scholarly journals Effect of Xanthohumol Added to Diet on Blood Biochemistry in Japanese Quails

2021 ◽  
Vol 9 (6) ◽  
Author(s):  
Zuzana Lacková ◽  
František Zigo ◽  
Zuzana Farkašová
Keyword(s):  
Enzyme Activity ◽  
Total Protein ◽  
Aspartate Aminotransferase ◽  
Alanine Aminotransferase ◽  
Biochemical Parameters ◽  
Blood Biochemistry ◽  
Control Group ◽  
Japanese Quails ◽  
Experimental Group ◽  
Alt Alanine Aminotransferase

In this paper, we monitored to effect of xanthohumol added to diet on blood biochemistry in Japanese quails. Forty Japanese quails breeds lines Pharaoh were included in the experiment. The quails were randomly divided into two groups: one control and one experimental group with supplementation by xanthohumol in feed. In the evaluation of biochemical parameters, we focused on total protein, albumin, globulin, glucose, cholesterol and enzyme activity of AST (Aspartate aminotransferase), ALT (Alanine aminotransferase) and ɤ-GT (ɤ-Glutamyltransferase). Statistical comparisons were made between group with supplementation by xanthohumol in feed and the control group. Total protein and albumin levels were significantly differed between groups (P <0.05). A significant decrease in AST activity (P <0.05) was observed in supplementation group relative to control group.

scholarly journals Protein-synthesizing function and functional state of the liver of dogs at experimental toxocariasis

2020 ◽  
Vol 22 (98) ◽  
pp. 132-137
Author(s):  
W. S. Said ◽  
V. V. Stybel ◽  
B. V. Gutyj ◽  
O. B. Pryima ◽  
I. Y. Mazur
Keyword(s):  
Body Weight ◽  
Functional State ◽  
Total Protein ◽  
Aspartate Aminotransferase ◽  
Alanine Aminotransferase ◽  
Experimental Studies ◽  
Control Group ◽  
Activity Of Enzymes ◽  
Experimental Group

The aim of the study was to investigate the effect of toxocariasis invasion on protein-synthesizing function and functional state of the liver of dogs. For experimental studies, 12 dogs aged from two to four months were used and two groups of six animals were formed in each: control and experimental. Puppies of the experimental group were experimentally infected with the pathogen toxocariasis at a dose of 5,000 invasive eggs of T. canis per kg of body weight. The control puppies were clinically healthy. Protein-synthesizing function of the liver of dogs in experimental toxocariasis was studied by the level of total protein and its fractions. It was found that on the 25th day of the experiment the level of total protein in the blood of the experimental group of dogs was 56.9 ± 1.47 g/l, while in the control group – 63.8 ± 2.92 g/l. The lowest level of the studied indicator was on the 30th day of the experiment in the blood of the experimental group of dogs, where it decreased by 9.6 %. The results of a study of protein fractions in the blood of dogs infested with toxocara showed that the percentage of albumin is likely to decrease. However, in the blood of infected dogs in this period of research there was a probable increase in globulin levels. The study of the effect of toxocariasis invasion on the activity of enzymes in blood serum is a test for the morphological and functional state of tissues and organs. Based on the studies, it was found that with the development of toxocariasis invasion in dogs there is an increase in alanine aminotransferase in their serum. On the 25th and 30th day of the experiment, the activity of the enzyme in the serum of infected dogs was the highest, where compared with the control group of dogs, the activity of ALT increased by 51.2 and 59.1 %, respectively. Similar changes in activity were observed in the determination of aspartate aminotransferase, where, respectively, on the 15th, 20th and 25th day of the experiment, the activity of AST in the serum of infected dogs increased by 19.3, 27.5 and 39.1 %.

scholarly journals Occupational effect of spray painting fumes on some biochemical parameters in automobile spray painters in Yenagoa Bayelsa State, Nigeria

2021 ◽  
Vol 9 (2) ◽  
pp. 038-044
Author(s):  
Emmanuel Tonbra Egoro ◽  
Emmanuel Sunday Oni ◽  
Jonathan Ebipade Lawrence
Keyword(s):  
Aspartate Aminotransferase ◽  
Alanine Aminotransferase ◽  
Biochemical Parameters ◽  
Control Group ◽  
Chemical Toxicity ◽  
C Reactive Protein ◽  
Spray Painting ◽  
Plasma Urea ◽  
Reactive Protein ◽  
Experimental Group

Automobile spray painters are often prone to chemical toxicity due to their routine work. This study was aimed at the occupational effect of spray painting fumes on some biochemical parameters in automobile spray painters. Five milliliters of blood specimen were collected into lithium heparin anti-coagulated bottles from twenty five automobile spray painters with ≤ 10 years working experience (experimental group one), ≥ 11 years working experience (experimental group two) and non-automobile spray painters which were monitored as control group respectively. After this, plasma alanine aminotransferase, aspartate aminotransferase, C-reactive protein, urea and creatinine were measured quantitatively using a spectrophotometer. The mean values of all the measured biochemical parameters showed no statistically significant differences (p>0.05) in the automobile spray painters with ≤ 10 years working experience as compared with that of the control group with the exception of plasma C-reactive protein, while those with ≥ 11 years working experience showed statistically significant differences (p<0.05) in plasma alanine aminotransferase, aspartate aminotransferase and C-reactive protein however, the plasma urea and creatinine showed no statistically significant differences (p>0.05). In conclusion, the concentration of plasma alanine aminotransferase, aspartate aminotransferase and C-reactive protein may be altered in automobile spray painters with ≥ 11 years working experience, thus these biochemical parameters should be monitored regularly in spray painters within this category of working experience

scholarly journals Assessment of selected biochemical parameters among food hawkers along the streets of Yenagoa Bayelsa State, Nigeria

2021 ◽  
Vol 16 (3) ◽  
pp. 103-108
Author(s):  
Emmanuel Tonbra Egoro ◽  
Emmanuel Sunday Oni ◽  
Otaraku Jonathan Oye ◽  
Annabel Awele Idama
Keyword(s):  
Aspartate Aminotransferase ◽  
Alanine Aminotransferase ◽  
Biochemical Parameters ◽  
Control Group ◽  
C Reactive Protein ◽  
Mean Values ◽  
Reactive Protein ◽  
Significant Difference ◽  
The Mean ◽  
Experimental Group

This study was aimed on assessment of selected biochemical parameters among food hawkers along the streets of Yenagoa, Bayelsa State, Nigeria. Five milliliter of blood specimen was collected from fifteen food hawkers with ≤ 5 years working experience (experimental group one), ≥ 5 years working experience (experimental group two) and nonfood hawkers (control group) respectively into lithium heparin anti-coagulated bottles. Thereafter alanine aminotransferase, aspartate aminotransferase, urea, creatinine and C-reactive protein were measured quantitatively. The mean values of volunteers in experimental group one showed no statistically significant difference (p>0.05) in alanine aminotransferase (7.46 ± 1.02), aspartate aminotransferase (7.02 ± 0.86), urea (7.70 ± 1.29) and creatinine (70.44 ± 3.54) as compared with the control group (7.42 ± 0.98), (6.98 ± 0.82), (7.65 ± 1.28) and (70.40 ± 3.52) respectively, but there was a statistically significant difference (p<0.05) in C-reactive protein (17.40 ± 1.98) when compared with the control group (2.70 ± 0.70). However, the mean values of food hawkers in experimental group two showed statistically significant difference (p< 0.05) in all the measured biochemical parameters 27.70±2.98, 21.40±2.06, 15.50±2.02, 110.70±3.74, 29.42±3.20 as compared with that of the control group 7.42±0.98, 6.98±0.82, 7.65±1.28, 70.40±3.52, 2.74±0.70. The volunteers in experimental groups one and two showed 13% -27% and 53% -80% abnormal values of the measured biochemical parameters respectively as compared with that of the control group. In conclusion, alanine aminotransferase, aspartate aminotransferase, urea, creatinine and C-reactive protein may be altered in food hawkers with ≥ 5 years working experience. It is therefore recommended that food hawkers in this category should go for hepato-renal and inflammatory biochemical parameters checkup occasionally in any registered and licensed Medical Laboratory Facility.

scholarly journals Studies on some Biochemical Parameters among Charcoal (Physiculus nematopus) Traders in Swali Market Yenagoa Bayelsa State

2021 ◽  
Vol 6 (3) ◽  
pp. 74-80
Author(s):  
E.T. Egoro ◽  
E.S. Oni ◽  
J.O. Otaraku ◽  
D.E. John
Keyword(s):  
Aspartate Aminotransferase ◽  
Alanine Aminotransferase ◽  
Biochemical Parameters ◽  
Medical Laboratory ◽  
Control Group ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Laboratory Facility ◽  
Blood Specimens ◽  
Experimental Group

The aim of this study was to assess some biochemical parameters among charcoal (Physiculus nematopus) traders in Swali market Yenagoa Bayelsa State, Nigeria. Five milliliter of blood specimens was collected from each of the fifteen charcoal (Physiculus nematopus) traders with < 5 years working experience (experimental group one), fifteen charcoal (Physiculus nematopus) traders with ≥5 years working experience (experimental group two) and fifteen non charcoal traders (control group) into lithium heparin anti-coagulated bottles respectively. Thereafter alanine aminotransferase (ALT), aspartate aminotransferase (AST), urea, creatinine and C-reactive protein (CRP) were measured quantitatively. The results of charcoal traders in experimental group one showed no statistically significant differences (p>0.05) in all the measured biochemical parameters ALT (7.26U/I), AST (5.61U/I), CRP (2.48mg/L), urea (8.68mmol/L), creatinine (82.14µmol/L) as compared to that of the control group (7.22U/I), (5.58U/I), (2.47mg/L), (8.65mmo/L), (82.10µmol/L) respectively while that of experimental group two showed statistically significant differences (p<0.05) in alanine aminotransferase (20.40U/I), aspartate aminotransferase (16.20U/I) and C-reactive protein (22.42mg/L) as compared to that of the control group (7.22U/I), (5.58U/I), (2.47mg/L) respectively. However, urea (8.68mmol/L) and creatinine (82.25µmol/L) showed no statistically significant differences (p>0.05) as compared to that of the control group (8.65mmol/L), (82.10µmol/L) respectively. In conclusion alanine aminotransferase, aspartate aminotransferase and C-reactive protein may be altered in charcoal (Physiculus nematopus) traders exposed to charcoal dust for ≥ 5 years. It is therefore recommended that charcoal traders in this category should embark on hepato-inflammatory biochemical parameters investigation intermittently in any registered and licensed Medical Laboratory facility so as to monitor the concentrations of these parameters.

scholarly journals The effect of herbal phytoextract on metabolic parameters of sows and piglets

2021 ◽  
Vol 22 (3) ◽  
pp. 428-435
Author(s):  
A. A. Ivanovsky ◽  
N. A. Latushkina ◽  
E. Yu. Timkina
Keyword(s):  
Total Protein ◽  
Biochemical Parameters ◽  
Control Group ◽  
Total Protein Content ◽  
Herbal Extracts ◽  
Control Groups ◽  
Normal Range ◽  
Experimental Group ◽  
Experimental Pigs

The purpose of the research was to study the effect of a phytocomplex containing herbal extracts of R. carthamoides, S. coronata, F. ulmaria on blood biochemistry of milking sows, the development and viability of piglets born by the time of weaning. For the experiment, the animals were divided into an experimental (Phytoadditive) and a control (SPK-2 compound feed) groups, 10 animals each. Phytoadditive in dry form was introduced into the diet of pigs of the experimental group during the sucking period (30 days) daily, once per head per day - 10 grams (individually). Before the beginning and at the end of the experiment, the blood of sows was examined for biochemical parameters. The multiplicity, the quality of the piglets born, the weight of the nest and one pig after birth and before weaning, as well as viability were determined. As the result, it was found that the concentration of the investigated extractives in the Phytoadditive was 13.5 g/kg, of which 10.5 g were ecdysteroids and 3.0 g of flavonoid rutin. Significant changes in the total protein content in the blood compared with the beginning of the experiment were noted in experimental pigs from 60.2±0.5 to 67.3±0.2 g/l (P <0.05) and in the control group from 61.0±0.2 to 66.1±0.1 g/l (P <0.05), the "Ca" content from 2.1±0.01 to 2.7±0.02 mmol/l (P <0.05) in the experimental group and from 2.0±0.01 to 2.5±0.02 mmol/l (P <0.05) in the control groups, while being within the normal range. The amount of albumin significantly increased only in the experimental group from 40.8±1.2 to 49.3±2.8 g/l (P <0.05), in the control from 42.2±2.1 to 46.0±1.5 g/l (P> 0.05). The number of piglets with low viability in the experimental group was 2 times less than in the control group. The viability of piglets in the experimental group by the time of weaning was 92.6 %, in the control ‒ 83.2 %.

scholarly journals The dynamics of the liver protein-producting function and cytolysis processes during the period of acute reaction to a combined cranio-skeletal trauma

2013 ◽  
Vol 17 (2 (66)) ◽  
pp. 29-33
Author(s):  
A. I. Gozhenko ◽  
R. M. Borys ◽  
A. A. Hudyma
Keyword(s):  
Liver Function ◽  
Characteristic Feature ◽  
Aspartate Aminotransferase ◽  
Alanine Aminotransferase ◽  
Control Group ◽  
Liver Protein ◽  
Skeletal Trauma ◽  
Acute Reaction ◽  
Post Traumatic ◽  
Experimental Group

Experimental cranioskeletal trauma stipulates an impairment of the protein-synthesizing liver function, which is especially noticeable in 12 hours of the post-traumatic period in animals with additional bleeding. The activity of the blood serum aspartate- and alaninaminotransferase essentially exceeds the control levels during all the terms of observation. A characteristic feature of aspartate aminotransferase dynamics in animals with a cranioskeletal trauma without bleeding is reaching by it a statistically significantly higher level pertaining to the control group already in 2 hours, which remains consistently high until the end of the experiment. It elevates in the group with bleeding in the dynamics of the posttraumatic period, and in 24 hours and it essentially exceeds the level present in the experimental group of animals without bleeding. This pattern is also observed in relation to the alanine aminotransferase value.

scholarly journals Toxicological Effects of Aqueous Extract From African Walnut (Tetracarpidium conophorum) Leaves in Rats

2017 ◽  
Vol 22 (4) ◽  
pp. 919-925 ◽  
Author(s):  
Seun F. Akomolafe ◽  
Ganiyu Oboh ◽  
Sunday I. Oyeleye ◽  
Tosin A. Olasehinde
Keyword(s):  
Uric Acid ◽  
Aspartate Aminotransferase ◽  
Alanine Aminotransferase ◽  
Biochemical Parameters ◽  
Inflammatory Cell ◽  
Morphological Changes ◽  
Control Group ◽  
Toxicological Effects ◽  
Significant Difference ◽  
Liver And Kidney

Tetracarpidium conophorum leaves are used in traditional medicine for the treatment of male infertility, without considering its toxicity and side effects. In this study, we investigated the effects of T conophorum leaves on some biochemical parameters such as alanine aminotransferase, aspartate aminotransferase, bilirubin, albumin, creatinine, and uric acid. Histology of the liver and kidney were also assessed. The result revealed that the alanine aminotransferase and aspartate aminotransferase levels of the control group were not significantly different from the experimental groups. There was no significant difference in the albumin and bilirubin levels of the control and experimental groups. Similarly, the uric acid and creatinine levels of the experimental rats were not significantly different from the control. The examination of liver and kidney sections did not show any morphological changes and inflammatory cell infiltrations. These findings suggest that the leaves did not induce any pathological changes at the doses tested.

scholarly journals Effects of feeding graded levels of whole cottonseed on haemato-biochemical parameters of red Sokoto bucks

2020 ◽  
Vol 18 (2) ◽  
pp. 83-90
Author(s):  
J.I. Itodo ◽  
P.I. Rekwot ◽  
T.T. Aluwong ◽  
J.S. Rwuaan ◽  
K.O. Abah ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Total Protein ◽  
Alanine Aminotransferase ◽  
Biochemical Parameters ◽  
Control Group ◽  
Transferase Activity ◽  
Albumin Concentration ◽  
Whole Cottonseed ◽  
Group D ◽  
Aspartate Transferase

Whole cottonseed (WCS) is an important source of protein for ruminants, however, it contains a polyphenolic secondary metabolite gossypol which may reduce its palatability and cause pathophysiological effects. The study was aimed at evaluating the effects of feeding graded levels of WCS on the haemato-biochemical parameters of Red Sokoto bucks (RSB). After a 14-day pre-treatment period, 20 bucks (n = 5) were assigned for 90 days to one of four isonitrogeneous treatments: control (A); 0 % (B); 15 % (C); 30 % and (D); 45 %. Blood was collected for Packed Cell Volume (PCV) and serum analyses at days 0, 45 and 90 of the experimental period for concentrations of urea, creatinine, total protein, albumin, globulin and activities of aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (ALP). The PCV was decreased in groups fed above 15 % of WCS on days 45. There were no significant (P > 0.05) differences in globulin concentration, alanine aminotransferase and alkaline phosphatase activities but aspartate transferase activity was higher (p < 0.05) in group D (45% WCS) compared to the various treatment groups. The urea concentration was higher (p < 0.05) in groups B and D at day 45 compared to the control group. The creatinine concentration was higher (p < 0.05) in group D at days 45 and 90 compared to the control group. The serum total protein and albumin concentration were higher (p < 0.05) in groups C and D at day 45 compared to the control group. Our finding revealed that prolonged feeding of bucks above 30 % WCS for more than 60 days exerted considerable deleterious and adverse effects on blood constituents leading to aneamia, hyper-cretenaemia, ureamia, increased levels of total protein, albumin, aspartate transferase activity and death. Keywords: Biochemical parameters, Bucks, Gossypol, Serum, Whole cotton seed

scholarly journals Effect of silymarin supplementation on some productive and hematological parameters in meat type male Japanese quails

2019 ◽  
pp. 984
Author(s):  
Hristo Lukanov, Ivelina Pavlova ◽  
Veselin Ivanov, Todor Slavov, Yoana Petrova, Nadya Bozakova
Keyword(s):  
Body Weight ◽  
Growth Performance ◽  
Biochemical Parameters ◽  
Hematological Parameters ◽  
Control Group ◽  
Japanese Quails ◽  
Hematological And Biochemical Parameters ◽  
Experimental Group ◽  
Meat Type ◽  
Main Growth

A total of 90 14-day-old meat type male Japanese quails were included in the experiment and equally divided into 3 groups: control group (CG) without treatment, experimental group 1 (EG 0.5%), supplemented with silymarin 0.5% and experimental group 2 (EG 1%), supplemented with silymarin 1%. The aim of the current study was to establish the effect of supplementation with different doses of silymarin extract on the growth performance and some hematological parameters in male Japanese quails. Main growth performance (body weight, feed consumption and weight gain) were examined and FCR was calculated. Some hematological (WBC, RBC, HGB and HTC) and biochemical (triglycerides, AST and ALT) parameters were determined. The highest average body weight was observed in EG 0.5% group at 35-day-old age and the lowest in EG 1%, 239.61±2.96 g and 231.74±2.96 g respectively. The highest values of the weight gain were calculated in EG 0.5% group, 67.02±2.03 g during the first week of fattening and the lowest was observed in EG 1% group at the fifth week after hatching, 23.30±2.03 g respectively. The lowest values of FCR were observed during the first week of the trial, 2.42±0.08 kg/kg to 2.61±0.13 kg/kg in EG 1% and the control group respectively. The supplementation of 0.5% and 1% silymarin did not significantly change the studied hematological and biochemical parameters. A tendency of higher values of triglycerides and lower values of AST and ALT was observed in the groups, supplemented with silymarin compared to the controls. From the obtained results of the present study we can conclude that the silymarin supplementation at higher doses (0.5% and 1%) did not have effect on the main growth performance and some hematological and biochemical parameters of male Japanese quails.

scholarly journals Antioxidative Role of Hatikana (Leea macrophyllaRoxb.) Partially Improves the Hepatic Damage Induced by CCl4in Wistar Albino Rats

2015 ◽  
Vol 2015 ◽  
pp. 1-12 ◽  
Author(s):  
Samina Akhter ◽  
Md. Atiar Rahman ◽  
Jannatul Aklima ◽  
Md. Rakibul Hasan ◽  
J. M. Kamirul Hasan Chowdhury
Keyword(s):  
Alkaline Phosphatase ◽  
Liver Injury ◽  
Total Protein ◽  
Aspartate Aminotransferase ◽  
Alanine Aminotransferase ◽  
Biochemical Parameters ◽  
Lipid Profiles ◽  
Scavenging Effect ◽  
Serum Aspartate Aminotransferase

This research investigated the protective role ofLeea macrophyllaextract on CCl4-induced acute liver injury in rats. Different fractions ofLeea macrophylla(Roxb.) crude extract were subjected to analysis for antioxidative effects. Rats were randomly divided into four groups as normal control, hepatic control, and reference control (silymarin) group and treatment group. Evaluations were made for the effects of the fractions on serum enzymes and biochemical parameters of CCl4-induced albino rat. Histopathological screening was also performed to evaluate the changes of liver tissue before and after treatment. Different fractions ofLeea macrophyllashowed very potent 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging effect, FeCl3reducing effect, superoxide scavenging effect, and iron chelating effect. Carbon tetrachloride induction increased the level of serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP) and other biochemical parameters such as lipid profiles, total protein, and CK-MB. In contrast, treatment ofLeea macrophyllareduced the serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP) activities as well as biochemical parameters activities.L. macrophyllapartially restored the lipid profiles, total protein, and CK-MB. Histopathology showed the treated liver towards restoration. Results evidenced thatL. macrophyllacan be prospective source of hepatic management in liver injury.

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