Three-Month Evaluation of Vital Tooth Bleaching Using Light Units—A Randomized Clinical Study

2013 ◽  
Vol 38 (1) ◽  
pp. 21-32 ◽  
Author(s):  
O Polydorou ◽  
M Wirsching ◽  
M Wokewitz ◽  
P Hahn
Keyword(s):  
Hydrogen Peroxide ◽  
Clinical Study ◽  
Chemical Activation ◽  
Color Stability ◽  
The Other ◽  
Tooth Bleaching ◽  
Bleaching Process ◽  
Randomized Clinical Study ◽  
Significant Difference

SUMMARY The aim of this study was to evaluate the color stability of vital bleaching using a halogen unit, laser, or only chemical activation up to three months after treatment. A total of 60 patients were divided into three groups, and their teeth were bleached with 38% hydrogen peroxide using three methods: acceleration of the bleaching process with halogen (eight minutes), laser (30 seconds), or chemical activation only. All teeth were bleached a maximum of four times (4 × 15 minutes) until a change of six shade tabs took place. The color was evaluated both visually and with a spectrophotometer before bleaching, immediately after bleaching, and one and three months after bleaching. Directly after bleaching, the use of halogen showed better results than laser (p≤0.05). One and three months after bleaching, no significant difference was found between the tested methods relative to the shade change, independent of the method of shade evaluation (p>0.05). As far as the color stability is concerned, bleaching with halogen resulted in stable color throughout the three months (p>0.05), whereas the other two methods resulted in whiter teeth after one and three months compared with the color directly after bleaching (p≤0.05). Bleaching with laser needed more time than halogen for the desired shade change (p≤0.05). Although directly after treatment bleaching with halogen resulted in better results, one and three months after bleaching the kind of acceleration used in the bleaching process did not have any effect on the esthetic results.

scholarly journals A Clinical Study Comparing the Efficacy and Sensitivity of Home vs Combined Whitening

2011 ◽  
Vol 36 (5) ◽  
pp. 460-466 ◽  
Author(s):  
PFL Dawson ◽  
MO Sharif ◽  
AB Smith ◽  
PA Brunton
Keyword(s):  
Hydrogen Peroxide ◽  
Clinical Study ◽  
Color Change ◽  
Carbamide Peroxide ◽  
Anterior Teeth ◽  
Randomized Clinical Study ◽  
Custom Made ◽  
Significant Difference ◽  
Group A ◽  
Change In Mean

SUMMARY This randomized clinical study assessed efficacy in terms of color change and production of sensitivity after home whitening alone and home whitening supplemented with in-office bleaching. Thirty-six subjects (aged 19 to 58 years) were randomly assigned to one of three different treatment groups: (A) home whitening for two weeks, with 16% carbamide peroxide in custom-made trays; (B) home whitening for two weeks, with 16% carbamide peroxide in custom-made trays supplemented with in-office bleaching with 9% hydrogen peroxide (in the same trays); or (C) home whitening for two weeks, with 16% carbamide peroxide in custom-made trays supplemented with in-office bleaching with 27% hydrogen peroxide (in the same trays). The efficacy of tooth whitening was assessed by determining the color change associated with the six upper anterior teeth using a value-ordered shade guide. Sensitivity was self-assessed with the use of a visual analog scale (VAS). Tooth shade and sensitivity were assessed at the following points: pretreatment; immediately after the home whitening phase; immediately after the in-office phase (groups B and C); and one week post active treatment. At the one week follow-up visit, subjects in group A had a mean (SD) color change of 5.9 (1.83) (teeth were lighter) immediately after cessation of treatment (p<0.01). Subjects in groups B and C experienced a greater change in mean (SD) shade immediately following their respective in-office treatments of 5.1 (1.53) and 5.4 (1.55). However, within one week, the shade of these teeth regressed to a similar degree to that achieved by subjects treated in group A. Overall, no significant difference in shade change or sensitivity was produced between the three groups. Investigators concluded that the in-office element of combined whitening produced no significant difference in tooth color or sensitivity when compared with home whitening alone.

Pengaruh Luka Iris Pada Tikus Dengan Paparan Hidrogen Peroxida 3% terhadap Epitelisasi dan Pembentukan Eksudat pada Permukaan Epitel Kulit.

2020 ◽  
Vol 17 (2) ◽  
pp. 172
Author(s):  
HARMAN AGUSAPUTRA ◽  
MARIA SUGENG ◽  
AYLY SOEKAMTO ◽  
ATIK WULANDARI
Keyword(s):  
Hydrogen Peroxide ◽  
Wound Healing ◽  
The Other ◽  
Delayed Wound Healing ◽  
Peroxide Group ◽  
Hemostatic Effect ◽  
Significant Difference ◽  
Negative Effect ◽  
Wound Healing Effect ◽  
Epithelial Growth

<p><strong>Abstract</strong></p><p><strong>Background:</strong> Hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) as antiseptic has been used frequently to clean woundsin in hospitals and clinics. Hydrogen peroxide has the effectof strong oxidative that can kill pathogens. It can clean up debris and necrotic tissuesin wounds. Hydrogen peroxidealso has hemostatic effect that can help to stop bleeding. Besides antiseptic effects, hydrogen peroxide i s suspected of having negative effect in wound healing. Hydrogen peroxide presumably could cause delayed wound healing by exudate formation and delayed epithelial growth.</p><p><strong>Method</strong>: This study was conducted in the laboratory using 48 white mice that were divided into 2 groups. All the mice were purposely wounded. Afterwards in one group the wounds were clean up using hydrogen peroxide, while in the other group without hydrogen peroxide as control. The wounds of both groups were observed on day 1, day 3 and day 7. On day 1 and day 3, both groups did not show significant difference.</p><p><strong>R</strong><strong>esult</strong> : on day 7 showed that the wound healing in hydrogen peroxide group were delayed. Fifty percent of them had the formation of exudate and 62.5% of them showed delayed epithelial growth.</p><p><strong>Conclusion </strong>: This study could show hydrogen peroxide as wound antiseptic has delayed wound healing effect.</p><p><strong>Keyword</strong>: hydrogen peroxide, wound healing</p>

Effect of administration rate on propofol requirement in cats

2017 ◽  
Vol 20 (2) ◽  
pp. 91-94 ◽  
Author(s):  
Renato LS Oliveira ◽  
Clarissa MR Moreira ◽  
Myla CB Barcellos ◽  
Camile PP Silva ◽  
Jorge GC Teixeira ◽  
...  
Keyword(s):  
Clinical Study ◽  
The Other ◽  
Analog Scale ◽  
Anesthetic Induction ◽  
Significant Difference ◽  
Sedation Scores ◽  
Adequate Sedation ◽  
Descriptive Scale ◽  
To Receive ◽  
Administration Rate

Objectives The objective of this study was to determine the effect of administration rate on propofol dose for induction of anesthesia and the effect of methadone on this dose. Methods This was a prospective, randomized, blinded clinical study. Forty male cats (mean ± SD age 1.5 ± 0.8 years) were admitted for orchiectomy. Cats were randomly allocated to receive acepromazine (0.05 mg/kg) with either methadone (MET; 0.3 mg/kg) or saline (SAL; 0.03 ml/kg). Each premedication group then received anesthetic induction with propofol at 5 (F) or 1.5 mg/kg/min (S), resulting in the following four groups: MET-F, SAL-F, MET-S and SAL-S. Sedation scores were assigned at 15 and 30 mins after premedication using a simple descriptive scale (SDS) and a visual analog scale (VAS). After assignment of sedation scores, respiratory frequency ( fR) was recorded, and anesthetic induction began and was continued until cats lost their palpebral reflexes and jaw tone, and the eye globe rotated ventromedially. The time for induction and the total amount of propofol needed was recorded, and intubation was then performed. After intubation, fR was also recorded. Results SDS and VAS sedation scores were low at 15 and 30 mins after premedication. There was no significant difference in sedation scores by time or between the groups at any time on any scale. The amount of propofol needed to achieve anesthetic induction was 5.3 ± 1.1 mg/kg in group MET-F, which was statistically lower when compared with the other three groups, which demonstrated no difference among them. Conclusions and relevance Premedication with acepromazine and methadone was not able to produce adequate sedation in healthy cats. The slow induction rate is not adequate for use in cats considering that all of the animals demonstrated excitement during anesthetic induction. The fast administration rate was able to produce adequate induction of anesthesia and reduce the amount of propofol needed to achieve intubation only when using methadone.

scholarly journals Evaluation of Physiological Intracranial Calcifications in Children Using Computed Tomography

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Katarina Raspopovic ◽  
Valentina Opancina ◽  
Maja Vulovic ◽  
Slavica Markovic ◽  
Radisa Vojinovic
Keyword(s):  
Computed Tomography ◽  
Clinical Study ◽  
Pineal Gland ◽  
The Other ◽  
Intracranial Calcifications ◽  
Randomized Clinical Study ◽  
Clinical Center ◽  
The Subject ◽  
The Mean ◽  
Neuro Imaging

AbstractIntroduction. Physiological intracranial calcifications have an increasing prevalence with the age and can be found in both children and in adults. These calcifications are basically asymptomatic and their presence can only be noticed through neuro-imaging.The aim of the paper was to evaluate physiological intracranial calcifications in children using computed tomography, in our conditions.Materials and methods. The study was designed as a retrospective, observational, non-randomized clinical study. It was conducted at the Department of Radiology, Clinical Center Kragujevac, Serbia. The study included all the patients scanned by CT from 1st October, 2008. to 30th September, 2018.. The criteria for the inclusion were: the patients aged up to 18 years who underwent a non-contrast computed tomography in the observed period, with diagnosed intracranial calcifications that do not have pathological etiology.Results. Our study included 420 patients. Out of them, 213 (50.7%) were boys and 207 (49.3%) were girls. The mean age was 12.47. We divided the patients into two age categories: the first one included the patients aged 1 to 10 years and the other one included the patients aged 11 to 18 years. Our study has demonstrated that physiological intracranial calcifications are the most frequent in habenula (28.1%), followed by the pineal gland (22.6%) and choroid plexus (18.8%).Conclusion. There is a small number of studies with the subject of physiological intracranial calcification distribution, especially in children. It is important to know in which locations we can expect physiological intracranial calcifications, as well as the age in which they become detectable by imaging, in order not to mix them with hemorrhages, pathological tumor or metabolic mineralization.

scholarly journals A COMPARATIVE CLINICAL STUDY TO EVALUATE THE EFFICACY OF DARVYADI LEHYA AND DRAKSHADI LEHYA IN PANDU ROGA W.S.R TO I.D.A

2020 ◽  
Vol 8 (9) ◽  
pp. 4324-4328
Author(s):  
Karthika Raj ◽  
Susheel Shetty
Keyword(s):  
Clinical Practice ◽  
Clinical Study ◽  
Data Base ◽  
Clinical Features ◽  
The Other ◽  
Significant Difference ◽  
The World ◽  
Before And After ◽  
Comparative Clinical Study ◽  
Global Data

Pandu is a Pitta Pradhana Tridoshaja Vikara affecting the Rasavaha srotas causing Sapta Dhatu Kshaya and Ojokshaya1. The disease is characterized by Panduvamata and Arohana Ayasa. Karnakshweda, Agnimandya, Daurbalya, Annadwesha, Srama, Bhrama, Gathrashoola, Arohanaayasa, Aruchi, Gaurava etc. are the other symptoms commonly found in the patients of Pandu. In the Present era, Anaemia is a burning issue around the world and W.H.O Global data base 2011 reveals that, in a 120 million population, 83% people are suffering from anaemia2.Present study was conducted on 60 diagnosed patients of Panduwho were randomly allocated with 30 each in two groups. Darvyadhi Lehya was given for one group and Drakshadhi Lehya a widely used formulation in clinical practice was given for another group. The study was conducted in 60 subjects for a period of 30 days. Clinical features and haematological parameters were documented before and after the treatment. The results of the study showed that, a statistically significant difference was not seen between the effect of Darvyadi and Drakshadilehya in Pandu roga.

scholarly journals The Effect of Nebulized Magnesium Sulphate on the Incidence of Postoperative Sorethroat

2020 ◽  
Vol 5 (1) ◽  
pp. 185-190
Author(s):  
T. Padma ◽  
Raju B ◽  
Raviraj GS
Keyword(s):  
Clinical Study ◽  
Sore Throat ◽  
Normal Saline ◽  
Magnesium Sulphate ◽  
Age Group ◽  
Postoperative Sore Throat ◽  
Medical College ◽  
Randomized Clinical Study ◽  
Significant Difference ◽  
Definition Of

Background: Postoperative sore throat (POST) is a well-recognized complication that remains unresolved in patients undergoing endotracheal intubation for general anaesthesia. The wide variation in these figures is presumably due to different skills and techniques among anesthetists and to differences between patients in the definition of sore throat. The main aim is to study the attenuating effect of Magnesium sulphate nebulization on the incidence of post-operative sore throat. Subjects and Methods: This is a prospective randomized clinical study. A total number of 100 patients of ASA grade 1 & 2, in the age group of 18 - 60 years. The study has been carried out at Sri Venkateswara Ram Narayana Ruia Government General Hospital, Sri Venkateswara Medical College, Tirupati, over a period of 12 months. Results: There was no significant difference among the groups in terms of age, gender and weight. Whereas Magnesium sulphate significantly lessens the POST during swallowing at 4th hour as compared to Normal saline (p< 0.05) and this statement can be attributed to any population. Conclusion:  Post-operative sore throat is one of the most common undesirable anesthesia-associated problems in the patients undergoing GA with an endotracheal tube for routine surgical cases for up to 24 h. Magnesium sulphate was significantly reduces the incidence of POST compared to Normal saline , and it is safe, simple and effective in reducing postoperative sore throat.

scholarly journals Clinical evaluation of domestic dental whitening strategies

2021 ◽  
Vol 10 (5) ◽  
pp. e35610514948
Author(s):  
João Victor Batista Soares Silva ◽  
Vitória Alves de Melo ◽  
Marlon Ferreira Dias ◽  
Paulo Cardoso Lins-Filho ◽  
Fábio Barbosa de Souza ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Tooth Bleaching ◽  
Control Group ◽  
Night Time ◽  
Tooth Sensitivity ◽  
Home Based ◽  
Chemically Induced ◽  
Significant Difference ◽  
Degree Of Satisfaction ◽  
Gingival Irritation

Tooth bleaching has become the first clinical option in reversing chromatic changes. This study evaluated the efficiency of four different approaches for home-based chemically induced tooth whitening. 32 patients were randomly distributed into four groups (n=8), according to the bleaching technique performed: G1: control group – at-home dental bleaching with 10% carbamide peroxide (Whiteness Perfect/FGM) delivered in a customized tray, G2: teeth whitening pen containing hydrogen peroxide (Walgreens), G3: night-time whitening gel (CVS) containing hydrogen peroxide and G4: whitening strips (3D White Oral B) containing 10% hydrogen peroxide. Chromatic changes (ΔE) were collected at baseline and at the middle and end of the treatment, using a digital spectrophotometer (EasyShade – Vita). Tooth sensitivity, gingival irritation, and degree of satisfaction were also recorded. The comparison between the average ΔE means, considering the final and initial values, revealed a statistically significant difference between the results obtained by G1 (ΔE2=11.65) and the other groups (ΔE2 of G2=4.38, G3=4.83 and G4 = 8.32). No significant difference was observed in the occurrence of tooth sensitivity and gingival irritation. The patients from G1 and G4 were more satisfied with the treatment outcome.

scholarly journals Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment

2018 ◽  
Vol 15 (5) ◽  
pp. 482-492 ◽  
Author(s):  
Kiyomi Nishimaki ◽  
Takashi Asada ◽  
Ikuroh Ohsawa ◽  
Etsuko Nakajima ◽  
Chiaki Ikejima ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Clinical Study ◽  
Molecular Hydrogen ◽  
Word Recall ◽  
Control Group ◽  
Stress Model ◽  
Randomized Clinical Study ◽  
Significant Difference

Background: Oxidative stress is one of the causative factors in the pathogenesis of neurodegenerative diseases including mild cognitive impairment (MCI) and dementia. We previously reported that molecular hydrogen (H2) acts as a therapeutic and preventive antioxidant. Objective: We assess the effects of drinking H2-water (water infused with H2) on oxidative stress model mice and subjects with MCI. Methods: Transgenic mice expressing a dominant-negative form of aldehyde dehydrogenase 2 were used as a dementia model. The mice with enhanced oxidative stress were allowed to drink H2-water. For a randomized double-blind placebo-controlled clinical study, 73 subjects with MCI drank ~300 mL of H2-water (H2-group) or placebo water (control group) per day, and the Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-cog) scores were determined after 1 year. Results: In mice, drinking H2-water decreased oxidative stress markers and suppressed the decline of memory impairment and neurodegeneration. Moreover, the mean lifespan in the H2-water group was longer than that of the control group. In MCI subjects, although there was no significant difference between the H2- and control groups in ADAS-cog score after 1 year, carriers of the apolipoprotein E4 (APOE4) genotype in the H2-group were improved significantly on total ADAS-cog score and word recall task score (one of the sub-scores in the ADAS-cog score). Conclusion: H2-water may have a potential for suppressing dementia in an oxidative stress model and in the APOE4 carriers with MCI.

scholarly journals Improving shear bond strength of metallic brackets after whitening

2020 ◽  
Vol 25 (5) ◽  
pp. 38-43
Author(s):  
Juan Fernando Aristizábal ◽  
Angela Patricia Polanía González ◽  
James A. McNamara
Keyword(s):  
Hydrogen Peroxide ◽  
Bond Strength ◽  
Shear Bond Strength ◽  
Artificial Saliva ◽  
Tooth Bleaching ◽  
Sodium Ascorbate ◽  
Control Group ◽  
Antioxidant Treatment ◽  
Significance Level ◽  
Significant Difference

ABSTRACT Objective: To evaluate a protocol for bonding metallic brackets after bleaching with hydrogen peroxide (HP). Methods: 60 extracted maxillary premolar were randomly divided into an unbleached control group and two groups bleached with a solution of 35% hydrogen peroxide prior to bonding. The teeth in one of the treated groups were bonded immediately after bleaching; while the other group was treated with 10% sodium ascorbate immediately after bleaching and before bonding. The teeth in all groups were stored in an artificial saliva solution for 7 days after bonding. The shear bond strength data was measured in megapascals (MPa) and the fail attempts were verified. The significance level was established at p< 0.05. Results: The unbleached group, in which brackets were bonded to untreated enamel, had the highest bond strength values (11.0 ± 5.7MPa) in comparison to the bleached group (7.14 ± 40MPa), in which brackets were bonded to recently bleached enamel. Slightly improved bond strength was observed in the antioxidant group (8.13 ± 5.4MPa), in which the teeth were bleached and then the antioxidant was applied to the teeth before bonding. Unbleached and bleached groups showed statistically significant difference for shear bond strength (p=0.03) and load strength (p=0.03); no significant differences were noted between unbleached and antioxidant groups (p=0.52). Conclusion: The antioxidant treatment applied immediately after bleaching was effective in reversing the reduction in shear bond strength of brackets after tooth bleaching.

scholarly journals Photobiomodulation vs. Placebo on Post-Bleaching Sensitivity and Color Change: A Split-Mouth Clinical Study

2020 ◽  
Vol 14 (1) ◽  
pp. 267-274
Author(s):  
Caroline C. de Silva ◽  
Cristiane de M. Alencar ◽  
Brennda L. F. de Paula ◽  
Fernanda F. de A. Jassé ◽  
Jesuína L. N. Araújo ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Color Change ◽  
Tooth Bleaching ◽  
Low Level Laser Therapy ◽  
Tooth Color ◽  
Pain Evaluation ◽  
Level Laser ◽  
Significant Difference ◽  
The Right ◽  
Post Hoc

Objective: This study aimed to investigate the efficiency of Photobiomodulation (PBM) with low-level LASER therapy compared to placebo in post-bleaching sensitivity and color change during a three-week office bleaching treatment. Methods: A split-mouth model was used to evaluate 21 subjects. The right and left hemi-archs were randomized to one of two groups: GP (placebo): simulated LASER application followed by tooth bleaching with 35% hydrogen peroxide; and GL: treated with PBM followed by tooth bleaching with 35% hydrogen peroxide. A four-degree modified Visual Analog Scale (VAS) was used to assess tooth sensitivity after the application of an evaporative stimulus (stimulated pain). In addition, a daily questionnaire was used to measure unstimulated pain. The color change was measured using a spectrophotometer. The Friedman and Wilcoxon tests were used to analyze data sensitivity. Color results were statistically analyzed using Analysis Of Variance (ANOVA) followed by the Tukey post-hoc test. Results: There was no significant difference between GP and GL for stimulated pain evaluation (p> 0.05). However, there was a significant difference between the groups for unstimulated pain evaluation (p≤ 0.05). In addition, ΔE data did not reveal any significant difference in tooth color between groups at any time (p> 0.05). Conclusion: PBM prevented post-bleaching sensitivity compared to placebo, based on the daily pain assessment questionnaires. PBM did not compromise the quality of bleaching treatments.

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