scholarly journals A dry gangrene signing SARS-CoV2 infection in a vulnerable patient

2021 ◽  
Author(s):  
Dorsaf Elinkichari ◽  
Faten Rabhi ◽  
Yosra Ben Ariba ◽  
Kahena Jaber ◽  
Raouf Dhaoui
Keyword(s):  
The Novel ◽  
Main Target ◽  
Vulnerable Patient ◽  
Novel Virus

Although lungs represent the main target of the SARS-CoV2, the novel virus may affect other tissues. In the pandemic context, unexplained cutaneous ischemic lesions would be suggestive of the infection and should draw attention to a serious course of the disease.

scholarly journals Sex Differences in Spatial Activity and Anxiety Levels in the COVID-19 Pandemic from Evolutionary Perspective

2021 ◽  
Vol 13 (3) ◽  
pp. 1110
Author(s):  
Olga Semenova ◽  
Julia Apalkova ◽  
Marina Butovskaya
Keyword(s):  
Environmental Risks ◽  
Economic Losses ◽  
General Level ◽  
The Novel ◽  
Health Attitudes ◽  
Spatial Activity ◽  
Sexual Specialization ◽  
The Face ◽  
Novel Virus ◽  
Virus Spreading

Despite the enforced lockdown regime in late March 2020 in Russia, the phenomenon of the continued virus spreading highlighted the importance of studies investigating the range of biosocial attributes and spectrum of individual motivations underlying the permanent presence of the substantial level of spatial activity. For this matter, we conducted a set of surveys between March and June 2020 (N = 492). We found that an individual’s health attitude is the most consistent factor explaining mobility differences. However, our data suggested that wariness largely determines adequate health attitudes; hence, a higher level of wariness indirectly reduced individual mobility. Comparative analysis revealed the critical biosocial differences between the two sexes, potentially rooted in the human evolutionary past. Females were predisposed to express more wariness in the face of new environmental risks; therefore, they minimize their mobility and outdoor contacts. In contrast to them, the general level of spatial activity reported by males was significantly higher. Wariness in the males’ sample was less associated with the novel virus threat, but to a great extent, it was predicted by the potential economic losses variable. These findings correspond to the evolutionary predictions of sexual specialization and the division of family roles.

scholarly journals COVID 19 Dawn from Wuhan: “The Number Game”

2020 ◽  
Vol 32 (3) ◽  
pp. 564-568
Author(s):  
Sumit Chawla ◽  
Harinder Singh ◽  
Bharti Chawla
Keyword(s):  
Case Fatality ◽  
Epidemiological Data ◽  
Unknown Etiology ◽  
The Novel ◽  
Time Data ◽  
Public Health Response ◽  
Expected Time ◽  
Hospitalization Rates ◽  
Health Response ◽  
Novel Virus

On 31st December 2019, China informed local WHO office of "cases of pneumonia of unknown etiology detected in Wuhan. As of 6th May 2020, there are nearly 3.6 million cases of corona virus infection and approximately 0.25 million deaths worldwide. The real-time data regarding the actual number of cases, as it originates from the epicenter is the key to the estimation of the case fatality rate, hospitalization rates, expected timeline of arrival of contagion, and other epidemiological data. The novel virus has no available literature pertaining to its epidemiological parameters, on which experts can base their estimates and hence the challenge in planning for epidemic management. Bolstering this challenge are the reports alleging under-reporting by Chinese authorities. Alleged toned down numbers could have led to erroneously low estimates contributing to inadequate public health response globally. We conducted a simulation on epidemiological model of COVID-19 to find out expected time off arrival of infections and mortality in different countries and compared this to actual data.

scholarly journals Psychological support in times of COVID-19: the Essen community-based CoPE concept

2020 ◽  
Vol 42 (3) ◽  
pp. 649-650 ◽  
Author(s):  
Alexander Bäuerle ◽  
Eva-Maria Skoda ◽  
Nora Dörrie ◽  
Juliane Böttcher ◽  
Martin Teufel
Keyword(s):  
Mental Health ◽  
Treatment Options ◽  
Metropolitan Region ◽  
Federal State ◽  
The Novel ◽  
Individual Freedom ◽  
Community Based ◽  
Psychological Burden ◽  
Ruhr Area ◽  
Novel Virus

Abstract The SARS CoV-2-virus (COVID-19) pandemic is pushing national and international structures to their limits. Little is known about treatment options to combat the novel virus, but the same applies to the effects of COVID-19 on people’s mental health. In Germany, as in many other countries, governmental actions impact peoples’ individual freedom. These highly necessary actions to slow down the spread of the virus, however, are a burden to the community. We established a structured concept to support psychological burdened people in Essen, which is located in the Ruhr area, a metropolitan region with more than 5.1 million inhabitants in the heart of the federal state North Rhine Westphalia. The psychological burden following the spread of the virus and individual restrictions should not be neglected.

scholarly journals A Novel RNA Virus, Macrobrachium rosenbergii Golda Virus (MrGV), Linked to Mass Mortalities of the Larval Giant Freshwater Prawn in Bangladesh

Viruses ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 1120
Author(s):  
Chantelle Hooper ◽  
Partho P. Debnath ◽  
Sukumar Biswas ◽  
Ronny van Aerle ◽  
Kelly S. Bateman ◽  
...  
Keyword(s):  
Virus Assembly ◽  
Rna Virus ◽  
Macrobrachium Rosenbergii ◽  
Freshwater Prawn ◽  
The Novel ◽  
Protein Motifs ◽  
Giant Freshwater Prawn ◽  
Yellow Head Virus ◽  
Novel Virus ◽  
Mass Mortalities

Mass mortalities of the larval stage of the giant freshwater prawn, Macrobrachium rosenbergii, have been occurring in Bangladesh since 2011. Mortalities can reach 100% and have resulted in an 80% decline in the number of hatcheries actively producing M. rosenbergii. To investigate a causative agent for the mortalities, a disease challenge was carried out using infected material from a hatchery experiencing mortalities. Moribund larvae from the challenge were prepared for metatranscriptomic sequencing. De novo virus assembly revealed a 29 kb single-stranded positive-sense RNA virus with similarities in key protein motif sequences to yellow head virus (YHV), an RNA virus that causes mass mortalities in marine shrimp aquaculture, and other viruses in the Nidovirales order. Primers were designed against the novel virus and used to screen cDNA from larvae sampled from hatcheries in the South of Bangladesh from two consecutive years. Larvae from all hatcheries screened from both years were positive by PCR for the novel virus, including larvae from a hatchery that at the point of sampling appeared healthy, but later experienced mortalities. These screens suggest that the virus is widespread in M. rosenbergii hatchery culture in southern Bangladesh, and that early detection of the virus can be achieved by PCR. The hypothesised protein motifs of Macrobrachium rosenbergii golda virus (MrGV) suggest that it is likely to be a new species within the Nidovirales order. Biosecurity measures should be taken in order to mitigate global spread through the movement of post-larvae within and between countries, which has previously been linked to other virus outbreaks in crustacean aquaculture.

scholarly journals COVID-19 and the Heart

2020 ◽  
pp. 1-5 ◽  
Author(s):  
Chaitanya Rojulpote ◽  
Karthik Gonuguntla ◽  
Shivaraj Patil ◽  
Abhijit Bhattaru ◽  
Paco Bravo
Keyword(s):  
Cardiovascular System ◽  
The Novel ◽  
Health Crisis ◽  
Risk Of Death ◽  
Increased Risk ◽  
The World ◽  
Significant Burden ◽  
Coronary Syndromes ◽  
Novel Virus ◽  
Underlying Mechanisms

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which causes coronavirus disease 2019 (COVID-19) has resulted in a global health crisis. Prior to the arrival of this viral pandemic, the world was already plagued with a significant burden of cardiovascular disease. With the introduction of the novel virus, the world now faces a double jeapordy. Early reports have suggested an increased risk of death in individuals with underlying cardio-metabolic disorders. The exact effects of COVID-19 on the cardiovascular system are not well determined, however lessons from prior viral epidemics suggest that such infections can trigger acute coronary syndromes, arrhythmias and heart failure via direct and indirect mechanisms. In this article, we aimed to discuss the effects and potential underlying mechanisms of COVID -19 as well as potential implications of treatments targeted against this virus on the cardiovascular system.

scholarly journals COVID-19: a novel zoonotic disease caused by a coronavirus from China: what we know and what we don't

2020 ◽  
Vol 41 (1) ◽  
pp. 45 ◽  
Author(s):  
John S Mackenzie ◽  
David W Smith
Keyword(s):  
Public Health Emergency ◽  
World Health ◽  
Director General ◽  
The Novel ◽  
New Disease ◽  
Unknown Aetiology ◽  
The Third ◽  
The World ◽  
Novel Virus ◽  
Health Organization

At the end of December, 2019, a new disease of unknown aetiology appeared in Wuhan, China. It was quickly identified as a novel betacoronavirus, and related to SARS-CoV and a number of other bat-borne SARS-like coronaviruses. The virus rapidly spread to all provinces in China, as well as a number of countries overseas, and was declared a Public Health Emergency of International Concern by the Director-General of the World Health Organization on 30 January 2020. This paper describes the evolution of the outbreak, and the known properties of the novel virus, SARS-CoV-2 and the clinical disease it causes, COVID-19, and comments on some of the important gaps in our knowledge of the virus and the disease it causes. The virus is the third zoonotic coronavirus, after SARS-CoV and MERS-CoV, but appears to be the only one with pandemic potential.

COVID-19 Illness: Mother–Baby Separation, Viruses, and Breastfeeding

2020 ◽  
pp. CLINLACT-D-20-00008
Author(s):  
Dena Duran ◽  
Jarold T. Johnston
Keyword(s):  
Case Reports ◽  
Economic Cost ◽  
Population Based ◽  
Early Summer ◽  
Direct Care ◽  
The Novel ◽  
Single Family ◽  
Alternative Approach ◽  
Novel Virus ◽  
Novel Coronavirus

ObjectivesSome hospitals have instituted separation of mothers and their newborn(s) when SARS-CoV-2 is suspected or confirmed in the mother. Limited data are available for SARS-CoV-2 vertical transmission, including studies on breast milk. This article looks at SARS CoV-2 case studies and data to date as well as prior pertinent research.MethodsInformal searches of PUBMED, CINAHL and Ovid Emcare were used to identify early reports of vertical transmissions of the novel Coronavirus, case reports, and population based reports of early evolving protocols and their outcomes. As this is a novel virus the authors used previously identified anti-infectivity and antiviral mechanisms of human milk on other similar viruses to guide analysis. Further this article reviewed the well established literature regarding the risks of undue infant separation which negatively affect nearly every aspect of infant and maternal health.ResultsInformal searches conducted in the spring and early summer of 2020 identified 14 early reports attempting to analyze the initial and evolving global response to SARS-CoV-2 and the effects of the virus on the maternal-infant dyad.ConclusionThe feasibility of single-family rooms and support for breastfeeding as an alternative approach that addresses many of the risks favorably and reduces economic cost, both in lifetime disease burden and direct care are discussed. Initial reports seem to indicate that immediate separation of the mother from her newborn is likely to increase the risk to both mother and infant.

scholarly journals A New Flavivirus and a New Vector: Characterization of a Novel Flavivirus Isolated from Uranotaenia Mosquitoes from a Tropical Rain Forest

2009 ◽  
Vol 83 (9) ◽  
pp. 4462-4468 ◽  
Author(s):  
Sandra Junglen ◽  
Anne Kopp ◽  
Andreas Kurth ◽  
Georg Pauli ◽  
Heinz Ellerbrok ◽  
...  
Keyword(s):  
Rain Forest ◽  
Phylogenetic Analyses ◽  
Cell Culture Supernatant ◽  
The Novel ◽  
Glycosylation Sites ◽  
Ns3 Protein ◽  
Distinct Cluster ◽  
Infected Cells ◽  
Novel Virus

ABSTRACT A novel flavivirus was isolated from Uranotaenia mashonaensis, a mosquito genus not previously known to harbor flaviviruses. Mosquitoes were caught in the primary rain forest of the Taï National Park, Côte d'Ivoire. The novel virus, termed nounané virus (NOUV), seemed to grow only on C6/36 insect cells and not on vertebrate cells. Typical enveloped flavivirus-like particles of 60 to 65 nm in diameter were detected by electron microscopy in the cell culture supernatant of infected cells. The full genome was sequenced, and potential cleavage and glycosylation sites and cysteine residues were identified, suggesting that the processing of the NOUV polyprotein is similar to that of other flaviviruses. Phylogenetic analyses of the whole polyprotein and the NS3 protein showed that the virus forms a distinct cluster within the clade of mosquito-borne flaviviruses. Only a distant relationship to other known flaviviruses was found, indicating that NOUV is a novel lineage within the Flaviviridae.

scholarly journals Infants and toddlers oral health care during COVID-19 - A review

2021 ◽  
Vol 6 (1) ◽  
pp. 14-15
Author(s):  
Diksha Sharma ◽  
◽  
Sanjay Chachra ◽  
Shivani Targotra ◽  
Sonika Peer ◽  
...  
Keyword(s):  
Health Care ◽  
Oral Health ◽  
Oral Care ◽  
Oral Health Care ◽  
The Novel ◽  
Infants And Toddlers ◽  
Good Care ◽  
Novel Virus

Staying up healthy during this corona pandemic is very important along with that of the proper oral health care. Following up with a regular oral care routine plays an important role. It is bit difficult to seek treatment for the children during the novel virus. So, it is better to avoid any unnecessary visits to a dentist just by taking good care of the child’s oral health.

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