scholarly journals Reference limits for routine haematological measurements in pre-school and school-children living at an urban area

2004 ◽  
Vol 23 (1) ◽  
pp. 59-64
Author(s):  
Daniela Ardalic ◽  
Slavica Spasic ◽  
Brankica Gulan

The aim of this study is to estimate 95% reference limits for eight haematological constituents of blood in order to provide medically reliable evaluation of haematological laboratory results. Blood counts were performed using an automated haematology analyzer (Cell-Dyn 1500) on capillary blood samples from 1918 children (1?16 years old) residing in a region of Novi Beograd. Physiological variations corresponding to age and sex were studied as the most important factors affecting biological variation in haematological constituents of blood. Children were divided in four groups according to age: 1?3 yrs (281 boys and 241 girls), 4? 6 yrs (196 boys and 150 girls), 7?12 yrs (322 boys and 368 girls) and 13 ?16 yrs (174 boys and 186 girls). In this study all investigated parameters were not sex dependent until the age of 13. Boys between ages 13 and 16 years have higher mean values of haemoglobin (143.81 ? 13.40 g/L) and red blood count (4.81 ? 0.49 ? 1012/L), but lower MCV (86.6 ? 5.27 fL) than girls in same age group (136.81 ? 13.42 g/L, 4.57 ? 0.47 ? 1012/L and 88.0 ? 6.96 fL respectively). There was no significant difference according to sex in the oldest group for mean values of haematocrit (boys 0.42 ? 0.049 L/L and girls 4.57 ? 0.47 L/L), MCH (boys 29.9 ? 1.92 pg and girls 30.2 ? 1.96 pg), MCHC (boys 345.9 ? 18.4 g/L and girls 342.2 ? 19.7 g/L), platelet (boys 219.8 ? 49.6 ? 109/L and girls 225.3 ? 59.2 ? 109/L) and white blood count (boys 8.0 ? 2.60 ? 109/L and girls 8.01 ? 2.08 ? 109/L). Haemoglobin level, red blood count, haematocrit, MCV, MCH and MCHC increased with age. Levels of platelet count and white blood count decreased with age.

2016 ◽  
Vol 22 (1) ◽  
Author(s):  
Kerem Doğa Seçkin ◽  
Mehmet Fatih Karslı ◽  
Burak Yücel ◽  
Elif Akkaş Yılmaz ◽  
Murat Öz ◽  
...  

<p>OBJECTIVE: The aim of the study was to determine whether it is possible to differentiate submucosal fibroids before interventional procedures based on mean platelet volume (MPV), in reproductive-age patients presenting with endometrial thickening and abnormal uterine bleeding.<br />STUDY DESIGN: This study included 581 reproductive-age women who underwent diagnostic procedures (curettage or operative hysteroscopy) and were subsequently divided into two groups based on clinico-pathological findings. The first group included those with benign endometrial pathology (control group, n=438), and the second group consisted of those with submucosal leiomyomas (n=143). The demographic characteristics and complete blood count (CBC) data of these patients were collected retrospectively, and comparisons were made between groups.<br />RESULTS: No statistically significant difference was found between the groups according to demographic features and CBC parameters such as hemoglobin levels and white blood count (p&gt;0,05). Platelet counts were significantly higher and MPV values were significantly lower in submucosal leiomyoma patients compared with the control subjects (p&lt;0,05).<br />CONCLUSIONS: MPV may be a useful predictive marker when differentiating submucosal leiomyoma from other benign causes of abnormal uterine bleeding. The ability to predict the possibility of the presence of submucosal leiomyoma before surgery can assist in determining the most appropriate type of invasive procedure.</p>


2003 ◽  
Vol 3 (2) ◽  
pp. 35-41 ◽  
Author(s):  
Enver Suljević ◽  
Muhamed Fazlić ◽  
Jozo Čorić ◽  
Emina Kiseljaković

Research on the parameters of full blood count and differential white blood count is included in the program of all medical laboratories of primary, secondary and tertiary health care levels. Today, all haematological tests are exclusively performed on the haematology analyzers. Automation of haematology laboratories is a result of the huge requires for haematological test performing, timely issuing of the haematological findings, and possibility of the usage of modern techniques.This work is an evaluation of laser haematology analyzer Cell-Dyn 3700 SL. It investigates the reliability of test results throughout the following parameters: precision, accuracy, sensitivity and specificity of determination methods. It also explores the influence of sample transferring and correlation with haematology analyzer MAXM Retti. Haematology parameters that have been investigated are: white blood cell (WBC), neutrophils (NEU), lymphocytes (LXM), monocytes (MONO), eosinophils (EOS), basophils (BASO), red blood cells (RBC), haemoglobin (HGB), haematocrit (HCT), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCHC) red cell distribution width (RDW), platelet (PLT), mean platelet volume (MPV), plateletocrit (PCT), and platelet distribution width (PDW).The results confirms that precision of analyzer fulfils the reproducibility of testing parameters: WBC, RBC, HGB, MCV, MCH, MCHC, and PLT. Correlation coefficient values (r) gained throughout the statistical analysis, that is linear regression results obtained throughout the comparison of two analyzers are adequate except for MCHC (r = 0.64), what is in accordance with literature data.Accuracy is tested by haematology analyzer method and microscopic differentiating method. Correlation coefficient results for granulocytes, lymphocytes and monocytes point the accuracy of methods. Sensitivity and specificity parameters fulfil the analytical criteria.It is confirmed that haematology analyzer Cell-Dyn 3700 SL is reliable for the determination of full blood count in everyday work. Analyzer and its program for differential white blood count can be used for the research and separation of normal and pathological blood counts with addition of microscopic methods confirming distribution or morphologic changes of leukocytes.


Author(s):  
Isha Chhabra ◽  
Harpreet Kaur ◽  
Shruti Jain

Comfortable foods are chemically processed and made from heavily refined ingredients and artificial additives. These foods are manufactured and distributed in ways that encourage consumption. This study focused on adolescents since they have greater access to comfortable foods, are more free and lesser concerned for their health. Fewer studies have been conducted on adolescents but in present scenario they are more inclined towards unhealthy eating behaviors. Therefore, the present study after careful considerations was attempted to assess the consumption of comfortable foods by urban adolescents in different socio-economic categories. Two hundred subjects in the age group of 16 to 18 years were purposely selected in equal number in the ratio of 1:1 of boys and girls. Findings revealed that majority belonged to high socioeconomic status whereas 52% boys and 44% girls belonged to low socioeconomic status. Respondents from the entire income category mostly consumed comfortable foods because it was either liked by them or they found it good in taste. Consumption of all the comfortable foods was found to be significantly (p≤0.05, p≤0.01) higher in adolescents who had high income and greater access of these food products.  Significant difference was observed in the mean values of consumption of comfortable foods by all the adolescents in different socioeconomic categories.


2016 ◽  
Vol 05 (01) ◽  
pp. 028-035
Author(s):  
Malamoni Dutta ◽  
H Bayan

Abstract Background and aims: The uterus is subjected to a wide range of normal variation in both its anatomy and physiology e.g. the changes of childhood to puberty and into the reproductive years, the variations of menstrual cycle, the changes consequent to pregnancy and parturition and fmally regression associated with menopause and postmenopausal years. It is a very important organ of female reproductive system and is subjected to investigation for size, shape and position in cases of infertility. The study of normal morphological architecture is of prime importance to have the basic knowledge of the various pathological entities. Materials and methods : 30 samples each from reproductive and postmenopausal women were collected from fresh unembalmed human cadavers. Biometrical values of the two different groups were recorded and statistically analyzed for Mean. The 'z' test was employed to find out the significant difference between mean values of length, breadth, thickness and weight. Results: The Length, Breadth , Thickness and weight of uterus in Reproductive age group and Post - menopausal age group differ significantly. The length, breadth, thickness and weight ranged from 6.2-9.0 em, 4.9-6.1 em, 2-3.5 em, 35.4-73 gm respectively in reproductive age group. In the postmenopausal group the length, breadth, thickness and weight ranged from 3.8-6.5 em, 1.8-5.0 em, 1-2.3 em, 18-40.0 gm respectively. Conclusion: A clear conception of the age related morphological changes ofuterus is a prerequisite for the radiologists for pelvic imaging and for clinicians for diagnosis and management of various diseases like benign and malignant neoplasms and infertility.


Biomedicine ◽  
2021 ◽  
Vol 41 (4) ◽  
pp. 855-858
Author(s):  
G. Vaishnavi ◽  
S. Dinesh Kumar ◽  
G. Mohan Kumar ◽  
Kirupa K. ◽  
G. Tharani ◽  
...  

Introduction: Upper cross syndrome (UCS) occurs when the muscle in the neck, shoulders, and chest become deformed usually as a result of poor posture. The aim of the study is to analyse the effect of McKenzie’s method of exercise to treat upper cross syndrome associated with cervicogenic headache. Materials and Methods: This experimental study was conducted in outpatient department physiotherapy A.C.S. Medical College and Hospital. Fifty subjects were selected for the study of the age group between 20 to 50 years of both male and female sex. Duration of this study was about 3 months. Each patient was trained about three session per week, 30 minutes per session. The session included McKenzie’s method of exercise to improve the shoulder and neck movements and postural corrections of the subjects. The outcome measure done using visual analogue scale (VAS) for cervicogenic headache and upper cross syndrome questionnaire (UCS). Results: The results on comparing upper cross syndrome questionnaire score and Visual Analog Scale score showed that between the pre-test (4.93) and post-test (3.43) mean values with group McKenzie’s exercise showed highly significant difference. Thus, it is appropriate that McKenzie’s method of exercise to treat upper cross syndrome associated with cervicogenic headache is effective.


Author(s):  
Vinaykumar R. H. ◽  
Gleeja V. L. ◽  
Gleeja V. L. ◽  
Gleeja V. L. ◽  
Gleeja V. L. ◽  
...  

A large variation in the gestation length can be expected when the gestation is calculated from the day of mating to birth. The present study was designed to assess the influence of different factors like litter size, breed, parity and age on gestation length in bitches. A total of 89 small sized bitches of different breeds having different age, parity and body weight, were selected for the study. The mean age, body weight and parity of the animals included in the present study were 3.00 ± 0.15 years (1 to 8 years), 9.9 ± 0.25 Kg (6 to 15kg) and 1.14 ± 0.10 (0-4th parity) respectively. The mean gestation lengths observed in different small sized breeds were 60.68 ± 0.55, 59.82 ± 0.54, 60.78 ± 1.74, 58.83 ± 1.35 and 58.17 ± 0.74 in the Pug, Beagle, Dachshund, French Bulldog and the Spitz, respectively. The mean litter size in the study was 4.34 ± 0.13 with a range of 2-8. The mean gestational length in animals having ? 3 litter size was 60.83 ± 0.64 days and 59.90 ± 0.43 days in animals having >3 litter size. Age limit of the animals ranged from 1 to 8 years with a mean of 3 ± 0.15 years. The mean gestation length in bitches aged ?3 years was 60.21 ± 0.23 days (n=63) and this was 60.15 ± 0.3 (n=26) days in bitches in the >3 years group. Mean gestational length observed in nulliparous bitches was 60.86 ± 0.4 days (n=29), while in multiparous bitches it was 59.90 ± 0.5 days (n=60). From the present investigation it could be concluded that no significant difference exists in gestational length between different breeds, litter size, age group and parity.


Author(s):  
Majid ZARRIN KAFSH ◽  
Gholam Hossein HALVANI ◽  
Hossein FALLAH ◽  
Mahsa ASGARI

Introduction: Creation of anthropometric database in any age group is one of the most important issues in designing and manufacturing of used equipment. The aim of this study was to determine the anthropometric characteristics of nurses of kindergartens and preschools in Isfahan in the age range of 2 to 6 years and to create an information reference.Materials and Methods: In this applied study, 700 healthy male and female boys were selected randomly from cluster sampling from nursery schoolchildren and preschools in Isfahan city. 36 anthropometric measurements of them were cross-sectional in the academic year 1396 to 1397. And indicators and statistical percentiles (5.50 and 95) were extracted.Results: Statistical indexes and percentiles were presented as an anthropometric database in 5 age groups and in two sex groups. Age and sex were influenced by most anthropometric variables and significant difference (P <0.05). .Conclusion: The age and sex are two factors affecting anthropometric variables. Therefore, it is necessary to use the anterpometric database of the same age group and gender in the design of the equipment.


2021 ◽  
Vol 15 (Supplement_1) ◽  
pp. S225-S226
Author(s):  
N A Cohen ◽  
E Kliper ◽  
N Zamstein ◽  
T Ziv-Baran ◽  
A Ben Tov ◽  
...  

Abstract Background Early diagnosis of inflammatory bowel diseases (IBD) is associated with improved response to treatment and disease outcomes. Predicting patients at risk of developing symptomatic IBD would provide a window of opportunity to treat patients before irreversible bowel damage is caused. Our aim is to determine whether there is a pattern of change in use of health resources, medications and laboratory results in the years prior to diagnosis. Methods This is a retrospective study performed using electronic medical records (EMR) of Maccabi Health Services (MHS) which insures 25% of the Israeli population with a nationwide distribution. Data was extracted using MDClone (MDClone Ltd). IBD patients ≥ 16 years of age and minimum of 5 years follow up were identified by entry into the MHS IBD registry and included in the study. Demographic, clinical, medication and laboratory data was collected. Generalized estimating equation (GEE) model was applied to study trends and compare between years. Results A total of 5643 IBD patients were included. Of these, 3039 (53.8%) had Crohn’s disease (CD), 2322 (41.1%) had ulcerative colitis (UC) and 282 (5%) had indeterminate colitis (IC). The mean age of the total IBD population at inclusion to the registry was 39.3 ± 16.5 years. Overall, CD patients had significantly increased visits to general practitioners, emergency rooms and admissions compared to UC patients (33.2 vs 30, p&lt;0.0001; 0.2 vs 0.17, p&lt;0.0001 and 0.88 vs 0.71, p&lt;0.0001, respectively). CD and IC patients had similar patterns of medical professional/institution visits. Laboratory parameters such as haemoglobin and mean corpuscular volume showed significant decrease and white blood count, platelets and c-reactive protein showed significant increase in mean values primarily in the 2 years prior to diagnosis with stable values prior to that (p&lt;0.0001 for all parameters). In contrast, parameters such as creatinine, total protein, albumin and calcium showed earlier significant and progressive decreases in mean values starting 5 years prior to diagnosis (p&lt;0.0001 for all parameters) (Figure 1). Use of medications such as nonsteroidal anti-inflammatory drugs, etanercept, steroids, proton pump inhibitors and antibiotics significantly increased in the 2 years prior to IBD registry entry (P&lt;0.0001 for all). Conclusion There are clear changes from baseline in uptake of medical resources, medication usage and laboratory results in the 5 years prior to IBD diagnosis. Parameters such as creatinine and albumin give earlier signal than others. This data may allow the development of an algorithm stratifying patients into those who need more intensive follow-up or investigations to enable earlier disease diagnosis.


2019 ◽  
pp. 1-4
Author(s):  
Derya Ece Iliman ◽  
Ibrahim Karaca ◽  
Levent Yasar ◽  
Keziban Dogan ◽  
Raziye Kıcık Calıskan

Objective: In this study we aimed to compare blood count parameters such as; mean platelet volume (MPV), platelet count (PC), and platelet distribution width (PDW), white blood count (WBC), hemoglobin (HMG), hematocrit (HCT), lymphocyte (LYM ), neutrophil (NEU), PC/MPV, PC/LYM, PC/WBC, NEU/LYM rates; between healthy pregnant women and pregnant women with Gestational Diabetes Mellitus (GDM) whether these parameters have a predictive value of GDM. Methods: A retrospective case control study was performed and a total of 202 pregnant women including 78 pregnant women with GDM (38.6%) and 124 healthy pregnant women (61.4%; the control group) were fallen under the study. Prior medical histories had no particularity. Results: The result of compared parameters between GDM and Control Groups; there was no significant difference between any variables except age (p=0.024; p<0.05). Conclusion: If blood samples are evaluated under healthy conditions ( rapidly collection, transfer and studying) we concluded that blood count parameters would not be useful for predicting the diagnosis of GDM.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Hyewon Kim ◽  
Dong Jun Kim ◽  
Won Ho Chung ◽  
Kyung-Ah Park ◽  
James D. K. Kim ◽  
...  

AbstractThe use of virtual reality (VR) in the treatment of psychiatric disorders is increasing, and cybersickness has emerged as an important obstacle to overcome. However, the clinical factors affecting cybersickness are still not well understood. In this study, we investigated clinical predictors and adaptation effect of cybersickness during VR application in highly stressed people. Eighty-three healthy adult participants with high stress level were recruited. At baseline, we conducted psychiatric, ophthalmologic, and otologic evaluations and extracted physiological parameters. We divided the participants into two groups according to the order of exposure to VR videos with different degrees of shaking and repetitively administered the Simulator Sickness Questionnaire (SSQ) and the Fast Motion sickness Scale (FMS). There was no significant difference in changes in the SSQ or the FMS between groups. The 40–59 years age group showed a greater increase in FMS compared to the 19–39 years age group. Smoking was negatively associated with cybersickness, and a high Positive Affect and Negative Affect Schedule score was positively associated with cybersickness. In conclusion, changing the intensity of shaking in VR did not affect cybersickness. While smoking was a protective factor, more expression of affect was a risk factor for cybersickness.


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