scholarly journals Studies on some Biochemical Parameters among Charcoal (Physiculus nematopus) Traders in Swali Market Yenagoa Bayelsa State

2021 ◽  
Vol 6 (3) ◽  
pp. 74-80
Author(s):  
E.T. Egoro ◽  
E.S. Oni ◽  
J.O. Otaraku ◽  
D.E. John
Keyword(s):  
Aspartate Aminotransferase ◽  
Alanine Aminotransferase ◽  
Biochemical Parameters ◽  
Medical Laboratory ◽  
Control Group ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Laboratory Facility ◽  
Blood Specimens ◽  
Experimental Group

The aim of this study was to assess some biochemical parameters among charcoal (Physiculus nematopus) traders in Swali market Yenagoa Bayelsa State, Nigeria. Five milliliter of blood specimens was collected from each of the fifteen charcoal (Physiculus nematopus) traders with < 5 years working experience (experimental group one), fifteen charcoal (Physiculus nematopus) traders with ≥5 years working experience (experimental group two) and fifteen non charcoal traders (control group) into lithium heparin anti-coagulated bottles respectively. Thereafter alanine aminotransferase (ALT), aspartate aminotransferase (AST), urea, creatinine and C-reactive protein (CRP) were measured quantitatively. The results of charcoal traders in experimental group one showed no statistically significant differences (p>0.05) in all the measured biochemical parameters ALT (7.26U/I), AST (5.61U/I), CRP (2.48mg/L), urea (8.68mmol/L), creatinine (82.14µmol/L) as compared to that of the control group (7.22U/I), (5.58U/I), (2.47mg/L), (8.65mmo/L), (82.10µmol/L) respectively while that of experimental group two showed statistically significant differences (p<0.05) in alanine aminotransferase (20.40U/I), aspartate aminotransferase (16.20U/I) and C-reactive protein (22.42mg/L) as compared to that of the control group (7.22U/I), (5.58U/I), (2.47mg/L) respectively. However, urea (8.68mmol/L) and creatinine (82.25µmol/L) showed no statistically significant differences (p>0.05) as compared to that of the control group (8.65mmol/L), (82.10µmol/L) respectively. In conclusion alanine aminotransferase, aspartate aminotransferase and C-reactive protein may be altered in charcoal (Physiculus nematopus) traders exposed to charcoal dust for ≥ 5 years. It is therefore recommended that charcoal traders in this category should embark on hepato-inflammatory biochemical parameters investigation intermittently in any registered and licensed Medical Laboratory facility so as to monitor the concentrations of these parameters.

scholarly journals Occupational effect of spray painting fumes on some biochemical parameters in automobile spray painters in Yenagoa Bayelsa State, Nigeria

2021 ◽  
Vol 9 (2) ◽  
pp. 038-044
Author(s):  
Emmanuel Tonbra Egoro ◽  
Emmanuel Sunday Oni ◽  
Jonathan Ebipade Lawrence
Keyword(s):  
Aspartate Aminotransferase ◽  
Alanine Aminotransferase ◽  
Biochemical Parameters ◽  
Control Group ◽  
Chemical Toxicity ◽  
C Reactive Protein ◽  
Spray Painting ◽  
Plasma Urea ◽  
Reactive Protein ◽  
Experimental Group

Automobile spray painters are often prone to chemical toxicity due to their routine work. This study was aimed at the occupational effect of spray painting fumes on some biochemical parameters in automobile spray painters. Five milliliters of blood specimen were collected into lithium heparin anti-coagulated bottles from twenty five automobile spray painters with ≤ 10 years working experience (experimental group one), ≥ 11 years working experience (experimental group two) and non-automobile spray painters which were monitored as control group respectively. After this, plasma alanine aminotransferase, aspartate aminotransferase, C-reactive protein, urea and creatinine were measured quantitatively using a spectrophotometer. The mean values of all the measured biochemical parameters showed no statistically significant differences (p>0.05) in the automobile spray painters with ≤ 10 years working experience as compared with that of the control group with the exception of plasma C-reactive protein, while those with ≥ 11 years working experience showed statistically significant differences (p<0.05) in plasma alanine aminotransferase, aspartate aminotransferase and C-reactive protein however, the plasma urea and creatinine showed no statistically significant differences (p>0.05). In conclusion, the concentration of plasma alanine aminotransferase, aspartate aminotransferase and C-reactive protein may be altered in automobile spray painters with ≥ 11 years working experience, thus these biochemical parameters should be monitored regularly in spray painters within this category of working experience

scholarly journals Assessment of selected biochemical parameters among food hawkers along the streets of Yenagoa Bayelsa State, Nigeria

2021 ◽  
Vol 16 (3) ◽  
pp. 103-108
Author(s):  
Emmanuel Tonbra Egoro ◽  
Emmanuel Sunday Oni ◽  
Otaraku Jonathan Oye ◽  
Annabel Awele Idama
Keyword(s):  
Aspartate Aminotransferase ◽  
Alanine Aminotransferase ◽  
Biochemical Parameters ◽  
Control Group ◽  
C Reactive Protein ◽  
Mean Values ◽  
Reactive Protein ◽  
Significant Difference ◽  
The Mean ◽  
Experimental Group

This study was aimed on assessment of selected biochemical parameters among food hawkers along the streets of Yenagoa, Bayelsa State, Nigeria. Five milliliter of blood specimen was collected from fifteen food hawkers with ≤ 5 years working experience (experimental group one), ≥ 5 years working experience (experimental group two) and nonfood hawkers (control group) respectively into lithium heparin anti-coagulated bottles. Thereafter alanine aminotransferase, aspartate aminotransferase, urea, creatinine and C-reactive protein were measured quantitatively. The mean values of volunteers in experimental group one showed no statistically significant difference (p>0.05) in alanine aminotransferase (7.46 ± 1.02), aspartate aminotransferase (7.02 ± 0.86), urea (7.70 ± 1.29) and creatinine (70.44 ± 3.54) as compared with the control group (7.42 ± 0.98), (6.98 ± 0.82), (7.65 ± 1.28) and (70.40 ± 3.52) respectively, but there was a statistically significant difference (p<0.05) in C-reactive protein (17.40 ± 1.98) when compared with the control group (2.70 ± 0.70). However, the mean values of food hawkers in experimental group two showed statistically significant difference (p< 0.05) in all the measured biochemical parameters 27.70±2.98, 21.40±2.06, 15.50±2.02, 110.70±3.74, 29.42±3.20 as compared with that of the control group 7.42±0.98, 6.98±0.82, 7.65±1.28, 70.40±3.52, 2.74±0.70. The volunteers in experimental groups one and two showed 13% -27% and 53% -80% abnormal values of the measured biochemical parameters respectively as compared with that of the control group. In conclusion, alanine aminotransferase, aspartate aminotransferase, urea, creatinine and C-reactive protein may be altered in food hawkers with ≥ 5 years working experience. It is therefore recommended that food hawkers in this category should go for hepato-renal and inflammatory biochemical parameters checkup occasionally in any registered and licensed Medical Laboratory Facility.

scholarly journals Effect of Xanthohumol Added to Diet on Blood Biochemistry in Japanese Quails

2021 ◽  
Vol 9 (6) ◽  
Author(s):  
Zuzana Lacková ◽  
František Zigo ◽  
Zuzana Farkašová
Keyword(s):  
Enzyme Activity ◽  
Total Protein ◽  
Aspartate Aminotransferase ◽  
Alanine Aminotransferase ◽  
Biochemical Parameters ◽  
Blood Biochemistry ◽  
Control Group ◽  
Japanese Quails ◽  
Experimental Group ◽  
Alt Alanine Aminotransferase

In this paper, we monitored to effect of xanthohumol added to diet on blood biochemistry in Japanese quails. Forty Japanese quails breeds lines Pharaoh were included in the experiment. The quails were randomly divided into two groups: one control and one experimental group with supplementation by xanthohumol in feed. In the evaluation of biochemical parameters, we focused on total protein, albumin, globulin, glucose, cholesterol and enzyme activity of AST (Aspartate aminotransferase), ALT (Alanine aminotransferase) and ɤ-GT (ɤ-Glutamyltransferase). Statistical comparisons were made between group with supplementation by xanthohumol in feed and the control group. Total protein and albumin levels were significantly differed between groups (P <0.05). A significant decrease in AST activity (P <0.05) was observed in supplementation group relative to control group.

scholarly journals Effects of indiscriminate consumption of paracetamol (acetaminophen) on selected biochemical parameters in Rattus norvegicus rats

2020 ◽  
Vol 13 (3) ◽  
pp. 054-063
Author(s):  
Emmanuel Tonbra Egoro
Keyword(s):  
Rattus Norvegicus ◽  
Therapeutic Dose ◽  
Biochemical Parameters ◽  
Daily Basis ◽  
Toxicity Study ◽  
Control Group ◽  
Mean Values ◽  
Reactive Protein ◽  
Blood Specimens ◽  
Experimental Group

Paracetamol (acetaminophen) is a well-known medication for the treatment of pain and fever. The aim of this study was to assess the effects of its indiscriminate consumption on selected biochemical parameters in Rattus norvegicus rats with a view to relate the findings to humans. The data obtained from the human volunteers within the age range of 20-67years revealed that paracetamol (acetaminophen) is indiscriminately consumed mainly by traders as compared with other painkillers in the study communities. Five milliliters of blood specimens were withdrawn from Rattus norvegicus rats administered with 500 mg/2ml paracetamol (acetaminophen) for one day, acute toxicity study (experimental group one), 50 mg/2ml paracetamol (acetaminophen) on daily basis for thirty days, sub-chronic toxicity study (experimental group two), 50mg/2ml paracetamol (acetaminophen) on daily basis for three days, recommended therapeutic dose (experimental group three) and control group respectively. Thereafter, aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, urea, creatinine, C-reactive protein and testosterone were measured using a spectrophotometer. The mean values of all the measured biochemical parameters in both experimental group one and two rats revealed statistically significant differences (p<0.05) with experimental group three rats being exception (p>0.05) as compared with that of the control group which may be suggestive of hepatic, renal, inflammatory and spermatogenesis disorders. Though the consumption of this tablet at recommended therapeutic dose was well tolerated by the rats as against its indiscriminate consumption which posed danger on the rats thus it is recommended that this tablet should be taken strictly on the prescription of a physician or health professional.

scholarly journals Metabolic and Functional Profile of Premenopausal Women With Metabolic Syndrome After Training With Elastics as Compared to Free Weights

2016 ◽  
Vol 19 (2) ◽  
pp. 190-197 ◽  
Author(s):  
Jorge Flandez ◽  
Noelia Belando ◽  
Pedro Gargallo ◽  
Julio Fernández-Garrido ◽  
Ronald A. Vargas-Foitzick ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Premenopausal Women ◽  
Control Group ◽  
Positive Trend ◽  
C Reactive Protein ◽  
Functional Profile ◽  
Reactive Protein ◽  
Almost All ◽  
Sedentary Women ◽  
Experimental Group

The aim of this study was to compare the effects of a strength training program (STP) using free weights (FW) versus elastic tubing (ET) in 62 premenopausal, sedentary women diagnosed with metabolic syndrome (MS). Participants were randomly assigned to the FW or ET experimental group (EG) or a control group whose members remained sedentary. Members of each EG followed their assigned STP for 12 weeks, and biomarkers (BMs) related to MS and motor function (MF) parameters were evaluated. Both EGs showed a significant reduction in C-reactive protein level and a positive trend in the other BMs. Almost all MF parameters increased significantly in both EGs. No positive changes were found in the CG. These results indicate that the implementation of an STP, with either FW or ET, improves both metabolic health and MF and should be considered part of the basic approach to health care in women.

scholarly journals Protein-synthesizing function and functional state of the liver of dogs at experimental toxocariasis

2020 ◽  
Vol 22 (98) ◽  
pp. 132-137
Author(s):  
W. S. Said ◽  
V. V. Stybel ◽  
B. V. Gutyj ◽  
O. B. Pryima ◽  
I. Y. Mazur
Keyword(s):  
Body Weight ◽  
Functional State ◽  
Total Protein ◽  
Aspartate Aminotransferase ◽  
Alanine Aminotransferase ◽  
Experimental Studies ◽  
Control Group ◽  
Activity Of Enzymes ◽  
Experimental Group

The aim of the study was to investigate the effect of toxocariasis invasion on protein-synthesizing function and functional state of the liver of dogs. For experimental studies, 12 dogs aged from two to four months were used and two groups of six animals were formed in each: control and experimental. Puppies of the experimental group were experimentally infected with the pathogen toxocariasis at a dose of 5,000 invasive eggs of T. canis per kg of body weight. The control puppies were clinically healthy. Protein-synthesizing function of the liver of dogs in experimental toxocariasis was studied by the level of total protein and its fractions. It was found that on the 25th day of the experiment the level of total protein in the blood of the experimental group of dogs was 56.9 ± 1.47 g/l, while in the control group – 63.8 ± 2.92 g/l. The lowest level of the studied indicator was on the 30th day of the experiment in the blood of the experimental group of dogs, where it decreased by 9.6 %. The results of a study of protein fractions in the blood of dogs infested with toxocara showed that the percentage of albumin is likely to decrease. However, in the blood of infected dogs in this period of research there was a probable increase in globulin levels. The study of the effect of toxocariasis invasion on the activity of enzymes in blood serum is a test for the morphological and functional state of tissues and organs. Based on the studies, it was found that with the development of toxocariasis invasion in dogs there is an increase in alanine aminotransferase in their serum. On the 25th and 30th day of the experiment, the activity of the enzyme in the serum of infected dogs was the highest, where compared with the control group of dogs, the activity of ALT increased by 51.2 and 59.1 %, respectively. Similar changes in activity were observed in the determination of aspartate aminotransferase, where, respectively, on the 15th, 20th and 25th day of the experiment, the activity of AST in the serum of infected dogs increased by 19.3, 27.5 and 39.1 %.

scholarly journals Clinical Evaluation of Some Biochemical Parameters from Patients in Heamodialysis Room

2010 ◽  
Vol 7 (1) ◽  
pp. 757-765
Author(s):  
Baghdad Science Journal
Keyword(s):  
Blood Sugar ◽  
Systemic Inflammation ◽  
Biochemical Parameters ◽  
Normal Subjects ◽  
Biochemical Parameter ◽  
Renal Diseases ◽  
Control Group ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Chronic Renal Diseases

As a marker of systemic inflammation, raised (C-reactive protein (CRP)) concentrations which are still within the normal range have been associated with an increased inflammation of chronic renal diseases (CRD). The current study aimed to establish potential determinats of raised CRP concentrations in patients who treated in Heamodialysis room,then study the relationship between CRP& some biochemical parameters related CRD We used a CRP latex reagents Kit which is based on an immunological reaction between CRP antisera bounded to the biologically inert latex particles or with CRP in the test specimens of 19 patients with (CRD) mean age 48 years ,range = 30?65 & in 21 healthy subjects as control group their age range = 30 ?45 years. The results are classified according to visible agglutination to: 1-A positive result / is indicated by the obvious agglutination pattern of the latex, in a clear solution. 2-A negative result / is indicated by no change in the latex suspension on the test slide. Then, we correlated the results of the precipitin test with the quantitative data on C-reactive protein. This study has found that: CRP concentrations in patients with CRD were increased very clearly than normal subjects , and established that CRP concentration in male was more than in female for patients specimens. Biochemical studies have shown raising (CRP) concentration is a marker of systemic inflammation. The relation between CRP & S.creatinine ,hemoglobine ,blood sugar is negative ,while positive with blood urea . Other biochemical parameter related to CRD'' blood urea, blood creatinine & hemoglobine and blood sugar'' were assayed for both subjects in order to asses the disease by compared the results. Abbreviation: CRP:C-reactive protein, CRD: Chronic renal diseases, F: Female, M: Male, Hb: hemoglobin, BU: blood Urea, S.Cr: Serum creatinine, BS: blood sugar, nCRP: native CRP, MCRP: Matified CRP.

scholarly journals Abuse of Alabukun consumption: A biochemical and histomorphological study in Rattus norvegicus rats

2021 ◽  
Vol 8 (1) ◽  
pp. 037-042
Author(s):  
Emmanuel TonbraEgoro ◽  
Ikhide Godwin Ilegbedion ◽  
Prudence NkemdinimOkara
Keyword(s):  
Rattus Norvegicus ◽  
Daily Basis ◽  
Control Group ◽  
C Reactive Protein ◽  
Biochemical Finding ◽  
Mean Values ◽  
Reactive Protein ◽  
The Mean ◽  
Kidney Liver ◽  
Experimental Group

This study was aimed on the biochemical and histomorphological study of abuse in the consumption of alabukun powder in Rattus norvegicus rats. Five milliliter of blood specimen was collected into lithium heparin bottles from seven rats weighing 240±2g respectively with each of them administered with 0.2mg/kg alabukun powder daily for a period of two weeks (experimental group) while another seven rats weighing 240±2g each were not administered with alabukun powder (control group). Thereafter alanine aminotransferase, aspartate aminotransferase, urea, creatinine and C-reactive protein were measured quantitatively in both groups of rats. The mean values of all the measured biochemical parameters in Rattus norvegicus rats in the experimental group were statistically significant (p<0.05) as compared to that in the control group. This established biochemical finding was in conformity with the histomorphological examination of the kidney and liver organs. In conclusion, this study has established that administration of 0.2mg/kg of alabukun powder on daily basis for a period of two weeks on Rattus norvegicus rats may induce hepato-renal and inflammatory disorders. It is thus recommended that consumption of alabukun powder by humans should strictly be in compliance with its prescription. However, kidney, liver and inflammatory biomarkers should be quantitatively measured in humans that have abused its consumption with a view to ascertain their health status and prevent any deleterious risks.

scholarly journals Clinical and anamnestic characteristics of patients with non-ST elevation myocardial infarction after COVID-19

2021 ◽  
Vol 20 (7) ◽  
pp. 3062
Author(s):  
M. G. Chashchin ◽  
A. Yu. Gorshkov ◽  
O. M. Drapkina ◽  
I. V. Kositsyna ◽  
A. V. Golubev ◽  
...  
Keyword(s):  
Myocardial Infarction ◽  
Troponin I ◽  
St Elevation Myocardial Infarction ◽  
Control Group ◽  
C Reactive Protein ◽  
Reactive Protein ◽  
Exertional Angina ◽  
History Of ◽  
St Elevation ◽  
Experimental Group

Aim. To study clinical, medical history and paraclinical characteristics of patients with non-ST elevation myocardial infarction (NSTEMI) after coronavirus disease 2019 (COVID-19).Material and methods. The study included 209 patients with NSTEMI who were admitted to the Demikhov City Clinical Hospital (Moscow). The patients were divided into 2 groups: the experimental one (n=104)  — those after COVID-19, the control one (n=105)  — those without history of COVID-19. All patients underwent routine diagnostic investigations in accordance with current standards and clinical guidelines.Results. The mean age of patients in the experimental group was 61,8±12,2 years, while in the control one — 69,0±13,0 years (p<0,0001). Myocardial infarction developed 49 days [34.0; 82.0] after COVID-19. Prior exertional angina was observed in 76,9% of patients in the experimental group and in 88,6% in the control one (χ2 =4,97; p=0,0258). The level of C-reactive protein in the experimental group was 19,2 mg/l [4,9; 53,0], and in the control one — 5,6 mg/l [0,4; 21,8] (p=0,0007). The average troponin I level in the experimental group was 2,7 ng/ml [1,3; 8,0], while in the control one — 1,8 ng/ml [0,8; 3,5] (p=0,0091).Conclusion. Patients with NSTEMI after COVID-19 were significantly younger compared to patients without a history of COVID-19. They had less common exertional angina prior to MI, while C-reactive protein and troponin I levels were significantly higher than in the control group. In addition, in NSTEMI patients after COVID-19, the estimated pulmonary artery systolic pressure was significantly higher compared to patients without a history of COVID-19.

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