scholarly journals The Polyphony of the Silent: The Specifics of Dostoevsky’s Philosophical Discourse

2021 ◽  
Vol 26 (3) ◽  
pp. 375-391
Author(s):  
Alexandr B. Krinitsyn

The article describes the phenomenon of silence in Dostoevskys later prose. Philosophical, plot-forming and psychological aspects of silence are looked at. A confessional type of monologue is defined as a discursive genre, with specific roles of the speaker and his silent listeners, whose predominance in Dostoevskys prose lets the author of the article adjust the notion of polyphony and dialogue within the context of Dostoevskys poetics. The conventionality of the other in the confessional type of monologue is proved by the absence of the completing functions in listeners. In most cases Dostoevskys later works retain some rudimental forms of frantic dialogue while the role of specific monologue discourse, caused and conditioned by silence, is increasing. By semantics and function types of silence in Dostoevsky fall into three groups: 1) the underground silence as expression of human disunity in the epoch of universal solitude; 2) role silence of listeners in the discursive genre of confessional monologue; 3) sacred silence of Christ indicating transition to a new higher level of communication

2020 ◽  
Vol 9 (1) ◽  
pp. 83-102 ◽  
Author(s):  
Kiera Lindsey

This article discusses a recent art project created by the Wiradjuri and Kamilaroi artist Jonathon Jones, which was commissioned to commemorate the opening of the revitalized Hyde Park Barracks in Sydney in early 2020. Jones’ work involves a dramatic installation of red and white crushed stones laid throughout the grounds of the barracks, merging the image of the emu footprint with that of the English broad convict arrow to ‘consider Australia’s layered history and contemporary cultural relations’. This work was accompanied by a ‘specially-curated programme’ of performances, workshops, storytelling and Artist Talks. Together, these elements were designed to unpack how certain ‘stories determine the ways we came together as a nation’. As one of the speakers of the Artist Talk’s programme, I had a unique opportunity to experiment with what colleagues and I have been calling ‘Creative histories’ in reference to the way some artists and historians are choosing to communicate their research about the past in ways that experiment with form and function and push disciplinary or generic boundaries. This article reflects upon how these two distinct creative history projects – one visual art, the other performative – renegotiate the complex and contested pasts of the Hyde Park Barracks. I suggest that both examples speak to the role of memory and creativity in shaping cultural responses to Australia’s colonial past, while Jones' programme illustrates how Indigenous artists and academics are making a profound intervention into contemporary understandings of how history is ‘done’ in Australia.


Diversity ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 361
Author(s):  
Lei Wu ◽  
Xinqiang Xie ◽  
Jumei Zhang ◽  
Yu Ding ◽  
Qingping Wu

Healthy longevity is associated with many factors, however, the potential correlation between longevity and microbiota remains elusive. To address this, we explored environmental microbiota from one of the world’s longevity townships in China. We used 16S rRNA gene high-throughput sequencing to analyze the composition and function of water microbiota. The composition and diversity of water microbiota significantly differed between the towns. Lactobacillus, Streptococcus, Bacteroides, Faecalibacterium, and Stenotrophomonas were only dominant in Xinpu, a town with an exceptionally high centenarian population. Several biomarkers were identified, including Flavobacterium, Acinetobacter, Paracoccus, Lactobacillales, Psychrobacter, Bacteroides, Ruminococcaceae, and Faecalibacterium, and these shown to be responsible for the significant differences between towns. The main species contributing to the differences between towns were Cyanobacteria, Cupriavidus and Ralstonia. Based on KEGG pathways showed that the predicted metabolic characteristics of the water microbiota in Xinpu towns were significantly different to those of the other towns. The results revealed significant differences in the composition and diversity of water microbiota in the longevity township. These findings provide a foundation for further research on the role of water microbiota in healthy longevity.


Author(s):  
Nick Ceramella

<strong><strong></strong></strong><p align="LEFT">I<span style="font-family: DejaVuSerifCondensed; font-size: small;">n the Introduction to this article, I deal with the importance of speaking one’s </span>own language as a way to assert one’s identity. Then I pass on to the evolution of the English language from its start as Old English, spoken by only a few thousand Angles and Saxons.</p><p align="LEFT"><span style="font-family: DejaVuSerifCondensed; font-size: small;">I remark how, at fi rst, it was contaminated by thousands of </span>Latin, French and Scandinavian words, of which contemporary English still bears many clear traces, but nobody has ever thought that English was ever in danger of disappearing. By contrast, in the long run, it became the mother tongue of the speakers in comparatively newly founded countries, such as the USA, Australia, and New Zealand, and owing to the spread of the British Empire, it has dramatically increased its appeal becoming the most spoken and infl uential language in the world. Thus, according to some linguists, it has led several languages virtually to the verge of disappearance. Therefore, I argue whether English has really vampirised them, or has simply contributed to make people understand each other, sometimes even in the same country where lots of diff erent tongues are spoken (e.g. Nigeria).</p><p align="LEFT">It is self-evident that English has gradually been taking the role of a common unifying factor in our globalised world. In this view, I envisage a scenario where English may even become the offi cial l anguage o f the E U with the c ontributions &amp; coming, though in varying doses, from all the speakers of the other EU languages.</p>


2007 ◽  
Vol 11 (1) ◽  
pp. 25-29
Author(s):  
Krisna Yetti

AbstrakContinuous Ambulatory Peritoneal Dialysis (CAPD) merupakan salah satu terapi pengganti pada Penyakit Ginjal Tahap Akhir (PGTA). Empat area yang menjadi tanggung jawab perawat CAPD adalah predialisis, rawat inap, sebelum dan selama pelatihan CAPD, serta pada saat pasien di rumah. Merujuk pada empat peran perawat, yaitu sebagai praktisi, pengelola, peneliti, dan pendidik, maka peran perawat CAPD mempunya peran dan fungsi yang berbeda pula pada masing-masing area ini. Tujuan utama peran dan fungsi perawat di setiap area ini adalah agar layanan keperawatan yang diterima oleh pasien menjadi prima. Pada artikel ini dibahas peran perawat sebagai praktisi dan pengelola pelayanan keperawatan. Sedangkan dua peran lagi yaitu pendidik dan peneliti tidak dibahas. AbstractContinuous Ambulatory Peritoneal Dialysis (CAPD) is one of replacement therapy of End Stage Renal Disease (ESRD). CAPD nurse takes the responsibility in four areas. Those are pre-dialysis stage, during hospitalization, before and during peritoneal dialysis training, and patient at home. Refer to the roles of the nurses, as a care provider, manager, educator and researcher, CAPD nurse has a comprehensible role and function. This comprehensible role and function is also applied in this each area in order to get the better quality of life of the CAPD patients. In this article the role of care provider and manager are discussed. However, the other two, educator and researcher roles are not discussed.


2019 ◽  
Vol 3 (1) ◽  
pp. 22
Author(s):  
Sri Hartati ◽  
Muhamad Rezi

<p><em>Alquran, as the Holy Book of Moslems, contents all of the guidance for humans in their life. Those guidances are written in global, not in detail. On the other hand, humanity consists of physics and psychics, and all need guidance from Allah in the Holy Qur’an. One of the directions is about psychology that is defined as a science of mental activities of a living organism. According to the Holy Qur’an, there are five terms of psychological aspects, and they are al-nafs, al-aql, al-qalb, al-ruh, and al-fithrah. All of these we call them the inner dimensions of human or psychology.</em><em> </em><em>Each of these aspects has a similarity to understand psychology. But in other case has different meaning and function.</em><em></em></p>


Author(s):  
Juliann B. Tefft ◽  
Jennifer L. Bays ◽  
Alex Lammers ◽  
Sudong Kim ◽  
Jeroen Eyckmans ◽  
...  

The Notch pathway regulates complex patterning events in many species and is critical for the proper formation and function of the vasculature. Despite this importance, how the various components of the Notch pathway work in concert is still not well understood. For example, NOTCH1 stabilizes homotypic endothelial junctions, but the role of NOTCH1 in heterotypic interactions is not entirely clear. NOTCH3, on the other hand, is essential for heterotypic interactions of pericytes with the endothelium, but how NOTCH3 signaling in pericytes impacts the endothelium remains elusive. Here, we use in vitro vascular models to investigate whether pericyte-induced stabilization of the vasculature requires cooperation of NOTCH1 and NOTCH3. We observe that both pericyte NOTCH3 and endothelial NOTCH1 are required for stabilization of the endothelium. Loss of either NOTCH3 or NOTCH1 decreases accumulation of VE-cadherin at endothelial adherens junctions and increases the frequency of wider, more motile junctions. We found that DLL4 was the key ligand for simulating NOTCH1 activation in endothelial cells and observed that DLL4 expression in pericytes is dependent on NOTCH3. Altogether, these data suggest that an interplay between pericyte NOTCH3 and endothelial NOTCH1 is critical for pericyte-induced vascular stabilization.


Cells ◽  
2019 ◽  
Vol 8 (11) ◽  
pp. 1306 ◽  
Author(s):  
St. John

It is becoming increasingly apparent that cells require cooperation between the nuclear and mitochondrial genomes to promote effective function. However, it was long thought that the mitochondrial genome was under the strict control of the nuclear genome and the mitochondrial genome had little influence on cell fate unless it was extensively mutated, as in the case of the mitochondrial DNA diseases. However, as our understanding of the roles that epigenetic regulators, including DNA methylation, and metabolism play in cell fate and function, the role of the mitochondrial genome appears to have a greater influence than previously thought. In this review, I draw on examples from tumorigenesis, stem cells, and oocyte pre- and post-fertilisation events to discuss how modulating one genome affects the other and that this results in a compromise to produce functional mature cells. I propose that, during development, both of the genomes interact with each other through intermediaries to establish genomic balance and that establishing genomic balance is a key facet in determining cell fate and viability.


2017 ◽  
Vol 19 (2) ◽  
pp. 209
Author(s):  
Muhammad Djakfar

<p>Sharia economy is one of the economic system, in addition to the other two systems namely capitalist and socialist. Although the socialist system is no longer popular at the global level, but in reality the Sharia Economy system is still outdone by the secularistic capitalist system. In practice, the capitalist system contains many weaknesses so that the world community began to look for other systems as a solution, namely sharia economy. In Indonesia the development system is relatively slow, so it is necessary to optimize the role of ulama and the function of local wisdom. This is the literature research with data sources from various literature and relevant issues. The results of the study show that with its authority, contemporary ulama can perform the role as a giver of fatwas, enlighteners, thinkers and economic actors. Enlightenment can be done through religious or educational events, while business practices can be conducted in pesantren by developing businesses, all of which are part and function of local wisdom.</p><p><br />Ekonomi syariah adalah merupakan salah satu sistem ekonomi, di samping kedua sistem yang lain yakni kapitalis dan sosialis. Sekalipun sistem sosialis akhir-akhir ini tidak lagi populer di tingkat global, namun dalam kenyataan sistem ekonomi syariah masih kalah cepat dengan sistem kapitalis yang sekularistik. Dalam praktiknya, sistem kapitalis mengandung banyak kelemahan sehingga masyarakat dunia mulai mencari sistem lain sebagai solusi, yakni ekonomi syariah. Di Indonesia sistem ini perkembangannya relatif lambat sehingga perlu mengoptimalkan peran ulama dan fungsi kearifan lokal. Wacana ini merupakan penelitian pustaka dengan sumber data dari berbagai literatur dan isu yang relevan. Hasil kajian menunjukkan bahwa dengan otoritasnya, ulama kontemporer dapat melakukan peran sebagai pemberi fatwa, pencerah, pemikir dan pelaku ekonomi. Pencerahan dapat dilakukan melalui acara keagamaan atau pendidikan, sedangkan praktik bisnis dapat dilakukan di pesantren dengan mengembangkan usaha, yang semuanya itu merupakan bagian dan fungsi dari kearifan lokal.</p>


Author(s):  
Benjamin Sammons

This chapter discusses the role of the gods, with emphasis on divine intervention as a compositional device. Of the cyclic epics, the Cypria shows the greatest divine activity, with many parallels to the Iliad in the range and function of divine interventions, though the notion of a controlling “will of Zeus” added much irony to the basic scheme. However, it is the Aethiopis that shows a clearer parallel to the Iliad in its mixture of divine aid and divine conflict. The other poems of the Cycle show a much closer affinity to the Odyssey. Divine intervention is used sparingly, with relatively few gods being involved; divine conflict is less emphasized; and gods mainly serve to inspire, advise, or hinder heroes to provide direction to the narrative. Also included is a discussion of the much freer use of prophecies and omens in the Cycle as compared with Homer.


2002 ◽  
Vol 22 (15) ◽  
pp. 5367-5379 ◽  
Author(s):  
Pei-Yun Jenny Wu ◽  
Fred Winston

ABSTRACT The Saccharomyces cerevisiae SAGA complex is required for the normal transcription of a large number of genes. Complex integrity depends on three core subunits, Spt7, Spt20, and Ada1. We have investigated the role of Spt7 in the assembly and function of SAGA. Our results show that Spt7 is important in controlling the levels of the other core subunits and therefore of SAGA. In addition, partial SAGA complexes containing Spt7 can be assembled in the absence of both Spt20 and Ada1. Through biochemical and genetic analyses of a series of spt7 deletion mutants, we have identified a region of Spt7 required for interaction with the SAGA component Spt8. An adjacent Spt7 domain was found to be required for a processed form of Spt7 that is present in a previously identified altered form of SAGA called SLIK, SAGAalt, or SALSA. Analysis of an spt7 mutant with greatly reduced levels of SLIK/SAGAalt/SALSA suggests a subtle role for this complex in transcription that may be redundant with a subset of SAGA functions.


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