scholarly journals Formulasi Masker Gel Antioksidan Mengandung Ekstrak Kulit Buah Naga Merah (Hylocereus polyrhizus)

2017 ◽  
Vol 6 (1) ◽  
Author(s):  
Sunarmi Sunarmi ◽  
Susilo Yulianto
Keyword(s):  
Antioxidant Activity ◽  
Physical Stability ◽  
Fruit Peel ◽  
Dragon Fruit ◽  
Dpph Method ◽  
Before And After ◽  
The Face ◽  
Ic50 Values ◽  
High Antioxidant Activity ◽  
Dispersive Power

Abstract: Antioxidant, Red Dragon Fruit, Gel Mask. Skin is an organ that covers the entire human body, which has protection against external influences. Free radicals and the oxidation reaction can be inhibited by an antioxidant compound. Red dragon fruit peel is rarely used but has high antioxidant activity that can be used for skin care, especially facial skin. Red dragon fruit peel can be formulated into various dosage form of antioxidants for the face skin, one of which peel-off mask gel. This study aimed to test the antioxidant activity of peel-off mask gel with the active ingredient of red dragon fruit peel extracts. This research uses experimental methods. Red dragon fruit peel extracted by maceration in 70% ethanol and concentrated. Gel mask made in 3 variations extract concentration, ie formula A, B and C 0.175 g, 0.350 g and 0,700 g respectively. The physical stability test was conducted by cycling test for 6 cycles. The physical properties of the preparation were tested before and after storage include adhesion, dispersive power, pH, viscosity and time to dry. Antioxidant activity tested with DPPH method. Based on test results obtained physical stability, third-formula gel mask physically qualified and stable, except for the dispersive power. Antioxidant activity decreased after the storage. The highest activity was shown by formula C with an IC50 value of 3497.113 ppm. Based on IC50 values, this gel mask has an inactive. antioxidant activity.

scholarly journals Efisiensi Mikroenkapsulasi Ekstrak Kulit Buah Naga Super Merah (Hylocereus costaricensis) Tersalut Maltodekstrin Berdasarkan Kecepatan Pengadukan

KOVALEN ◽  
2020 ◽  
Vol 6 (1) ◽  
pp. 1-8
Author(s):  
Jaya Hardi ◽  
Dian Citra ◽  
Syamsuddin ◽  
Dwi Juli Pusptasari
Keyword(s):  
Antioxidant Activity ◽  
Particle Size ◽  
Free Radicals ◽  
Freeze Drying ◽  
Fruit Peel ◽  
Coating Efficiency ◽  
Dragon Fruit ◽  
Before And After ◽  
Ic50 Values ◽  
Peel Extract

Extract of super red dragon fruit peel has an antioxidant activity that can prevent free radicals from outside and its activity can be maintained by the coating of super red dragon fruit peel extract with maltodextrin The coating efficiency of super red dragon fruit peel extract with maltodextrin can be controlled with the speed of stirring during microencapsulation experiment. In order to obtain the highest microencapsulation efficiency and compare the antioxidant activity of super red dragon fruit peel extract before and after microencapsulation experiment. The study of coating efficiency has been done with microencapsulation that was carried out using the freeze-drying technique. During the microencapsulation of super red dragon fruit peel extract with freeze-drying technique, stirring speed in the microencapsulation process was 600 rpm, 800 rpm, 1000 rpm, 1200 rpm, and 1400 rpm respectively. From the microencapsulation process of super red dragon fruit peel extract coated with maltodextrin, it was obtained the highest microencapsulation efficiency at stirring speed of 800 rpm, which was 66.85% and had a particle size of 14.24 µm. It can be concluded that the antioxidant activity before and after encapsulation included a very weak category with IC50 values of 205.42 ppm for extracts and 246.32 ppm for microcapsules. Keywords: Super red dragon fruit peel, freeze-drying, microencapsulation, maltodextrin

scholarly journals Antioxidant and Anti-Hyaluronidase Activities of Dragon Fruit Peel Extract and Kaempferol-3-O-Rutinoside

2019 ◽  
Vol 30 (4) ◽  
pp. 247
Author(s):  
Liana Liana ◽  
Rizal Rizal ◽  
Wahyu Widowati ◽  
Fioni Fioni ◽  
Khainir Akbar ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Free Radicals ◽  
Human Life ◽  
Fruit Peel ◽  
Paired Samples ◽  
Dragon Fruit ◽  
Ic50 Value ◽  
Significant Difference ◽  
Ic50 Values ◽  
Peel Extract

Aging is a natural process in human life and is triggered by the presence of free radicals (ROS). The use of antioxidants from natural ingredients is one of the breakthroughs to overcome aging and counteract the harmful effects caused by the free radicals. This study aimed to determine and compare the antioxidant activity of H2O2 scavenging and hyaluronidase inhibition of red dragon fruit peel extract (DFPE) and kaempferol-3-o-rutinoside (KOR) compounds. Dragon fruit peel extract (DFPE) is obtained through extraction by maceration method using 70% ethanol solvent. The design of this study included antioxidant and anti-aging activity assay of EKBN and KOR at the series concentration of 15.63; 31.25; 62.50; 125; 250; 500 µg/mL through H2O2 scavenging, as well as the DFPE and KOR hyaluronidase inhibition assay at the series concentration of 5.21; 10.42; 20.83; 41.7; 83.33; 166.67 µg/mL. EKBN shows that the average activity of H2O2 scavenging is lower than KOR. In addition, the IC50 values of KOR for H2O2 scavenging is lower (351.46±2.30ug/mL) than DFPE (409.64±23.17ug/mL). While, KOR also has higher values of inhibitory activity than of the DFPE. However, the IC50 value of KOR for hyaluronidase inhibition activity was 84.07±10.46µg/mL, equivalent to the IC50 value of DFPE (85.32±10.24µg/mL). The presence of antioxidant and anti-aging activity in the EKBN is probably caused by betalain and the KOR compound itself contained in red dragon fruit. The results of the paired-samples T-test on antioxidant activity and anti-aging of DFPE and KOR showed non-significant difference. Thus, DFPE has an equivalent antioxidant and anti-aging through H2O2 scavenging and hyaluronidase activity as possessed by the KOR compound.

scholarly journals Daya Antioksidan Ekstrak Kulit Buah Naga Dan Sabun Ekstrak Kulit Buah Naga (Hylocereus Polyrhizuz)

2020 ◽  
Vol 6 (1) ◽  
pp. 22-25
Author(s):  
Mohamad Ikram ◽  
Nining Sugihartini ◽  
Any Guntarti
Keyword(s):  
Antioxidant Activity ◽  
Test Results ◽  
Fruit Peel ◽  
Fruit Extract ◽  
Dragon Fruit ◽  
Dpph Method ◽  
Coloring Agents ◽  
Peel Extract

Red dragon fruit peel extract contains betalain which has antioxidant activity. In addition, this extract also contains dyes that can be used as coloring agents in cosmetic preparations. The purpose of this study was to study the activity of dragon fruit peel extract and red dragon fruit peel extract soap with various concentrations. Antioxidant activity is taken by the DPPH method. The concentration of red dragon fruit peel extract in soap is 0.3; 0.6; 0.9%. Test results show red dragon fruit extract soap has lower antioxidant activity than the extract. The increased concentration of the extract caused an increase in the antioxidant activity of the red dragon fruit peel extract soap.

scholarly journals Yield, chemical composition and functional properties of essential oils from Mentha spicata (Lamiaceae) in Santiago del Estero, Argentina

2019 ◽  
Vol 11 (3) ◽  
pp. 327-333
Author(s):  
Diego Ariel Meloni ◽  
Julia Andrea Lescano ◽  
Maria Paz Arraiza ◽  
Rosa Elizabeth Beltrán
Keyword(s):  
Antioxidant Activity ◽  
Chemical Composition ◽  
Essential Oil ◽  
Pharmaceutical Products ◽  
Acetylcholinesterase Inhibition ◽  
Mentha Spicata ◽  
Essential Components ◽  
Dpph Method ◽  
Ic50 Values ◽  
High Antioxidant Activity

Introduction: Mentha spicata, commonly known as spearmint, is the most common and popular cultivated mint, and is used in food, perfumes and pharmaceutical products. Objective: To determine the yield, composition and properties of essential oil from M. spicata grown in Santiago del Estero, Argentina. Methods: We used steam distillation, gas chromatography and mass spectrometry to determine chemical composition, antioxidant activity and acetylcholinesterase inhibition. Results: Essential oil yield ranged from 0.8 to 1.3 mL·100 g-1 DM. The main essential components were carvone (60,72-68,09%), limonene (14,23-16,41%), α-pinene (0,12-3,14%), β-myrcene (0,35-2,33%), 1,8-cineole (1,69-2,73%), cis-dihydrocarvone (1,82-2,31%), trans-craveol (1,09-1,19%), β-bourbonene (2,44-3,17%) and β-Caryophyllene (1,42-1,82%). The oil had high antioxidant activity, with IC50 values among 7,5-12,06 µg/mL (DPPH method) and 26,94-38,14 µg/mL (β-carotene/linoleic acid method). It had good inhibition of acetylcholisterenase, with enzyme inhibition zones of 0,4-0,9 cm. Conclusion: The yield, quality and properties of the essential oil from M. spicata grown in Santiago del Estero meet market requirements.

scholarly journals Uji Aktivitas Antioksidan Body Butter Ekstrak Etanol Kulit Buah Naga Merah dengan Metode DPPH

2021 ◽  
Vol 6 (2) ◽  
pp. 178-184
Author(s):  
Repining Tiyas Sawiji ◽  
Elisabeth Oriana Jawa La
Keyword(s):  
Antioxidant Activity ◽  
Cell Damage ◽  
Pharmaceutical Preparation ◽  
Ethanol Extract ◽  
The Body ◽  
Fruit Peel ◽  
Activity Test ◽  
Dragon Fruit ◽  
Ic50 Values ◽  
Hylocereus Polyrhizus

Red dragon fruit peels (Hylocereus polyrhizus) are considered important by the community. While the red dragon fruit peel contains flavonoids, betacyanin, anthocyanin, and vitamin C which have antioxidant activity so that it can ward off free radiation and prevent cell damage. Antioxidants are molecules that can prevent the oxidation of other molecules. Antioxidants can protect the skin from various free radical cell damage. The body butter is a pharmaceutical preparation in the cosmetic field that can be used for skin health care. This study aims to determine the percentage of antioxidant activity and IC50 values in the body butter ethanol extract of red dragon fruit peels. Red dragon fruit peels were extracted first using the maceration method with 96% ethanol solvent. The antioxidant activity test was measured using UV-Vis spectrophotometry. The results showed that the antioxidant activity value of formula I obtained IC50 values (56.17 μg / mL), formula II IC50 values (88.26 μg / mL), and formula III IC50 values (146.05 μg / mL). From the results obtained, the body butter formula which has the greatest activity is the formula I (AAI = 0.7). Antioxidant activity in body butter preparations is included in the group of moderate antioxidants.

Photostability Study on Character and Antioxidant Activity of Tomato Extract (Solanum lycopersicum l.) in Nanostructured Lipid Carrier (NLC) and Conventional Creame

2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Noorma Rosita ◽  
Dewi Haryadi ◽  
Tristiana Erawati ◽  
Rossa Nanda ◽  
Widji Soeratri
Keyword(s):  
Antioxidant Activity ◽  
Physical Stability ◽  
Nanostructured Lipid Carrier ◽  
Uvb Radiation ◽  
K Value ◽  
Antioxidant Power ◽  
Solanum Lycopersicum L ◽  
Tomato Extract ◽  
Dpph Method ◽  
High Shear Homogenization

The aim of this study was to investigate the ability of NLC in increasing photostability of tomato extract in term of antioxidant activity. Photostability testing on antioxidant activity of samples were conducted by accelerating method using UVB radiation 32.400 joule for 21 hours radiation. Antioxidant activity was measured by DPPH method. NLC was made by High Shear Homogenization (HPH) method at 24000 rpm for 4 cycles, while conventional creame was made by low speed at 400 rpm. The product were characterized include: pH, viscosity, and particle size. There were had difference characters and physical stability. NLC had smaller size, more homogenous and more stable than conventional creame. It was known that stability of antioxidant activity of tomato extract in NLC system higher than in conventional creame. That was showed with k value, as constanta of rate scavenging activity decreasing in antioxidant power between time (Sigma 2-tail less than 0.005) of NLC and conventional creame were: 2.03x10-2 %/hour ±0.08 (3.94) and 4.71x 10-2 %/ hour ±0.23 (4.88) respectively.

scholarly journals ANTIOXIDANT ACTIVITY OF RED DRAGON FRUIT PEEL (HYLOCEREUS POLYRHIZUS (F.A.C. WEBER) BRITTON AND ROSE) ISOLATES USING 2,2-DIPHENYL-1-PICRYLHYDRAZYL METHOD

2018 ◽  
Vol 11 (1) ◽  
pp. 124 ◽  
Author(s):  
Sri Wahdaningsih ◽  
Subagus Wahyuono ◽  
Sugeng Riyanto ◽  
Retno Murwanti
Keyword(s):  
Antioxidant Activity ◽  
Liquid Chromatography ◽  
Medicinal Plants ◽  
Thin Layer ◽  
Preparative Thin Layer Chromatography ◽  
Fruit Peel ◽  
Dragon Fruit ◽  
Vacuum Liquid Chromatography ◽  
Layer Chromatography ◽  
Hylocereus Polyrhizus

  Objective: Indonesia is a country which has various natural resources including medicinal plants. Among the plants, red dragon fruit is interesting to be studied. In this study, antioxidant activity of red dragon fruit peel (Hylocereus polyrhizus (F.A.C. Weber) Britton and Rose) isolate was tested using 2,2-diphenyl-1-picrylhydrazyl method.Methods: Isolation of active compounds was performed through the application of vacuum liquid chromatography and preparative thin-layer chromatography (TLC). Antioxidant activity was tested using both TLC and spectrophotometry.Result: Results revealed that the values of IC50 of isolate 1 and 2 were 2.952, 14 μg/mL and 25.635,95 μg/mL, respectively.Conclusion: Isolate of dragon fruit has antioxidant activity. The compound which results in antioxidant activity is terpenoid and steroid.

scholarly journals Aktivitas Antioksidan Ekstrak Etanol Buah, Daun, Batang Dan Rimpang Pada Tanaman Wualae (Etlingera Elatior (Jack) R.M Smith)

2019 ◽  
Vol 5 (2) ◽  
pp. 189-197 ◽  
Author(s):  
Asriullah Jabbar ◽  
Wahyuni Wahyuni ◽  
Muh Hajrul Malaka ◽  
Apriliani Apriliani
Keyword(s):  
Antioxidant Activity ◽  
Vitamin C ◽  
Typhoid Fever ◽  
Skin Diseases ◽  
Activity Test ◽  
Ic50 Value ◽  
Dpph Method ◽  
Ic50 Values ◽  
Ethanol Extracts ◽  
Etlingera Elatior

Wualae (Etlingera elatior (Jack) R.M Smith) is one of the plants in the Zingiberaceae family, widely used in medicine ranging from rhizomes, fruits, and flowers. Empirically Wualae are usually used by people for treating skin diseases, flavoring food, a natural soap, and in Southeast Sulawesi, it is used to treat typhoid fever. This study aims to examine the antioxidant activity of Wualae (Etlingera elatior) plant. The plant extracts were extracted by maceration method, antioxidant activity test was performed by 2,2-Diphenyl-1-picrylhydrazyl (DPPH) method. The results showed that ethanol extracts of fruits, leaves, stems and rhizomes of Wualae (Etlingera elatior) has the potential antioxidant activity with the IC50 values of 72.518 mg/L, 99.890 mg/L, 52.345 mg/L and 58.638 mg/L, respectively. and Vitamin C has IC50 value of 3,787 mg/L.

scholarly journals UJI AKTIVITAS ANTIOKSIDAN SPONS Stylissa sp. DENGAN MENGGUNAKAN METODE DPPH (1,1-difenil-2-pikrilhidrazil)

PHARMACON ◽  
2020 ◽  
Vol 9 (3) ◽  
pp. 419
Author(s):  
Samuel I.M. Sibarani ◽  
Adithya Yudistira ◽  
Deby A. Mpila
Keyword(s):  
Antioxidant Activity ◽  
Cell Wall ◽  
Free Radicals ◽  
Ethanol Extract ◽  
Dna Bases ◽  
Oxidation Reactions ◽  
Terrestrial Plants ◽  
Dpph Method ◽  
High Antioxidant Activity ◽  
Ethanol Extracts

ABSTRACTHabitat of sponge Stylissa sp., were under the sea and these sponges contain active compounds, which are more active than the compounds produced by terrestrial plants. Antioxidants are inhibitors of oxidation reactions due to the free radicals, which can cause weak damage to unsaturated cells, cell wall membranes, blood vessels, DNA bases, and lipid tissue, that causing disease. The study was conducted to determine the antioxidant activity of ethanol extracts  of sponge Stylissa sp., which is located on the Bangka Island, Likupang District, North Minahasa Regency. Sponge Stylissa sp., was extracted by maceration with using ethanol. Testing of antioxidant activity was carried out by the DPPH method measured by a UV-Vis spectrophotometer. The results of the study showed that ethanol extracts of sponge Stylissa sp., has antioxidant activity in each concentration and the highest at a concentration of 100 mg / L. The conclusion is a ethanol extract of sponge Stylissa sp. have high antioxidant activity with a concentration of 25 mg/L (77,40%), concentration of 50 mg/L (85,63%), concentration of 75 mg/L (88,66%), and concentration 100 mg/L (88,96%). Key words: Stylissa sp. Sponge, Antioxidant, DPPH (1,1-diphenyl-2-picrylhydrazyl) ABSTRAKHabitat dari spons Stylissa sp. terdapat di bawah laut dan spons ini mengandung senyawa aktif yang persentase keaktifannya lebih besar dibandingkan dengan senyawa-senyawa yang dihasilkan oleh tumbuhan darat. Antioksidan adalah zat penghambat reaksi oksidasi akibat radikal bebas yang dapat menyebabkan kerusakan lemah tak jenuh, membran dinding sel, pembuluh darah, basa DNA, dan jaringan lipid sehingga menimbulkan penyakit. Penelitian dilakukan untuk mengetahui aktivitas antioksidan ekstrak etanol biota laut spons Stylissa sp. yang terdapat di pulau Bangka, Kecamatan Likupang, Kabupaten Minahasa Utara. Spons Stylissa sp. ini diekstrak dengan metode maserasi menggunakan etanol. Pengujian aktivitas antioksidan ini dilakukan dengan metode DPPH yang diukur dengan alat spektrofotometer UV-Vis. Hasil dari penelitian menunjukan bahwa ekstrak etanol spons Stylissa sp. memiliki aktivitas antioksidan disetiap konsentrasi dan yang tertinggi pada konsentrasi 100 mg/L. Kesimpulan yang didapat bahwa ekstrak etanol spons Stylissa sp. memiliki aktivitas antioksidan yang tinggi dengan konsentrasi 25 mg/L (77,40%), konsentrasi 50 mg/L (85,63%), konsentrasi 75 mg/L (88,66%), dan konsentrasi 100 mg/L (88,96%). Kata Kunci : Spons Stylissa sp., Antioksidan, DPPH (1,1-difenil-2-pikrilhidrazil)

scholarly journals UJI AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL BULBUS BAWANG DAYAK (Eleutherine americana Merr) DENGAN METODE DPPH (1,1-Diphenyl-2-Picrylhydrazyl)

PHARMACON ◽  
2020 ◽  
Vol 9 (3) ◽  
pp. 451
Author(s):  
Rizkah V. Mokoginta ◽  
Herny E. I. Simbala ◽  
Karlah L.R Mansauda
Keyword(s):  
Antioxidant Activity ◽  
Vitamin C ◽  
Ethanol Extract ◽  
Antioxidant Compounds ◽  
Onion Plant ◽  
Dpph Method ◽  
Ic50 Values ◽  
Experimental Laboratory ◽  
Ethanol Extracts ◽  
Eleutherine Americana

ABSTRACTDayak onion plant (Eleutherine americana Merr.) or commonly called forest onion is a typical plant of Central Kalimantan that has been used by local peoples for cure a various types of diseases. This study aims to determine the activity of antioxidant compounds from Dayak bulb ethanol extracts from Kotamobagu City. This research method is an experimental laboratory. Initially the Dayak bulb sample was extracted maceration with 96% ethanol solvent then evaporated until a thick extract was obtained. As a parameter, the DPPH method (1,1-diphenyl-2-picrylhydrazyl) was used to test the antioxidant activity of the samples at concentrations of 50, 60, 70, 80 and 90 mg / L and as a comparison standard used Vitamin C with concentrations of 2, 4, 6, 8 and 10 mg / L. The results obtained showed antioxidant activity in Dayak bulb ethanol extracts with IC50 values of 41.46 mg / L and on vitamin C IC50 values of 1.04 mg / L. Based on these results it can be concluded that the onion bulb ethanol extract has very strong antioxidant activity. Keywords: Dayak Onion bulbs, Activity, Antioxidant, DPPH  ABSTRAK Tanaman bawang Dayak (Eleutherine americana Merr.) atau biasa disebut bawang hutan merupakan tanaman khas Kalimantan Tengah yang sudah dipergunakan masyarakat lokal sebagai obat berbagai jenis penyakit. Penelitian ini bertujuan untuk mengetahui aktivitas senyawa antioksidan dari ekstrak etanol bulbus bawang Dayak yang berasal dari Kota Kotamobagu. Metode penelitian ini adalah eksperimental laboratorium. Awalnya sampel bulbus bawang Dayak diekstraksi maserasi dengan pelarut etanol 96% kemudian dievaporasi hingga didapatkan ekstrak kental. Sebagai parameter, digunakan metode DPPH (1,1-diphenyl-2-picrylhydrazyl) untuk pengujian aktivitas antioksidan sampel pada konsentrasi 50, 60, 70, 80 dan 90 mg/L dan sebagai standar pembanding digunakan Vitamin C dengan konsentrasi 2, 4, 6, 8 dan 10 mg/L. Hasil penelitian yang didapat menunjukkan aktivitas antioksidan pada ekstrak etanol bulbus bawang Dayak dengan nilai IC50 sebesar 41,46 mg/L dan pada vitamin C nilai IC50 sebesar 1,04 mg/L. Berdasarkan hasil tersebut dapat disimpulkan bahwa ekstrak etanol bulbus bawang Dayak memiliki aktivitas antioksidan yang sangat kuat. Kata kunci: Bulbus Bawang Dayak, Aktivitas, Antioksidan, DPPH

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