scholarly journals Drug utilization evaluation of antibiotics in district hospital Rudraprayag

2018 ◽  
Vol 8 (6) ◽  
pp. 87-90 ◽  
Author(s):  
Kanishk Kala ◽  
Rupinder Kaur Sodhi ◽  
Upendra Kumar Jain

Drug utilization is very important for antibiotics as they are widely used in hospitals and their in appropriate use may lead to resistance. To check this irrational use of antibiotics and promote rational use the present retrospective study was conducted to access drug utilization evaluation of antibiotics in in patient department of District Hospital Rudraprayag for a period of three months. Overall 126 patients records were encountered in the study in which male female ratio .was 1 2. Prominent age range was 21-40. Overall 1064 drugs were prescribed average number of drug per prescription was 8.44. Percentage of drug by generic name was 33. Percentage of antibiotic prescribed was 82.74. Percentage of drugs with EDL was 66.16. Study results revealed poly-pharmacy, brand prescribing as common trends. Study showed need to promote prescribers to follow generic prescribing and use injectable and antibiotics rationally to prevent development of resistance in hospital and community. Keywords: Antibiotic resistance, Drug utilization, Antibiotics

2017 ◽  
pp. 50-55
Author(s):  
Duc Luu Ngo ◽  
Tu The Nguyen ◽  
Manh Hung Ho ◽  
Thanh Thai Le

Background: This study aims to survey some clinical features, indications and results of tracheotomy at Hue Central Hospital and Hue University Hospital. Patients and method: Studying on 77 patients who underwent tracheotomy at all of departments and designed as an prospective, descriptive and interventional study. Results: Male-female ratio was 4/1. Mean age was 49 years. Career: farmer 44.2%, worker 27.2%, officials 14.3%, student 7.8%, other jobs 6.5%. Respiratory condition before tracheotomy: underwent intubation 62.3%, didn’t undergo intubation 37.7%. Period of stay of endotracheal tube: 1-5 days 29.2%, 6-14 days 52.1%, >14 days 18.7%. Levels of dyspnea before tracheotomy: level I 41.4%, level II 48.3%, level III 0%, 10.3% of cases didn’t have dyspnea. Twenty cases (26%) were performed as an emergency while fifty seven (74%) as elective produces. Classic indications (37.7%) and modern indications (62.3%). On the bases of the site, we divided tracheostomy into three groups: high (0%), mid (25.3%) and low (74.7%). During follow-up, 44 complications occurred in 29 patients (37.7%). Tracheobronchitis 14.3%, tube obstruction 13%, subcutaneous empysema 10.4%, hemorrhage 5%, diffcult decannulation 5.2%, tube displacement 3.9%, canule watery past 2.6%, wound infection 1.3%. The final result after tracheotomy 3 months: there are 33 patients (42.9%) were successfully decannulated. In the 33 patients who were successfully decannulated: the duration of tracheotomy ranged from 1 day to 90 days, beautiful scar (51.5%), medium scar (36.4%), bad scar (12.1%). Conclusions: In tracheotomy male were more than female, adult were more than children. The main indication was morden indication. Tracheobronchitis and tube obstruction were more common than other complications. Key words: Tracheotomy


2014 ◽  
Vol 4 (7) ◽  
pp. 530-533
Author(s):  
D Ghartimagar ◽  
A Ghosh ◽  
K Gautam ◽  
S Thapa ◽  
SR Shrestha ◽  
...  

Background: Pilomatricoma is a slow-growing, asymptomatic tumour originating from outer sheath cells of hair follicle. In this study, we describe the clinical presentation and histopathological features of pilomatricoma. Materials and Methods: This was a hospital based retrospective study carried out in all patients who were diagnosed as pilomatricoma over a period of January 2001 to December 2013. The study was done in department of pathology, Manipal Teaching Hospital, Nepal. Results: A total of 21 cases of pilomatricoma were reported with age range of 9-53 years (mean age 23.7) and male female ratio of 1:1.1. The most common site of occurrence was neck and preauricular region. The size of the tumour ranged from 0.3 to 4.7cm with a mean of 1.2cm. Multiple occurrences were seen in 3 patients and ossifying pilomarticoma was seen in 4 cases. Conclusion: Pilomatricoma is a benign skin neoplasm of hair follicle matrix cells. Calcification is a common finding while dystrophic ossification also can occur in the tumour. Histopathology gives the definite diagnosis as fine needle aspiration cytology and clinical impression may be misleading. DOI: http://dx.doi.org/10.3126/jpn.v4i7.10293 Journal of Pathology of Nepal (2014) Vol. 4, 530-533


2020 ◽  
Vol 32 (1) ◽  
pp. 1-4
Author(s):  
Md Mahmud Ul Huda ◽  
Sajed Abdul Khaleque ◽  
Mohammad Habibullah ◽  
Zakia Farhana

Introduction: Retinal diseases especially those due to diabetes and AMD are coming up as important causes of blindness and visual impairment. Our study is to evaluate the frequency and pattern of retinal diseases in ophthalmic outpatient department of a district hospital in Bangladesh. Materials and Methods: A total number of 173 referred new retina cases were reviewed at outpatient department of the 250 beded General Hospital, Jamalpur, Bangladesh, between February 2017 and November 2017. Data was analyzed according to age, sex and clinical diagnoses and detailed fundus evaluation done with binocular indirect ophthalmoscope and slit lamp using 20D and 90D lenses respectively. Results: Out of 7164 new patients,of whom 173 patients were (2.42%) presented with retinal diseases.139 patients were reviewed and followed up. Male: female ratio was 1.24:1. Out of 139 patients 77 (55.4%) were males and 62 (44.6%) females with a peak age group of 41-50 years. Diabeticrelated retinal conditions were 36 cases (25.9%), the most common cause.16 (44.44% of total DR) patients had CSME and 5(14.9%) had ADED. Diabetic retinopathy 36 cases (25.9%), Chorioretinitis 20 cases (14.4%), ARMD 11 cases (7.9%), and Optic atrophy 10 cases (7.2%). Conclusion: Retinal diseases remain an important cause of visual morbidity. There is increasing incidence of retinal blindness especially diabetic retinopathy in Bangladesh. The impression based on hospital practice is that the problem is increasing. This entails the necessity for accessible comprehensive eye care services, establishment of human resources, screening and awareness of the disease and affordable eye health policy. Medicine Today 2020 Vol.32(1): 1-4


2019 ◽  
Vol 70 (7) ◽  
pp. 2471-2476
Author(s):  
Camelia Liana Buhas ◽  
Bogdan Adrian Buhas ◽  
Lucia Georgeta Daina ◽  
Bianca Hanganu ◽  
Irina Smaranda Manoilescu ◽  
...  

Ingestion of cheap para-pharmaceuticals (such as disinfectants, deodorizing solutions, etc.) which are designed only for external use is an unfortunate habit encountered in the recent decades in the economically disadvantaged areas of Romania inhabited by poor, uninformed, and sanitary uneducated population. These para-pharmaceutical products are based on different concentrations of ethanol. Occasionally, the manufacturer modifies the product formula, or worse omits on the label that the ethanol was replaced with methanol, resulting in mass poisoning with a large number of casualties. The authors present a case of mass poisoning by methanol that occurred during one month and resulted in 40 cases of methanol intoxication. Only 5 out of the 40 victims survived the intoxication. All the dead victims underwent medico-legal autopsy which revealed only general features, liable to poisoning. The toxicological examination result was positive for methanol in all the cases. All the intoxicated victims were homeless; they were heavy ethanol consumers, especially of the product rubbing alcohol. The male: female ratio was 31:4 and the age range was between 25 and 70 years old, with an average of 50 years. All the victims were hospitalized in deep coma, showing obvious pathological changes specific to chronic ethanol consumption. Conclusions: some alcoholic para-pharmaceutical products manufactured for external use are ingested by chronic ethanol drinkers. When these products contain methanol, they can cause severe intoxication followed by an impressively large number of deaths.


2014 ◽  
Vol 8 (2) ◽  
pp. 53-55
Author(s):  
Mohammed Tanvir Jalal ◽  
Shahadot Hossain Sheikh ◽  
Md Rayhanur Rahman ◽  
Mesbah Uddin Noman ◽  
Jesmin Akhter Leena ◽  
...  

Anorectal malignancies that require abdominoperineal resection (APR) is very common. Laparoscopic APR can be a better option. Laparoscopic APR has been seldom studied. This study aims to evaluate perioperative and early postoperative outcomes of laparoscopic APRs performed for the treatment of ano-rectal carcinomas. Patients operated for ano-rectal carcinoma between June 2011 to June 2013 in Bangabandhu Sheikh Mujib Medical University (BSMMU) were observed. Demographics, tumor and procedure-related parameters, perioperative results, early postoperative outcomes and survival were observed. Total 22 patients were under went laparoscopic APR. Male: Female ratio was 15:7 (68.18%: 31.82%). Age range was from 30-65 years with a mean age of 36.55 years. Mean operation time was 165 minutes and mean post-operative hospital stay was 6.8 days. Overall complication rate was 45.45%. Laparoscopic APR is a safe, effective and technically feasible procedure. It can be a better operative procedure than open APR. DOI: http://dx.doi.org/10.3329/fmcj.v8i2.20281 Faridpur Med. Coll. J. 2013;8(2): 53-55


2016 ◽  
Vol 3 (2) ◽  
Author(s):  
Sukrita Mukherjee ◽  
Dr. Ishita Chatterjee

Cognitive style or thinking style is a term used in cognitive psychology to describe the way individuals think, perceive and remember information. The present study aims to understand the cognitive style adapted by higher secondary students. The study sample consists of 90 higher secondary school students (30 each from science, humanities and commerce background). The male female ratio was 50:50. The age range was from 16-18 years. They were all from middle socio-economic status. They were administered an adapted version of cognitive style questionnaire by Ancona, Kochan, Scully, Van maanen and Westney. The results indicate for the dimension of Sensing there was significant effect of stream of study and gender. For the Intuition dimension again there was a significant effect of stream and gender. For Perceiving dimension also there was a significant effect of stream and gender. Sensing was highest for the science stream and lowest for the Humanities. Again Intuition was highest for the Humanities stream and lowest for the Science stream. The males have always scored highest in the dimension of Perceiving than their female counterparts both in Humanities and Science stream. And the female irrespective of the stream of study has scored higher in the Intuitive dimension. The present study is helpful in the field of designing educational guidance and curriculum for the Higher Secondary Students.


2015 ◽  
Vol 3 (2) ◽  
pp. 342-346
Author(s):  
Muhammad Zohaib Nawaz ◽  
Muhammad Bilal ◽  
Muhammad Aamer Mehmood ◽  
Muhammad Asgher

Pakistan has a high magnitude of cancer from its independence. The burden of lymphoma cancer continues to increase in Pakistan. The low socioeconomic districts of Punjab such as those in Faisalabad most severely affected by lymphoma. The objective of this study was to analyze the lymphoma cancer registry record of patients from the districts in Faisalabad in order to achieve a net lymphoma incidence for use in raising future health program against cancer. The medical records of 110 patients registered at the Punjab Institute of Nuclear Medicine in Faisalabad were investigated. Information regarding age, gender, socioeconomic status, affected sites and cancer type were obtained. Among 110 cases of lymphoma cancer, the male: female ratio was 3:1, with an age range of 5-85 years. Of the 110 patients, 74% were male and 26% were female. Similar to the subtype distribution of lymphoma in the different areas of Faisalabad and its surroundings, Non-Hodgkin’s lymphoma (NHL) was more frequent, 74 cases (67%) than Hodgkin’s disease (HD), 36 cases (33%).The leading cancers were breast 36% (n=248), lymphoma 16% (n=110), and prostate cancer 10% (n=68). The growing burden of cancer especially lymphoma in Faisalabad is extremely alarming. Since the current work was an initial investigation, it could play a leading role in prevention and future planning regarding the battle against lymphoma in Pakistan.Int J Appl Sci Biotechnol, Vol 3(2): 342-346 DOI: http://dx.doi.org/10.3126/ijasbt.v3i2.12756 


2021 ◽  
pp. 25-29
Author(s):  
Sandip Kumar Ghosh ◽  
Ajay Halder ◽  
Arnab Mishra ◽  
Prabir Biswas

INTRODUCTION: The appendix, another named vermiform appendix (from the Latin ward-appendix means “dangling” + “vermis”+ “form” i.e.-dangling worm-shaped thing) is a diverticulum of caecum and marks the beginning of the colon in the conuence of taenias. The appendix is posteromedially attached to the caecum, about 2cm below the ileocecal junction. Taking into account that often the appendix is a mobile structure, the medical 9 importance of its relative position has been questioned by some authors. In general, however some authors describe a signicant relationship between its location and sign and symptoms of acute appendicitis. OBJECTIVES:1.To study the commonest position of appendix seen intraoperatively among the patients with acute appendicitis present in Emergency and OPD of Burdwan Medical College. 2.To identify the commonest position responsible for of gangrenous appendix and appendicular perforation. 3.To identify various signs and symptoms according to their different anatomical position and correlation with intraoperative ndings MATERIALS AND METHODS: This is a Prospective Observational Study in Burdwan Medical college and hospital ,May 2019 to July 2020 on 100 patients. All willing patients in Emergency and OPD of BMCH with acute and recurrent appendicitis who underwent surgery are included in this study. RESULTS: rd th Appendicitis is commonest during 3 decade (43%) followed by 4 decade (36%).Appendicitis is slightly commoner in females with male: female ratio 1:2.4..The most common position of appendix in our study is pelvic position.


Blood ◽  
2013 ◽  
Vol 122 (21) ◽  
pp. 5245-5245
Author(s):  
Mervat Mattar ◽  
Nihad Tawfik ◽  
Noha Elhosseiny ◽  
Mohamed Morad

Abstract Objective We report 90 cases of Polycythemia Vera ( PV )during the period between 2003 and 2013 followed up in an adult Cairo  hematology reference center Results Among 90 PV cases registered between 2003 and 2013, sixty eight cases (75.6%) of  whompresented in the last three years alone.  The age range was between 19 and 72 years with a mean of 53.5 years and 25 cases ( 27.78%) presented in the age group between 50-55 years.   Male : female ratio was 1.3:1.Fifty per cent of patients were urban while 50% lived in the country. Symptoms included headache (24 cases) (26.67%), tinnitus (7 cases) (7.78%), fatigue (14 cases) (15.56%), weight loss (5 cases)(5.56%), fever and sweating( 7 cases)( 7.78%) , bone or joint pains (22 cases)(24.44%), parasthesias (13 cases)(14.44%), pruritis(7 cases) (7.78%)  or abdominal discomfort (16 cases)(17.78% (Fig 1) Figure (1) : Incidence Of Symptoms Among 90 Egyptian PV Cases Severity of symptoms was assessed by a simple score of zero (none), +1 (mild),+ 2 (moderate) and +3 (severe) (table1) Nine cases (10%) presented by venous thrombosis , 4 of whom had portal vein thrombosis (4.44%) Cerebro-vascular strokes were noted in 5 cases (5.56%) and acute myocardial infarction in 2 cases (2.22%). Splenomegaly was noted in 29 cases (32.22%) of cases and hepatomegaly in 13 cases (14.44%). Associated conditions included hypertension in 24 cases (26.67%), gastrointestinal symptoms in 16 cases(17.78%) Diabetes mellitus in 15 cases (16.67%),Hepatitis C virus infection in 6 cases ( 6.67%), Hepatitis B in 2 cases ( 2.26%), coronory heart disease in 5 cases (5 .56%) and renal problems in 3 cases ( 3.33%). Bleeding episodes included 6 (6.67%) GI and 3(3.33%) gum bleeds. Familial MPN, Cancer prostate, intestinal Schistosomiasis   and post-liver transplant done post- hepatitis C virus cirrhosis were reported in one case each. Twenty two cases(24.44%) were controlled on Hydroxyuria only,16 cases 17.78%) on venesection plus hydroxyuria,16 cases(17.78%) on venesection only. Progression  was noted in 13 cases (14.44%) with marrow fibrosis in five cases (5.56%) and 14 cases (15.56%) were lost to follow-up. Mortality was seen in 10% (nine cases). Conclusion PV among Egyptians may have distinct presentations regarding incidence, age and  presentation.Simpler methods of symptom severity assessments may be more suitable for Egyptian patients. Disclosures: Mattar: Novartis, BMS, Amgen: Honoraria.


Pathogens ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 684
Author(s):  
Shun-Xian Zhang ◽  
David Carmena ◽  
Cristina Ballesteros ◽  
Chun-Li Yang ◽  
Jia-Xu Chen ◽  
...  

Cryptosporidium spp., Entamoeba histolytica, Giardia duodenalis, and Blastocystis sp. infections have been frequently reported as etiological agents for gastroenteritis, but also as common gut inhabitants in apparently healthy individuals. Between July 2016 and March 2017, stool samples (n = 507) were collected from randomly selected individuals (male/female ratio: 1.1, age range: 38‒63 years) from two sentinel hospitals in Tengchong City Yunnan Province, China. Molecular (PCR and Sanger sequencing) methods were used to detect and genotype the investigated protist species. Carriage/infection rates were: Blastocystis sp. 9.5% (95% CI: 7.1–12.4%), G. duodenalis 2.2% (95% CI: 1.1–3.8%); and E. histolytica 2.0% (95% CI: 0.9–3.6%). Cryptosporidium spp. was not detected at all. Overall, 12.4% (95% CI: 9.7–15.6) of the participants harbored at least one enteric protist species. The most common coinfection was E. histolytica and Blastocystis sp. (1.0%; 95% CI: 0.3–2.2). Sequence analyses revealed that 90.9% (10/11) of the genotyped G. duodenalis isolates corresponded to the sub-assemblage AI. The remaining sequence (9.1%, 1/11) was identified as sub-assemblage BIV. Five different Blastocystis subtypes, including ST3 (43.7%, 21/48), ST1 (27.1%, 13/48), ST7 (18.8%, 9/48), ST4 (8.3%, 4/48), and ST2 (2.1%, 1/48) were identified. Statistical analyses confirmed that (i) the co-occurrence of protist infections was purely random, (ii) no associations were observed among the four protist species found, and (iii) neither their presence, individually or jointly, nor the patient’s age was predictors for developing clinical symptoms associated with these infections. Overall, these protist mono- or coinfections are asymptomatic and do not follow any pattern.


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