scholarly journals Comparison of Hepcidin Levels in Children with and without Soil-Transmitted Helminths Infection

Author(s):  
Dewi Saputri ◽  
Yunilda Andriyani ◽  
Almaycano Ginting

Helminths infection is one of the diseases that still occur insociety. The helminth infection caused by theSoil-Transmitted Helminths (STHs) group, which is Ascaris lumbricoides, Trichuris trichiura, and hookworm in human cancause chronic bleeding resulting in decreasir on storage in the body and increased level of hepcidin. Hepcidin is a liverhormone which regulates iron metabolism and can function as marker of inflammation and iron deficiency. This study aimedto compare the hepcidin levels in STH-infected and non-infected children. A cross-sectional study was conducted betweenMay and October 2018 on 28 STH infected and 140 non-infected subjects. The collected stool samples were analyzed usingthe Kato-Katz method to determine the presence of STH infection and the degree of infection. Urine samples wereprocessed, and their hepcidin levels were measured using a Sandwich-ELISA method. Measurement was made using aSpectrophotometer. The difference of numeric variables was analyzed using Wilcoxon test. The prevalence of STH infectionwas 16.66%. The prevalence of Trichuris trichiura 10.71%, Ascaris lumbricoides 4.76% and hookworm 2.97%. The prevalenceof a single infection was 14.88% and mixed infection 1.78%. Based on the intensity of infection, 15.48% of subjects were mildinfection, 0.59% moderate infection, and 0.59% severe infection. Hepcidin levels in the infected and uninfected group didnot differ significantly (p=0.978). There were no different hepcidin levels in children with and without soil-transmittedhelminths infection.

2019 ◽  
Vol 32 (11-12) ◽  
pp. 312-7
Author(s):  
Erliana Malik Miraza ◽  
Abdul Gani ◽  
Mardiana Karim Dj. ◽  
Iskandar Z. Lubis ◽  
Chairuddin P. Lubis

A descriptive cross sectional study on intestinal parasitic infestation was earned out among children of three kindergartens (Methodist, Dharma Wanita and Aisyiah) in Medan. Of 162 samples of feces examined mixed infestations with Ascaris lumbricoides and Trichuris trichiura was found in 14,25%, single infestations of Trichuris trichiuria in 14,2%, AScaris lumbricoides in 13,0%, H. nana in 1,2% and G. Iamblia in 0,6%. Hookworm infestation was not found among preschool children in all of those three kindergartens.


Author(s):  
Theodore Vassilikopoulos ◽  
Athena Kalokairinou ◽  
Georgia Kourlaba ◽  
Eirini Grapsa

The purpose of this study was to investigate the level of renal function knowledge of primary school pupils in Greece. We conducted a cross-sectional study with a convenience sample of 220 pupils, coming from the 5th and 6th grades of general education schools. A questionnaire consisting of 11 questions was developed from scratch. However, based on an analysis of Cronbach’s alpha values obtained when individual questions were deleted, two questions were removed from the analysis, and only nine remained for analysis and participated in the calculation of the knowledge score. Moreover, the gender and daily habits of pupils regarding water consumption and frequency of urination were recorded. Pupils had a high percentage of correct knowledge about the number of kidneys (95.2%), whether a child may have problems with the kidneys (85.5%) and whether a person can survive with one kidney (68.5%). Low levels of knowledge were observed in the function and role of the kidneys (36.4%), as well as the part of the body where the kidneys are located (30.9%). The median (interquartile range (IQR)) total knowledge score was 6 (5–7), with no difference detected between genders (p = 0.135). A statistically significant difference between pupils of 5th and 6th grades was found but the difference did not seem to be clinically significant (p = 0.035). The present research demonstrates that pupils’ knowledge of renal function and the protection of their kidneys needs improvement.


Author(s):  
Golnaz Arjmand ◽  
Pardis Irandoost ◽  
Mojtaba Abbaszadeh ◽  
Aliasghar Farshad ◽  
Masoud Salehi ◽  
...  

Background: Musculoskeletal disorder (MSD) is one of the important problems concerning the staffs' health and productivity in the workplace. Nutritional status and consumption of some foods are also among the determining factors of MSD. So, this study aimed to evaluate the correlation of diet and consumed food groups with MSD. Methods: This cross-sectional study was conducted on 100 office workers. The participants' anthropometric parameters and their dietary information were collected using a semi-quantitative food frequency questionnaire. The findings were categorized into nine levels. The total scores were calculated for all the items per food group and per person. Nordic musculoskeletal questionnaire was also administered to evaluate the MSD symptoms in nine parts of body. Results: The score of consumed food groups was compared between individuals “with pain” and “without pain” in nine parts of the body. The scores of fruit intake in individuals “with pain” and “without pain” were 2.94 ± 1.27 vs. 3.29 ± 1.16 and 2.81 ± 1.10 vs. 3.49 ± 1.38 in terms of neck and wrists, respectively. The difference between the two groups were significant (P < 0.05). Furthermore, the participants with pain in the neck consumed significantly lower amounts of cereals and nuts (P = 0.03, 0.04). In the case of the shoulder pain, consuming legumes and nuts in the “without pain” group was higher than the group of participants who had pain (P = 0.01, P = 0.03). Fat intake was higher in the patients who had pain in their hips (P = 0.02). Conclusion: Less pain was reported in the musculoskeletal system by higher consumption of fruits, nuts, and legumes. It seems that plant-based dietary pattern is more effective in musculoskeletal health.


2019 ◽  
Vol 7 (5) ◽  
Author(s):  
Ni Putu Aryadnyani ◽  
Warida Warida ◽  
Mega Mirawati

Soil-Transmitted Helminthiasis is caused by nematode worm infections, namely Ascaris lumbricoides (round worm), Trichuris trichiura (whipworm) and Necator americanus or Ancylostoma duodenale (hookworm). At present, the prevalence of Soil-Transmitted Helminthiasis in Indonesia is still high. To reduce the prevalence of Soil-Transmitted Helminthiasis in Indonesia, the Ministry of Health of the Republic of Indonesia holds a mass worm treatment program for pre-school age children and school-aged children. The drug given is albendazole 400 mg single dose. This study aimed to determine the effectiveness of a single dose of albendazole 400 mg against infections of Ascaris lumbricoides and Trichuris trichiura. This study used a Pre-Experiment research design (One Group Pretest-Posttest). The research subjects were 66 people. Subjects positive for Ascaris lumbricoides were 37 people (mild infection 67.57%, moderate infection 27.03% and severe infection 5.41%). After giving a single dose of albendazole 400 mg to 37 people who were positive for Ascaris lumbricoides, 37 people had not found eggs of Ascaris lumbricoides on faecal examination after treatment. Positive subjects Trichuris trichiura were 54 people (mild infections 51.85%, moderate infections 44.44% and severe infections 3.73%). After giving a single dose of albendazole 400 mg to 54 positive people Trichuris trichiura, in severe infections, the percentage of eggs dropped was 100%. In moderate infections, the percentage of the number of eggs dropped is 95.83%. In mild infections, the percentage of total recovery was 7.14%, and the percentage of eggs dropped was 39.29%. The results of the Wilcoxon test on Ascaris lumbricoides obtained a significance value of <0.05, which means that there are significant differences in the examination before treatment and after treatment. The results of the Wilcoxon test on Trichuris trichiura obtained a significance value of 0.05, which means there were no significant differences in the results of the examination before treatment and after treatment. Albendazole 400 mg single dose is effective against Ascaris lumbricoides infection and is not effective against Trichuris trichiura infection.


2014 ◽  
Vol 2 (2) ◽  
Author(s):  
Ivanny Kasenda ◽  
Sylviah Marunduh ◽  
Herlina Wungouw

Abstract: The pulse is a pressure that is delivered in the form of a wave when the heart pumped up blood around the body.  Pulse is determined by the elasticity of blood vessels.  There are research showing the difference in pulse rate in the highlands and lowlands.  This research aimed to determine the ratio between the pulse of the people that live in the highlands (mountain area) and lowlands (coastal area). This research is an analytic method using cross sectional study.  The subjects of this research is 80 people living in the highlands and 80 people living in the lowlands.  The subjects are 18-65 years, physically and mentally healthy and they have been living at the area for 5 years.  The data were analyzed using non-parametric test Mann Whitney test. Based on the results of the Mann Whitney statistical test, it shows that there is a difference between the result  of pulse measurement  of the people living in the highlands and lowlands with asymp value. Sig. (2-tailed) α = 0:03 (α <0.05), which means that there are significant difference between highlands and lowlands. The result of this research can be concluded that there is a significant difference in the measurement of the pulse between people living in the highlands and lowlands. Keywords: Pulse, highlands, lowlands.     Abstrak: Denyut nadi adalah suatu tekanan yang dihantarkan dalam bentuk gelombang saat darah dipompa jantung ke seluruh tubuh. Denyut nadi ditentukan oleh elastisitas pembuluh darah. Terdapat penelitian yang menunjukkan adanya perbedaan denyut nadi di dataran tinggi dan dataran rendah. Penelitian ini bertujuan untuk mengetahui perbandingan denyut nadi  antara penduduk yang tinggal di dataran tinggi (daerah pegunungan) dan dataran rendah (daerah pesisir pantai). Jenis penelitian ini adalah bersifat metode analitik dengan pendekatan rancangan cross sectional study. Subjek dari penelitian ini adalah 80 orang yang tinggal di dataran tinggi dan 80 orang yang tinggal di dataran rendah. Subjek berumur 18- 65 tahun, sehat jasmani dan rohani serta tinggal menetap 5 tahun. Data di analisis menggunakan uji non parametrik yaitu uji Mann Whitney. Berdasarkan hasil uji statistik Mann Whitney menunjukkan bahwa ada perbedaan hasil pengukuran denyut nadi antara penduduk yang tinggal di dataran tinggi dan dataran rendah dengan nilai asymp. Sig. (2-tailed) α = 0.03(α < 0.05) yang berarti terdapat perbedaan yang bermakna antara dataran tinggi dan dataran rendah. Hasil penelitian ini dapat disimpulkan bahwa terdapat perbedaan yang bermakna pada pengukuran denyut nadi antara penduduk yang tinggal di dataran tinggi dan dataran rendah. Kata kunci denyut nadi, dataran tinggi, dataran rendah.


2012 ◽  
Vol 3 (1) ◽  
pp. 39-44 ◽  
Author(s):  
MA Alim ◽  
MK Islam ◽  
MMH Mondal

A cross sectional study on Fasciola gigantica and Gigantocotyle explanatum burdens in buffaloes in relation to their age, sex and health condition was carried out in the Laboratory of Parasitology, Bangladesh Agricultural University, Mymensingh, Bangladesh during the period from June to November 1997. A total of 460 faecal samples were examined to determine the egg per gram of faeces (epg) of F. gigantica. Higher epg was counted in female buffaloes (159.67 ± 6.80) than in males (153.24 ± 8.29). The epg counts were also found significantly (p < 0.01) higher in poor conditioned buffaloes (164.41 ± 6.67) than in buffaloes with normal health (128.57 ± 7.08). In relation to age, the young adult buffaloes were found to bear more parasitic burdens. The highest mean epg was recorded in the buffaloes of 2-3 years old (184.21 ± 19.14), followed by 3-5 years old (169.23 ± 30.77). The older buffaloes had relatively lower parasitic burden and the lowest mean epg was recorded in the growing buffaloes of up to 1 year old (125 ± 25.0). Examination of 106 livers from slaughtered buffaloes, revealed that the load of Fasciola gigantica and Gigantocotyle explanatum in the livers ranged from 13-424 (69.20 ± 6.46) and 41-427 (161.45 ± 10.79) respectively. In males the burden of F. gigantica (13-210) was lower than that of the females (15-424). The mean number of F. gigantica in the buffaloes of 5- 10 years old (100 ± 15.32) was significantly higher (p < 0.01) than those of the buffaloes of above 10 years old (52.92 ± 4.29). In case of single infection with F. gigantica, the mean number of parasites per liver was significantly (p < 0.05) higher (88.70 ± 11.48) than that of mixed infection cases (49.74 ± 4.20). Significantly (p < 0.01) higher number of G. explanatum was recovered from the buffaloes of 5-10 years old (207.53 ± 26.72) than from the buffaloes of above 10 years old (141.58 ± 9.23) and from single infected cases than from buffaloes with mixed infection. There were almost no differences in the number of both flukes in relation to sex of buffaloes. The length and breadth of immature and mature parasites were 5-15 min x 2-3 min and 16-72 mm x 4-14 mm respectively. No significant variation was found in the average size of F. gigantica in relation to the age and sex of buffaloes. But in case of single infection, the body size of mature F. gigantica (38.63 mm ± 0.38 mm x 9.96 mm ± 0.12 mm) was significantly (p < 0.05) higher than that of the mixed infection (33.68 mm ± 0.52 mm x 8.76 mm ± 0.07 mm) cases. This study fairly suggests that the young adult buffaloes harbour more F. gigantica parasites than their younger and older counterparts. The concomitant infection of buffaloes with F. gigantica and G. explanatum may hamper the parasites each other in establishing their infection and attaining growth in some way as measured by their burdens and morphological dimensions.


2021 ◽  
Vol 1 (S1) ◽  
pp. s63-s63
Author(s):  
Roberta Bosco ◽  
Gabriele Messina ◽  
Davide Amodeo ◽  
Gabriele Cevenini ◽  
Simona Gambelli

Background: Disinfection procedures are an essential aspect of preventing cross contamination, especially in situations where the risk of infection is higher, such as in operating rooms (ORs). Disinfection procedures in ORs at the end of each surgery session are not the same as final cleaning procedures. We assessed the difference in microbial contamination between different levels of disinfection, before T(0) and after T(1) the use of an ultraviolet C device (UVC-D). Methods: A cross-sectional study was conducted between December 2019 and August 2020 in a private clinic. Three sanitation levels (SL1–SL3) were compared for the reduction in colony-forming units (CFU) between T(0) and T(1): (1) no disinfection after surgery (SL1);, (2) after in-between cleaning (SL2), and (3) after terminal cleaning (SL3). UVC-D was used for 6 minutes, 3 minutes per bed side. Overall, 260 Petri dishes were used in 3 ORs, incubated at 36°C, and CFU were counted after 48 hours. Descriptive statistics, Wilcoxon test, and MANOVA for repeated measures were performed to verify the 95% statistical difference between T(0) and T(1), both on the whole sample and combined with the different SLs. Results: The unstratified analysis showed statistically significant differences (Wilcoxon test, p < 0.05) between T(0) and T(1), with means and standard deviations of 11.42 ± SD 41.19 CFU/PD and 5.91 ± SD 30.89, respectively. The Manova test for repeated measures, applied to 54 pairs of measurements, showed no significant difference between SLs in T(0)-T(1) CFU reduction. Overall, the mean percent reduction in CFU was 93.48% (CI95% = 86.97-99.99%). Conclusions: The results showed significant improvements in disinfection under any condition tested with UVC-D. Using the device immediately after surgery (SL1), before standard cleaning procedures, reduced CFUs by 97.3%. In some situations, UVC light was sufficient to reduce CFU to zero, even without chemical and mechanical cleaning. However, we do not recommend this approach; UVC light disinfection should be applied only after sanitization procedures because it does not remove dirt.Funding: UltraViolet Device, IncDisclosures: None


2021 ◽  
Author(s):  
Gong Rongpeng ◽  
Zixin Xu ◽  
Xiaoxin Wei

Abstract BackgroundPrevious studies have shown that hyperuricemia is involved in diabetes, obesity, hypertension, chronic kidney disease, and other diseases. At the same time, studies have shown that vitamin D3 levels in the body are linked to the onset of diabete. However, there is currently no sufficient evidence to prove whether this connection is affected by uric acid levels. Therefore, we attempted to investigate the relationship between vitamin D3 content and the occurrence of diabetes in the hyperuricemia population by using the data of the NHANES database from 2009 to 2018.MethodWe conducted a cross-sectional study using the NHANES database. According to strict inclusion and exclusion criteria, we finally selected 3543 representative data. Multivariate logistic regression analysis was used to explore the relationship between vitamin D3 and diabetes in the hyperuricemia population after complete adjustment. We found a linear relationship between vitamin D3 content and the incidence of diabetes.ResultThe results of this study showed that there was a correlation between the content of vitamin D3 and the incidence of diabetes in people with hyperuricemia, and the effect values (OR and 95% confidence interval) were 0.95and (0.92-0.98), respectively, and the difference was statistically significant.ConclusionOur study shows that vitamin D3 content is associated with the incidence of diabetes in people with high uric acid. This study provides a new idea for exploring the factors affecting the pathogenesis of diabetes in patients with hyperuricemia.


2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Fernanda Silveira Bello de Barros ◽  
Luiz Cláudio de Silva Bussamra ◽  
Edward Araujo Júnior ◽  
Leonardo da Silva Valladão de Freitas ◽  
Luciano Marcondes Machado Nardozza ◽  
...  

To compare the fetal cerebellum and cisterna magna length measurements by means of two- (2DUS) and three-dimensional (3DUS) ultrasonography using the three-dimensional extended imaging (3D XI), a cross-sectional study with 69 healthy pregnant women between 18 and 24 weeks was performed. For the measurements by 2DUS, the axial planes were used and for the 3DUS a sequence of adjacent axial slices (multislice view). To evaluate the difference between the two techniques, we used the Wilcoxon test. To evaluate the correlation between the cerebellum and cisterna magna length measurements and the gestational age, we used the Spearman correlation coefficient (r). For the calculation of reproducibility, we used the intraclass correlation coefficient (ICC). The mean of the transverse and anterior-posterior diameter of cerebellum and cisterna magna by 3DUS was 9.23 and 6.62 mm, respectively. It was observed that the average of the measurements obtained by 3DUS was significantly higher, 0.76 and 1.02 mm for the length of the cerebellum and cisterna magna, respectively (P<0.001). There was a high correlation between the length measurement of the cerebellum 3D (r=0.940, P<0.001), but low correlation of cisterna magna 3D (r=0.462, P=0.080) with the gestational age. There was good intra- and interobserver reproducibility for the cerebellum and cisterna magna 3D with ICC=0.792 , 0.668, 0.691, and 0.287, respectively. The measurements of the fetal cerebellum and cisterna magna length by 3DUS using the software 3D XI were significantly higher than those obtained by 2DUS.


Author(s):  
Jamalodin Tabibi ◽  
Alireza Kiani

Background: Medical equipment plays a key role in diagnosis, treatment, and medical education. Outsourcing is delegating a part or all activities of an organization to a party (e.g., individuals or organizations) outside the organization, which has an important role in the organization’s productivity. Objectives: The current study aimed to investigate the effect of outsourcing the department of medical equipment of a university hospital in Tehran, Iran, by emphasizing costs, profits, and performance. Methods: This was a descriptive-analytical and cross-sectional study. This study investigated the documents and financial records of the Financial Office to calculate costs and revenues. Additionally, a researcher-developed questionnaire was used to evaluate the effect of outsourcing on employees’ performance and financial performance. A total of 36 subjects were randomly selected, following the sampling formula (the response rate: 72%). The Kolmogorov-Smirnov test was applied to test for a normal distribution. As the data were not normally distributed, the Wilcoxon test was used. Furthermore, the t-test and analysis of variance were used to study the difference in the effect of outsourcing and age, gender, and educational level. The data were analyzed using SPSS software (version 19). Results: According to the findings, there was a significant difference before and after outsourcing in the costs and revenues of the Medical Equipment Department. Concerning the effect of outsourcing on the performance, the “human resources” factor obtained the highest mean (3.37), which indicated the poor perspective of the staff in this aspect. Moreover, the lowest score was related to the “cost-effectiveness” (2.96), which was an average score. There were weak scores concerning the dimensions of management (3.28) and quality of services (3.36). Conclusions: Considering the importance of staff in the hospital, it is necessary to pay serious attention to the impact of different types of reforms intended to increase the revenues and reduce the costs of hospitals on the staff of the organization by emphasizing managerial and human resources dimensions, which not only will increase the efficiency of the organization and satisfaction of the staff but also translated into better quality.


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