scholarly journals Levels and risk assessment of selected persistent organic compounds in dust samples from Tianjin, China

2019 ◽  
pp. 295-303
Author(s):  
Biljana Skrbic ◽  
Igor Antic ◽  
Ji Yaqin
Keyword(s):  
Gas Chromatography ◽  
Hazard Quotient ◽  
Principal Component ◽  
Street Dust ◽  
Carcinogenic Risk ◽  
Summer Season ◽  
Limit Of Quantification ◽  
Persistent Organic Compounds ◽  
Total Concentrations ◽  
Indicator Pcbs

The aim of this paper was to determine spatial variation of 6 indicator polychlorinated biphenyls (PCBs) and 18 organochlorine pesticides (OCPs) in street dust samples (n=49) collected during summer season from suburban/urban zones of Tianjin, China. Sample preparation was performed by using accelerated solvent extraction with simultaneous extraction and clean-up of PCBs and OCPs, while quantification was carried out using gas chromatography coupled with microelectro absorption detector and gas chromatography coupled with mass spectrometry. The total concentrations of studied PCBs varied from <method limit of quantification (MLOQ) (0.028) to 6.38 ng/g (mean 0.72 ng/g and the median value of 0.028 ng/g), while the total concentrations of studied OCPs varied from <MLOQ (0.020) to 123 ng/g (mean 33.6 ng/g and the median value of 25.9 ng/g). Regarding the OCPs analyzed, dichlorodiphenyltrichloroethanes (DDTs), beta-hexachlorocyclohexane (?-HCH), and ?-HCH were quantified, while all indicator PCBs were quantified at least in one sample, with the exception of PCB 180. Additional, principal component analysis was performed to evaluate relationships between quantified compounds (PCBs, DDTs, and HCHs) and dust characteristics. No correlation was found among quantified compounds and dust characteristics with the exception of PCB 101 and PCB 138, which correlates positively with pH and negatively with conductivity. The total lifetime carcinogenic risk (TLCR) as well as total non-carcinogenic risk hazard quotient (TnHQ) indicated that the risk to the human population related to the presence of OCPs and PCBs in dust samples was acceptable.

scholarly journals Real Time Breath Analysis Using Portable Gas Chromatography for Adult Asthma Phenotypes

Metabolites ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. 265
Author(s):  
Ruchi Sharma ◽  
Wenzhe Zang ◽  
Menglian Zhou ◽  
Nicole Schafer ◽  
Lesa A. Begley ◽  
...  
Keyword(s):  
Gas Chromatography ◽  
Real Time ◽  
Rapid Assessment ◽  
Principal Component ◽  
Corticosteroid Treatment ◽  
Breath Analysis ◽  
Blood Eosinophil ◽  
Exhaled Breath ◽  
Respiratory Illnesses ◽  
Linear Discriminant

Asthma is heterogeneous but accessible biomarkers to distinguish relevant phenotypes remain lacking, particularly in non-Type 2 (T2)-high asthma. Moreover, common clinical characteristics in both T2-high and T2-low asthma (e.g., atopy, obesity, inhaled steroid use) may confound interpretation of putative biomarkers and of underlying biology. This study aimed to identify volatile organic compounds (VOCs) in exhaled breath that distinguish not only asthmatic and non-asthmatic subjects, but also atopic non-asthmatic controls and also by variables that reflect clinical differences among asthmatic adults. A total of 73 participants (30 asthma, eight atopic non-asthma, and 35 non-asthma/non-atopic subjects) were recruited for this pilot study. A total of 79 breath samples were analyzed in real-time using an automated portable gas chromatography (GC) device developed in-house. GC-mass spectrometry was also used to identify the VOCs in breath. Machine learning, linear discriminant analysis, and principal component analysis were used to identify the biomarkers. Our results show that the portable GC was able to complete breath analysis in 30 min. A set of nine biomarkers distinguished asthma and non-asthma/non-atopic subjects, while sets of two and of four biomarkers, respectively, further distinguished asthmatic from atopic controls, and between atopic and non-atopic controls. Additional unique biomarkers were identified that discriminate subjects by blood eosinophil levels, obese status, inhaled corticosteroid treatment, and also acute upper respiratory illnesses within asthmatic groups. Our work demonstrates that breath VOC profiling can be a clinically accessible tool for asthma diagnosis and phenotyping. A portable GC system is a viable option for rapid assessment in asthma.

scholarly journals Influences of Smoking in Traditional and Industrial Conditions on Flavour Profile of Harbin Red Sausages by Comprehensive Two-Dimensional Gas Chromatography Mass Spectrometry

Foods ◽  
2021 ◽  
Vol 10 (6) ◽  
pp. 1180
Author(s):  
Xiaoyu Yin ◽  
Qian Chen ◽  
Qian Liu ◽  
Yan Wang ◽  
Baohua Kong
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Volatile Compounds ◽  
Solid Phase ◽  
Meat Products ◽  
Principal Component ◽  
Quality Characteristics ◽  
Gas Chromatography Mass Spectrometry ◽  
Two Dimensional ◽  
Chromatography Mass Spectrometry

Smoking is mainly used to impart desirable flavour, colour and texture to the products. Various food smoking methods can be divided into traditional and industrial methods. The influences of three different smoking methods, including traditional smouldering smoke (TSS), industrial smouldering smoke (ISS) and industrial liquid smoke (ILS), on quality characteristics, sensory attributes and flavour profiles of Harbin red sausages were studied. The smoking methods had significant effects on the moisture content (55.74–61.72 g/100 g), L*-value (53.85–57.61), a*-value (11.97–13.15), b*-value (12.19–12.92), hardness (24.25–29.17 N) and chewiness (13.42–17.32). A total of 86 volatile compounds were identified by headspace solid phase microextraction combined with comprehensive two-dimensional gas chromatography mass spectrometry (GC × GC-qMS). Among them, phenolic compounds were the most abundant compounds in the all sausages. Compared with sausages smoked with smouldering smoke, the ILS sausages showed the highest content of volatile compounds, especially phenols, alcohols, aldehydes and ketones. Principal component analysis showed that the sausages smoked with different methods had a good separation based on the quality characteristics and GC × GC-qMS data. These results will facilitate optimising the smoking methods in the industrial production of smoked meat products.

scholarly journals Human health impact assessment and temporal distribution of trace elements in Copșa Mică- Romania

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Katalin Bodor ◽  
Zsolt Bodor ◽  
Alexandru Szép ◽  
Róbert Szép
Keyword(s):  
Trace Elements ◽  
Hazard Quotient ◽  
Temporal Distribution ◽  
Health Impact ◽  
Temporal Variations ◽  
Carcinogenic Risk ◽  
Dermal Absorption ◽  
Safe Limit ◽  
Adults And Children ◽  
Mean Concentration

AbstractThe present study aims to analyze the temporal variations of PM10 and to assess the health risk indexes caused by trace elements from particulate matter (PM10) via inhalation, ingestion, and dermal absorption by adults and children in Copșa Mică (Romania) during 2009–2019. The results revealed a high multi-annual mean concentration of PM10 and trace elements. The analyzed air pollutants showed a decreasing trend during the studied years, therefore 44.11%, 43.48%, 36.07%, 16.02%, and 15.80% lower values were observed for As, Cd, Ni, PM10, and Pb, respectively, due to environmental regulations. The daily exceedance percentage of Pb and Cd was very high, representing 21.74% and 11.26%, followed by PM10 and As concentrations with 4.72% and 3.92%. The ratio between the trace element concentration measured in Copșa Mică and the country average was 2.46, 4.01, 2.44 and 10.52 times higher for As, Cd, Ni and Pb. The calculated Hazard Quotient values via inhalation were higher than the safe limit (1), which accounted 1.81, 3.89 and 4.52, for As, Cd and Ni, respectively, indicating that the trace elements might present a non-carcinogenic risk to both adults and children. Furthermore, the concentration of all studied trace elements in Copșa Mică showed cancer risk for adults via inhalation and dermal absorption as well.

scholarly journals Multi-Approach Assessment for Stress Evaluation in Rainbow Trout Females, Oncorhynchus mykiss (Walbaum, 1792) from Three Different Farms during the Summer Season

Animals ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1810
Author(s):  
Paul Uiuiu ◽  
Călin Lațiu ◽  
Tudor Păpuc ◽  
Cristina Craioveanu ◽  
Andrada Ihuț ◽  
...  
Keyword(s):  
Rainbow Trout ◽  
Oncorhynchus Mykiss ◽  
Biochemical Parameters ◽  
Principal Component ◽  
Environmental Parameters ◽  
Blood Parameters ◽  
Summer Season ◽  
Farmed Fish ◽  
Blood Profile ◽  
Blood Biochemical

Blood biochemistry parameters are valuable tools for monitoring fish health. Their baseline values are still undefined for a multitude of farmed fish species. In this study, changes in the blood profile of rainbow trout females (Oncorhynchus mykiss) from three farms were investigated using different biomarkers during the summer season. In the given context, the main water physicochemical parameters were investigated and twelve biochemical parameters were measured from blood samples of rainbow trout reared in the Fiad, Șoimul de Jos, and Strâmba farms. We selected these farms because the genetic background of the rainbow trout is the same, with all studied specimens coming from the Fiad farm, which has an incubation station. Forty-five samples were collected monthly (May to August) throughout summer to observe the changes in the blood profile of rainbow trout. Principal component analysis showed a clear separation both among the studied farms and months. Furthermore, significant correlations (p < 0.05) between the majority of the biochemical parameters were found, indicating that the environmental parameters can influence several blood parameters at the same time. The present study provides several useful norms for assessing the welfare of rainbow trout, indicating that the relationships among different parameters are important factors in interpreting the blood biochemical profiles.

Heavy metal and essential elements in beers from turkey market: A risk assessment study

2021 ◽  
pp. 096032712199321
Author(s):  
M Charehsaz ◽  
S Helvacıoğlu ◽  
S Çetinkaya ◽  
R Demir ◽  
O Erdem ◽  
...  
Keyword(s):  
Heavy Metals ◽  
Heavy Metal ◽  
Inductively Coupled Plasma ◽  
Hazard Quotient ◽  
Daily Intake ◽  
Hazard Index ◽  
Carcinogenic Risk ◽  
Essential Elements ◽  
Inductively Coupled ◽  
Multiple Heavy Metals

In this study, the level of arsenic (As), lead (Pb) and cadmium (Cd) and also essential elements in beer samples consumed in Turkey were investigated using the inductively coupled plasma mass spectrometry (ICP-MS) method. The heavy metal-induced non-carcinogenic and carcinogenic risks were calculated. For essential elements, the calculated estimated daily intake of iron (Fe), copper (Cu), selenium (Se) and cobalt (Co) from beer consumption were compared with their toxicity reference values. Tukey post-hoc test showed that As was found at a significantly higher level when compared to Pb. Also, a significant correlation was found between As level and alcohol by volume percent. All samples had a hazard quotient and hazard index <1, indicating no non-carcinogenic risk from exposure to single or multiple heavy metals. Some samples exceeded the threshold limit of acceptable cancer risk for As in the high beer consumer group. This assessment showed that in addition to health implications based on the alcohol content of beer, there might be a carcinogenic risk associated with the heavy metals content of these beverages.

Determination of multiple organochlorine pesticide residues in shrimp using modified QuEChERS extraction and gas chromatography

2018 ◽  
Vol 16 (1) ◽  
pp. 81-93
Author(s):  
MDH Prodhan ◽  
SN Alam
Keyword(s):  
Gas Chromatography ◽  
Organochlorine Pesticide ◽  
Pesticide Residues ◽  
Limit Of Detection ◽  
Residue Analysis ◽  
Limit Of Quantification ◽  
Modified Quechers ◽  
Endosulfan Sulphate ◽  
Organochlorine Pesticide Residues

Determination of organochlorine pesticide residues in shrimp is very important to ensure the consumer’s safety and to fulfill the importer’s demand. Therefore, a simple and efficient multiple organochlorine pesticide residues analytical method using quick, easy, cheap, effective, rugged and safe (QuEChERS) extraction technique and Gas Chromatography coupled with Electron Capture Detector (ECD) has been developed and validated for the determination of 19 organochlorine pesticides (α- BHC, δ- BHC, β- BHC, γ- BHC, Heptachlor, Aldrin, Heptachlor Epoxide, γ- Chlordane, α- Chlordane, α- Endosulfan, 4,4 DDE, Dieldrin, Endrin, 4,4 DDD, β- Endosulfan, 4,4 DDT, Endosulfan sulphate, Methoxychlor, and Endrin Ketone) in shrimp. The method was validated by evaluating the accuracy, precision, linearity, limit of detection (LOD) and limit of quantification (LOQ). The average recoveries of the selected pesticides ranged from 84% to 106% with RSDr ≤ 14% in four fortification levels of 0.05, 0.1, 0.2 and 0.3 mg kg-1. The linearity was ≥ 0.996 for all of the selected pesticides with matrix matched calibration standards. The LOD ranged from 0.003 to 0.009 mg kg-1 and the LOQ was 0.05 mg kg-1. This method was applied successfully for the residue analysis of 40 shrimp samples collected from different regions in Bangladesh.SAARC J. Agri., 16(1): 81-93 (2018)

Gas Chromatography/Principal Component Similarity System for Detection ofE. coliandS. aureusContaminating Salmon and Hamburger

1999 ◽  
Vol 47 (2) ◽  
pp. 576-583 ◽  
Author(s):  
S. Nakai ◽  
Z. H. Wang ◽  
J. Dou ◽  
S. Nakamura ◽  
M. Ogawa ◽  
...  
Keyword(s):  
Gas Chromatography ◽  
Principal Component

scholarly journals VALIDATION AND ANALYSIS OF DIALLYL DISULFIDE AND DIALLYL TRISULFIDE IN GARLIC (ALLIUM SATIVUM L.) USING GAS CHROMATOGRAPHY

2020 ◽  
pp. 163-166
Author(s):  
HARMITA HARMITA ◽  
HERMAN SURYADI ◽  
LIDWINA DEVIANI LIKASA
Keyword(s):  
Gas Chromatography ◽  
Allium Sativum ◽  
Limit Of Detection ◽  
Diallyl Disulfide ◽  
Diallyl Trisulfide ◽  
Ionization Detector ◽  
Limit Of Quantification ◽  
Flame Ionization ◽  
Precision Limit ◽  
Optimized Conditions

Objective: The purpose of this research was to optimize and validate a method for measuring the levels of diallyl disulfide (DADS) and diallyl trisulfide(DATS) in garlic and single clove garlic.Methods: The analysis was performed using gas chromatography (GC) equipped with an HP-1 column and a flame ionization detector. The initialcolumn temperature was set at 140°C and increased at 1°C/min to 180°C. The injector and detector temperatures were set to 200°C, the carrier gasflow rate was 0.80 mL/min, and the injection volume was 1.0 μL. The optimized conditions of analysis were then validated which included selectivity,linearity, accuracy, precision, limit of detection (LOD), and limit of quantification (LOQ).Results: Using the validated assay and a concentration range of 0.5–20 μg/mL, the coefficient of correlation (r) for DADS was 0.9999 and the LODand LOQ for DADS were 0.3063 μg/mL and 1.0210 μg/mL, respectively. Using the validated assay and a concentration range of 0.5–20 μg/mL, thecoefficient of correlation for DATS was 0.9999 and the LOD and LOQ for DATS were 0.1986 μg/mL and 0.6621 μg/mL, respectively. The percentage ofrecovery was in the range of 98.05–101.76% and coefficient of variation ≤ 2%.Conclusion: This GC method accurately measures the levels of DADS and DATS in garlic.

scholarly journals Risk Assessment of Chemical Contaminants Ingestion with Nutrition of Children Aged 3–6 Years from the City of Kazan

Proceedings ◽  
2018 ◽  
Vol 6 (1) ◽  
pp. 9
Author(s):  
Suryana Fomina ◽  
Nataliya Stepanova ◽  
Ilyuza Galimullina ◽  
Lyudmila Obukhova
Keyword(s):  
Child Nutrition ◽  
Hazard Quotient ◽  
Hazard Index ◽  
Carcinogenic Risk ◽  
Food Groups ◽  
Chemical Contaminants ◽  
Carcinogenic Effects ◽  
The Central Nervous System ◽  
The City ◽  
Second Period

The analysis of the intake of chemicals such as cadmium (Cd), lead (Pb), arsenic (As), and mercury (Hg) in the diet of children aged 3–6 years from the city of Kazan for the periods 2007–2010 and 2011–2014 was carried out. The study of actual child nutrition was performed by questionnaire and time-weight methods. The calculation of daily doses was made with the account of regional exposure factors at the 95th percentile level. The non-carcinogenic risk from the exposure to methylmercury with basic food groups at the level of the 95th perc made 3.89 and 3.33 for both periods, 10.67—for arsenic in the first period, being unacceptable (hazard quotient (HQ) > 1). In 2007–2010, the central nervous system (CNS), the hormone system (HS), the immune system (IS), and the development (hazard index (HI) = 15.75, 12.87, 11.72, and 4.03) were exposed to the highest toxic effect, and in 2011–2014, the CNS and the development (HI = 4.02 and 3.98). The risk of developing non-carcinogenic effects for these systems (64%–91%) was mainly due to contamination of foods with As for the first period, and to the intake of Pb (46%–57%) for the second period. The value of the total individual carcinogenic risk (ICR Cd, Pb, As), for the second period 1.69 × 10 5 corresponded to the maximum allowable level. In 2007–2010, the total ICR was 2.45 × 10 4 which is an unacceptable level for the general population. The major contribution to the total ICR due to the intake of contaminated foods was made by As (92.55%) in the first period, and by Cd (79.93%) in the second period. The peculiarities of the child body (the amount of chemicals ingested per kilogram of body weight is higher in children than in adults) determine the potential risk and are responsible for high vulnerability on exposure to chemicals and the development of adverse effects.

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