scholarly journals The effect of mineral supplements on resorption in the digestive tract of cattle, with special reference to Bolus alba

1966 ◽  
Vol 38 (1) ◽  
pp. 59-63
Author(s):  
K. Roine ◽  
T. Varvikko ◽  
L. Lappalainen ◽  
K. Östring

Fourteen sexually mature heads of cattle were divided into two groups; Group I receiving mineral mixture A, containing 15 % of Bolus alba, while Group II were given mixture B, containing no Bolus alba, but 10 % more Ca. Otherwise, both groups received the same feeding. Samples of blood and faeces of the animals were taken monthly for the determination of phosphorus, respectively phosphorus and carotenes. The experiment lasted one stabling period. In Group I, the mean inorganic phosphorus values of the blood were 6.7 mg/100 ml. and in Group 11, 6.1 mg/100 ml. The mean phosphorus values of the faeces were 8.8 gr/kg dry matter in Group I and in Group II, 9.3 gr/kg dry matter. The mean carotene values in Group I were 98.3 mg/kg dry matter and in Group II, 96.3 mg/kg dry matter. However, none of these differencies is statistically significant. On the basis of the present investigation it can be concluded that Bolus alba exerts no detrimental influence on the resorption of phosphorus and carotenes in the digestive tract of cattle.

1992 ◽  
Vol 76 (6) ◽  
pp. 1029-1031 ◽  
Author(s):  
Edward C. Benzel ◽  
Jay P. Mashburn ◽  
Steven Conrad ◽  
Denise Modling

✓ The absence of spontaneous respirations at a PaCO2 of 60 mm Hg or above has traditionally been accepted as the respiratory criteria for the determination of brain death. The testing of patients for the presence or absence of apnea has been complicated because the rate of PaCO2 elevation may vary substantially from patient to patient, and a nonlinear relationship exists between the rate of PaCO2 increase and the duration of apnea. In an attempt to refine the apnea test and to further elucidate the physiology of hypercapnia in humans, 11 patients who met all but the respiratory criteria for brain death were evaluated using a modification of a previously utilized apnea testing protocol. All patients were brought to a PaCO2 of 40 mm Hg or above prior to the apnea test. Baseline PaCO2 ranged from 40 to 45 mm Hg in six patients (Group I) and from 46 to 51 mm Hg in five patients (Group II). The mean rate of PaCO2 increase was 5.1 ± 1.4 mm Hg/min in Group I and 6.7 ± 3.1 mm Hg/min in Group II. No problems with cardiovascular instability or hypoxia were encountered during testing in this series. This refinement of the apnea test allows for a streamlined and safe approach to brain death detection.


1968 ◽  
Vol 70 (1) ◽  
pp. 87-94 ◽  
Author(s):  
J. N. Peart

SUMMARYData collected from mid-pregnancy until the 5th week of lactation were used to select three nearly uniform groups each of nine ewes suckling single lambs. After 4 weeks of lactation, experimental treatments were applied to these selected groups as follows: Group I. Both ewes and lambs fed ad lib.throughout. Group II. Ewes fed ad lib. throughout. Lambs offered one-third the quantity of solid food being consumed by group I lambs. Group III. Food intake of ewes restricted to 9·2 g D.o.M./kg, based on their mid-pregnancy live weights. Lambs fed ad lib. throughout. The effects of these treatments were assessed in terms of milk production, food intakes and live-weight changes of ewes, and the solid food intake and growth rates of lambs. Mean total milk production of ewes of groups I and II remained similar until the 8th lactation week, but during the 8–12 week period milk production of the ewes in group II was 6·17 kg greater than that of ewes in group I. The data suggest this difference was due to a reduced intake of milk by the lambs suckling the ewes in group I during the weaning process. From week 4 the milk yield of group III ewes declined rapidly and though these ewes drew on body reserves for milk production, this process could not sustain milk yields. The average daily live-weight gains of lambs of groups I and III were both significantly greater than that of group II, and the gain of group I lambs was significantly greater than that of group III. All groups of ewes made similar live-weight gains during early lactation and after 4 weeks each group had attained a mean value of about 60 kg. Groups I and II continued to gain weight and during week 12 their respective mean weights were 67 and 65 kg. This difference was not statistically significant. The mean live weight of group III ewes declined rapidly after week 4, reaching a minimum value of 41·5 kg. The mean daily intake of dry matter by ewes of all groups reached a maximum value of about 2·9 kg/ewe in lactation week 3 and declined to about 2·6 kg in week 4. Intakes by ewes in groups I and II were almost identical throughout. During the period of restricted feeding the mean daily intake of group III ewes was 0·58 kg dry matter/ewe. During week 5 the mean daily intakes of solid food dry matter by lambs of groups I, II and III were 44, 32 and 158 g respectively. These increased to 1230, 418 and 1537 g respectively during week 12.


2021 ◽  
Vol 62 (11) ◽  
pp. 1478-1482
Author(s):  
Mi Jeong Kim ◽  
Ji Seon An ◽  
Ja Yoon Moon ◽  
Hee Young Kim ◽  
Jin Seok Choi ◽  
...  

Purpose: To investigate the safety of laser epithelial keratomileusis (LASEK) by drawing a comparison between two groups divided according to age (18-19 vs. 20-21 years old).Methods: The study was conducted as a retrospective analysis including 339 patients (678 eyes) who underwent LASEK between January 2017 and April 2020. Patients were divided by age group, group I (18-19 years old) and group II (20-21 years old). The objectives of the study included determination of visual acuity and refractive errors before and at 1, 3, and 6 months after the procedure.Results: The preoperative mean spherical equivalents (SEs) were -4.73 ± 0.88 diopters (D) in group I and -4.58 ± 0.87 D in group II (p = 0.34). At 1 month postoperatively, mean SEs were 0.32 ± 0.46 D in group I and 0.26 ± 0.59 D in group II (p = 0.18). At 3 months postoperatively, the mean SEs were 0.30 ± 0.47 D in group I and 0.28 ± 0.50 D in group II (p = 0.67). At 6 months postoperatively, the mean SEs were 0.15 ± 0.47 D in group I and 0.14 ± 0.50 D in group II (p = 0.89). There were no significant differences in postoperative best corrected visual acuity between group I and group II at 1, 3, or 6 months (p = 0.20, p = 0.13, and p = 0.11, respectively).Conclusions: There were no significant differences in postoperative mean SE or safety of LASEK between moderate myopia patients 18-19 years old and those 20-21 years old.


2020 ◽  
Vol 16 (01) ◽  
pp. 01-06
Author(s):  
Mehrajuddin Naikoo ◽  
Arjun J Dhami ◽  
Bhupendra C Parmar

A study was conducted on 12 pluriparous parturient Kankrej cows of the University Farm, in Anand, randomly divided into two equal groups (n = 6 each). Group-I cows were administered on the day of calving with a sustained release 80 g mega mineral rumen bolus (Prepavel® 1 bolus/animal, Neolait, France) intra-ruminal through a specially designed applicator, while group-II animals served as untreated control. The animals were monitored periodically from the day of calving till 140 days postpartum along with other herd mates. Blood samples were obtained at 10 days interval in heparinized vacutainers for plasma progesterone, biochemical, and macro-micro mineral profiling. Among the six Kankrej cows of group-I, only one animal exhibited prominent estrus signs on day 96 postpartum and conceived at first service (AI) giving CR of 16.66%, while in group-II three cows exhibited estrus between day 73 and 86 postpartum, and conceived with one or two AI giving CR of 50% by 150 days postpartum. In both the groups, all other cows remained subestrus for more than 150 days postpartum and conceived very late, though mostly with single service at spontaneous estrus. The mean values of plasma progesterone (0.74 ± 0.32 to 5.57 ± 0.78 ng/mL), total cholesterol (103.88 ± 3.20 to 237.17 ± 24.66 mg/dL) and triglycerides (17.07 ± 1.16 to 28.29 ± 1.75 mg/dL) differed significantly (p less than 0.01) between postpartum intervals in both the groups, but not between groups at any of the intervals. The values of plasma total protein, calcium, inorganic phosphorus, and magnesium as well as trace elements, viz., zinc, iron, copper, cobalt, and manganese, however varied insignificantly and inconsistently between intervals and also between groups from day 0 to day 140 postpartum. Thus, the insertion of Mega mineral ruminal bolus on the day of calving did not influence the plasma profile of biochemical/ metabolic constituents and macro-micro minerals profile in lactating postpartum Kankrej cows and was not beneficial in improving postpartum fertility. However, further study on a larger sample size is required to draw a valid conclusion.


2012 ◽  
Vol 5 (1) ◽  
pp. 37-43
Author(s):  
ABMM Alam ◽  
M Moniruzzaman ◽  
MB Alam ◽  
N Islam ◽  
F Khatoon ◽  
...  

Background: CIN has gained increased attention in the clinical setting, particularly during cardiac intervention but also in many other radiological procedures in which iodinated contrast media are used. There is at present good clinical evidence from well-controlled randomized studies that CIN is a common cause of acute renal dysfunction.Methodology: This was a prospective study conducted among the patients who underwent coronary angiography and percutaneous coronary intervention in the Department of Cardiology, Dhaka Medical College Hospital during January 2010 to December 2010. A total of 111 patients age range from 25 to 75 years were included in the study. Serum creatinine level at baseline and at the end of 48 hours was done in all these patients. Study population was divided into two groups according to development of acute kidney injury (AKI). Group-I = AKI, Group II = Not developed AKI. Results: AKI developed 11.7% of the study patient. DM and Preexisting renal insufficiency were significantly higher in group I patients. HTN was (61.5% Vs 44.9%) higher in group I but not significantly. History of ACE inhibitor/ARB, NSAID intake and LVEF <40% were significantly higher in group I patients. The mean±SD volume of CM (Contrast Media) were 156.9±44.8 ml and 115.4±30.0 ml in group I and group II respectively, which was significant. The mean±SD of serum creatinine after 48-72 hours of CAG/PCI was 1.4±0.37 mg/dl and 1.1±0.2 mg/dl in group I and group II respectively. The serum creatinine level increased significantly (p<0.05) after 48-72 hours of CAG/PCI in group I. In group II, S. creatinine level increased but not significant (p>0.05). Impaired renal function was found 76.9% and 2.0% in group I and group II respectively. DM, HTN, preexisting renal insufficiency, ACE inhibitor/ARB, NSAIDs, contrast volume (>150 ml), eGFR (<60 ml/min/ 1.73m2) and LVEF (<40%) are significantly (p0.05) associated for CIN development.Conclusion: CIN is an iatrogenic but preventable disorder results from the administration of contract media. Although rare in the general population, CIN occurs frequently in patients with underlying renal dysfunction and diabetes. In patients with pre angiographic normal renal function, the prevalence is low but in pre-existing renal impairment it may pose a serious threat. Thus risk factors are synergistic in their ability to predispose to the development of CIN. A careful risk-benefit analysis must always be performed prior to the administration of contrast media to patients at risk for CIN. DOI: http://dx.doi.org/10.3329/cardio.v5i1.12227 Cardiovasc. j. 2012; 5(1): 37-43


Genetics ◽  
1996 ◽  
Vol 142 (1) ◽  
pp. 295-303 ◽  
Author(s):  
Jianzhi Zhang ◽  
Masatoshi Nei

Antennapedia (Antp)-class homeobox genes are involved in the determination of pattern formation along the anterior-posterior axis of the animal embryo. A phylogenetic analysis of Antp-class homeodomains of the nematode, Drosophila, amphioxus, mouse, and human indicates that the 13 cognate group genes of this gene family can be divided into two major groups, i.e., groups I and II. Group I genes can further be divided into subgroups A (cognate groups 1–2), B (cognate group 3), and C (cognate groups 4–8), and group II genes can be divided into subgroups D (cognate groups 9–10) and E (cognate groups 11–13), though this classification is somewhat ambiguous. Evolutionary distances among different amino acid sequences suggest that the divergence between group I and group II genes occurred ∼1000 million years (MY) ago, and the five different subgroups were formed by ∼600 MY ago, probably before the divergence of Pseudocoelomates (e.g., nematodes) and Coelomates (e.g., insects and chordates). Our results show that the genes that are phylogenetically close are also closely located in the chromosome, suggesting that the colinearity between the gene expression and gene arrangement was generated by successive tandem gene duplications and that the gene arrangement has been maintained by some sort of selection.


2019 ◽  
Vol 2 (3) ◽  
pp. 137-141
Author(s):  
Padma Raj Dhungana ◽  
Rajesh Adhikari ◽  
Prem Raj Pageni ◽  
Apsara Koirala ◽  
Anand Nepal

Background: Labor is a naturally occurring physiological process associated with uterine contractions, effacement, dilatation of cervix and descent of presenting part. Drotaverine hydrochloride is a non-anticholinergic isoquinoline derivative which acts by elevating intracellular cyclic Adenosine Mono Phosphate (cAMP) and cyclic Guanosine Mono Phosphate (cGMP) promoting smooth muscle relaxation. Materials and Method: This was a hospital based prospective study on effectiveness of Drotaverine Hydrochloride on enhancing dilatation of cervix and acceleration of active phase of labor. The sample size was 100. Fifty cases of women in active phase of labor received injection drotaverine hydrochloride 40 mg (group i) and fifty cases of women did not receive any drug (group ii) among those at term with singleton pregnancy and vertex presentation. Variables like maternal age, interval between administration of drug and delivery, mode of delivery, apgar score at 5 minutes, NCU (Neonatal Care Unit) admission and neonatal outcomes were recorded. Data analysis was done with the help of SPSS program. Results: The mean interval between drug administration to delivery in primipara and multipara in group i was 3.05 hours and 2.31 hours while in group ii was 4.5 hours and 3.75 hours respectively. The mean interval between drug administration and delivery was shorter in both groups of multipara. In group i, 96% had normal delivery and 4 % had vacuum delivery and in group ii 90% and 10% had normal delivery and vacuum delivery respectively. None of the participants had caeserian section. There were no perinatal mortalities. Conclusion: The administration of drug Drotaverine Hydrochloride is effective in shortening duration of labor with favorable feto-maternal outcome.  


2010 ◽  
Vol 12 (5) ◽  
pp. 525-532 ◽  
Author(s):  
Kyeong Hwan Kim ◽  
Sang-Ho Lee ◽  
Dong Yeob Lee ◽  
Chan Shik Shim ◽  
Dae Hyeon Maeng

Object The purpose of the present study was to evaluate the efficacy of anterior polymethylmethacrylate (PMMA) cement augmentation in instrumented anterior lumbar interbody fusion (ALIF) for patients with osteoporosis. Methods Sixty-two patients with osteoporosis who had undergone single-level instrumented ALIF for spondylolisthesis and were followed for more than 2 years were included in the study. The patients were divided into 2 groups: instrumented ALIF alone (Group I) and instrumented ALIF with anterior PMMA augmentation (Group II). Sixty-one patients were interviewed to evaluate the clinical results, and plain radiographs and 3D CT scans were obtained at the last follow-up in 46 patients. Results The mean degree of cage subsidence was significantly higher in Group I (19.6%) than in Group II (5.2%) (p = 0.001). The mean decrease of vertebral body height at the index level was also significantly higher in Group I (10.7%) than in Group II (3.9%) (p = 0.001). No significant intergroup differences were observed in the incidence of radiographic adjacent-segment degeneration (ASD) or in terms of pain and functional improvement. The incidences of clinical ASD (23% in Group I and 10% in Group II) were not significantly different. There was 1 case of nonunion and 3 cases of screw migration in Group I, but none resulted in implant failure. Conclusions Anterior PMMA augmentation during instrumented ALIF in patients with osteoporosis was useful to prevent cage subsidence and vertebral body collapse. In addition, PMMA augmentation did not increase the nonunion rate and incidence of ASD.


2004 ◽  
Vol 23 (8) ◽  
pp. 413-419 ◽  
Author(s):  
Cetin Kaymak ◽  
Ela Kadioglu ◽  
Hulya Basar ◽  
Semra Sardas

In this study, genotoxic effects of repeated sevoflurane anaesthesia were investigated in rabbits with or without antioxidant supplementation. Twenty-one New Zealand male rabbits were included in the study and randomized into three groups as: placebo treated (Group I), vitamin E supplemented (Group II) and selenium supplemented (Group III). Vitamin E and selenium were given intraperitoneally for 15 days before anaesthesia treatment. Anaesthesia was administered using 3% sevoflurane in 4 L/min oxygen for a 3-hour period and continued for 3 days. Blood samples were collected before anaesthesia (Sample 1), after the first, second and third days of sevoflurane administration (Sample 2, Sample 3 and Sample 4 respectively) and the last samples were taken 5 days after the last sevoflurane administration (Sample 5). Genotoxic damage was examined using the comet assay. The degree of damage is assessed by grading the cells into three categories of no migration (NM), low migration (LM) and high migration (HM) depending on the fraction of DNA pulled out into the tail under the influence of the electric field. The number of comets in each sample was calculated (1 × number of comets in category NM + 2 × number of comets in category LM + 3 ×number of comets in category HM) and expressed as the total comet score (TCS), which summarizes the damage frequencies. In Group I, a significant increase in the mean TCSs was observed for Samples 3 and 4 as compared with Sample 1. However, there were no significant differences between Samples 1, 2 and 5. The mean TCS of Sample 4 was significantly higher than Sample 1, 2 and 3 in Group II. Group III demonstrated no significant mean TCSs for any experimental conditions. Statistical differences were also observed between the groups with significant P values. This experimental study points out the presence of DNA damage with repeated sevoflurane anaesthesia and the genoprotective role of antioxidant supplementation on DNA damage in mononuclear leukocytes of rabbits by highly sensitive comet assay.


1998 ◽  
Vol 39 (5) ◽  
pp. 538-542 ◽  
Author(s):  
R. Andresen ◽  
S. Radmer ◽  
D. Banzer

Objective: the clinical value of spinal quantitative CT (sQCT) and the structural patterns of the vertebral bone were studied Material and Methods: sQCT was performed on 246 patients with a mean age of 57 years for whom conventional lateral radiographies of the thoracic and lumbar spine were available. All patients were suffering from back pain of unknown etiology. the bone mineral density (BMD) of the midvertebral section of 3 lumbar vertebral bodies was determined by means of single-energy-(SE)-weighted QCT (85 kV). Spongiosa architecture and density profile analyses were made in the axial images. This was contrasted to BMD values ascertained in SE QCT. the mean BMD was compared to the number of fractures and the patients were divided into three groups: group I — no fracture; group II — one fracture; and group III 1 fracture Results: the mean BMD was: 134.3 (74.1–187.5) mg hydroxyapatite (HA)/ml in group I; 79.6 (58.6–114.3) mg HA/ml in group II; and 52.4 (13.1–79.1)mg HA/ml in group III. A significant deterioration in spongiosa structure was found with increasing demineralization: strongly rarefied patterns predominated in the fracture groups II and III Conclusion: sQCT provides a good risk assessment of the occurrence of vertebral body insufficiency fractures


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