scholarly journals Efisiensi Mikroenkapsulasi Ekstrak Kulit Buah Naga Super Merah (Hylocereus costaricensis) Tersalut Maltodekstrin Berdasarkan Kecepatan Pengadukan

KOVALEN ◽  
2020 ◽  
Vol 6 (1) ◽  
pp. 1-8
Author(s):  
Jaya Hardi ◽  
Dian Citra ◽  
Syamsuddin ◽  
Dwi Juli Pusptasari
Keyword(s):  
Antioxidant Activity ◽  
Particle Size ◽  
Free Radicals ◽  
Freeze Drying ◽  
Fruit Peel ◽  
Coating Efficiency ◽  
Dragon Fruit ◽  
Before And After ◽  
Ic50 Values ◽  
Peel Extract

Extract of super red dragon fruit peel has an antioxidant activity that can prevent free radicals from outside and its activity can be maintained by the coating of super red dragon fruit peel extract with maltodextrin The coating efficiency of super red dragon fruit peel extract with maltodextrin can be controlled with the speed of stirring during microencapsulation experiment. In order to obtain the highest microencapsulation efficiency and compare the antioxidant activity of super red dragon fruit peel extract before and after microencapsulation experiment. The study of coating efficiency has been done with microencapsulation that was carried out using the freeze-drying technique. During the microencapsulation of super red dragon fruit peel extract with freeze-drying technique, stirring speed in the microencapsulation process was 600 rpm, 800 rpm, 1000 rpm, 1200 rpm, and 1400 rpm respectively. From the microencapsulation process of super red dragon fruit peel extract coated with maltodextrin, it was obtained the highest microencapsulation efficiency at stirring speed of 800 rpm, which was 66.85% and had a particle size of 14.24 µm. It can be concluded that the antioxidant activity before and after encapsulation included a very weak category with IC50 values of 205.42 ppm for extracts and 246.32 ppm for microcapsules. Keywords: Super red dragon fruit peel, freeze-drying, microencapsulation, maltodextrin

scholarly journals Antioxidant and Anti-Hyaluronidase Activities of Dragon Fruit Peel Extract and Kaempferol-3-O-Rutinoside

2019 ◽  
Vol 30 (4) ◽  
pp. 247
Author(s):  
Liana Liana ◽  
Rizal Rizal ◽  
Wahyu Widowati ◽  
Fioni Fioni ◽  
Khainir Akbar ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Free Radicals ◽  
Human Life ◽  
Fruit Peel ◽  
Paired Samples ◽  
Dragon Fruit ◽  
Ic50 Value ◽  
Significant Difference ◽  
Ic50 Values ◽  
Peel Extract

Aging is a natural process in human life and is triggered by the presence of free radicals (ROS). The use of antioxidants from natural ingredients is one of the breakthroughs to overcome aging and counteract the harmful effects caused by the free radicals. This study aimed to determine and compare the antioxidant activity of H2O2 scavenging and hyaluronidase inhibition of red dragon fruit peel extract (DFPE) and kaempferol-3-o-rutinoside (KOR) compounds. Dragon fruit peel extract (DFPE) is obtained through extraction by maceration method using 70% ethanol solvent. The design of this study included antioxidant and anti-aging activity assay of EKBN and KOR at the series concentration of 15.63; 31.25; 62.50; 125; 250; 500 µg/mL through H2O2 scavenging, as well as the DFPE and KOR hyaluronidase inhibition assay at the series concentration of 5.21; 10.42; 20.83; 41.7; 83.33; 166.67 µg/mL. EKBN shows that the average activity of H2O2 scavenging is lower than KOR. In addition, the IC50 values of KOR for H2O2 scavenging is lower (351.46±2.30ug/mL) than DFPE (409.64±23.17ug/mL). While, KOR also has higher values of inhibitory activity than of the DFPE. However, the IC50 value of KOR for hyaluronidase inhibition activity was 84.07±10.46µg/mL, equivalent to the IC50 value of DFPE (85.32±10.24µg/mL). The presence of antioxidant and anti-aging activity in the EKBN is probably caused by betalain and the KOR compound itself contained in red dragon fruit. The results of the paired-samples T-test on antioxidant activity and anti-aging of DFPE and KOR showed non-significant difference. Thus, DFPE has an equivalent antioxidant and anti-aging through H2O2 scavenging and hyaluronidase activity as possessed by the KOR compound.

scholarly journals Mikroenkapsulasi Ekstrak Kulit Buah Naga Super Merah (Hylocereus costaricensis) pada Berbagai Massa Maltodekstrin dan Aplikasinya Sebagai Antioksidan

KOVALEN ◽  
2020 ◽  
Vol 6 (3) ◽  
pp. 191-197
Author(s):  
Sucianti ◽  
Nurhaeni ◽  
Jaya Hardi
Keyword(s):  
Freeze Drying ◽  
Ethanol Extract ◽  
Efficiency Ratio ◽  
Fruit Peel ◽  
Coating Efficiency ◽  
Dragon Fruit ◽  
Dpph Scavenging ◽  
Technique Comparison ◽  
Peel Extract

Red super dragon fruit peel (Hylocereus costaricensis) extract has capability to scavenge DPPH and the activity could be maintained by using maltodextrin as coating. The aims of the research are to determine ratio of red super dragon fruit peel ethanol extract toward maltodextrin producing microcapsule with the highest coating efficiency and DPPH scavenging content by microcapsule of red super dragon fruit peel extract. Microencapsulation was carried out using freeze drying technique. Comparison of red super dragon fruit peel extract and maltodextrin were 1: 8, 1: 10, 1: 12, and 1:14 (w / w). The results show that the highest efficiency ratio of coating extract of red super dragon fruit peel with maltodextrin was 1: 8 with percentage of 90,77%. Level of DPPH scavenging content of red super dragon fruit peel extract microcapsule with ratio of 1:8 on 5 minutes and 60 minutes each is 27.36% and 46.62%. Keywords: Hylocereus costaricensis, freeze drying, maltodextrin, microencapsulation

scholarly journals Formulasi Masker Gel Antioksidan Mengandung Ekstrak Kulit Buah Naga Merah (Hylocereus polyrhizus)

2017 ◽  
Vol 6 (1) ◽  
Author(s):  
Sunarmi Sunarmi ◽  
Susilo Yulianto
Keyword(s):  
Antioxidant Activity ◽  
Physical Stability ◽  
Fruit Peel ◽  
Dragon Fruit ◽  
Dpph Method ◽  
Before And After ◽  
The Face ◽  
Ic50 Values ◽  
High Antioxidant Activity ◽  
Dispersive Power

Abstract: Antioxidant, Red Dragon Fruit, Gel Mask. Skin is an organ that covers the entire human body, which has protection against external influences. Free radicals and the oxidation reaction can be inhibited by an antioxidant compound. Red dragon fruit peel is rarely used but has high antioxidant activity that can be used for skin care, especially facial skin. Red dragon fruit peel can be formulated into various dosage form of antioxidants for the face skin, one of which peel-off mask gel. This study aimed to test the antioxidant activity of peel-off mask gel with the active ingredient of red dragon fruit peel extracts. This research uses experimental methods. Red dragon fruit peel extracted by maceration in 70% ethanol and concentrated. Gel mask made in 3 variations extract concentration, ie formula A, B and C 0.175 g, 0.350 g and 0,700 g respectively. The physical stability test was conducted by cycling test for 6 cycles. The physical properties of the preparation were tested before and after storage include adhesion, dispersive power, pH, viscosity and time to dry. Antioxidant activity tested with DPPH method. Based on test results obtained physical stability, third-formula gel mask physically qualified and stable, except for the dispersive power. Antioxidant activity decreased after the storage. The highest activity was shown by formula C with an IC50 value of 3497.113 ppm. Based on IC50 values, this gel mask has an inactive. antioxidant activity.

scholarly journals PENGARUH RASIO PELARUT TERHADAP EKSTRAKSI DARI KULIT BUAH NAGA MERAH (Hylocereus polyrhizus)

KOVALEN ◽  
2019 ◽  
Vol 5 (3) ◽  
pp. 280-289
Author(s):  
Amalia Noviyanty ◽  
Chitra Anggriani Salingkat ◽  
Syamsiar Syamsiar
Keyword(s):  
Solvent Ratio ◽  
Fruit Peel ◽  
Extract Yield ◽  
Randomized Design ◽  
Fruit Skin ◽  
Dragon Fruit ◽  
Ic50 Value ◽  
Ic50 Values ◽  
Completely Randomized Design ◽  
Peel Extract

This study aims to determine the effect of the ratio of solvents to extract yield, phenolics total and IC50 values ​​of red dragon fruit peel and also get the optimal solvent ratio to obtain extract yield, phenolics total and the highest or best IC50 values ​​of red dragon fruit peel extracts. The solvent ratio used there are 6 levels of the ratio: 2:1; 3:1; 4:1; 5:1; 6:1 and 7:1 (v/w). The data obtained were analyzed using a Completely Randomized Design that was applied to observations of extract yield, phenolics total and IC50 values, if the treatment had a very significant or significant effect followed by continued Tukey HSD test at 1% or 5% level. The results showed that the solvent ratio very significantly affected the extract yield, phenolics total and IC50 value of red dragon fruit peel extract.  The solvent ratio of 4:1 (v/w) produced extract yield, phenolics total and IC50 values the highest or best i.e  26.22%, 71.56 ppm, and 124.62 ppm. Keywords : IC50, the red dragon fruit skin, solvent ratio, phenolics total

scholarly journals EFFECTS OF RED DRAGON FRUIT PEEL EXTRACT ADMINISTRATION ON NEUTROPHIL COUNTS FOLLOWING PERIAPICAL RADIOGRAPHY EXPOSURE

2021 ◽  
Vol 6 (2) ◽  
pp. 154
Author(s):  
Maydina Izzatul Yazidah ◽  
Didit Aspriyanto ◽  
Renie Kumala Dewi
Keyword(s):  
Free Radicals ◽  
Radiation Exposure ◽  
Cell Damage ◽  
Control Group ◽  
Fruit Peel ◽  
X Ray ◽  
Dragon Fruit ◽  
Significant Difference ◽  
Peel Extract ◽  
Periapical Radiography

Background: Radiation exposure from periapical imaging can cause cell damage in various tissues due to the formation of free radicals. Cell damage in the tissue can be observed from the number of neutrophils which are immune cells. Free radicals can be suppressed by administering exogenous antioxidants. One source of natural antioxidants is red dragon fruit, especially on its peel. Objective: To analyze the effect of periapical imaging x-ray radiation exposure after the administration of red dragon fruit peel extract on absolute neutrophil counts in mice. Method: This research was a true experimental study with a post-test only and control group design using 24 mice that were divided into 6 groups. The control group was not given any treatment while P1 to P5 group were given red dragon fruit peel extract at a dose of 100 mg/kg BW and exposed to radiation with different exposures. P1 group was exposed 1 time (0.63 mGy), P2 group was exposed 4 times (1.66 mGy), P3 group was exposed 8 times (4.37 mGy), P4 group was exposed 12 times (8.19 mGy), and group P5 was given no exposure. Results: There were changes in the number of neutrophils in all groups. The LSD Posthoc test results showed a significant difference between the control group (12.470 / mm3) and the P5 group (12.470 / mm3) compared to P3 group with 8 times exposure (40.348 / mm3). Conclusion: There is an effect of periapical radiographic x-ray radiation exposure by red dragon fruit peel extract on the absolute neutrophil count in mice. Keywords: Antioxidants, Neutrophils, Periapical Radiography, Radiation, Red Dragon Fruit Peel.

scholarly journals Daya Antioksidan Ekstrak Kulit Buah Naga Dan Sabun Ekstrak Kulit Buah Naga (Hylocereus Polyrhizuz)

2020 ◽  
Vol 6 (1) ◽  
pp. 22-25
Author(s):  
Mohamad Ikram ◽  
Nining Sugihartini ◽  
Any Guntarti
Keyword(s):  
Antioxidant Activity ◽  
Test Results ◽  
Fruit Peel ◽  
Fruit Extract ◽  
Dragon Fruit ◽  
Dpph Method ◽  
Coloring Agents ◽  
Peel Extract

Red dragon fruit peel extract contains betalain which has antioxidant activity. In addition, this extract also contains dyes that can be used as coloring agents in cosmetic preparations. The purpose of this study was to study the activity of dragon fruit peel extract and red dragon fruit peel extract soap with various concentrations. Antioxidant activity is taken by the DPPH method. The concentration of red dragon fruit peel extract in soap is 0.3; 0.6; 0.9%. Test results show red dragon fruit extract soap has lower antioxidant activity than the extract. The increased concentration of the extract caused an increase in the antioxidant activity of the red dragon fruit peel extract soap.

scholarly journals Therapy Effect of Red Dragon Fruit (Hylocereus polyrhizus) Peel Extract to Increase the Number of Sertoli Cells On BALB/c Mice (Mus musculus) Exposed to Lead Acetate

2020 ◽  
Vol 56 (2) ◽  
pp. 108
Author(s):  
Evy Wulandari ◽  
Reny I'tishom ◽  
Sri Agus Sudjarwo
Keyword(s):  
Free Radicals ◽  
Mus Musculus ◽  
Sertoli Cells ◽  
Lead Acetate ◽  
Fruit Peel ◽  
Dragon Fruit ◽  
Therapy Effect ◽  
Significant Difference ◽  
Peel Extract ◽  
Hylocereus Polyrhizus

Lead is the free radicals and heavy metals of major pollutants in the environment. Lead is toxic and cumulative. Red dragon fruit (Hylocereus polyrhizus) peel extract is a natural antioxidant. Red dragon fruit peel extract can be used to stabilize free radicals by supplementing electron deficiencies and inhibiting chain reactions. This study aimed to analyze therapy effect of red dragon fruit peel extract to increase the number of Sertoli cells on BALB/c mice (Mus musculus) exposed to lead acetate. Fourty mice were divided into 5 groups (each group consisted of 8 mice). K- group was the control group without lead acetate and dragon fruit peel extract administration, K + group was given 100 mg/KgBW lead acetate orally on the 1st day until day 14th.. P1, P2, and P3 group were continued with red dragon extract orally on the 15th day until 39th day. P1 with dose 250 mg/KgBW, P2 with dose 500 mg/KgBW, and P3 with dose 1000 mg/KgBW. The result showed significant difference (P<0.05) in the number of Sertoli cells between K+ and P1, P2, P3 group. In conclusion, dose 500 mg/kgBW of red dragon fruit peel extract can be used as the most effective therapy to increase the number of Sertoli cells on mice exposed to acetate lead.

scholarly journals Uji Aktivitas Antioksidan Body Butter Ekstrak Etanol Kulit Buah Naga Merah dengan Metode DPPH

2021 ◽  
Vol 6 (2) ◽  
pp. 178-184
Author(s):  
Repining Tiyas Sawiji ◽  
Elisabeth Oriana Jawa La
Keyword(s):  
Antioxidant Activity ◽  
Cell Damage ◽  
Pharmaceutical Preparation ◽  
Ethanol Extract ◽  
The Body ◽  
Fruit Peel ◽  
Activity Test ◽  
Dragon Fruit ◽  
Ic50 Values ◽  
Hylocereus Polyrhizus

Red dragon fruit peels (Hylocereus polyrhizus) are considered important by the community. While the red dragon fruit peel contains flavonoids, betacyanin, anthocyanin, and vitamin C which have antioxidant activity so that it can ward off free radiation and prevent cell damage. Antioxidants are molecules that can prevent the oxidation of other molecules. Antioxidants can protect the skin from various free radical cell damage. The body butter is a pharmaceutical preparation in the cosmetic field that can be used for skin health care. This study aims to determine the percentage of antioxidant activity and IC50 values in the body butter ethanol extract of red dragon fruit peels. Red dragon fruit peels were extracted first using the maceration method with 96% ethanol solvent. The antioxidant activity test was measured using UV-Vis spectrophotometry. The results showed that the antioxidant activity value of formula I obtained IC50 values (56.17 μg / mL), formula II IC50 values (88.26 μg / mL), and formula III IC50 values (146.05 μg / mL). From the results obtained, the body butter formula which has the greatest activity is the formula I (AAI = 0.7). Antioxidant activity in body butter preparations is included in the group of moderate antioxidants.

scholarly journals Antioxidant and Sunscreen Activity Purified Extract of Kenikir Leaves (ETDK) and Tampoi Fruit Peel Extract (EKBT) Nanocream

2021 ◽  
Vol 7 (3) ◽  
Author(s):  
Ika Ristia Rahman
Keyword(s):  
Antioxidant Activity ◽  
Free Radicals ◽  
Spectrophotometric Method ◽  
Test Results ◽  
Fruit Peel ◽  
Flavonoid Compounds ◽  
Activity Test ◽  
Maximum Protection ◽  
Sunscreen Formulation ◽  
Peel Extract

Background: UV lights are free radicals that can cause damage to the skin, such as redness, burning, pigmentation, and even cancer. Kenikir leaf purified extract (ETDK) and Tampoi fruit peel extract (EKBT) contain flavonoid compounds. Flavonoid compounds can be antioxidants and sunscreens due to the presence of chromophore groups that can absorb UV rays to reduce exposure to the skin. Objectives: This study aims to determine the antioxidant activity and the ability of sunscreen nano cream Purified extract of Kenikir leaves and Tampoi fruit peel extract. Material and metode:  Nanocream is made with 3 ETDTK-EKBT combination formulas, II ETDK formulas, III EKBT formulas. The antioxidant activity test was carried out using the DPPH (1,1-diphenyl-2-picrylhydrazyl) method and the sunscreen activity test using the UV-Vis spectrophotometric method to calculate the SPF value of the preparation (Mansur's method). Result: The results showed that the nano cream formula had a strong antioxidant activity with the per cent inhibition of formula I 78.28%, formula II 68.49%, and formula III 73.00%. The activity test results as a sunscreen formulation of purified extract nano cream from Kenikir leaves and nano cream from Tampoi fruit peel extract had extra protection ability with a sun-protecting factor value of 7 while the nano cream formula combined extract with an SPF value of 10 gave the maximum protection category. Conclusion: nano cream have potential as antioxidants and sunscreens.

The Utilization of Red Dragon Fruit Peel Extract (Hylocereus costaricencis) As A Natural Colorant of Dried Noodle

2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Silaturahmi Silaturahmi ◽  
Zaidiyah Zaidiyah ◽  
Tengku Mia Rahmiati
Keyword(s):  
Product Diversification ◽  
Fruit Peel ◽  
Physical Quality ◽  
Natural Colorant ◽  
Randomized Design ◽  
Solid Loss ◽  
Dragon Fruit ◽  
Completely Randomized Design ◽  
Peel Extract

The use of colorants in the dried noodle manufactures is an effort of product diversification. Besides of being used as a natural coloring agent, this peel extract is also used to improve nutritional value of the expected product. The purpose of this study was to determine the effect of red dragon fruit peel extract on the physical quality of dried noodle.  The study was conducted by using Completely Randomized Design (CRD) method with one factor, namely concentration of red dragon fruit peel extract (N1 = 10 ml, N2 = 15 ml, N3 = 20 ml, N4 = 25 ml, N5 = 30 ml).  The observations of its physical quality consisted of water absorption, solid loss during cooking, and organoleptic tests (aroma and color).  The best quality of dried noodle was obtained by using 30 ml red dragon fruit peel extract (N5) with physical properties, namely DSA levels of 351.92%, solid loss during cooking 4.78%, aroma 3.79 (like) and color 3.89 (like).

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