scholarly journals Echocardiographic evaluation of ventricular septal defect haemodynamics

2007 ◽  
Vol 135 (9-10) ◽  
pp. 541-546
Author(s):  
Vesna Miranovic
Keyword(s):  
Ventricular Septal Defect ◽  
Pulmonary Artery ◽  
Body Surface ◽  
Septal Defect ◽  
Left Ventricular ◽  
The Body ◽  
Control Group ◽  
Healthy Children ◽  
And Control ◽  
The Relationship

Introduction Ventricular septal defect (VSD) is an opening in the interventricular septum. 30-50% of patients with congenital heart disease have VSD. Objective The aim of the study was to determine the dependence of the left ventricular diastolic dimension (LVD), left ventricular systolic dimension (LVS), shortening fraction (SF), left atrium (LA), pulmonary artery truncus (TPA) on the body surface and compare their values among experimental, control and a group of healthy children. Values of maximal systolic gradient pressure (Pvsd) of VSD were compared with children from one experimental and control group. Method Children were divided into three groups: experimental (32 children with VSD that were to go to surgery), control (20 children with VSD who did not require surgery) and 40 healthy children. Measurements of LVD, LVS, SF, LA, TPA were performed in accordance to recommendations of the American Echocardiographic Association. The value of Pvsd was calculated from the maximal flow velocity (V) in VSD using the following formula: Pvsd=4xV? (mm Hg). Results For children from the experimental group, the relationship between the body surface and the variability of the LVD was explained with 56.85%, LVS with 66.15%, SF with 4.9%, TPA with 58.92%. For children from the control group, the relationship between the body surface and the variability of LVD was explained with 88.8%, LVS with 72.5%, SF with 0.42%, PA with 58.92%. For healthy children, the relationship between the body surface and the variabilitiy of the LVD was explained with 88.8%, LVS with 88.78%, SF with 5.25% and PA with 84.75%. There was a significant statistical difference between average values of Pvsd in the experimental and control group (p<0.02). Conclusion The presence of the large VSD has an influence on the enlargement of LVD, LVS, SF, TPA. The enlargement of the size of the pulmonary artery depends on the presence of VSD and there is a direct variation in the magnitude of the shunt. There is a relationship and significant dependence of the LVS and LVD on the body surface. There is no statistically significant dependence between SF and body surface.

scholarly journals DYNAMICS OF HEART RATE VARIABILITY IN CHILDREN OPERATED FOR VENTRICULAR SEPTAL DEFECT IN ТНЕ PROCESS OF SANATORIAL SPA TREATMENT

2020 ◽  
Vol 26 (3) ◽  
pp. 68-70
Author(s):  
N. N. Kaladze ◽  
А. Уи. Iushchenko ◽  
V. N. Lukyanenko ◽  
М. Е. Kutkin
Keyword(s):  
Heart Rate ◽  
Heart Rate Variability ◽  
Ventricular Septal Defect ◽  
Septal Defect ◽  
Medical Rehabilitation ◽  
Control Group ◽  
Healthy Children ◽  
Time Analysis ◽  
Nordic Walking ◽  
Significant Difference

The purpose of the study is to study the effectiveness of medical rehabilitation in children operated on for a ventricular septal defect, based on the dynamics of heart rate variability indicators. Material and methods of research. Heart rate variability was evaluated in 75 children operated on for ventricular septal defect. The control group (CG) consisted of 30 healthy children. The effectiveness of medical rehabilitation was assessed by the dynamics of heart rate variability indicators. Children of the 1st group (20 people) took the cardiometabolic drug Elkar at a dose of 30 mg/kg/day for 1 month. With children of the 2nd group (20 people) for 3 months, Nordic walking classes were held (NW). In addition, children of the 2nd group received the drug Elkar for 1 month (30 mg/kg). Results. According to the time analysis of heart rate variability, operated children had significantly lower values of SDNN 82 [69;103] (p<0.001), SDANNi 50.5 [39;87] (p<0.05), SDNNi 69.5 [54;80] (p<0.05), rMSSD 50.5 [39;87] (p<0.05), pNN50 % 18.4 [6.7;28.3] (p<0.05) lower power in the high-frequency range of the spectrum (p<0.001) and a change in the vegetative balance towards the predominance of the sympathetic division of the autonomic nervous system (LF/HF=3.16, p=0.009) than in the control group. After the treatment, there was no reliable HRV dynamics in children who received Elcar. There was a significant difference between SDNN and rMSSD with KG. In the second group, there was a significant increase in HRV according to SDNN data by 37.7 % (p<0.01), SDANNi by 45.6 % (p<0.05), rMSSD by 6.5 % (p<0.05), pNN50 % by 32.7 % (p<0.05). The difference in indicators with CG is leveled. Conclusions. In children operated on for VSD, there was a decrease in the parameters of the time analysis of HRV in comparison with healthy peers (p<0.05). The combined use of Nordic walking and Elkar have a normalizing effect on the HRV, causing a decrease in the tension of the Central circuit of heart rate regulation, significantly increasing the parasympathetic effect on the heart rate.

Abstract 13029: Sonothrombolysis Improves Left Atrial Pressure and Volume in Patients With ST Elevation Acute Myocardial Infarction

Circulation ◽  
2020 ◽  
Vol 142 (Suppl_3) ◽  
Author(s):  
Hsu Po Chiang ◽  
Miguel Aguiar ◽  
Bruno Tavares ◽  
Wilson Mathias ◽  
Bruno C Borges ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Left Atrial ◽  
Therapy Group ◽  
Left Ventricular ◽  
The Body ◽  
Control Group ◽  
Mechanical Index ◽  
Control Groups ◽  
St Elevation ◽  
And Control

Introduction: Preclinical studies in ST elevation myocardial infarction (STEMI) indicate that high mechanical index impulses guided with transthoracic diagnostic ultrasound associated with intravenously administered microbubbles results in the dissolution of the thrombus (sonothrombolysis), improving coronary microcirculation and epicardial coronary recanalization rate. Hypothesis: Left atrial (LA) echocardiographic parameters are compromised in STEMI and can be accurately measured by two-dimensional echocardiography. To study the effect of sonotrombolysis on the LA pressure and volume we propose our study. Methods: A total of 100 patients were randomized, 50 for the control group and 50 for the therapy group. Echocardiographic analysis of LA pressure and volume were performed immediately before and after percutaneous coronary intervention (PCI), 72 hours, 1 month and 6 months of follow-up. LA pressure was classified in normal or elevated, depending on the grade of left ventricular diastolic disfunction (DD): normal diastolic function and DD grade 1 have normal LA pressure, and DD grades 2 and 3 have elevated LA pressure, according to the American and European guideline. LA volume was evaluated by Simpson method and indexed to the body surface area. Results: The LA pressure and volume had lower values in the therapy group after 6 months of PCI. The comparison of LA pressure between the therapy and control groups respectively was: before PCI (72% vs. 70% normal; 28% vs. 30% elevated; p=0.826), after PCI (68% vs. 65% normal; 32% vs. 35% elevated; p=0.777), 72 hours (75% vs. 62% normal; 25% vs. 38% elevated; p=0.147), 1 month (68% vs. 52% normal; 32% vs. 48% elevated; p=0.123) and 6 months (84% vs. 64% normal; 16% vs. 36% elevated; p=0.035). The comparison of LA volumes between the therapy and control groups respectively was: before PCI (19.0±6.2 vs. 22.4±9.8 ml/m 2 ; p=0.061), after PCI (22.8±7.9 vs. 24.4±12.1 ml/m 2 ; p=0.469), 72 hours (25.9±8.5 vs. 26.4±12.7 ml/m 2 ; p=0.815), 1 month (27.2±8.3 vs. 29.1±13.1 ml/m 2 ; p=0.410) and 6 months (26.7±7.5 vs. 33.1±14.9 ml/m 2 ; p=0.013). Conclusions: The use of sonothrombolysis as adjuvant therapy in STEMI patients results in better values of LA pressure and volume, demonstrating the benefit of using this new therapy.

The effects of surgically induced right bundle branch block on left ventricular function after closure of the ventricular septal defect

2008 ◽  
Vol 18 (4) ◽  
pp. 430-436 ◽  
Author(s):  
Thais A. L. Pedersen ◽  
Niels H. Andersen ◽  
Mette R. Knudsen ◽  
Thomas D. Christensen ◽  
Keld E. Sørensen ◽  
...  
Keyword(s):  
Ventricular Septal Defect ◽  
Left Ventricular Function ◽  
Right Bundle Branch Block ◽  
Septal Defect ◽  
Left Ventricular ◽  
Surgical Correction ◽  
Control Group ◽  
Bundle Branch Block ◽  
Surgical Closure ◽  
Control Subjects

AbstractObjectiveTo determine the long-term significance of right bundle branch block on left ventricular systolic and diastolic function in children subsequent to surgical closure of ventricular septal defect.MethodsWe studied 26 children who underwent surgical closure of a ventricular septal defect 11 ± 2 years postoperatively by use of conventional and tissue Doppler echocardiography, comparing the findings to those obtained from a control group. Of those having surgical correction 14 had postoperative right bundle branch block.ResultsIrrespective of the presence of right bundle branch block, the peak systolic velocity of the mitral ring was lower in those undergoing surgical correction, with values of 5.2 ± 1.4 cm/s in those with right bundle branch block, 5.4 ± 1.2 cm/s in those without right bundle branch block after surgical correction, and 6.6 ± 1.0 cm/s in the control subjects (p < 0.01). In terms of diastolic function, the early septal velocity of transmitral inflow divided by the early diastolic mitral annular velocity was significantly higher in children with right bundle branch block, at 12 ± 3.0 cm/s compared to 8.4 ± 1.5 cm/s in the control subjects (p < 0.01), but not significantly higher in the children without right bundle branch block after correction compared to the control group. The fractional shortening percentage was similar in both patients and control subjects. The changes noted in left ventricular function were not significantly related to age at surgery, the period of follow-up, or the surgical method.ConclusionsSystolic long axis function is significantly reduced in children after surgical closure of ventricular septal defects, irrespective of the presence of right bundle branch block. Diastolic dysfunction, in contrast, was observed primarily in children with post-operative right bundle branch block.

scholarly journals Investigation of the Relationship between Parental Mental Disorders and Autism among the Children of West Azerbaijan -Iran

2020 ◽  
Vol 10 (1) ◽  
pp. 59
Author(s):  
Arezou Kiani Equal ◽  
Javad Rasouli ◽  
Sahar Kiani
Keyword(s):  
Mental Disorders ◽  
Communication Disorders ◽  
Repetitive Behaviors ◽  
Control Group ◽  
Healthy Children ◽  
Control Groups ◽  
Mental Diseases ◽  
West Azerbaijan ◽  
And Control ◽  
The Relationship

Background: Autism disorders have increased over the last years. Autism is a neurological growth disorder associated with social communication disorders, growth retardation, and repetitive behaviors, along with serious consequences for children and families. The purpose of this research was to evaluate the relationship between parental mental disorders and autism among the children of West Azerbaijan Province. Methods: This research was a case-control study in which the case group subjects were selected among the parents with autistic children and control group subjects were selected among the relative parents with healthy children and non-relative parents with healthy children. Both case and control groups were matched in terms of gender, living place, and age of children. Finally, the data were analyzed using SPSS-16 (Chicago, IL, USA) software. Results: The current research results revealed that the frequency of mental diseases, including obsessive-compulsive, inter personality sensitivity, depression, anxiety, hostility, phobia, paranoid ideation, and psychotic disorder are different in fathers and mothers of the case and control groups. As Pvalue was lower than 0.05 in all scales, there was a significant relationship between the mental diseases of parents and the history of mental disorders in relatives and autism. Conclusion: The prevalence of mental disorders in relatives and having a medical history can be a warning sign of autism in children.

scholarly journals The assessment of liver fibrosis in children with obesity on two methods: transient and two dimensional shear wave elastography

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Cristina Oana Mărginean ◽  
Lorena Elena Meliţ ◽  
Dana Valentina Ghiga ◽  
Maria Oana Săsăran
Keyword(s):  
Liver Stiffness ◽  
Shear Wave Elastography ◽  
Tertiary Hospital ◽  
Normal Weight ◽  
The Body ◽  
Control Group ◽  
Study Group ◽  
Healthy Children ◽  
Laboratory Parameters ◽  
And Control

AbstractThe aim of this study was to assess the liver stiffness values in children with obesity versus healthy children on 2D-SWE and TE taking into account different laboratory parameters. We performed a case-control study on 287 children aged between 3 to 18 years, admitted in a Romanian Pediatric Tertiary Hospital, which we divided according to the body mass index (BMI) into two groups: the study group-77 children with obesity, and control group-210 children with normal weight. All children underwent anamnesis, clinical exam, laboratory parameters, ultrasound exam, and elastography. Children with obesity presented higher values of platelets, AST, ALT, and AAR as compared to control group (p = 0.0005/p = 0.0065/p < 0.0001/p < 0.0001). We found no significant differences for APRI between the two groups (p = 0.9827), although the values were higher in children with obesity. Significantly higher values of liver stiffness in children with obesity on both 2D-SWE and TE (p = 0.0314/p < 0.0001) were obtained. Similarly, the velocity values measured by 2D-SWE were also significantly higher in the study group (p < 0.0001). Our findings revealed significantly higher levels of platelets, transaminases, AAR, and liver stiffness values on both TE and 2D-SWE in children with obesity. 2D-SWE and TE might represent useful non-invasive methods for predicting liver impairment associated to pediatric obesity.

scholarly journals ST Segment Body Surface Isointegral Maps in Patients With Arterial Hypertension

2012 ◽  
pp. 35-42
Author(s):  
K. KOZLÍKOVÁ ◽  
J. MARTINKA ◽  
J. BULAS
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Arterial Hypertension ◽  
Body Surface ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
The Body ◽  
Control Group ◽  
Surface Mapping ◽  
St Segment ◽  
Heart Field

In this retrospective study we analysed changes of the ST segment in patients with arterial hypertension using multi-lead body surface mapping of the electric heart field as the ST segment often shows non-specific changes and is influenced by many different conditions. We constructed isointegral maps (IIM) of chosen intervals (the first 35 ms, the first 80 ms, and the whole ST segment) in 42 patients with arterial hypertension (with and without left ventricular hypertrophy) and in the control group involving 23 healthy persons. We analysed the position and values of map extrema. Spatial distribution of voltage integrals was similar in the control group and in the “pure” hypertensives. Patients with the left ventricular hypertrophy exhibited shifts of the integral minima. Despite our expectations, the highest extrema values were found in the control group and not in the left ventricular hypertrophy group. The extrema values were similar in all hypertensives, with or without left ventricular hypertrophy. Differences could be explained neither by the influence of the age, nor by the body habitus.

The use of Body Surface Index as a Better Clinical Health indicators Compare to Body Mass Index and Body Surface Area for Clinical Application

2018 ◽  
pp. 131-136
Author(s):  
Shirazu I. ◽  
Theophilus. A. Sackey ◽  
Elvis K. Tiburu ◽  
Mensah Y. B. ◽  
Forson A.
Keyword(s):  
Surface Area ◽  
Body Surface Area ◽  
Clinical Application ◽  
Body Surface ◽  
Body Height ◽  
Health Indicators ◽  
The Body ◽  
Body Parameters ◽  
The Relationship ◽  
Individual Body

The relationship between body height and body weight has been described by using various terms. Notable among them is the body mass index, body surface area, body shape index and body surface index. In clinical setting the first descriptive parameter is the BMI scale, which provides information about whether an individual body weight is proportionate to the body height. Since the development of BMI, two other body parameters have been developed in an attempt to determine the relationship between body height and weight. These are the body surface area (BSA) and body surface index (BSI). Generally, these body parameters are described as clinical health indicators that described how healthy an individual body response to the other internal organs. The aim of the study is to discuss the use of BSI as a better clinical health indicator for preclinical assessment of body-organ/tissue relationship. Hence organ health condition as against other body composition. In addition the study is `also to determine the best body parameter the best predict other parameters for clinical application. The model parameters are presented as; modeled height and weight; modelled BSI and BSA, BSI and BMI and modeled BSA and BMI. The models are presented as clinical application software for comfortable working process and designed as GUI and CAD for use in clinical application.

Perbandingan Efek Suplementasi Tablet Tambah Darah Dengan Dan Tanpa Vitamin C Terhadap Kadar Hemoglobin Pada Ibu Hamil Dengan Usiakehamilan 16-32 Minggu Di Desa Keniten Kecamatan Mojo Kabupaten Kediri

2017 ◽  
Vol 3 (1) ◽  
pp. 76
Author(s):  
Siti Asiyah ◽  
Dwi Estuning Rahayu ◽  
Wiranti Dwi Novita Isnaeni
Keyword(s):  
Treatment Group ◽  
Vitamin C ◽  
Gestational Age ◽  
Group Treatment ◽  
Sampling Technique ◽  
Hemoglobin Level ◽  
The Body ◽  
Control Group ◽  
Fetal Organ ◽  
And Control

The needed of Iron Tablet in pregnancy was increase than mother who not pregnant.  That  cause of  high metabolism at the pregnancy for formed of  fetal organ and energy. One of effort for prevent anemia in mother pregnant with giving the Iron tablet and vitamin c. The reason of  this research in 4 June – 11 July 2014 is for compare the effect of  iron tablet suplementation with and without vitamin C toward Hemoglobin level in mother pregnant With Gestational Age Of 16-32 Weeks In Desa Keniten Kecamatan Mojo Kabupaten Kediri. This research method using comparative analytical.  Research design type of Quasy Eksperiment that have treatment group and control group. Treatment group will giving by Iron tablet and 100 mg vitamin C, and control group just giving by iron tablet during 21 days. Population in this research are all of mother pregnant with Gestational Age Of 16-32 Weeks with Sampling technique is  cluster random sampling is 29 mother pregnant. Comparison analysis of  iron tablet suplementation effect with and without vitamin C toward Hemoglobin level in mother pregnant With Gestational Age Of 16-32 Weeks, data analysis using Mann Whitney U-test and the calculated U value (44,5) less than U-table (51). So there was difference of iron tablet suplementation effect with and without vitamin C toward Hemoglobin level in mother pregnant With Gestational Age Of 16-32 Weeks Therefore, the addition of vitamin C on iron intake is needed to increase the uptake of iron tablets. When the amount of iron uptake increases, the reserves of iron in the body will also increase, so as to prevent anemia in pregnant women; Keywords : Iron Tablet (Fe), Vitamin C, Hemoglobin level, Mother Pregnant

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