medicinal use was also mentioned in the literature of ayurveda, yunani and other traditional systems of medicine. Due to aromatic fragrance, it is also utilized in the perfume industry. The major aim of this review is to give a brief knowledge about the plant Cinnamomum tamala based on their phytochemical constituents, ayurvedic view, folk view and pharmacological application.

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